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Aliases for C10orf131 Gene

Aliases for C10orf131 Gene

  • Chromosome 10 Open Reading Frame 131 2 3
  • Coiled-Coil And C2 Domain Containing 2B 5
  • Uncharacterized Protein C10orf131 3
  • BA690P14.3 3
  • CC2D2B 5

External Ids for C10orf131 Gene

Previous GeneCards Identifiers for C10orf131 Gene

  • GC10U900547
  • GC10P097657
  • GC10P091295
  • GC10P097620
  • GC10P097667

Summaries for C10orf131 Gene

GeneCards Summary for C10orf131 Gene

C10orf131 (Chromosome 10 Open Reading Frame 131) is a Protein Coding gene. An important paralog of this gene is CC2D2A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C10orf131 Gene

Genomics for C10orf131 Gene

Regulatory Elements for C10orf131 Gene

Enhancers for C10orf131 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10F095829 1.7 FANTOM5 Ensembl ENCODE 11.2 -73.0 -73045 9.9 HDGF PKNOX1 WRNIP1 SIN3A YBX1 YY1 ZNF121 ZNF143 ZNF207 FOS ENTPD1 TCTN3 C10orf131 ENTPD1-AS1 ALDH18A1 ENSG00000240527 ENSG00000282889
GH10F095781 1.6 FANTOM5 Ensembl ENCODE 9.9 -122.0 -121991 8.0 HDGF PKNOX1 WRNIP1 ZFP64 SIN3A ZNF2 ZNF121 GLIS2 FOS ZNF263 ENTPD1 TCTN3 C10orf131 CC2D2B BLNK GC10M095714
GH10F095755 1.4 FANTOM5 ENCODE 10.5 -148.5 -148541 8.0 HDGF PKNOX1 ATF1 WRNIP1 SIN3A YBX1 YY1 ELK1 ZNF143 ZNF207 ENTPD1 C10orf131 CC2D2B TCTN3 ALDH18A1 GC10M095714
GH10F095766 1.4 FANTOM5 Ensembl ENCODE 10.4 -138.8 -138823 4.1 HDGF SOX13 ELF3 PKNOX1 WRNIP1 CHD4 BMI1 RELA ZNF366 CBX5 ENTPD1 TCTN3 C10orf131 CC2D2B ENTPD1-AS1 ALDH18A1 ZNF518A GC10M095714
GH10F095817 1.4 FANTOM5 Ensembl ENCODE 10.3 -87.3 -87313 4.6 PKNOX1 TBL1XR1 WRNIP1 RAD21 SCRT2 ETV6 FOS JUNB TBX21 ETV4 ENTPD1 TCTN3 C10orf131 ALDH18A1 SORBS1 ENSG00000240527 GC10M095714
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C10orf131 on UCSC Golden Path with GeneCards custom track

Promoters for C10orf131 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000359805 -2 1999 PKNOX1 ARID4B SIN3A GLI4 DMAP1 ZNF48 ZNF2 ETS1 YY1 ZNF121

Genomic Location for C10orf131 Gene

95,907,603 bp from pter
96,032,684 bp from pter
125,082 bases
Plus strand

Genomic View for C10orf131 Gene

Genes around C10orf131 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C10orf131 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C10orf131 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C10orf131 Gene

Proteins for C10orf131 Gene

  • Protein details for C10orf131 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C10orf131
    Protein Accession:
    Secondary Accessions:
    • B1AMZ2
    • B4DG41

    Protein attributes for C10orf131 Gene

    256 amino acids
    Molecular mass:
    29615 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C10orf131 Gene


neXtProt entry for C10orf131 Gene

Post-translational modifications for C10orf131 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C10orf131 Gene

Domains & Families for C10orf131 Gene

Protein Domains for C10orf131 Gene


Suggested Antigen Peptide Sequences for C10orf131 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C10orf131: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C10orf131 Gene

Function for C10orf131 Gene

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C10orf131 Gene

Localization for C10orf131 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C10orf131 gene
Compartment Confidence
nucleus 3
cytosol 3

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C10orf131 Gene

Pathways & Interactions for C10orf131 Gene

SuperPathways for C10orf131 Gene

No Data Available

Interacting Proteins for C10orf131 Gene

Gene Ontology (GO) - Biological Process for C10orf131 Gene


No data available for Pathways by source and SIGNOR curated interactions for C10orf131 Gene

Transcripts for C10orf131 Gene

mRNA/cDNA for C10orf131 Gene

(2) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(10) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C10orf131 Gene

Chromosome 10 open reading frame 131:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C10orf131 Gene

No ASD Table

Relevant External Links for C10orf131 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C10orf131 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C10orf131 Gene

Protein differential expression in normal tissues from HIPED for C10orf131 Gene

This gene is overexpressed in Colon muscle (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C10orf131 Gene

Protein tissue co-expression partners for C10orf131 Gene

NURSA nuclear receptor signaling pathways regulating expression of C10orf131 Gene:


SOURCE GeneReport for Unigene cluster for C10orf131 Gene:

genes like me logo Genes that share expression patterns with C10orf131: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C10orf131 Gene

Orthologs for C10orf131 Gene

This gene was present in the common ancestor of animals.

Orthologs for C10orf131 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C10H10orf131 34
  • 99.61 (n)
-- 35
  • 99 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 58 (a)
(Monodelphis domestica)
Mammalia -- 35
  • 13 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 15 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG43370 35
  • 6 (a)
(Caenorhabditis elegans)
Secernentea mks-6 35
  • 7 (a)
Species where no ortholog for C10orf131 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for C10orf131 Gene

Gene Tree for C10orf131 (if available)
Gene Tree for C10orf131 (if available)

Paralogs for C10orf131 Gene

Paralogs for C10orf131 Gene

genes like me logo Genes that share paralogs with C10orf131: view

Variants for C10orf131 Gene

Sequence variations from dbSNP and Humsavar for C10orf131 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs10736095 -- 95,937,389(+) TGATA(C/T)ATTCA intron-variant
rs10748650 -- 95,910,437(+) gtcac(A/G)tggca intron-variant
rs10786240 -- 95,906,781(+) TGTTA(C/T)CAAGT intron-variant, upstream-variant-2KB
rs10786241 -- 95,908,552(+) AAAGG(A/T)TGGAG intron-variant
rs10786242 -- 95,909,045(+) GTCCT(C/G)AGAGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C10orf131 Gene

Variant ID Type Subtype PubMed ID
nsv477467 CNV novel sequence insertion 20440878
nsv25405 CNV deletion 16902084
nsv1110852 OTHER inversion 24896259
esv3321957 CNV insertion 20981092

Variation tolerance for C10orf131 Gene

Gene Damage Index Score: 1.32; 26.13% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C10orf131 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C10orf131 Gene

Disorders for C10orf131 Gene

Relevant External Links for C10orf131

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C10orf131 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C10orf131 Gene

Publications for C10orf131 Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4 64
  2. The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis. (PMID: 26687479) Oliviero G. … Cagney G. (Sci. Rep. 2015) 3 64
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 64

Products for C10orf131 Gene

Sources for C10orf131 Gene

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