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Aliases for C10orf126 Gene

Aliases for C10orf126 Gene

  • Chromosome 10 Open Reading Frame 126 2 3 5
  • Putative Uncharacterized Protein C10orf126 3
  • BA492M23.1 3

External Ids for C10orf126 Gene

Previous GeneCards Identifiers for C10orf126 Gene

  • GC00U916890
  • GC10U900733
  • GC10P029177

Summaries for C10orf126 Gene

GeneCards Summary for C10orf126 Gene

C10orf126 (Chromosome 10 Open Reading Frame 126) is a Protein Coding gene.

Additional gene information for C10orf126 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C10orf126 Gene

Genomics for C10orf126 Gene

Regulatory Elements for C10orf126 Gene

Enhancers for C10orf126 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10H028805 1.5 Ensembl ENCODE dbSUPER 11.4 -38.7 -38715 3.6 FOXA2 PKNOX1 ATF1 ARNT DMAP1 YY1 TCF12 ZNF766 GATA2 ELK1 ENSG00000271220 BAMBI RNU6-270P C10orf126 LINC01517 GC10M029918
GH10H028809 1.4 Ensembl ENCODE dbSUPER 11.7 -35.8 -35816 1.9 HDGF RB1 NFRKB FOS ZBTB11 CEBPB ELF1 ZNF592 TFDP1 ZNF589 ENSG00000271220 BAMBI C10orf126 RNU6-270P LYZL1 GC10M029918
GH10H029252 1.6 FANTOM5 Ensembl ENCODE 9.5 +409.1 409126 5.6 PKNOX1 ATF1 FEZF1 GLIS2 GATA2 ELK1 ATF7 SP3 TSHZ1 MEF2D LYZL1 C10orf126 RNU6-270P LOC105376472
GH10H028822 1.2 ENCODE dbSUPER 11.8 -23.2 -23232 1.5 HDGF PKNOX1 ATF1 ARNT ZFP64 TCF12 ZNF766 GATA2 ATF7 GTF2B C10orf126 BAMBI RNU6-270P ENSG00000271220 GC10M029918
GH10H028734 1.3 Ensembl ENCODE 10.8 -111.3 -111253 1.5 PKNOX1 FOXA2 ATF1 ARNT ARID4B SIN3A FEZF1 TCF12 GTF3C2 ZNF766 ENSG00000236716 RNU6-270P C10orf126 LINC01517 LOC105376470
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C10orf126 on UCSC Golden Path with GeneCards custom track

Genomic Locations for C10orf126 Gene

Genomic Locations for C10orf126 Gene
35,491 bases
Plus strand

Genomic View for C10orf126 Gene

Genes around C10orf126 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C10orf126 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C10orf126 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C10orf126 Gene

Proteins for C10orf126 Gene

  • Protein details for C10orf126 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative uncharacterized protein C10orf126
    Protein Accession:
    Secondary Accessions:
    • Q5T2Z8

    Protein attributes for C10orf126 Gene

    172 amino acids
    Molecular mass:
    19474 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C10orf126 Gene

Post-translational modifications for C10orf126 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C10orf126 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C10orf126 Gene

Domains & Families for C10orf126 Gene

Protein Domains for C10orf126 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C10orf126: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C10orf126 Gene

Function for C10orf126 Gene

Animal Model Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C10orf126 Gene

Localization for C10orf126 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C10orf126 gene
Compartment Confidence
plasma membrane 1
extracellular 1
mitochondrion 1
peroxisome 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C10orf126 Gene

Pathways & Interactions for C10orf126 Gene

SuperPathways for C10orf126 Gene

No Data Available

Interacting Proteins for C10orf126 Gene

Gene Ontology (GO) - Biological Process for C10orf126 Gene


No data available for Pathways by source and SIGNOR curated interactions for C10orf126 Gene

Drugs & Compounds for C10orf126 Gene

No Compound Related Data Available

Transcripts for C10orf126 Gene

mRNA/cDNA for C10orf126 Gene

(2) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C10orf126 Gene

Chromosome 10 open reading frame 126:
Representative Sequences:

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for C10orf126 Gene

No ASD Table

Relevant External Links for C10orf126 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C10orf126 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C10orf126 Gene

mRNA differential expression in normal tissues according to GTEx for C10orf126 Gene

This gene is overexpressed in Kidney - Cortex (x19.8), Testis (x13.5), and Liver (x7.1).

Protein differential expression in normal tissues from HIPED for C10orf126 Gene

This gene is overexpressed in Lung (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C10orf126 Gene

Protein tissue co-expression partners for C10orf126 Gene

NURSA nuclear receptor signaling pathways regulating expression of C10orf126 Gene:


SOURCE GeneReport for Unigene cluster for C10orf126 Gene:

genes like me logo Genes that share expression patterns with C10orf126: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C10orf126 Gene

Orthologs for C10orf126 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C10orf126 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC101059856 33
  • 99.22 (n)
C10orf126 34
  • 99 (a)
Species where no ortholog for C10orf126 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C10orf126 Gene

Gene Tree for C10orf126 (if available)
Gene Tree for C10orf126 (if available)

Paralogs for C10orf126 Gene

No data available for Paralogs for C10orf126 Gene

Variants for C10orf126 Gene

Sequence variations from dbSNP and Humsavar for C10orf126 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs1000030558 -- 28,847,585(+) TCCCA(A/G)CTACT intron-variant
rs1000084347 -- 28,866,591(+) GAAGC(C/T)GACAG intron-variant
rs1000091861 -- 28,881,012(+) AAATT(C/T)GTAAA utr-variant-3-prime
rs1000131475 -- 28,872,522(+) AAGAT(-/A)AAAAA intron-variant
rs1000287370 -- 28,863,575(+) TGTAT(A/G)TGTGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C10orf126 Gene

Variant ID Type Subtype PubMed ID
nsv1142091 CNV tandem duplication 24896259
esv3578745 CNV loss 25503493
esv3344326 CNV insertion 20981092
esv2734606 CNV deletion 23290073

Variation tolerance for C10orf126 Gene

Gene Damage Index Score: 0.72; 15.31% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C10orf126 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C10orf126 Gene

Disorders for C10orf126 Gene

Relevant External Links for C10orf126

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C10orf126 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C10orf126 Gene

Publications for C10orf126 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  3. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 4 60
  4. The sequence of the human genome. (PMID: 11181995) Venter JC … Zhu X (Science (New York, N.Y.) 2001) 3 60

Products for C10orf126 Gene

Sources for C10orf126 Gene

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