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Aliases for C10orf120 Gene

Aliases for C10orf120 Gene

  • Chromosome 10 Open Reading Frame 120 2 3 5
  • Uncharacterized Protein C10orf120 3
  • BA318C4.1 3

External Ids for C10orf120 Gene

Previous GeneCards Identifiers for C10orf120 Gene

  • GC10M123998
  • GC10M124447
  • GC10M118075

Summaries for C10orf120 Gene

GeneCards Summary for C10orf120 Gene

C10orf120 (Chromosome 10 Open Reading Frame 120) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C10orf120 Gene

Genomics for C10orf120 Gene

Regulatory Elements for C10orf120 Gene

Enhancers for C10orf120 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10F123304 0.5 ENCODE 11.1 -604.3 -604348 0.1 PKNOX1 INSM2 FEZF1 GLIS2 ZNF366 SCRT2 KLF7 OVOL3 ZNF488 TSHZ1 ENSG00000234542 FAM24A ENSG00000234677 C10orf120 GC10P123316 GC10P123258
GH10F121926 0.2 ENCODE 11.1 +771.0 771018 5.3 HDGF PKNOX1 WRNIP1 SIN3A DMAP1 ZNF2 YY1 ZNF207 ZNF143 SP3 ATE1-AS1 ENSG00000224250 RPL19P16 LINC01153 FAM24A NSMCE4A ATE1 C10orf120 GC10P121933
GH10F122688 0.8 ENCODE 0.4 +10.9 10859 0.9 CTCF GLIS2 GABPB1 RAD21 NR2F2 EZH2 C10orf120 GC10M122639
GH10F122689 1.1 ENCODE 0.4 +10.2 10223 0.2 ZNF335 GLIS2 KLF9 REST EZH2 C10orf120 GC10M122639
GH10F122690 0.8 ENCODE 0.4 +11.4 11399 0.1 GABPB1 NR2F2 EZH2 C10orf120 GC10M122639
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C10orf120 on UCSC Golden Path with GeneCards custom track

Genomic Location for C10orf120 Gene

Chromosome:
10
Start:
122,697,709 bp from pter
End:
122,699,822 bp from pter
Size:
2,114 bases
Orientation:
Minus strand

Genomic View for C10orf120 Gene

Genes around C10orf120 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C10orf120 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C10orf120 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C10orf120 Gene

Proteins for C10orf120 Gene

  • Protein details for C10orf120 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5SQS8-CJ120_HUMAN
    Recommended name:
    Uncharacterized protein C10orf120
    Protein Accession:
    Q5SQS8
    Secondary Accessions:
    • B2RU17

    Protein attributes for C10orf120 Gene

    Size:
    335 amino acids
    Molecular mass:
    39268 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C10orf120 Gene

Post-translational modifications for C10orf120 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C10orf120 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C10orf120 Gene

Domains & Families for C10orf120 Gene

Protein Domains for C10orf120 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C10orf120: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C10orf120 Gene

Function for C10orf120 Gene

genes like me logo Genes that share phenotypes with C10orf120: view

Animal Models for C10orf120 Gene

MGI Knock Outs for C10orf120:

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for C10orf120 Gene

Localization for C10orf120 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C10orf120 Gene COMPARTMENTS Subcellular localization image for C10orf120 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for C10orf120 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000151 ubiquitin ligase complex IBA --
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with C10orf120: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C10orf120 Gene

Pathways & Interactions for C10orf120 Gene

SuperPathways for C10orf120 Gene

No Data Available

Interacting Proteins for C10orf120 Gene

Gene Ontology (GO) - Biological Process for C10orf120 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C10orf120 Gene

Transcripts for C10orf120 Gene

mRNA/cDNA for C10orf120 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C10orf120 Gene

Chromosome 10 open reading frame 120:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C10orf120 Gene

No ASD Table

Relevant External Links for C10orf120 Gene

GeneLoc Exon Structure for
C10orf120
ECgene alternative splicing isoforms for
C10orf120

Expression for C10orf120 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C10orf120 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C10orf120 Gene

This gene is overexpressed in Testis (x51.9).

Protein differential expression in normal tissues from HIPED for C10orf120 Gene

This gene is overexpressed in Fetal ovary (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C10orf120 Gene



Protein tissue co-expression partners for C10orf120 Gene

NURSA nuclear receptor signaling pathways regulating expression of C10orf120 Gene:

C10orf120

SOURCE GeneReport for Unigene cluster for C10orf120 Gene:

Hs.363649
genes like me logo Genes that share expression patterns with C10orf120: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for C10orf120 Gene

Orthologs for C10orf120 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C10orf120 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C10H10orf120 34
  • 99.1 (n)
C10orf120 35
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C28H10orf120 34
  • 74.75 (n)
C10orf120 35
  • 62 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C26H10orf120 34 35
  • 73.33 (n)
mouse
(Mus musculus)
Mammalia 4933402N03Rik 34 16 35
  • 65.93 (n)
rat
(Rattus norvegicus)
Mammalia LOC499276 34
  • 65.74 (n)
oppossum
(Monodelphis domestica)
Mammalia C10orf120 35
  • 46 (a)
OneToOne
Species where no ortholog for C10orf120 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C10orf120 Gene

ENSEMBL:
Gene Tree for C10orf120 (if available)
TreeFam:
Gene Tree for C10orf120 (if available)

Paralogs for C10orf120 Gene

No data available for Paralogs for C10orf120 Gene

Variants for C10orf120 Gene

Sequence variations from dbSNP and Humsavar for C10orf120 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs10902922 -- 122,699,219(+) CAATG(G/T)GAGTC intron-variant
rs10902929 -- 122,700,553(+) TCAAA(A/G)GTGTG upstream-variant-2KB
rs112033476 -- 122,700,079(+) CAGTT(C/T)TCACA upstream-variant-2KB
rs11248391 -- 122,697,349(+) CATGA(A/G)GAACC downstream-variant-500B
rs11248476 -- 122,699,005(+) ggcgg(G/T)cgcct intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C10orf120 Gene

Variant ID Type Subtype PubMed ID
nsv509370 CNV insertion 20534489
nsv7584 CNV insertion 18451855

Variation tolerance for C10orf120 Gene

Residual Variation Intolerance Score: 75.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.23; 62.24% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C10orf120 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C10orf120

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C10orf120 Gene

Disorders for C10orf120 Gene

Relevant External Links for C10orf120

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C10orf120

No disorders were found for C10orf120 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C10orf120 Gene

Publications for C10orf120 Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for C10orf120 Gene

Sources for C10orf120 Gene

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