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Aliases for C10orf12 Gene

Aliases for C10orf12 Gene

  • Chromosome 10 Open Reading Frame 12 2 3 5

External Ids for C10orf12 Gene

Previous GeneCards Identifiers for C10orf12 Gene

  • GC10P098405
  • GC10P098731
  • GC10P092369

Summaries for C10orf12 Gene

GeneCards Summary for C10orf12 Gene

C10orf12 (Chromosome 10 Open Reading Frame 12) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C10orf12 Gene

Genomics for C10orf12 Gene

Regulatory Elements for C10orf12 Gene

Enhancers for C10orf12 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C10orf12 on UCSC Golden Path with GeneCards custom track

Genomic Location for C10orf12 Gene

96,981,284 bp from pter
96,986,212 bp from pter
4,929 bases
Plus strand

Genomic View for C10orf12 Gene

Genes around C10orf12 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C10orf12 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C10orf12 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C10orf12 Gene

Proteins for C10orf12 Gene

  • Protein details for C10orf12 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C10orf12
    Protein Accession:
    Secondary Accessions:
    • Q9H945
    • Q9Y457

    Protein attributes for C10orf12 Gene

    1247 amino acids
    Molecular mass:
    137223 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB14396.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for C10orf12 Gene

Proteomics data for C10orf12 Gene at MOPED

Post-translational modifications for C10orf12 Gene

  • Ubiquitination at Lys 813
  • Modification sites at PhosphoSitePlus

Other Protein References for C10orf12 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C10orf12 Gene

Domains & Families for C10orf12 Gene

Protein Domains for C10orf12 Gene


Suggested Antigen Peptide Sequences for C10orf12 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C10orf12: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C10orf12 Gene

Function for C10orf12 Gene

Phenotypes for C10orf12 Gene

GenomeRNAi human phenotypes for C10orf12:
genes like me logo Genes that share phenotypes with C10orf12: view

Animal Model Products

CRISPR Products

miRNA for C10orf12 Gene

miRTarBase miRNAs that target C10orf12

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C10orf12 Gene

Localization for C10orf12 Gene

Subcellular locations from

Jensen Localization Image for C10orf12 Gene COMPARTMENTS Subcellular localization image for C10orf12 gene
Compartment Confidence
nucleus 4
cytosol 3

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C10orf12 Gene

Pathways & Interactions for C10orf12 Gene

SuperPathways for C10orf12 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C10orf12 Gene


No data available for Pathways by source and SIGNOR curated interactions for C10orf12 Gene

Drugs & Compounds for C10orf12 Gene

No Compound Related Data Available

Transcripts for C10orf12 Gene

mRNA/cDNA for C10orf12 Gene

(1) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(43) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C10orf12 Gene

Chromosome 10 open reading frame 12:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C10orf12 Gene

No ASD Table

Relevant External Links for C10orf12 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C10orf12 Gene

mRNA expression in normal human tissues for C10orf12 Gene

Protein differential expression in normal tissues from HIPED for C10orf12 Gene

This gene is overexpressed in Breast (30.0), Cervix (20.1), and Amniocyte (11.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for C10orf12 Gene

SOURCE GeneReport for Unigene cluster for C10orf12 Gene Hs.14555

genes like me logo Genes that share expression patterns with C10orf12: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C10orf12 Gene

Orthologs for C10orf12 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C10orf12 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LCOR 35
  • 83.51 (n)
  • 77.03 (a)
C10orf12 36
  • 77 (a)
(Canis familiaris)
Mammalia LCOR 35
  • 85.86 (n)
  • 80.84 (a)
C10orf12 36
  • 71 (a)
(Rattus norvegicus)
Mammalia Lcor 35
  • 72.24 (n)
  • 62.57 (a)
(Monodelphis domestica)
Mammalia C10orf12 36
  • 72 (a)
(Mus musculus)
Mammalia Gm340 36
  • 64 (a)
(Ornithorhynchus anatinus)
Mammalia C10orf12 36
  • 49 (a)
(Pan troglodytes)
Mammalia C10orf12 36
  • 99 (a)
(Gallus gallus)
Aves -- 36
  • 42 (a)
-- 36
  • 79 (a)
(Anolis carolinensis)
Reptilia C10orf12 36
  • 39 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.17506 35
(Danio rerio)
Actinopterygii C1H10orf12 36
  • 10 (a)
Species with no ortholog for C10orf12:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C10orf12 Gene

Gene Tree for C10orf12 (if available)
Gene Tree for C10orf12 (if available)

Paralogs for C10orf12 Gene Pseudogenes for C10orf12 Gene

genes like me logo Genes that share paralogs with C10orf12: view

No data available for Paralogs for C10orf12 Gene

Variants for C10orf12 Gene

Sequence variations from dbSNP and Humsavar for C10orf12 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs11188980 - 96,981,536(+) GGGGA(A/G)CTCAT reference, missense
rs7082522 - 96,982,331(+) TCACC(C/T)TCCTG reference, missense
rs34104025 - 96,982,591(-) CATTG(C/G)GGAAC reference, missense
rs3829856 - 96,982,993(+) TTGAA(A/C)TCAAA reference, missense
rs35128733 - 96,982,577(-) GATTT(C/T)CTGAG reference, missense

Structural Variations from Database of Genomic Variants (DGV) for C10orf12 Gene

Variant ID Type Subtype PubMed ID
nsv831951 CNV Gain 17160897

Variation tolerance for C10orf12 Gene

Residual Variation Intolerance Score: 49.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.01; 74.93% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for C10orf12 Gene

Disorders for C10orf12 Gene

Relevant External Links for C10orf12

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C10orf12 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C10orf12 Gene

Publications for C10orf12 Gene

  1. Reciprocal interactions of human C10orf12 and C17orf96 with PRC2 revealed by BioTAP-XL cross-linking and affinity purification. (PMID: 24550272) Alekseyenko A.A. … Kuroda M.I. (Proc. Natl. Acad. Sci. U.S.A. 2014) 2 3 67
  2. Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes. (PMID: 25281560) Lambert J.P. … Gingras A.C. (J Proteomics 2015) 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  5. The central role of EED in the orchestration of polycomb group complexes. (PMID: 24457600) Cao Q. … Chinnaiyan A.M. (Nat Commun 2014) 3

Products for C10orf12 Gene

Sources for C10orf12 Gene