C10orf118 Gene
protein-coding GIFtS: 44
GCID: GC10M115871
|
|
chromosome 10 open reading frame 118
| |
Aliases
for C10orf118 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 10 Open Reading Frame 1181 2 | | CTCL Tumor Antigen HD-CL-01/L14-22 3 | | FLJ101881 | | FLJ353011 | | CTCL Tumor Antigen L14-22 | | Uncharacterized Protein C10orf1182 |
Export aliases for C10orf118 gene to outside databasesPrevious GC identifers: GC10M115547 GC10M109509 |
Summaries
for C10orf118 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Gene Wiki entry for C10orf118
|
Genomic Views
for C10orf118 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.1 NT_030059.13
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C10orf118 gene promoter:
Egr-3 Pax-5 Gfi-1 FOXL1 RORalpha1 Egr-2 Max IRF-2 ARP-1 c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for C10orf118
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C10orf118 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10q25.3 Ensembl cytogenetic band: 10q25.3 HGNC cytogenetic band: 10q26.11C10orf118 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10M115871: view genomic region
(about GC identifiers)
Start:
|
115,880,621 bp from pter |
End:
|
115,934,364 bp from pter |
Size:
|
53,744 bases |
Orientation:
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minus strand |
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Proteins
for C10orf118 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CJ118_HUMAN, Q7Z3E2 (See
protein sequence)Recommended Name: Uncharacterized protein C10orf118 Size: 898 amino acids; 103687 Da
Sequence caution: Sequence=AAH70368.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-Asequence starting in position 212; Sequence=AAM44457.1; Type=Erroneous initiation; Note=Translation N-terminallyextended; Sequence=AAM44457.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequencestarting in position 792; Sequence=BAA91480.1; Type=Erroneous initiation; Sequence=BAC03926.1; Type=Miscellaneousdiscrepancy; Note=Intron retention;
Secondary accessions: Q2M2V6 Q3ZB81 Q6NS91 Q7RTP1 Q8N117 Q8N3G3 Q8N6C2 Q9NWA3Explore the universe of human proteins at neXtProt for C10orf118: NX_Q7Z3E2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q7Z3E2
C10orf118 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_060487.2
ENSEMBL proteins: ENSP00000358293 ENSP00000415344 ENSP00000358292 ENSP00000358291 ENSP00000441576
Human Recombinant Protein Products:
C10orf118 Antibody Products:
Assay Products for C10orf118: |
Protein
Domains /
Families
for C10orf118 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q7Z3E2 |
Function
for C10orf118 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf118 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf118
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C10orf118 (NM_018017) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C10orf118 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C10orf118 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C10orf118 |
1 GenomeRNAi human phenotype for C10orf118:
|
Pathways & Interactions
for C10orf118 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C10orf118
STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)
5 Interacting proteins for C10orf118 (Q7Z3E22, 3 ENSP000003582934) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for C10orf118 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C10orf118
Search CenterWatch for drugs/clinical trials and news about C10orf118 / CJ118
|
Transcripts
for C10orf118 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C10orf118 gene: NM_018017.2 Unigene Cluster for C10orf118: Chromosome 10 open reading frame 118 Hs.159066 [show with all ESTs]Unigene Representative Sequence: NM_0180177 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000369287(uc009xyd.1 uc001lbb.1 uc001lbc.1 uc009xye.1)
ENST00000428953 ENST00000497592 ENST00000490661 ENST00000369286(uc001lbe.3)
ENST00000369285(uc001lbd.3) ENST00000543782
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf118 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf118
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C10orf118 (NM_018017) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C10orf118 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C10orf118 |
Additional cDNA sequence: AF273054.1 AK001050.1 AK024739.1 AK057508.1 AK092620.1 AK094498.1 AK307517.1 AL834368.1 BC020842.1 BC022229.1 BC070368.1 BC100670.1 BC103499.1 BC103504.1 BC105632.1 BC107430.1 BC152306.1 BX537964.1 8 DOTS entries: DT.100716575 DT.304234 DT.92418292 DT.92057946 DT.121229321 DT.121229338 DT.97782920 DT.95336207 24/135 AceView cDNA sequences (see all 135): AI984325 BX091088 AI093252 BC030557 AI292113 NM_018017 BE222725 BX537964 AI382501 AX747632 AI950749 BX498831 AA370778 AI655195 AK094498 AI862150 BF515627 BK001329 AA885835 BE221489 BX111831 AW291511 CK430370 BC022229
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for C10orf118 (see all 9) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b | ^ | 17a | · | 17b | · |
|---|
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| SP1: | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | - | | | | | | | | - | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 17c | · | 17d | ^ | 18 | ^ | 19 |
|---|
|
| SP1: | | | | | | | | | |
| SP2: | | | | | | | | | |
| SP3: | | | | | | | | | |
| SP4: | | | | | | | | | |
| SP5: | | | | | | | | |
ECgene alternative splicing isoforms for C10orf118
|
Expression
for C10orf118 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C10orf118 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGAATTTTT
About this image
See C10orf118 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C10orf118
SOURCE GeneReport for Unigene cluster: Hs.159066
SABiosciences Custom PCR Arrays for C10orf118
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C10orf118
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C10orf118 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C10orf118 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C10orf118 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C10orf118 |
Orthologs
for C10orf118 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for C10orf118 gene from 7/22 species (see all 22) About this table
ENSEMBL Gene Tree for C10orf118 (if available)
TreeFam Gene Tree for C10orf118 (if available) |
Paralogs
for C10orf118 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C10orf118 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 10 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C10orf118 (115880621 - 115934364 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C10orf118: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C10orf118 |
|
Disorders
/ Diseases
for C10orf118 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
C10orf118 for disorders About GeneDecksing
1  disease for C10orf118: About MalaCardscutaneous t cell lymphoma
Export disorders for C10orf118 gene to outside databases
|
Publications
for C10orf118 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C10orf118 gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with C10orf118) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Gene discovery in the hamster: a comparative genomics approach for gene annotation by sequencing of hamster testis cDNAs. (PubMed id 12783626)1, 2, 3 Oduru S....Williams S.C. (2003)
- SEREX identification of new tumour-associated antigens in cutaneous T-cell lymphoma. (PubMed id 14996095)1, 2 Hartmann T.B.... Eichmueller S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
- A human MAP kinase interactome. (PubMed id 20936779)1 Bandyopadhyay S....Ideker T. (2010)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (2006)
|
External Searches for C10orf118 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C10orf118 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C10orf118 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C10orf118 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for C10orf118 gene:
Search GeneIP for patents involving C10orf118
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C10orf118 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C10orf118 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C10orf118 | | | OriGene Protein Over-expression Lysate for C10orf118 | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for C10orf118 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf118 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf118 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C10orf118 | | OriGene Custom Protein Services for C10orf118 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C10orf118 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C10orf118 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C10orf118 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C10orf118 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C10orf118 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C10orf118 |
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 | | | C10orf118 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C10orf118 |
|  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C10orf118 |
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