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Aliases &
Descriptions
for C10orf116
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases |
|---|
| APM2 1, 2 | | OTTHUMP00000020019 2 | | apM-2 3 |
| | | Descriptions |
|---|
| adipose specific 2 2 | | chromosome 10 open reading frame 116 2 |
|
| |
Search outside databases for aliases for C10orf116 genePrevious GC identifer: GC10P088393 |
Summaries
for C10orf116(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| EntrezGene summary for C10orf116:
APM2 gene is exclusively expressed in adipose tissue. Its function is currently unknown. [provided
by RefSeq]
|
Genomic Location
for C10orf116
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences)
About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
 Transcription factor binding sites upstream to the C10orf116 gene 
Entrez Gene cytogenetic band: 10q23.2 Ensembl cytogenetic band: 10q23.2 HGNC cytogenetic band: 10q23.31C10orf116 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10P088718:
(about GC identifiers)
Start:
|
88,718,168 bp from pter |
End:
|
88,720,646 bp from pter |
Size:
|
2,479 bases |
Orientation:
|
plus strand |
RefSeq DNA sequence:- NC_000010.9 NT_030059.12
| Proteins
for C10orf116
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: APM2_HUMAN, Q15847 (See
protein sequence)Recommended Name: Adipose most abundant gene transcript 2 protein Size: 76 amino acids; 7855 DaREFSEQ proteins: NP_006820.1
ENSEMBL proteins: ENSP00000361083 ENSP00000361082
Human Recombinant Proteins  OriGene Purified Recombinant Human Protein: C10orf116
1 Gene Ontology (GO) cellular component term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005575 | cellular_component |
ND | -- |
About this table
Antibodies for C10orf116:
Assays for C10orf116: | Protein
Domains/
Families
for C10orf116(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q15847 | Gene Function
for C10orf116
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_006829
 Applied Biosystems Silencer® siRNAs for C10orf116
 Sigma-Aldrich siRNA for C10orf116
Sigma-Aldrich shRNA for C10orf116
Explore Sigma-Aldrich super-pooled esiRNAs
OriGene GFP tagged cDNA clone in CMV expression vector: NM_006829
Myc/DDK tagged cDNA clone in CMV expression vector: NM_006829
untagged cDNA clone in CMV expression vector: NM_006829
Primers:  Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
OriGene genome-wide validated SYBR primer pairs: NM_006829
1 Gene Ontology (GO) molecular function term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003674 | molecular_function |
ND | -- |
About this table | Pathways & Interactions
for C10orf116
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
2 Interacting proteins for C10orf116 (ENSP000003610833) via UniProtKB, MINT, and/or STRINGAbout this table
1 Gene Ontology (GO) biological process term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008150 | biological_process |
ND | -- |
About this table
|
Drugs & Compounds
for C10orf116(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for C10orf116
|
Transcripts
for C10orf116(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene,
Expression Assays from Applied Biosystems)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_006829
Sigma-Aldrich siRNA for C10orf116
Sigma-Aldrich shRNA for C10orf116
Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer® siRNAs: NM_006829 REFSEQ mRNAs for C10orf116 gene: NM_006829.2
Applied Biosystems TaqMan ® Gene Expression Assays: NM_006829
OriGene GFP tagged cDNA clone in CMV expression vector: NM_006829
Myc/DDK tagged cDNA clone in CMV expression vector: NM_006829
untagged cDNA clone in CMV expression vector: NM_006829
Additional cDNA sequence: AK312031.1 BC004471.2 D45370.1 8 DOTS entries: DT.416147 DT.87002429 DT.86995906 DT.100058139 DT.91751907 DT.95202961 DT.100035487 DT.99952584 24/267 AceView cDNA sequences (see all 267
):AW006481 BI836596 CA434240 CR541788 AA878084 AA486472 H49348 BE566379 BM668990 BM748818 CB045310 AI637713 BM693306 BU728272 NM_006829 AJ346418 BG413520 BQ694475 BE299889 BM838642 CB107161 F30398 AI434794 BM704419
 highest scoring ESTs for C10orf116:AI381790 AA319916 AA320701 AA327611 AA335295 AA364498 AA371783 AA459680 AA478298 AA507134 Unigene Cluster for C10orf116: Chromosome 10 open reading frame 116 Hs.642660 [show with all ESTs]Unigene Representative Sequence: CD511450
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for C10orf116
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b |
|---|
|
| SP1: | | | | | | | | | | | |
| SP2: | | | | | - | | | | | |
About this scheme
ECgene alternative splicing isoforms for C10orf116
2 Ensembl transcripts including schematic representations: ENST00000372013
ENST00000372012
|
Expression
for C10orf116
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| C10orf116 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for C10orf116
1 / 2 / 3 3 probe-sets matching C10orf116 gene Data from
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.642660
Expression variation in blood from EXPOLDB for C10orf116 UniProtKB/Swiss-Prot: APM2_HUMAN, Q15847Tissue specificity: Expressed in adipose tissue, cornea and liver |
Orthologs
for C10orf116
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for C10orf116 gene from 2 species
| Organism |
Gene |
Locus |
Description |
Human
Similarity |
NCBI accessions |
chimpanzee
(Pan troglodytes) |
LOC7361951 |
-- |
hypothetical protein LOC736195 |
97.75(n)
97.18(a) |
736195 XM_001136008.1 XP_001136008.1 |
cow
(Bos taurus) |
C28H10ORF1161 |
-- |
chromosome 10 open reading frame 116 ortholog |
88.16(n)
85.53(a) |
613941 XM_865016.2 XP_870109.1 |
About this table Species with no ortholog for C10orf116
ENSEMBL Gene Tree for C10orf116 | Paralogs
for C10orf116(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| -- |
SNPs/Variants
for C10orf116(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
| -- |
Disorders & Mutations
for C10orf116
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
| Human Genome Epidemiology Navigator: C10orf116 (1 document)
|
Medical News
for C10orf116(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for C10orf116 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 5 PubMed articles for C10orf116 gene: |
Search for C10orf116
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C10orf116
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing C10orf116
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C10orf116(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| About This Section
| --
| Services
for C10orf116(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section
| 
Products for C10orf116:
 | |
 | | | | |
 |
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|  | Recombinant Proteins
(APM2) | | | Antibodies (APM2) |
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GeneCards Homepage - Last full update: 1 Jul 2009
Incremental update: 13 Oct 2009
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