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C10orf113 Gene

protein-coding   GIFtS: 34

GC10M021455
chromosome 10 open reading frame 113
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    
(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases
OTTHUMP00000019267 2
bA165O3.1 1, 2
Descriptions
chromosome 10 open reading frame 113 2
hypothetical protein LOC387638 2
External Ids
HGNC: 314471
Entrez Gene: 3876382
UniProtKB: Q5VZT23
Ensembl: ENSG000002046837
Search outside databases for aliases for C10orf113 gene

Previous GC identifer: GC10M021418

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

  --
(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
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Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the C10orf113 gene  

Entrez Gene cytogenetic band: 10p12.31   Ensembl cytogenetic band:  10p12.31   HGNC cytogenetic band: 10p12.33

C10orf113 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M021455:     (about GC identifiers)

Start:
21,454,698 bp from pter
End:
21,475,433 bp from pter
Size:
20,736 bases
Orientation:
minus strand
RefSeq DNA sequence:
NC_000010.9  NT_008705.15  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: CJ113_HUMAN, Q5VZT2 (See protein sequence)
Recommended Name: Putative uncharacterized protein C10orf113  
Size: 145 amino acids; 16466 Da
Caution: Encoded in intron of the NEBL gene. Confirmed by only 1 EST (AI806552)

REFSEQ proteins: NP_001010896.1  

ENSEMBL proteins: 
ENSP00000366322 


Human Recombinant Proteins 
Browse Drug Discovery Central at Invitrogen for human recombinant proteins
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Browse Abnova for Human Recombinant Proteins
                Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 


Antibodies for C10orf113: 
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Search Novus for antibodies for C10orf113

Assays for C10orf113: 
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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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ProtoNet protein and cluster: Q5VZT2

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib.
RNA:
Invitrogen RNAi Products for gene knock-down (C10orf113)
Browse for Gene Knock-down Tools from Millipore
Browse Abnova for Chimera RNAi Products
              OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001010896

              Applied Biosystems Silencer® siRNAs for C10orf113

              Sigma-Aldrich siRNA for C10orf113  
                     Sigma-Aldrich shRNA for C10orf113  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Clones:Browse Clone Ranger at Invitrogen for clones
Browse Clones for the Expression of Recombinant Proteins Available from Millipore
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001010896
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001010896
                                 untagged cDNA clone in CMV expression vector: NM_001010896 

Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
              OriGene genome-wide validated SYBR primer pairs: NM_001010896

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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  --
(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences
Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for C10orf113

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib.
RNA:
Invitrogen RNAi Products for gene knock-down (C10orf113)
Browse for Gene Knock-down Tools from Millipore
Browse Abnova for Chimera RNAi Products
              OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001010896

              Sigma-Aldrich siRNA for C10orf113  
                     Sigma-Aldrich shRNA for C10orf113  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Applied Biosystems Silencer® siRNAs: 

NM_001010896  

REFSEQ mRNAs for C10orf113 gene: 

NM_001010896.1   

Applied Biosystems TaqMan ® Gene Expression Assays: 

NM_001010896  

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001010896
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001010896
                                 untagged cDNA clone in CMV expression vector: NM_001010896 

Additional cDNA sequence: 

BC140744.1 BC144447.1 

2 DOTS entries:

DT.202881  DT.75107737 

6 AceView cDNA sequences:

BF057822 AI806552 AA923756 AA621285 BE065033 BE065034 

highest scoring ESTs for C10orf113:

AA621285 AA923756 AI806552 BE002846 BE065033 BE065034 BF057822 DB068425 DB233891 NM_001010896 

Unigene Cluster for C10orf113:

Chromosome 10 open reading frame 113
Hs.664110  [show with all ESTs]
Unigene Representative Sequence: BF057822


GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:
ENST00000377118  
(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

C10orf113 expression in normal and diseased human tissues

 Applied Biosystems TaqMan ® Gene Expression Assays for C10orf113

1 / 2 / 3

3 probe-sets matching C10orf113 gene


Affymetrix
probe-set
Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank

47186_at2, 3 U95-B 1 0.56 1.00 1.00 1.00 AA621285 0.60 0.75 0.68 1

244077_at2, 3 U133-B 1 0.27 1.00 -- -- BF057822 0.40 0.67 0.55 1

244077_at2 U133Plus2 1 0.27 1.00 -- -- -- -- -- -- --
About this table
Data from (Publications) and GNF BioGPS
    About these images
About these images

CGAP SAGE TAG: GATTTAAATT

SOURCE GeneReport for Unigene cluster: Hs.664110
(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section


Orthologs for C10orf113 gene from 1 species
Organism Gene Locus Description Human
Similarity
NCBI accessions
chimpanzee
(Pan troglodytes)
LOC4503401   -- hypothetical LOC450340 99.08(n)
97.24(a)
450340  XM_529299.2  XP_529299.2 
About this table        Species with no ortholog for C10orf113

ENSEMBL Gene Tree for C10orf113
(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
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  --
(According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
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  --
(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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  --

(Possibly Related Articles in Doctor's Guide)
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  --

(in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
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1 PubMed article for C10orf113 gene:
(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)
(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 387638 HGNC: 31447 AceView: C10orf113 Ensembl:ENSG00000204683 euGenes: HUgn387638
ECgene: C10orf113 H-InvDB: C10orf113
(According to HUGE)
About This Section

  --
(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

  --
(Available from WIS Yeda, Salk, Tufts)
About This Section

  --
(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section



Products for C10orf113:
 TaqMan ® Gene Expression Assays
 TaqMan ® Genotyping Assays
  Free SNP selection tool



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  Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for C10orf113-related products

 Millipore Custom Antibody & Bulk Services
 Millipore Preclinical / Clinical Development Services
 Millipore Immunoassay Services
 Millipore Target Screening & Profiling Services


 Predesigned and custom siRNAs for C10orf113 Browse antibodies at Sigma-Aldrich
 Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
 Lentivirus-delivered shRNAs for C10orf113 Browse small molecules at Sigma-Aldrich
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 Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
 Search Novus for antibodies for C10orf113

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