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Aliases for C10orf113 Gene

Aliases for C10orf113 Gene

  • Chromosome 10 Open Reading Frame 113 2 3 5
  • Putative Uncharacterized Protein C10orf113 3
  • BA165O3.1 3

External Ids for C10orf113 Gene

Previous GeneCards Identifiers for C10orf113 Gene

  • GC10M021418
  • GC10M021455
  • GC10M021414

Summaries for C10orf113 Gene

GeneCards Summary for C10orf113 Gene

C10orf113 (Chromosome 10 Open Reading Frame 113) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C10orf113 Gene

Genomics for C10orf113 Gene

Regulatory Elements for C10orf113 Gene

Enhancers for C10orf113 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10F021191 0.2 ENCODE 11.4 -45.2 -45158 0.2 JUN GATA3 CTBP1 FOSL2 FOS TCF7L2 RFX1 HLF CEBPB KLF4 C10orf113 NEBL ENSG00000228860
GH10F021166 0.2 ENCODE 11.2 -20.3 -20263 0.0 BCOR HDGF ATF1 CBX3 ESRRA ZMYM3 ZNF175 BACH1 UBTF ADNP C10orf113 RNU6-15P NEBL-AS1
GH10F021167 0.4 ENCODE 11.2 -20.5 -20517 0.4 BCOR HDGF ATF1 CBX3 ESRRA ZNF175 BACH1 UBTF FEZF1 ZIC2 AMD1P1 C10orf113 DNAJC1 RNU6-15P NEBL-AS1
GH10F021183 0.6 ENCODE 11 -37.9 -37904 2.9 BCOR PKNOX1 JUN ZMYM3 PTRF ZNF644 RARA ZNF316 GATA3 ZNF26 C10orf113 NEBL ENSG00000228860
GH10F021194 0.9 ENCODE 10.9 -48.0 -48017 1.0 STAT1 CBX3 CEBPB DPF2 NR3C1 EP300 RFX5 GATA3 ATF3 CBX5 C10orf113 ENSG00000228860 NEBL
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C10orf113 on UCSC Golden Path with GeneCards custom track

Genomic Location for C10orf113 Gene

Chromosome:
10
Start:
21,125,763 bp from pter
End:
21,146,559 bp from pter
Size:
20,797 bases
Orientation:
Minus strand

Genomic View for C10orf113 Gene

Genes around C10orf113 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C10orf113 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C10orf113 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C10orf113 Gene

Proteins for C10orf113 Gene

  • Protein details for C10orf113 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5VZT2-CJ113_HUMAN
    Recommended name:
    Putative uncharacterized protein C10orf113
    Protein Accession:
    Q5VZT2
    Secondary Accessions:
    • B9EIM9
    • E9PRX7

    Protein attributes for C10orf113 Gene

    Size:
    155 amino acids
    Molecular mass:
    17689 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAI40745.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAH70812.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for C10orf113 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C10orf113 Gene

Post-translational modifications for C10orf113 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C10orf113 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C10orf113 Gene

Domains & Families for C10orf113 Gene

Protein Domains for C10orf113 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C10orf113: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C10orf113 Gene

Function for C10orf113 Gene

Phenotypes for C10orf113 Gene

GenomeRNAi human phenotypes for C10orf113:
genes like me logo Genes that share phenotypes with C10orf113: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C10orf113 Gene

Localization for C10orf113 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C10orf113 Gene COMPARTMENTS Subcellular localization image for C10orf113 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C10orf113 Gene

Pathways & Interactions for C10orf113 Gene

SuperPathways for C10orf113 Gene

No Data Available

Interacting Proteins for C10orf113 Gene

Gene Ontology (GO) - Biological Process for C10orf113 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C10orf113 Gene

Transcripts for C10orf113 Gene

mRNA/cDNA for C10orf113 Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C10orf113 Gene

Chromosome 10 open reading frame 113:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C10orf113 Gene

No ASD Table

Relevant External Links for C10orf113 Gene

GeneLoc Exon Structure for
C10orf113
ECgene alternative splicing isoforms for
C10orf113

Expression for C10orf113 Gene

mRNA expression in normal human tissues for C10orf113 Gene

mRNA differential expression in normal tissues according to GTEx for C10orf113 Gene

This gene is overexpressed in Testis (x11.3) and Skin - Not Sun Exposed (Suprapubic) (x4.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C10orf113 Gene



NURSA nuclear receptor signaling pathways regulating expression of C10orf113 Gene:

C10orf113

SOURCE GeneReport for Unigene cluster for C10orf113 Gene:

Hs.664110
genes like me logo Genes that share expression patterns with C10orf113: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C10orf113 Gene

Orthologs for C10orf113 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C10orf113 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C10H10orf113 34
  • 99.14 (n)
C10orf113 35
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C2H10orf113 34
  • 87.5 (n)
cow
(Bos Taurus)
Mammalia C13H10orf113 34
  • 79.22 (n)
Species where no ortholog for C10orf113 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C10orf113 Gene

ENSEMBL:
Gene Tree for C10orf113 (if available)
TreeFam:
Gene Tree for C10orf113 (if available)

Paralogs for C10orf113 Gene

No data available for Paralogs for C10orf113 Gene

Variants for C10orf113 Gene

Sequence variations from dbSNP and Humsavar for C10orf113 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs10828194 -- 21,125,372(+) GTTTC(A/C)GGTTT intron-variant
rs10828195 -- 21,129,834(+) AGAAA(C/G)GAAAG intron-variant
rs10828196 -- 21,130,342(+) CAGAT(A/C)CAGCA intron-variant
rs10828197 -- 21,137,001(+) TGGCA(C/T)AGCAT intron-variant
rs10828198 -- 21,140,999(+) AATAA(C/T)GGAAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C10orf113 Gene

Variant ID Type Subtype PubMed ID
esv3331302 CNV insertion 20981092
nsv1119787 CNV deletion 24896259
nsv831806 CNV gain 17160897

Variation tolerance for C10orf113 Gene

Residual Variation Intolerance Score: 90.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.52; 88.84% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C10orf113 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C10orf113

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C10orf113 Gene

Disorders for C10orf113 Gene

Relevant External Links for C10orf113

Genetic Association Database (GAD)
C10orf113
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C10orf113

No disorders were found for C10orf113 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C10orf113 Gene

Publications for C10orf113 Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4 64
  2. A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity. (PMID: 24785509) Barnett G.C. … West C.M. (Radiother Oncol 2014) 3 64
  3. GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. (PMID: 23535730) Pharoah P.D. … Sellers T.A. (Nat. Genet. 2013) 3 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for C10orf113 Gene

Sources for C10orf113 Gene

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