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Aliases for C10orf111 Gene

Aliases for C10orf111 Gene

  • Chromosome 10 Open Reading Frame 111 2 3 5
  • Uncharacterized Protein C10orf111 3
  • BA455B2.4 3

External Ids for C10orf111 Gene

Previous GeneCards Identifiers for C10orf111 Gene

  • GC10M015142
  • GC10M015177
  • GC10M015047

Summaries for C10orf111 Gene

GeneCards Summary for C10orf111 Gene

C10orf111 (Chromosome 10 Open Reading Frame 111) is a Protein Coding gene.

Additional gene information for C10orf111 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C10orf111 Gene

Genomics for C10orf111 Gene

Regulatory Elements for C10orf111 Gene

Enhancers for C10orf111 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10H014647 1.8 FANTOM5 Ensembl ENCODE dbSUPER 13.4 +448.7 448678 3 HDGF PKNOX1 TBL1XR1 BMI1 BATF RFX5 SCRT2 ZNF143 ZNF207 ATF7 FAM107B C10orf111 HSPA14 CDNF DCLRE1C RPP38 LOC105376429 GC10M014524
GH10H015122 1.1 FANTOM5 ENCODE 16.9 -26.5 -26469 1 HDGF PKNOX1 MAX EBF1 BATF RELA GATA3 POLR2A ZNF143 FOS ACBD7 C10orf111 RPP38 GAPDHP45 DCLRE1CP1 OLAH GC10P015124 GC10P015108
GH10H014601 1.7 FANTOM5 ENCODE dbSUPER 10 +493.7 493718 4 HDGF PKNOX1 SIN3A FEZF1 YBX1 ZNF2 ZNF302 FOS SP3 MXD4 LOC105376429 GAPDHP45 FAM107B CDNF HSPA14 C10orf111 GC10M014524
GH10H015083 1.1 Ensembl ENCODE 12.5 +12.7 12721 1 TBP PKNOX1 FOXA2 NFIB DMAP1 RAD21 RFX5 ZNF350 RCOR1 CREM C10orf111 DCLRE1C ACBD7 RPP38 PIR44298 DCLRE1CP1
GH10H015096 1.1 ENCODE 12.1 -0.7 -679 3 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 ZNF207 SP3 MXD4 RPP38 HSPA14 C10orf111 ACBD7 LOC105376431
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C10orf111 on UCSC Golden Path with GeneCards custom track

Promoters for C10orf111 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000024893 -182 2200 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 ZNF207 SP3 MXD4

Genomic Location for C10orf111 Gene

Chromosome:
10
Start:
15,095,385 bp from pter
End:
15,097,319 bp from pter
Size:
1,935 bases
Orientation:
Minus strand

Genomic View for C10orf111 Gene

Genes around C10orf111 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C10orf111 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C10orf111 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C10orf111 Gene

Proteins for C10orf111 Gene

  • Protein details for C10orf111 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N326-CJ111_HUMAN
    Recommended name:
    Uncharacterized protein C10orf111
    Protein Accession:
    Q8N326
    Secondary Accessions:
    • B2RAC4

    Protein attributes for C10orf111 Gene

    Size:
    155 amino acids
    Molecular mass:
    17766 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C10orf111 Gene

Post-translational modifications for C10orf111 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C10orf111 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for C10orf111 Gene

Domains & Families for C10orf111 Gene

Protein Domains for C10orf111 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C10orf111: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C10orf111 Gene

Function for C10orf111 Gene

genes like me logo Genes that share phenotypes with C10orf111: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C10orf111
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C10orf111 Gene

Localization for C10orf111 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C10orf111 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C10orf111 gene
Compartment Confidence
nucleus 2

Gene Ontology (GO) - Cellular Components for C10orf111 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C10orf111: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for C10orf111 Gene

Pathways & Interactions for C10orf111 Gene

SuperPathways for C10orf111 Gene

No Data Available

Interacting Proteins for C10orf111 Gene

Selected Interacting proteins: Q8N326-CJ111_HUMAN for C10orf111 Gene via UniProtKB

Symbol External ID(s) Details
SEC22A

Gene Ontology (GO) - Biological Process for C10orf111 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C10orf111 Gene

Drugs & Compounds for C10orf111 Gene

No Compound Related Data Available

Transcripts for C10orf111 Gene

mRNA/cDNA for C10orf111 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(7) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C10orf111 Gene

Chromosome 10 open reading frame 111:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C10orf111
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for C10orf111 Gene

No ASD Table

Relevant External Links for C10orf111 Gene

GeneLoc Exon Structure for
C10orf111
ECgene alternative splicing isoforms for
C10orf111

Expression for C10orf111 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C10orf111 Gene

mRNA differential expression in normal tissues according to GTEx for C10orf111 Gene

This gene is overexpressed in Testis (x5.6) and Brain - Cerebellar Hemisphere (x4.1).

NURSA nuclear receptor signaling pathways regulating expression of C10orf111 Gene:

C10orf111

SOURCE GeneReport for Unigene cluster for C10orf111 Gene:

Hs.567777

Evidence on tissue expression from TISSUES for C10orf111 Gene

  • Nervous system(4.2)
genes like me logo Genes that share expression patterns with C10orf111: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C10orf111 Gene

Orthologs for C10orf111 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C10orf111 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C10orf111 34
  • 97 (a)
OneToOne
Species where no ortholog for C10orf111 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C10orf111 Gene

ENSEMBL:
Gene Tree for C10orf111 (if available)
TreeFam:
Gene Tree for C10orf111 (if available)

Paralogs for C10orf111 Gene

No data available for Paralogs for C10orf111 Gene

Variants for C10orf111 Gene

Sequence variations from dbSNP and Humsavar for C10orf111 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs1000339820 -- 15,098,515(+) CCTCG(C/T)CAGCC intron-variant, upstream-variant-2KB
rs1001050133 -- 15,096,250(+) GCTGG(A/C)TGGAG upstream-variant-2KB, utr-variant-3-prime
rs1001609458 -- 15,097,538(+) GTTGC(A/G)TGGCC intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs1002235080 -- 15,095,883(+) TAATC(C/T)TTCTA upstream-variant-2KB, utr-variant-3-prime
rs1002341531 -- 15,097,031(+) GGACG(A/G)TCCAA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C10orf111 Gene

Variant ID Type Subtype PubMed ID
nsv831794 CNV loss 17160897

Variation tolerance for C10orf111 Gene

Residual Variation Intolerance Score: 71.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.76; 66.54% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C10orf111 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C10orf111

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C10orf111 Gene

Disorders for C10orf111 Gene

Relevant External Links for C10orf111

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C10orf111

No disorders were found for C10orf111 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C10orf111 Gene

Publications for C10orf111 Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 3 4 60
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4 60

Products for C10orf111 Gene

Sources for C10orf111 Gene

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