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Aliases &
Descriptions
for C10orf10
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases |
|---|
| DEPP 1, 2 | | FIG 2, 3 | | OTTHUMP00000019496 2 |
| | | Descriptions |
|---|
| Decidual protein induced by progesterone 2, 3 | | Fasting-induced gene protein 3 | | chromosome 10 open reading frame 10 2 | | fasting induced 2 | | fasting-induced protein 2 |
|
| |
Search outside databases for aliases for C10orf10 genePrevious GC identifer: GC10M044755 |
Summaries
for C10orf10(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| EntrezGene summary for C10orf10:
The expression of this gene is induced by fasting as well as by progesterone. The protein encoded
by this gene contains a t-synaptosome-associated protein receptor (SNARE) coiled-coil homology
domain and a peroxisomal targeting signal. Production of the encoded protein leads to
phosphorylation and activation of the transcription factor ELK1. [provided by RefSeq]
Gene Wiki entry for C10orf10 |
Genomic Location
for C10orf10
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences)
About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
 Transcription factor binding sites upstream to the C10orf10 gene 
Entrez Gene cytogenetic band: 10q11.21 Ensembl cytogenetic band: 10q11.21 HGNC cytogenetic band: 10q11.21C10orf10 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10M044791:
(about GC identifiers)
Start:
|
44,791,715 bp from pter |
End:
|
44,794,336 bp from pter |
Size:
|
2,622 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000010.9 NT_033985.6
| Proteins
for C10orf10
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: DEPP_HUMAN, Q9NTK1 (See
protein sequence)Recommended Name: Protein DEPP Size: 212 amino acids; 23406 Da
Developmental stage: High levels in first trimester deciduas. Higher levels in the endometria
during secretory phase than the proliferative phase, especially after the mid-secretory phase
Sequence caution: Sequence=CAI13066.1; Type=Erroneous gene model prediction;
Secondary accessions: O94997 Q5T735 Q76MX8REFSEQ proteins: NP_008952.1
ENSEMBL proteins: ENSP00000298295
Human Recombinant Proteins  OriGene Purified Recombinant Human Protein: C10orf10
1 Gene Ontology (GO) cellular component term (links to tree view): About this table
Antibodies for C10orf10:
Assays for C10orf10: | Protein
Domains/
Families
for C10orf10(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q9NTK1 | Gene Function
for C10orf10
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_007021
 Applied Biosystems Silencer® siRNAs for C10orf10
 Sigma-Aldrich siRNA for C10orf10
Sigma-Aldrich shRNA for C10orf10
Explore Sigma-Aldrich super-pooled esiRNAs
OriGene GFP tagged cDNA clone in CMV expression vector: NM_007021
Myc/DDK tagged cDNA clone in CMV expression vector: NM_007021
untagged cDNA clones in CMV expression vector (see all 2): NM_007021
Primers:  Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
OriGene genome-wide validated SYBR primer pairs: NM_007021
UniProtKB/Swiss-Prot: DEPP_HUMAN, Q9NTK1Induction: By progesterone, testosterone and, to a much lower extent, estrogen1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for 8430408G22Rik):
| Pathways & Interactions
for C10orf10
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
5 Interacting proteins for C10orf10 (Q9NTK12) via UniProtKB, MINT, and/or STRINGAbout this table
|
Drugs & Compounds
for C10orf10(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for C10orf10
|
Transcripts
for C10orf10(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene,
Expression Assays from Applied Biosystems)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_007021
Sigma-Aldrich siRNA for C10orf10
Sigma-Aldrich shRNA for C10orf10
Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer® siRNAs: NM_007021 REFSEQ mRNAs for C10orf10 gene: NM_007021.3
Applied Biosystems TaqMan ® Gene Expression Assays: NM_007021
OriGene GFP tagged cDNA clone in CMV expression vector: NM_007021
Myc/DDK tagged cDNA clone in CMV expression vector: NM_007021
untagged cDNA clones in CMV expression vector (see all 2): NM_007021
Additional cDNA sequence: AB022718.1 AB025244.1 AK002191.1 AK098476.1 AK300839.1 AK312496.1 AL136653.1 BC011402.1 CR591726.1 CR592377.1 CR592827.1 CR614092.1 CR616425.1 CR617524.1 CR618606.1 CR623526.1 CR624673.1 24/27 DOTS entries (see all 27
): DT.40260675 DT.100856347 DT.95139113 DT.121228485 DT.100720213 DT.121228387 DT.100856357 DT.121228377 DT.97808897 DT.100051879 DT.121228410 DT.121228327 DT.121228232 DT.121228319 DT.121228322 DT.121228487 DT.100059701 DT.100831109 DT.121228235 DT.121228237 DT.121228246 DT.121228355 DT.121228380 DT.121228466 24/442 AceView cDNA sequences (see all 442
):BP342315 CR592827 AI288275 AA148923 AI282593 BQ890469 BM680464 CB068831 BQ549348 CB135912 BF475463 CR592377 CB216881 BX397682 AI269372 CR623526 CA390725 BX361324 CR624673 BX366111 BM707740 BP341866 CR614092 BM924040
 highest scoring ESTs for C10orf10:AB022718 AA452987 AB025244 AK002191 AK098476 AL136653 AL523800 AL531656 AL540343 AL540541 Unigene Cluster for C10orf10: Chromosome 10 open reading frame 10 Hs.93675 [show with all ESTs]Unigene Representative Sequence: AB022718
GeneLoc Exon Structure
1 Ensembl transcript including schematic representation: ENST00000298295
|
Expression
for C10orf10
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| C10orf10 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for C10orf10
1 / 2 / 3 5 probe-sets matching C10orf10 gene Data from
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: GTCAGGGTCC
SOURCE GeneReport for Unigene cluster: Hs.93675
Expression variation in blood from EXPOLDB for C10orf10 UniProtKB/Swiss-Prot: DEPP_HUMAN, Q9NTK1Tissue specificity: Expressed in various tissues, including pancreas, placenta, ovary, testis and
kidney |
Orthologs
for C10orf10
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for C10orf10 gene from 5 species
About this table Species with no ortholog for C10orf10
ENSEMBL Gene Tree for C10orf10 | Paralogs
for C10orf10(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| -- |
SNPs/Variants
for C10orf10(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
| -- |
Disorders & Mutations
for C10orf10
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 611309
|
Medical News
for C10orf10(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for C10orf10 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 10/14 PubMed articles for C10orf10 gene (see all 14
):- A novel protein Depp, which is induced by progesterone in human endometrial stromal cells activates Elk-1 transcription factor. (PubMed id 16123073)1, 3, 4 Watanabe H.... Fujita J. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)3, 4 Gerhard D.S....Malek J. (2004)
- The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)3, 4 Deloukas P.... Rogers J. (2004)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)3, 4 Wiemann S.... Poustka A. (2001)
- Isolation of arterial-specific genes by subtractive hybridization reveals molecular heterogeneity among arterial endothelial cells. (PubMed id 15977181)1, 3 Shin D. and Anderson D.J. (2005)
- The LIFEdb database in 2006. (PubMed id 16381901)3 Mehrle A....Wiemann S. (2006)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)3 Kimura K.... Sugano S. (2006)
- A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)3 Lim J....Zoghbi H.Y. (2006)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)3 Rual J.F....Vidal M. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)3 Ota T....Sugano S. (2004)
|
Search for C10orf10
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C10orf10
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing C10orf10
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C10orf10(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| About This Section
| --
| Services
for C10orf10(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section
| 
Products for C10orf10:
|
GeneCards Homepage - Last full update: 1 Jul 2009
Incremental update: 13 Oct 2009
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