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BZW2 Gene

protein-coding   GIFtS: 53
GCID: GC07P016652

Basic Leucine Zipper And W2 Domains 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Basic Leucine Zipper And W2 Domains 21 2
MST0172
MSTP0172
Basic Leucine Zipper And W2 Domain-Containing Protein 22

External Ids:    HGNC: 188081   Entrez Gene: 289692   Ensembl: ENSG000001362617   UniProtKB: Q9Y6E23   

Export aliases for BZW2 gene to outside databases

Previous GC identifers: GC07P016330 GC07P016430 GC07P016458 GC07P016572


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for BZW2 Gene:
BZW2 (basic leucine zipper and W2 domains 2) is a protein-coding gene. Diseases associated with BZW2 include alzheimer's disease, and hiv-1. An important paralog of this gene is BZW1.

UniProtKB/Swiss-Prot: BZW2_HUMAN, Q9Y6E2
Function: May be involved in neuronal differentiation (By similarity)

Gene Wiki entry for BZW2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000007.14  NT_007819.18  NC_018918.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the BZW2 gene promoter:
         HOXA9B   HOXA9   USF1   AP-1   USF2   USF-1:USF-2   USF-1   Meis-1a   MRF-2   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 4): BZW2 promoter sequence
   Search Chromatin IP Primers for BZW2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BZW2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p21.1   Ensembl cytogenetic band:  7p21.1   HGNC cytogenetic band: 7p21.3

BZW2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BZW2 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P016652:  view genomic region     (about GC identifiers)

Start:
16,685,756 bp from pter      End:
16,746,148 bp from pter
Size:
60,393 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 16,738,882-16,799,268     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: BZW2_HUMAN, Q9Y6E2 (See protein sequence)
Recommended Name: Basic leucine zipper and W2 domain-containing protein 2  
Size: 419 amino acids; 48162 Da
Sequence caution: Sequence=AAI07758.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential
poly-A sequence;
Secondary accessions: A4D123 Q3B779 Q9H3F7

Explore the universe of human proteins at neXtProt for BZW2: NX_Q9Y6E2

Explore proteomics data for BZW2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys117, Lys232
  • Modification sites at PhosphoSitePlus

  • See BZW2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001153239.1  NP_054757.1  

    ENSEMBL proteins: 
     ENSP00000403481   ENSP00000258761   ENSP00000406395   ENSP00000389183   ENSP00000385577  
     ENSP00000412750   ENSP00000415924   ENSP00000416531   ENSP00000384617   ENSP00000397249  
     ENSP00000411715  

    BZW2 Human Recombinant Protein Products:

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    Cloud-Clone Corp. CLIAs for BZW2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR016021 MIF4-like_typ_1/2/3
     IPR003307 W2_domain
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q9Y6E2

    ProtoNet protein and cluster: Q9Y6E2

    1 Blocks protein domain: IPB003307 eIF4-gamma/eIF5/eIF2-epsilon

    UniProtKB/Swiss-Prot: BZW2_HUMAN, Q9Y6E2
    Similarity: Belongs to the BZW family
    Similarity: Contains 1 W2 domain


    BZW2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BZW2_HUMAN, Q9Y6E2
    Function: May be involved in neuronal differentiation (By similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488binding ----
    GO:0005515protein binding ----
         
    BZW2 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Bzw2 (no phenotypes)

    BZW2 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for BZW2
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for BZW2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for BZW2

    miRNA
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    miRTarBase miRNAs that target BZW2:
    hsa-mir-191-5p (MIRT045798), hsa-let-7b-5p (MIRT032241)

    Block miRNA regulation of human, mouse, rat BZW2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate BZW2 (see all 13):
    hsa-miR-98 hsa-let-7d hsa-let-7c hsa-let-7i hsa-miR-218 hsa-let-7g hsa-let-7e hsa-miR-135b
    SwitchGear 3'UTR luciferase reporter plasmidBZW2 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Predesigned siRNA for gene silencing in human, mouse, rat BZW2

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 2): BZW2 (NM_014038)
    Sino Biological Human cDNA Clone for BZW2
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BZW2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BZW2

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for BZW2 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BZW2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus2
    cytoskeleton1
    cytosol1
    mitochondrion1
    peroxisome1
    plasma membrane1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for BZW2
    Interactions:

        Search GeneGlobe Interaction Network for BZW2

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    Selected Interacting proteins for BZW2 (Q9Y6E22, 3 ENSP000002587614) via UniProtKB, MINT, STRING, and/or I2D (see all 588)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BZW1Q7L1Q62, 3, ENSP000003943164MINT-7945693 I2D: score=2 STRING: ENSP00000394316
    GSK3BP498412, 3MINT-8256943 I2D: score=2 
    PSTPIP1O435863, ENSP000003689144I2D: score=2 STRING: ENSP00000368914
    ELAVL1Q157172, ENSP000003852694MINT-7945693 STRING: ENSP00000385269
    SNW1Q135732, ENSP000002615314MINT-7945693 STRING: ENSP00000261531
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007399nervous system development IEA--
    GO:0030154cell differentiation IEA--

    BZW2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for BZW2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for BZW2 gene (2 alternative transcripts): 
    NM_001159767.1  NM_014038.2  

    Unigene Cluster for BZW2:

    Basic leucine zipper and W2 domains 2
    Hs.487635  [show with all ESTs]
    Unigene Representative Sequence: NM_001159767
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000415365(uc011jxx.1 uc003sto.1) ENST00000258761(uc003stj.2)
    ENST00000432311 ENST00000437745 ENST00000436868 ENST00000405202 ENST00000480517(uc003stn.1)
    ENST00000446596 ENST00000438834 ENST00000430000 ENST00000407633 ENST00000433922(uc003stl.2 uc003stm.2)
    ENST00000452975
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat BZW2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate BZW2 (see all 13):
    hsa-miR-98 hsa-let-7d hsa-let-7c hsa-let-7i hsa-miR-218 hsa-let-7g hsa-let-7e hsa-miR-135b
    SwitchGear 3'UTR luciferase reporter plasmidBZW2 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for BZW2
    Predesigned siRNA for gene silencing in human, mouse, rat BZW2
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    OriGene clones in human, mouse for BZW2 (see all 12)
    OriGene ORF clones in mouse, rat for BZW2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): BZW2 (NM_014038)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BZW2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BZW2
    Primer
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    OriGene qPCR primer pairs and template standards for BZW2
    OriGene qSTAR qPCR primer pairs in human, mouse for BZW2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat BZW2
      QuantiTect SYBR Green Assays in human, mouse, rat BZW2
      QuantiFast Probe-based Assays in human, mouse, rat BZW2

    Additional mRNA sequence: 

    AF083246.1 AF110323.1 AK001218.1 AK001260.1 AK297496.1 BC001570.1 BC003056.1 BC008453.1 
    BC009597.1 BC017794.1 BC051898.1 BC107757.1 NR_027624.1 

    Selected DOTS entries (see all 34):

    DT.97795544  DT.216172  DT.92396013  DT.100878987  DT.92328785  DT.100878978  DT.92458742  DT.100878972 
    DT.92458760  DT.92458749  DT.100878976  DT.95251126  DT.100878988  DT.100879006  DT.121051984  DT.121052020 
    DT.100878992  DT.121051997  DT.121052028  DT.121052119  DT.92396953  DT.95251196  DT.100760865  DT.100878980 

    Selected AceView cDNA sequences (see all 578):

    CR618505 BM972716 BX438875 CA336841 AW664315 CA487539 CB117350 CB131845 
    BX358533 BG572851 CA395233 CR619763 CR603998 BX403810 H18960 CR620073 
    CR613733 AK001260 BM791327 BX396413 BX335263 BM823741 BX401845 AA206893 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for BZW2 (see all 15)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c · 9d ^ 10 ^ 11a · 11b · 11c ^ 12a · 12b ^ 13a · 13b ^ 14 ^ 15a · 15b ^
    SP1:        -     -     -     -                                   -                             -                                                               
    SP2:              -     -     -                                   -                             -                                                               
    SP3:                                                              -     -                       -                                                               
    SP4:        -     -     -     -                                   -     -                       -                                                               
    SP5:                          -                                   -                             -                                                               

    ExUns: 16
    SP1:      
    SP2:      
    SP3:      
    SP4:      
    SP5:      


    ECgene alternative splicing isoforms for BZW2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    BZW2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATGTGATTT
    BZW2 Expression
    About this image

    BZW2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    BZW2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.487635
        Custom PCR Arrays for BZW2
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    QuantiFast Probe-based Assays in human, mouse, rat BZW2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BZW2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for BZW2 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Bzw21 , 5 basic leucine zipper and W2 domains 21, 5 91.73(n)1
    99.05(a)1
      12 (16.42 cM)5
    669121  NM_025840.31  NP_080116.21 
     360918465 
    chicken
    (Gallus gallus)
    Aves BZW21 basic leucine zipper and W2 domains 2 84.15(n)
    94.12(a)
      420594  NM_001006358.1  NP_001006358.1 
    lizard
    (Anolis carolinensis)
    Reptilia BZW26
    basic leucine zipper and W2 domains 2
    91(a)
    1 ↔ 1
    6(27505693-27531544)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia bzw21 basic leucine zipper and W2 domains 2 79(n)
    89.95(a)
      100493753  XM_002933293.1  XP_002933339.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc555802 similar to basic leucine zipper and W2 domains 2 76.25(n)   393892  BC048052.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta exba6
    extra bases
    50(a)
    1 → many
    3R(1421086-1426858)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G652201 AT1G65220 46.4(n)
    34(a)
      842829  NM_105195.2  NP_564845.1 
    rice
    (Oryza sativa)
    Liliopsida Os11g04140001 Os11g0414000 47.48(n)
    33.5(a)
      4350359  NM_001074292.1  NP_001067760.1 


    ENSEMBL Gene Tree for BZW2 (if available)
    TreeFam Gene Tree for BZW2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for BZW2 gene
    BZW12  
    2 SIMAP similar genes for BZW2 using alignment to 11 protein entries:     BZW2_HUMAN (see all proteins):
    Nbla10236    BZW1

    BZW2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for BZW2
    PGOHUM00000237862


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for BZW2 (see all 1301)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs615903061,2
    C--16580201(+) AAAAA-/A/    
       AAAAA
    TACAA
    3 -- int11NA 2
    rs1888151331,2
    --16687443(+) TTACCA/GGCAGA 3 -- int10--------
    rs797618911,2
    C,F--16687458(+) TACACA/GTAATT 3 -- int12Minor allele frequency- G:0.05NA 122
    rs1455444821,2
    --16687500(+) GTGCCA/GAATCT 3 -- int10--------
    rs176201101,2
    C,F,H--16687542(+) TGTCTC/TACTGG 3 -- int128Minor allele frequency- N:0.00NA EA NS WA 2860
    rs1399279261,2
    C--16687544(+) TCTCA-/CTGG  
     GGTTGTC
    AGTTC
    3 -- int10--------
    rs2007249921,2
    --16687547(+) CACTG-/GGG   
       TTGTC
    AGTTC
    3 -- int10--------
    rs1477574901,2
    --16687570(+) GGATAC/GCAGCT 3 -- int10--------
    rs1838505011,2
    --16687624(+) TAGTGC/TTCTCT 3 -- int10--------
    rs1879779421,2
    --16687626(+) GTGCTC/GTCTGA 3 -- int10--------

    HapMap Linkage Disequilibrium report for BZW2 (16685756 - 16746148 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for BZW2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2665677CNV Deletion23128226
    esv25168CNV Loss19812545
    nsv517565CNV Loss19592680
    nsv437016CNV Loss16327808
    nsv887760CNV Gain21882294
    nsv830912CNV Gain17160897
    nsv887759CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    3 diseases for BZW2:    
    About MalaCards
    alzheimer's disease    hiv-1    neuronitis


    BZW2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): BZW2
    Human Genome Epidemiology (HuGE) Navigator: BZW2 (4 documents)

    Export disorders for BZW2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for BZW2 gene, integrated from 10 sources (see all 39):
    (articles sorted by number of sources associating them with BZW2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2, 3 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (Science 2003)
    8. Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. (PubMed id 23535033)1 Sherva R....Green R.C. (amp 2014)
    9. VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (PLoS ONE 2013)
    10. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 28969 HGNC: 18808 AceView: BZW2 Ensembl:ENSG00000136261 euGenes: HUgn28969
    ECgene: BZW2 H-InvDB: BZW2

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for BZW2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for BZW2 gene:
    Search GeneIP for patents involving BZW2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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