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BZW1 Gene

protein-coding   GIFtS: 52
GCID: GC02P201675

Basic Leucine Zipper And W2 Domains 1

  See BZW1-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Basic Leucine Zipper And W2 Domains 11 2     Basic Leucine-Zipper Protein BZAP452
BZAP452 3     Putative Protein Product Of Nbla102362
Nbla102362     KIAA00053
Basic Leucine Zipper And W2 Domain-Containing Protein 12     Protein Orf3

External Ids:    HGNC: 183801   Entrez Gene: 96892   Ensembl: ENSG000000821537   UniProtKB: Q7L1Q63   

Export aliases for BZW1 gene to outside databases

Previous GC identifers: GC02P199893 GC02P200400 GC02P201640 GC02P201879 GC02P201501 GC02P201384 GC02P193528


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for BZW1 Gene:
BZW1 (basic leucine zipper and W2 domains 1) is a protein-coding gene. Diseases associated with BZW1 include phlebotomus fever. An important paralog of this gene is BZW2.

UniProtKB/Swiss-Prot: BZW1_HUMAN, Q7L1Q6
Function: Enhances histone H4 gene transcription but does not seem to bind DNA directly

Gene Wiki entry for BZW1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NC_018913.2  NT_005403.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the BZW1 gene promoter:
         TBP   AML1a   C/EBPalpha   HNF-1A   Nkx6-1   HOXA5   HNF-1   c-Myb   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBZW1 promoter sequence
   Search Chromatin IP Primers for BZW1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BZW1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q33   Ensembl cytogenetic band:  2q33.1   HGNC cytogenetic band: 2q33

BZW1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BZW1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P201675:  view genomic region     (about GC identifiers)

Start:
201,675,317 bp from pter      End:
201,688,569 bp from pter
Size:
13,253 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: BZW1_HUMAN, Q7L1Q6 (See protein sequence)
Recommended Name: Basic leucine zipper and W2 domain-containing protein 1  
Size: 419 amino acids; 48043 Da
Developmental stage: Expressed in day 3 embryo
Sequence caution: Sequence=BAA02795.2; Type=Erroneous initiation;
Secondary accessions: B4DLZ8 B4DWF7 Q14281 Q15394 Q9BUY0
Alternative splicing: 4 isoforms:  Q7L1Q6-1   Q7L1Q6-2   Q7L1Q6-3   Q7L1Q6-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for BZW1: NX_Q7L1Q6

Explore proteomics data for BZW1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys5, Lys60, Lys140, Lys191, Lys197, Lys223, Lys231, Lys239, Lys259, Lys272,
                                 Lys399
  • Modification sites at PhosphoSitePlus

  • See BZW1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001193996.1  NP_001193997.1  NP_001193998.1  NP_055485.2  

    ENSEMBL proteins: 
     ENSP00000412072   ENSP00000390766   ENSP00000387086   ENSP00000386474   ENSP00000386837  
     ENSP00000394316   ENSP00000393587   ENSP00000407268   ENSP00000395673  

    BZW1 Human Recombinant Protein Products:

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    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for BZW1

     
    Search eBioscience for Proteins for BZW1 

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    Cloud-Clone Corp. ELISAs for BZW1
    Cloud-Clone Corp. CLIAs for BZW1
    Search eBioscience for ELISAs for BZW1 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR016021 MIF4-like_typ_1/2/3
     IPR003307 W2_domain
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q7L1Q6

    ProtoNet protein and cluster: Q7L1Q6

    1 Blocks protein domain: IPB003307 eIF4-gamma/eIF5/eIF2-epsilon

    UniProtKB/Swiss-Prot: BZW1_HUMAN, Q7L1Q6
    Similarity: Belongs to the BZW family
    Similarity: Contains 1 W2 domain


    Find genes that share domains with BZW1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BZW1_HUMAN, Q7L1Q6
    Function: Enhances histone H4 gene transcription but does not seem to bind DNA directly

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488binding ----
    GO:0005515protein binding ----
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with BZW1           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for BZW1:
     Elongated cells  Increased cell number in S 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for BZW1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for BZW1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for BZW1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for BZW1

    miRNA
    Products:
        
    miRTarBase miRNAs that target BZW1:
    hsa-mir-1260b (MIRT052785), hsa-mir-25-3p (MIRT050244), hsa-mir-16-5p (MIRT031563)

    Block miRNA regulation of human, mouse, rat BZW1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate BZW1 (see all 32):
    hsa-miR-1321 hsa-let-7d hsa-miR-1197 hsa-miR-938 hsa-miR-3074-3p hsa-miR-3142 hsa-let-7g hsa-let-7a
    SwitchGear 3'UTR luciferase reporter plasmidBZW1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for BZW1
    Predesigned siRNA for gene silencing in human, mouse, rat BZW1

    Gene Editing
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    Clone
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    OriGene ORF clones in mouse, rat for BZW1
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    GenScript: all cDNA clones in your preferred vector: BZW1 (NM_014670)
    Sino Biological Human cDNA Clone for BZW1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BZW1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BZW1

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for BZW1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BZW1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion3
    cytosol2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA10942595

    Find genes that share ontologies with BZW1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for BZW1
    Interactions:

        Search GeneGlobe Interaction Network for BZW1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    Selected Interacting proteins for BZW1 (Q7L1Q61, 2, 3 ENSP000003943164) via UniProtKB, MINT, STRING, and/or I2D (see all 787)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CDC5LQ994592, 3, ENSP000003605324MINT-7945693 MINT-7947479 I2D: score=1 STRING: ENSP00000360532
    BZW2Q9Y6E22, 3, ENSP000002587614MINT-7945693 I2D: score=2 STRING: ENSP00000258761
    DCTN1Q142032, 3, ENSP000003547914MINT-7945693 I2D: score=2 STRING: ENSP00000354791
    PSTPIP1O435861, 3, ENSP000003689144EBI-1046727,EBI-1050964 I2D: score=2 STRING: ENSP00000368914
    SNW1Q135732, ENSP000002615314MINT-7945693 MINT-7947479 STRING: ENSP00000261531
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--

    Find genes that share ontologies with BZW1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for BZW1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for BZW1 gene (4 alternative transcripts): 
    NM_001207067.1  NM_001207068.1  NM_001207069.1  NM_014670.3  

    Unigene Cluster for BZW1:

    Basic leucine zipper and W2 domains 1
    Hs.355983  [show with all ESTs]
    Unigene Representative Sequence: NM_001207067
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000450637 ENST00000452206(uc002uwb.1) ENST00000410110 ENST00000409600(uc002uwc.3 uc021vus.1 uc010zhg.2)
    ENST00000464483 ENST00000460660 ENST00000409226 ENST00000452790 ENST00000447069
    ENST00000419090 ENST00000463310 ENST00000491576 ENST00000359893
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat BZW1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate BZW1 (see all 32):
    hsa-miR-1321 hsa-let-7d hsa-miR-1197 hsa-miR-938 hsa-miR-3074-3p hsa-miR-3142 hsa-let-7g hsa-let-7a
    SwitchGear 3'UTR luciferase reporter plasmidBZW1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for BZW1
    Predesigned siRNA for gene silencing in human, mouse, rat BZW1
    Clone
    Products:
         
    OriGene clones in human, mouse for BZW1 (see all 8)
    OriGene ORF clones in mouse, rat for BZW1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: BZW1 (NM_014670)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BZW1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BZW1
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for BZW1
    OriGene qSTAR qPCR primer pairs in human, mouse for BZW1
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat BZW1
      QuantiTect SYBR Green Assays in human, mouse, rat BZW1
      QuantiFast Probe-based Assays in human, mouse, rat BZW1

    Additional mRNA sequence: 

    AB074176.1 AK096489.1 AK223245.1 AK297227.1 AK301511.1 AL833518.1 BC001804.1 BC026303.1 
    D13630.1 Z70221.1 

    Selected DOTS entries (see all 45):

    DT.452770  DT.121036434  DT.95086936  DT.100861228  DT.100684646  DT.91776641  DT.91776621  DT.91994227 
    DT.91776645  DT.95086932  DT.121036423  DT.100684640  DT.97864520  DT.120843344  DT.75145562  DT.92005498 
    DT.91776623  DT.99953343  DT.121036427  DT.121036394  DT.95150213  DT.100684648  DT.91776633  DT.121036413 

    Selected AceView cDNA sequences (see all 928):

    AA404395 AI701310 AI688953 AA548192 AA112284 BU175166 AL833518 AW262270 
    AL542256 BU178709 AI583732 N64475 AI333488 BM460069 AA317098 BQ228623 
    AW963627 CA395033 AI433139 CB136075 NM_014670 BQ436848 AI424200 BG498598 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for BZW1 (see all 11)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10 ^ 11a · 11b · 11c ^ 12a · 12b ^ 13 ^ 14 ^ 15
    SP1:                          -     -     -                             -                                                         
    SP2:        -     -     -     -     -     -                             -                                                         
    SP3:                    -     -     -     -                             -                                                         
    SP4:                          -     -     -                             -                             -                           
    SP5:                                -     -                             -                                                         


    ECgene alternative splicing isoforms for BZW1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    BZW1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CACAGGCAAA
    BZW1 Expression
    About this image


    BZW1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 17) fully expand
     
     Brain (Nervous System)
             Cerebral Cortex
     
     Inner Cell Mass (Early Embryonic Tissues)
             Inner Cell Mass Cells Inner Cell Mass
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Colon (Gastrointestinal Tract)
     
     Uterus (Reproductive System)
    BZW1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    BZW1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.355983
        Custom PCR Arrays for BZW1
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for BZW1
    OriGene qSTAR qPCR primer pairs in human, mouse for BZW1
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat BZW1
    QuantiTect SYBR Green Assays in human, mouse, rat BZW1
    QuantiFast Probe-based Assays in human, mouse, rat BZW1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BZW1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for BZW1 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Bzw11 , 5 basic leucine zipper and W2 domains 11, 5 92.6(n)1
    100(a)1
      1 (29.09 cM)5
    668821  NM_025824.31  NP_080100.11 
     583931365 
    chicken
    (Gallus gallus)
    Aves BZW11 basic leucine zipper and W2 domains 1 86.49(n)
    97.36(a)
      424073  NM_001006516.1  NP_001006516.1 
    lizard
    (Anolis carolinensis)
    Reptilia BZW16
    basic leucine zipper and W2 domains 1
    83(a)
    1 ↔ 1
    1(118078194-118096840)
    African clawed frog
    (Xenopus laevis)
    Amphibia bzw1-prov2 basic leucine zipper and W2 domains 1 84.28(n)    BC041729.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BC044401.12   -- 75.37(n)    BC044401.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta exba1 extra bases 56.11(n)
    51.49(a)
      40680  NM_169078.2  NP_730962.1 


    ENSEMBL Gene Tree for BZW1 (if available)
    TreeFam Gene Tree for BZW1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for BZW1 gene
    BZW22  
    2 SIMAP similar genes for BZW1 using alignment to 7 protein entries:     BZW1_HUMAN (see all proteins):
    Nbla10236    BZW2

    Find genes that share paralogs with BZW1           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for BZW1
    PGOHUM00000237731


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for BZW1 (see all 256)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1896477581,2
    --201674276(+) TTTGCC/TACATA 2 -- us2k10--------
    rs729270511,2
    C--201674289(+) CCACAA/TTGATG 2 -- us2k13Minor allele frequency- T:0.04NA EA 242
    rs1811299731,2
    --201674447(+) AGAAAA/GGGGAT 2 -- us2k10--------
    rs1457842681,2
    C--201674496(+) TAGGGG/TTAATA 2 -- us2k10--------
    rs1489516741,2
    --201674553(+) AACGTA/GGCAAA 2 -- us2k10--------
    rs730570971,2
    C,F--201674608(+) ATCTCT/CACTGG 2 -- us2k13Minor allele frequency- C:0.07WA CSA 122
    rs729270521,2
    C,F--201674818(+) ACAGGG/ATAGTT 2 -- us2k12Minor allele frequency- A:0.09NA EA 240
    rs1470413351,2
    --201674896(+) AGTTAC/TCATTT 2 -- us2k10--------
    rs1382577451,2
    C--201674938(+) TTCAGA/GTGTGA 3 -- us2k10--------
    rs1429008571,2
    C--201674984(+) CTGACA/GGTGTT 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for BZW1 (201675317 - 201688569 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for BZW1: --
    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing BZW1
    DNA2.0 Custom Variant and Variant Library Synthesis for BZW1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for BZW1:    
    About MalaCards
    phlebotomus fever

    1 disease from the University of Copenhagen DISEASES database for BZW1:
    Phlebotomus fever

    Find genes that share disorders with BZW1           About GenesLikeMe


    Export disorders for BZW1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for BZW1 gene, integrated from 10 sources (see all 36):
    (articles sorted by number of sources associating them with BZW1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Purification and functional analysis of a novel leucine- zipper/nucleotide-fold protein, BZAP45, stimulating cell cycle regulated histone H4 gene transcription. (PubMed id 11524015)1, 2, 3, 9 Mitra P.... van Wijnen A.J. (Biochemistry 2001)
    2. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (Nat. Biotechnol. 2006)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    4. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W.... Wilson R.K. (Nature 2005)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. A physical and transcript map based upon refinement of the critical interval for PPH1, a gene for familial primary pulmonary hypertension. The International PPH Consortium. (PubMed id 10964520)1, 3 Machado R.D....Nichols W.C. (Genomics 2000)
    8. Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. (PubMed id 7584026)1, 2 Nomura N.... Tabata S. (DNA Res. 1994)
    9. BZW1, a novel proliferation regulator that promotes growth of salivary muocepodermoid carcinoma. (PubMed id 19446954)1, 9 Li S....Situ Z. (Cancer Lett. 2009)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9689 HGNC: 18380 AceView: BZW1 Ensembl:ENSG00000082153 euGenes: HUgn9689
    ECgene: BZW1 H-InvDB: BZW1

    (According to HUGE)
    About This Section

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    HUGE: KIAA0005

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for BZW1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for BZW1 gene:
    Search GeneIP for patents involving BZW1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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