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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

BYSL Gene

protein-coding   GIFtS: 55
GCID: GC06P041888

bystin-like
 Explore 14 diseases affiliated with
BYSL via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for BYSL    

Aliases
for BYSL gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Bystin-Like1
BYSTIN2
By The Ribosomal Protein S6 Gene, Drosophila, Homolog-Like2
Bystin1

External Ids:    HGNC: 11571   Entrez Gene: 7052   Ensembl: ENSG000001125787   OMIM: 6038715   UniProtKB: Q138953   

Export aliases for BYSL gene to outside databases

Previous GC identifers: GC06P041891 GC06P041936 GC06P041996 GC06P041607


Summaries
for BYSL gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for BYSL:
Bystin is expressed as a 2-kb major transcript and a 3.6-kb minor transcript in SNG-M cells and in human trophoblastic
teratocarcinoma HT-H cells. Protein binding assays determined that bystin binds directly to trophinin and tastin, and
that binding is enhanced when cytokeratins 8 and 18 are present. Immunocytochemistry of HT-H cells showed that bystin
colocalizes with trophinin, tastin, and the cytokeratins, suggesting that these molecules form a complex in
trophectoderm cells at the time of implantation. Using immunohistochemistry it was determined that trophinin and
bystin are found in the placenta from the sixth week of pregnancy. Both proteins were localized in the cytoplasm of
the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface.
After week 10, the levels of trophinin, tastin, and bystin decreased and then disappeared from placental villi.
(provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: BYST_HUMAN, Q13895
Function: Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required
for trophinin-dependent regulation of cell adhesion during implantation of human embryos

Gene Wiki entry for BYSL


Genomic Views
for BYSL gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the BYSL gene promoter:
         NF-1/L   NF-1   AML1a   SRF (504 AA)   GCNF   MyoD   E47   GCNF-1   Hand1   GCNF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: BYSL promoter sequence
   Search SABiosciences Chromatin IP Primers for BYSL

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BYSL


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.1   Ensembl cytogenetic band:  6p21.1   HGNC cytogenetic band: 6p21.1

BYSL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BYSL gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P041888:  view genomic region     (about GC identifiers)

Start:
 41,888,926 bp from pter      End:
 41,900,784 bp from pter
Size:
 11,859 bases      Orientation:
 plus strand

Proteins
for BYSL gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: BYST_HUMAN, Q13895 (See protein sequence)
Recommended Name: Bystin  
Size: 437 amino acids; 49601 Da
Subunit: Binds trophinin, tastin and cytokeratins
Subcellular location: Cytoplasm. Nucleus, nucleolus. Note=Associated with 40S ribosomal subunits
Miscellaneous: HeLa cells lacking BYSL show a delay in the processing of the 18S rRNA component of the 40S ribosomal
subunit. HT-H cells lacking BYSL show trophinin-independent signaling through ERBB4
Sequence caution: Sequence=AAC16603.2; Type=Erroneous initiation;
Secondary accessions: Q6P5W4 Q86W44 Q96IP8

Explore the universe of human proteins at neXtProt for BYSL: NX_Q13895

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q13895

    • BYSL Protein expression data from MOPED and PaxDb:    About this image 
    BYSL Protein Expression
    REFSEQ proteins: NP_004044.3  
    ENSEMBL proteins: 
     ENSP00000230340   ENSP00000417813   ENSP00000362087  

    Human Recombinant Protein Products for BYSL: 
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    OriGene Custom Protein Services for BYSL 
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    Novus Biologicals BYSL Protein
    Novus Biologicals BYSL Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for BYSL

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IEA--
    GO:0043231intracellular membrane-bounded organelle IDA--

    BYSL for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for BYSL

    Protein Domains /
    Families
    for BYSL gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    BYSL for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR007955 Bystin

    Graphical View of Domain Structure for InterPro Entry Q13895

    ProtoNet protein and cluster: Q13895

    1 Blocks protein family: IPB007955 Bystin

    UniProtKB/Swiss-Prot: BYST_HUMAN, Q13895
    Similarity: Belongs to the bystin family


    Function
    for BYSL gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BYST_HUMAN, Q13895
    Function: Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required
    for trophinin-dependent regulation of cell adhesion during implantation of human embryos

         Genatlas biochemistry entry for BYSL:
    bystin,cytoplasmic protein binding directly to trophinin and tastin which mediate the homophilic adhesion between
    trophoblast and endometrial epithelial cells,implicated in embryo implantations process

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI9560222
         
    BYSL for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for BYSL:
     Increased cell death HMECs cel 

         1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Bysl):
     mortality/aging 

    BYSL for phenotypes           About GeneDecksing

    Animal Models:
         Mouse knock-out Bysltm1Mfu for BYSL
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for BYSL 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BYSL
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate BYSL:
    hsa-miR-4323 hsa-miR-1910
    SwitchGear 3'UTR luciferase reporter plasmid: BYSL 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BYSL (see all 7)
    OriGene shRNA RFP: BYSL
    OriGene siRNA: BYSL
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    Sirion Biotech Custom design and validation of potent shRNA sequences against BYSL 

    Gene Editing
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    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BYSL (see all 3)
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    Cell Line
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    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BYSL


    Pathways & Interactions
    for BYSL gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for BYSL

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/245 Interacting proteins for BYSL (Q138951, 2, 3 ENSP000002303404) via UniProtKB, MINT, STRING, and/or I2D (see all 245)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=2 
    HIST1H4BP628053I2D: score=2 
    HIST1H4CP628053I2D: score=2 
    HIST1H4DP628053I2D: score=2 
    HIST1H4EP628053I2D: score=2 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007155cell adhesion TAS9560222
    GO:0007565female pregnancy TAS9560222
    GO:0042254ribosome biogenesis IEA--

    BYSL for ontologies           About GeneDecksing



    Drugs & Compounds
    for BYSL gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    BYSL for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for BYSL
    1 Novoseek chemical compound relationship for BYSL gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tyrosine 11.1 2 17495530 (1), 9560222 (1)

    Search CenterWatch for drugs/clinical trials and news about BYSL / BYST 

    Transcripts
    for BYSL gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for BYSL gene: 
    NM_004053.3  

    Unigene Cluster for BYSL:

    Bystin-like
    Hs.106880  [show with all ESTs]
    Unigene Representative Sequence: AK095253
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000230340(uc003orl.3) ENST00000494032 ENST00000489290 ENST00000475702
    ENST00000372996

    miRNA
    Products:             		 OriGene 3'-UTR Clone: BYSL
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BYSL
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate BYSL:
    hsa-miR-4323 hsa-miR-1910
    SwitchGear 3'UTR luciferase reporter plasmid: BYSL 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BYSL (see all 7)
    OriGene shRNA RFP: BYSL
    OriGene siRNA: BYSL
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    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BYSL
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BYSL

    Additional cDNA sequence: 

    AK095253.1 AK314147.1 BC007340.2 BC050645.1 BC062627.1 L36720.2 

    8 DOTS entries:

    DT.414559  DT.95115597  DT.100794499  DT.113635  DT.100030969  DT.100030970  DT.95115601  DT.86855253 

    24/306 AceView cDNA sequences (see all 306):

    BM811352 BM797263 CR604574 BC050645 CB156176 BQ672556 BM995668 BM756679 
    BQ674528 CR590222 BQ680096 BQ675159 CR590918 BQ687590 BU191035 BM767304 
    BQ216046 NM_004053 BM770349 AW328164 BQ642074 BM741219 BU738866 BQ045345 

    GeneLoc Exon Structure


    Expression
    for BYSL gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    BYSL expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CTGAAAATTG
    BYSL Expression
    About this image

    BYSL expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    HSF-1 (UC01) (Embryonic Stem Cell)Early Embryo, Inner Cell Mass
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See BYSL Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for BYSL

    SOURCE GeneReport for Unigene cluster: Hs.106880

    UniProtKB/Swiss-Prot: BYST_HUMAN, Q13895
    Tissue specificity: Found in the placenta from the sixth week of pregnancy. Was localized in the cytoplasm of the
    syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After
    week 10, the level decreased and then disappeared from placental villi

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    In Situ
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    Orthologs
    for BYSL gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for BYSL gene from 10/34 species (see all 34)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Bysl1 , 5 bystin-like1, 5 85.63(n)1
    90.83(a)1    		   17 (23.63 cM)5
    534141  NM_016859.31  NP_058555.31 
     475993315 
    chicken
    (Gallus gallus)    		 Aves BYSL1 bystin-like 73.11(n)
    76.81(a)    		   419927  XM_418047.3  XP_418047.3 
    lizard
    (Anolis carolinensis)    		 Reptilia BYSL6
    		 --
    		 75(a)
    		 1 ↔ 1
    		 4(119264652-119276908)
    African clawed frog
    (Xenopus laevis)    		 Amphibia 480237162   -- 75.99(n)    48023716 
    zebrafish
    (Danio rerio)    		 Actinopterygii BC053134.12   -- 78.71(n)   394081  BC053134.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta bys1 , 3 by S61 63(a)3
    57.6(n)1
    54.16(a)1    		   1 7C23
    317011  NM_078519.21  NP_511074.11 
    worm
    (Caenorhabditis elegans)    		 Secernentea F57B9.53
    byn-11    		 Protein BYN-11 59(a)3
    56.02(n)1
    52.83(a)1    		   III(7003761-7007409)3
    1759681  NM_066109.21  NP_498510.11 
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes ENP1(YBR247C)4
    ENP11    		 Protein associated with U3 and U14 snoRNAs, required more4
    Enp1p1    		 48.38(n)1
    41.02(a)1    		   2(714455-713004)4
    8525491, 4  NP_009806.31  NP_009806.14 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT1G316601 putative bystin 54.28(n)
    45.89(a)    		   840053  NM_102901.3  NP_174447.2 
    rice
    (Oryza sativa)    		 Liliopsida Os09g03524001 hypothetical protein 53.48(n)
    47.57(a)    		   4346824  NM_001069493.1  NP_001062958.1 


    ENSEMBL Gene Tree for BYSL (if available)
    TreeFam Gene Tree for BYSL (if available) 

    Paralogs
    for BYSL gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for BYSL gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/283 NCBI SNPs in BYSL are shown (see all 283)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 6 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1829750181,2
    		--41887172(+) TATTAA/CGGTAG 2 -- us2k1 int10--------
    rs800327531,2
    		F--41887210(+) TACTCT/CATCAG 2 -- int1 us2k11Minor allele frequency- C:0.03WA 118
    rs2006925941,2
    		--41887215(+) ATCAG-/AAAAAA 2 -- int1 us2k10--------
    rs1435464501,2
    		--41887510(+) TTCTTC/TAAAAA 2 -- us2k1 int10--------
    rs1883569511,2
    		--41887745(+) GCCTCC/TGGATT 2 -- us2k1 int10--------
    rs1929907701,2
    		--41887799(+) AATGTA/TCTGGG 2 -- us2k1 int10--------
    rs1467885761,2
    		--41888098(+) AGAGCA/TGGCGA 2 -- us2k1 int10--------
    rs786772391,2
    		C--41888417(+) ACAGGA/CGAATC 2 -- us2k1 int10--------
    rs1848011111,2
    		--41888531(+) CAAAAA/C/GAAAAA 2 -- us2k1 int10--------
    rs1880744381,2
    		--41888540(+) AACCTC/TTGCTT 2 -- int1 us2k10--------

    HapMap Linkage Disequilibrium report for BYSL (41888926 - 41900784 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for BYSL: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BYSL
    DNA2.0 Custom Variant and Variant Library Synthesis for BYSL

    Disorders / Diseases
    for BYSL gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    BYSL for disorders           About GeneDecksing

    OMIM gene information: 603871    OMIM disorders: --

    14 diseases for BYSL:    About MalaCards
    teratocarcinoma    ectopic pregnancy    hypopyon    chronic lymphocytic leukemia
    lymphocytic leukemia    hepatocellular carcinoma    leukemia    prostate cancer
    ischemia    ataxia    hypoxia    prostatitis
    carcinoma    malaria

    2 Novoseek disease relationships for BYSL gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    shock 17.2 3 18218589 (1), 17381424 (1), 17109495 (1)
    cancer 2.26 6 17381424 (2), 19687802 (1), 17917702 (1), 16245277 (1) (see all 5)

    Human Genome Epidemiology (HuGE) Navigator: BYSL (3 documents)

    Export disorders for BYSL gene to outside databases

    Publications
    for BYSL gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for BYSL gene, integrated from 9 sources (see all 51):
    (articles sorted by number of sources associating them with BYSL)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Bystin in human cancer cells: intracellular localization and function in ribosome biogenesis. (PubMed id 17381424)1, 2, 3, 9 Miyoshi M.... Nadano D. (2007)
    2. A cytoplasmic protein, bystin, interacts with trophinin, tastin, and cytokeratin and may be involved in trophinin-mediated cell adhesion between trophoblast and endometrial epithelial cells. (PubMed id 9560222)1, 2, 9 Suzuki N.... Fukuda M.N. (1998)
    3. Trophoblast cell activation by trophinin ligation is implicated in human embryo implantation. (PubMed id 17360433)1, 2, 9 Sugihara K.... Fukuda M.N. (2007)
    4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Assignment1 of the bystin gene BYSL to human chromosome band 6p21.1 by in situ hybridization. (PubMed id 9925933)1, 3 Pack S.D....Fukuda M.N. (1998)
    7. The role of bystin in embryo implantation and in ribosomal biogenesis. (PubMed id 17917702)1, 9 Fukuda M.N....Nadano D. (2008)
    8. Expression of trophinin, tastin, and bystin by trophoblast and endometrial cells in human placenta. (PubMed id 10026108)1, 9 Suzuki N....Fukuda M.N. (1999)
    9. Implantation-dependent expression of trophinin by maternal fallopian tube epithelia during tubal pregnancies: possible role of human chorionic gonadotrophin on ectopic pregnancy. (PubMed id 14633596)1, 9 Nakayama J....Fukuda M.N. (2003)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)

    External Searches for BYSL gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Genome Databases showing BYSL gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 705 HGNC: 1157 AceView: BYSL Ensembl:ENSG00000112578 euGenes: HUgn705
    ECgene: BYSL H-InvDB: BYSL

    Other Databases showing BYSL gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing BYSL gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for BYSL Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for BYSL Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for BYSL gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for BYSL gene:
    Search GeneIP for patents involving BYSL

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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