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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

BVES Gene

protein-coding   GIFtS: 52
GCID: GC06M105594

Blood Vessel Epicardial Substance

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Blood Vessel Epicardial Substance1 2     POPDC12 3
Popeye Domain Containing 11 2     HBVES2
Popeye Domain-Containing Protein 12 3     hBVES3
Popeye Protein 12 3     H5
POP12 3     

External Ids:    HGNC: 11521   Entrez Gene: 111492   Ensembl: ENSG000001122767   OMIM: 6045775   UniProtKB: Q8NE793   

Export aliases for BVES gene to outside databases

Previous GC identifers: GC06M105408 GC06M105571 GC06M105652 GC06M102987


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for BVES Gene:
This gene encodes a member of the POP family of proteins containing three putative transmembrane domains. This
gene is expressed in cardiac and skeletal muscle and may play an important role in development of these tissues.
The mouse ortholog may be involved in the regeneration of adult skeletal muscle and may act as a cell adhesion
molecule in coronary vasculogenesis. Three transcript variants encoding the same protein have been found for this
gene. (provided by RefSeq, Dec 2010)

GeneCards Summary for BVES Gene: 
BVES (blood vessel epicardial substance) is a protein-coding gene. Diseases associated with BVES include colon cancer, and lung cancer. GO annotations related to this gene include structural molecule activity. An important paralog of this gene is POPDC3.

UniProtKB/Swiss-Prot: POPD1_HUMAN, Q8NE79
Function: Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in
the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells.
Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its
interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family
GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation
of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and
in the regulation of cell spreading

Gene Wiki entry for BVES (Blood vessel epicardial substance) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.2  NT_025741.15  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for BVES
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBVES promoter sequence
   Search SABiosciences Chromatin IP Primers for BVES

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BVES


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q21   Ensembl cytogenetic band:  6q21   HGNC cytogenetic band: 6q21

BVES Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BVES gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M105594:  view genomic region     (about GC identifiers)

Start:
105,544,697 bp from pter      End:
105,585,049 bp from pter
Size:
40,353 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: POPD1_HUMAN, Q8NE79 (See protein sequence)
Recommended Name: Blood vessel epicardial substance  
Size: 360 amino acids; 41451 Da
Subunit: Homodimer. Homodimerization requires the C-terminus cytoplasmic region. Interacts (via the C-terminus
cytoplasmic tail) with TJP1. Interacts (via the C-terminus cytoplasmic tail) with ARHGEF25/GEFT (via the DH
domain). Interacts (via the C-terminus cytoplasmic tail) with VAMP3 (By similarity)
Subcellular location: Lateral cell membrane. Cell junction, tight junction. Membrane; Multi-pass membrane protein
(Potential). Note=Colocalizes with VAMP3 at the cell-cell contact in cardiac and skeletal muscle (By similarity).
Its movement from the cytoplasm to membrane is an early event occurring concurrently with cell-cell contact.
Colocalizes in epithelial cells with OCLN and TJP1 in an apical-lateral position within the z axis. Detected at
cell-cell contact but never observed at the free surface of epithelial cells
Secondary accessions: A8K1R4 E1P5D8 Q5T550 Q5T551 Q8IWC6 Q9HBV0 Q9UNG6

Explore the universe of human proteins at neXtProt for BVES: NX_Q8NE79

Explore proteomics data for BVES at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8NE79

  • BVES Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    BVES Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001186492.1  NP_009004.2  NP_671488.1  

    ENSEMBL proteins: 
     ENSP00000313172   ENSP00000337259   ENSP00000397310  

    Human Recombinant Protein Products for BVES: 
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    Cloud-Clone Corp. Proteins for BVES 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane ISS--
    GO:0005923tight junction IDA16188940
    GO:0016020membrane ----
    GO:0016021integral to membrane NAS10441744
    GO:0016328lateral plasma membrane IDA16188940

    BVES for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR018490 cNMP-bd-like
     IPR014710 RmlC-like_jellyroll
     IPR006916 Popeye_prot

    Graphical View of Domain Structure for InterPro Entry Q8NE79

    ProtoNet protein and cluster: Q8NE79

    UniProtKB/Swiss-Prot: POPD1_HUMAN, Q8NE79
    Similarity: Belongs to the popeye family


    BVES for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: POPD1_HUMAN, Q8NE79
    Function: Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in
    the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells.
    Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its
    interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family
    GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation
    of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and
    in the regulation of cell spreading

         Genatlas biochemistry entry for BVES:
    mouse Bves homolog,expressed in developing and adult heart and skeletal muscle

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005198structural molecule activity IDA16188940
    GO:0005515protein binding ----
         
    BVES for ontologies           About GeneDecksing


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Bves):
     cardiovascular system  homeostasis/metabolism  muscle 

    BVES for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for BVES 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for BVES 
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    miRNA
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    8/65 QIAGEN miScript miRNA Assays for microRNAs that regulate BVES (see all 65):
    hsa-miR-548j hsa-miR-579 hsa-miR-607 hsa-miR-520e hsa-miR-106a hsa-miR-485-3p hsa-miR-3622b-3p hsa-miR-93
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BVES


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BVES

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for BVES (ENSP000003131724) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARHGEF25ENSP000003355604STRING: ENSP00000335560
    About this table

    Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001921positive regulation of receptor recycling ISS--
    GO:0007517muscle organ development NAS10441744
    GO:0008360regulation of cell shape ISS--
    GO:0016192vesicle-mediated transport ISS--
    GO:0032314regulation of Rac GTPase activity ISS--

    BVES for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for BVES (POPD1)

    Search CenterWatch for drugs/clinical trials and news about BVES / POPD1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for BVES gene (3 alternative transcripts): 
    NM_001199563.1  NM_007073.4  NM_147147.3  

    Unigene Cluster for BVES:

    Blood vessel epicardial substance
    Hs.221660  [show with all ESTs]
    Unigene Representative Sequence: NM_001199563
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000314641(uc003pqw.3 uc003pqx.3 uc003pqy.3) ENST00000336775
    ENST00000446408
    miRNA
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    8/65 QIAGEN miScript miRNA Assays for microRNAs that regulate BVES (see all 65):
    hsa-miR-548j hsa-miR-579 hsa-miR-607 hsa-miR-520e hsa-miR-106a hsa-miR-485-3p hsa-miR-3622b-3p hsa-miR-93
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BVES
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BVES

    Additional mRNA sequence: 

    AF204172.1 AK289979.1 BC034425.1 BC040502.1 

    7 DOTS entries:

    DT.113629  DT.100010179  DT.99998002  DT.121384705  DT.97824488  DT.65288584  DT.40307457 

    24/59 AceView cDNA sequences (see all 59):

    NM_007073 AI014924 AI192695 AI392605 BC034425 AI694818 BQ000347 CA446644 
    BQ447484 AI680775 NM_147147 AA704071 AI141226 BI489708 N75833 AA310706 
    BF510301 N87979 AW182350 BF576342 BG676918 AI040044 BC040502 CB118860 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    BVES expression in normal human tissues (normalized intensities)      BVES embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGGATTTTAT
    BVES Expression
    About this image


    BVES expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/8 selected tissues (see all 8) fully expand
     
     Heart (Cardiovascular System)    fully expand to see all 3 entries
             Proepicardial Progenitor cells Proepicardium
             heart muscle ; myocytes   
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             vastus lateralis   
     
     Testis (Reproductive System)
             sperm   
     
     Umbilical Cord (Extraembryonic Tissues)
             Umbilical cord blood-derived mesenchymal stem cells
     
     Blood (Hematopoietic System)
             Umbilical cord blood-derived mesenchymal stem cells

    See BVES Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for BVES

    SOURCE GeneReport for Unigene cluster: Hs.221660

    UniProtKB/Swiss-Prot: POPD1_HUMAN, Q8NE79
    Tissue specificity: Expressed in epithelial cells (at protein level). Expressed in fetal and adult heart and
    skeletal muscle

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for BVES gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Bves1 , 5 blood vessel epicardial substance1, 5 85.1(n)1
    87.71(a)1
      10 (23.47 cM)5
    238281  NM_024285.21  NP_077247.11 
     453357625 
    chicken
    (Gallus gallus)
    Aves BVES1 blood vessel epicardial substance 75.96(n)
    77.18(a)
      408032  NM_001001299.2  NP_001001299.2 
    lizard
    (Anolis carolinensis)
    Reptilia BVES6
    Uncharacterized protein
    70(a)
    1 ↔ 1
    GL343430.1(576255-601627)
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3983232 popeye 1 protein 75.47(n)    AF461429.1 
    zebrafish
    (Danio rerio)
    Actinopterygii popdc11 popeye domain containing 1 65.36(n)
    69.28(a)
      415107  NM_001001847.1  NP_001001847.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta bves6
    bves
    22(a)
    1 → many
    X(20924990-20953418)


    ENSEMBL Gene Tree for BVES (if available)
    TreeFam Gene Tree for BVES (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for BVES gene
    POPDC32  POPDC22  
    2 SIMAP similar genes for BVES using alignment to 1 protein entry:     POPD1_HUMAN:
    POPDC2    POPDC3

    BVES for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/880 SNPs in BVES are shown (see all 880)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1396742501,2
    C--105544228(+) TCCATC/TCCAAT 3 -- ds50010--------
    rs1459777391,2
    C--105544288(+) ACTGT-/CCCCCC 3 -- ds50010--------
    rs1819576421,2
    --105544293(+) TCCCCC/GTCATC 3 -- ds50010--------
    rs1873386831,2
    --105544340(+) TTCATA/GTGACT 3 -- ds50010--------
    rs1446265091,2
    --105544345(+) GTGACC/TCCTCA 3 -- ds50010--------
    rs1478373151,2
    --105544372(+) GAAACC/TAGAAG 3 -- ds50010--------
    rs1398125921,2
    --105544433(+) CATCAA/GTAAAA 3 -- ds50010--------
    rs58788331,2
    C,F--105544498(+) GGCCA-/TTTTTT 3 -- ds50013Minor allele frequency- T:0.33NA CSA 6
    rs18902271,2
    C,F,A,H--105544803(+) GTTATC/TAATTT 3 -- ut3116Minor allele frequency- T:0.12MN NS EA NA 2082
    rs1452246681,2
    --105544902(+) CAAGTA/GTAACA 3 -- ut310--------

    HapMap Linkage Disequilibrium report for BVES (105544697 - 105585049 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/13 variations for BVES (see all 13):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2732533CNV Deletion23290073
    esv3772CNV Deletion18987735
    esv2614469CNV Deletion19546169
    esv993961CNV Deletion20482838
    esv1920969CNV Deletion18987734
    nsv886529CNV Loss21882294
    esv6261CNV Loss19470904
    nsv830754CNV Gain17160897
    dgv216e55CNV Gain17911159
    nsv7950CNV Gain18304495


    Human Gene Mutation Database (HGMD): BVES
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing BVES
    DNA2.0 Custom Variant and Variant Library Synthesis for BVES

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 604577    OMIM disorders: --

    3 diseases for BVES:    About MalaCards
    colon cancer    lung cancer    gastric cancer


    BVES for disorders           About GeneDecksing

    Genetic Association Database (GAD): BVES
    Human Genome Epidemiology (HuGE) Navigator: BVES (1 document)

    Export disorders for BVES gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for BVES gene, integrated from 9 sources (see all 28):
    (articles sorted by number of sources associating them with BVES)
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    1. Isolation and characterization of the novel popeye gene family expressed in skeletal muscle and heart. (PubMed id 10882522)1, 2, 3, 9 Andree B.... Brand T. (2000)
    2. Cloning and expression of hbves, a novel and highly conserved mRNA expressed in the developing and adult heart and skeletal muscle in the human. (PubMed id 10441744)1, 2, 3 Reese D.E. and Bader D.M. (1999)
    3. The role of height-associated loci identified in geno me wide association studies in the determination of pediatric stature. (PubMed id 20546612)1, 4 Zhao J....Grant S.F. (2010)
    4. Genome-wide association study identifies sequence var iants on 6q21 associated with age at menarche. (PubMed id 19448622)1, 4 Sulem P....Stefansson K. (2009)
    5. Many sequence variants affecting diversity of adult human height. (PubMed id 18391951)1, 4 Gudbjartsson D.F....Stefansson K. (2008)
    6. Bves modulates epithelial integrity through an interaction at the tight junction. (PubMed id 16188940)1, 2 Osler M.E....Bader D.M. (2005)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Abnormal expression of adhesion protein Bves is associ ated with gastric cancer progression and poor survival. (PubMed id 22109561)1 Luo D....Wang Y. (2012)
    9. Popeye domain containing proteins are essential for st ress-mediated modulation of cardiac pacemaking in mice. (PubMed id 22354168)1 Froese A....Brand T. (2012)
    10. BVES regulates EMT in human corneal and colon cancer cells and is silenced via promoter methylation in human colorectal carcinoma. (PubMed id 21911938)1 Williams C.S....Chang M.S. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 11149 HGNC: 1152 AceView: BVES Ensembl:ENSG00000112276 euGenes: HUgn11149
    ECgene: BVES H-InvDB: BVES

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for BVES Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for BVES gene:
    Search GeneIP for patents involving BVES

    GeneCards and IP:
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