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Aliases for BUD31 Gene

Aliases for BUD31 Gene

  • BUD31 Homolog (S. Cerevisiae) 2 3
  • Functional Spliceosome-Associated Protein 17 2 3
  • Protein G10 Homolog 3 4
  • Protein EDG-2 3 4
  • EDG2 3 4
  • G10 3 6
  • G10 Maternal Transcript Homolog (Xenopus Laevis) 2
  • G10 Maternal Transcript Homolog 3
  • Maternal G10 Transcript 3
  • BUD31 Homolog (Yeast) 2
  • Protein BUD31 Homolog 3
  • YCR063W 3
  • FSAP17 3
  • Edg-2 3
  • Cwc14 3

External Ids for BUD31 Gene

Previous GeneCards Identifiers for BUD31 Gene

  • GC07P098844
  • GC07P099006
  • GC07P093642

Summaries for BUD31 Gene

GeneCards Summary for BUD31 Gene

BUD31 (BUD31 Homolog (S. Cerevisiae)) is a Protein Coding gene. Among its related pathways are Nanog in Mammalian ESC Pluripotency and Actin Nucleation by ARP-WASP Complex. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BUD31 Gene

Genomics for BUD31 Gene

Regulatory Elements for BUD31 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for BUD31 Gene

Start:
99,408,641 bp from pter
End:
99,419,616 bp from pter
Size:
10,976 bases
Orientation:
Plus strand

Genomic View for BUD31 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for BUD31 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BUD31 Gene

Proteins for BUD31 Gene

  • Protein details for BUD31 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P41223-BUD31_HUMAN
    Recommended name:
    Protein BUD31 homolog
    Protein Accession:
    P41223
    Secondary Accessions:
    • A4D274
    • B7Z4S9
    • D6W5S6
    • Q6IB53
    • Q9UDV1

    Protein attributes for BUD31 Gene

    Size:
    144 amino acids
    Molecular mass:
    17000 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for BUD31 Gene

    Alternative splice isoforms for BUD31 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for BUD31 Gene

Proteomics data for BUD31 Gene at MOPED

Post-translational modifications for BUD31 Gene

  • Ubiquitination at Lys66
  • Modification sites at PhosphoSitePlus

Other Protein References for BUD31 Gene

No data available for DME Specific Peptides for BUD31 Gene

Domains for BUD31 Gene

Protein Domains for BUD31 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for BUD31 Gene

Graphical View of Domain Structure for InterPro Entry

P41223

UniProtKB/Swiss-Prot:

BUD31_HUMAN :
  • P41223
Family:
  • Belongs to the BUD31 (G10) family.
genes like me logo Genes that share domains with BUD31: view

No data available for Gene Families for BUD31 Gene

Function for BUD31 Gene

Gene Ontology (GO) - Molecular Function for BUD31 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003700 sequence-specific DNA binding transcription factor activity TAS 7841202
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with BUD31: view
genes like me logo Genes that share phenotypes with BUD31: view

Animal Model Products

CRISPR Products

miRNA for BUD31 Gene

miRTarBase miRNAs that target BUD31

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for BUD31

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for BUD31 Gene

Localization for BUD31 Gene

Subcellular locations from UniProtKB/Swiss-Prot for BUD31 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for BUD31 Gene COMPARTMENTS Subcellular localization image for BUD31 gene
Compartment Confidence
nucleus 4
extracellular 2
cytoskeleton 1
cytosol 1
golgi apparatus 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for BUD31 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus TAS 7841202
GO:0005681 spliceosomal complex IBA --
genes like me logo Genes that share ontologies with BUD31: view

Pathways for BUD31 Gene

genes like me logo Genes that share pathways with BUD31: view

Pathways by source for BUD31 Gene

1 KEGG pathway for BUD31 Gene

Gene Ontology (GO) - Biological Process for BUD31 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000398 mRNA splicing, via spliceosome IBA --
GO:0006357 regulation of transcription from RNA polymerase II promoter TAS 7841202
genes like me logo Genes that share ontologies with BUD31: view

Transcripts for BUD31 Gene

Unigene Clusters for BUD31 Gene

BUD31 homolog (S. cerevisiae):
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for BUD31

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for BUD31 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c
SP1: - - -
SP2: - - - -
SP3: - - - -
SP4: - -
SP5: -
SP6:

Relevant External Links for BUD31 Gene

GeneLoc Exon Structure for
BUD31
ECgene alternative splicing isoforms for
BUD31

Expression for BUD31 Gene

mRNA expression in normal human tissues for BUD31 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for BUD31 Gene

SOURCE GeneReport for Unigene cluster for BUD31 Gene Hs.380233

genes like me logo Genes that share expressions with BUD31: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for BUD31 Gene

Orthologs for BUD31 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for BUD31 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia BUD31 35
  • 100 (n)
  • 100 (a)
BUD31 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia BUD31 35
  • 93.52 (n)
  • 100 (a)
BUD31 36
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 36
  • 93 (a)
OneToMany
-- 36
  • 100 (a)
OneToMany
BUD31 35
  • 93.29 (n)
  • 100 (a)
mouse
(Mus musculus)
Mammalia Bud31 16
Bud31 36
  • 100 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia BUD31 36
  • 99 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia BUD31 36
  • 83 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Bud31 35
  • 89.58 (n)
  • 98.61 (a)
chicken
(Gallus gallus)
Aves BUD31 35
  • 81.94 (n)
  • 99.31 (a)
BUD31 36
  • 99 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia BUD31 36
  • 98 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia g10-prov 35
tropical clawed frog
(Silurana tropicalis)
Amphibia bud31 35
  • 79.17 (n)
  • 97.22 (a)
Str.6577 35
zebrafish
(Danio rerio)
Actinopterygii bud31 35
  • 78.01 (n)
  • 95.83 (a)
bud31 36
  • 96 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP002301 35
  • 74.54 (n)
  • 85.42 (a)
fruit fly
(Drosophila melanogaster)
Insecta l(1)10Bb 35
  • 75.23 (n)
  • 86.81 (a)
l(1)10Bb 36
  • 86 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea C07A9.2 35
  • 65.73 (n)
  • 69.72 (a)
C07A9.2 36
  • 67 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes BUD31 35
  • 56.25 (n)
  • 54.17 (a)
BUD31 36
  • 48 (a)
OneToOne
BUD31 38
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0C08800g 35
  • 58.33 (n)
  • 52.78 (a)
Alicante grape
(Vitis vinifera)
eudicotyledons Vvi.371 35
thale cress
(Arabidopsis thaliana)
eudicotyledons AT4G21110 35
  • 64.8 (n)
  • 65.73 (a)
barley
(Hordeum vulgare)
Liliopsida Hv.6375 35
corn
(Zea mays)
Liliopsida Zm.7011 35
rice
(Oryza sativa)
Liliopsida Os05g0446300 35
  • 64.57 (n)
  • 70.63 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU00417 35
  • 59.21 (n)
  • 53.15 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes cwf14 35
  • 55.71 (n)
  • 60.14 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.3886 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 84 (a)
OneToOne
Species with no ortholog for BUD31:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for BUD31 Gene

ENSEMBL:
Gene Tree for BUD31 (if available)
TreeFam:
Gene Tree for BUD31 (if available)

Paralogs for BUD31 Gene

Pseudogenes.org Pseudogenes for BUD31 Gene

genes like me logo Genes that share paralogs with BUD31: view

No data available for Paralogs for BUD31 Gene

Variants for BUD31 Gene

Sequence variations from dbSNP and Humsavar for BUD31 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs1053866 -- 99,411,091(+) AAGGA(A/G)AATGC utr-variant-5-prime
rs1053867 -- 99,411,108(+) TCAAA(A/C)GAAGC reference, synonymous-codon
rs1053892 -- 99,411,162(+) TGGAT(C/G)AATTA missense, reference
rs3764815 -- 99,411,346(-) ATTTT(A/C)GGGCA intron-variant
rs6943920 -- 99,410,792(+) CAATT(A/C)TAATG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for BUD31 Gene

Variant ID Type Subtype PubMed ID
nsv831069 CNV Loss 17160897
nsv5864 CNV Insertion 18451855

Relevant External Links for BUD31 Gene

HapMap Linkage Disequilibrium report
BUD31

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BUD31 Gene

Disorders for BUD31 Gene

Relevant External Links for BUD31

Genetic Association Database (GAD)
BUD31
genes like me logo Genes that share disorders with BUD31: view

No data available for UniProtKB/Swiss-Prot for BUD31 Gene

Publications for BUD31 Gene

  1. Characterization of edg-2, a human homologue of the Xenopus maternal transcript G10 from endothelial cells. (PMID: 7841202) Hla T. … Maciag T. (Biochim. Biophys. Acta 1995) 2 3 4 23
  2. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3 4
  3. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3

Products for BUD31 Gene

Sources for BUD31 Gene

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