BUD31 Gene
protein-coding GIFtS: 53
GCID: GC07P099006
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|
BUD31 homolog (S. cerevisiae)(Previous name: BUD31 homolog (yeast) )
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Aliases
for BUD31 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| BUD31 Homolog (S. Cerevisiae)1 2 | | Protein EDG-22 3 | | EDG21 2 3 | | Protein G10 Homolog2 3 | | Cwc141 2 | | BUD31 Homolog (Yeast)1 | | EDG-21 2 | | Functional Spliceosome-Associated Protein 172 | | G101 2 | | G10 Maternal Transcript Homolog2 | | YCR063W1 2 | | Maternal G10 Transcript2 | | FSAP171 | | Protein BUD31 Homolog2 |
Export aliases for BUD31 gene to outside databasesPrevious GC identifers: GC07P098844 GC07P093642 |
Summaries
for BUD31 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for BUD31 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007933.15 NT_079595.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the BUD31 gene promoter:
HFH-3 E2F-3a E2F-4 E2F-5 RREB-1 E2F-2 c-Ets-1 GATA-2 E2F-1 E2F
Other transcription factors
Search SABiosciences Chromatin IP Primers for BUD31
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BUD31 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q22.1 Ensembl cytogenetic band: 7q22.1 HGNC cytogenetic band: 7q22.1BUD31 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P099006: view genomic region
(about GC identifiers)
Start:
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99,006,264 bp from pter |
End:
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99,017,239 bp from pter |
Size:
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10,976 bases |
Orientation:
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plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 98,366,375-98,377,013 |
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Proteins
for BUD31 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: BUD31_HUMAN, P41223 (See
protein sequence)Recommended Name: Protein BUD31 homolog Size: 144 amino acids; 17000 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: A4D274 D6W5S6 Q6IB53 Q9UDV1Explore the universe of human proteins at neXtProt for BUD31: NX_P41223
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P41223
BUD31 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_003901.2
ENSEMBL proteins: ENSP00000386023 ENSP00000416698 ENSP00000222969 ENSP00000395269 ENSP00000408269
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
BUD31 for ontologies About GeneDecksing
BUD31 Antibody Products:
Assay Products for BUD31: |
Protein
Domains /
Families
for BUD31 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
BUD31 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P41223ProtoNet protein and cluster: P41223 1 Blocks protein family: IPB001748 G10 protein
UniProtKB/Swiss-Prot: BUD31_HUMAN, P41223Similarity: Belongs to the BUD31 (G10) family |
Function
for BUD31 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BUD31 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BUD31
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: BUD31 (NM_003910) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BUD31 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BUD31 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BUD31 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003700 | sequence-specific DNA binding transcription factor activity |
TAS | 7841202 |
BUD31 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for BUD31:
|
Pathways & Interactions
for BUD31 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | mRNA Splicing - Major Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Kegg Pathway (Kegg details for BUD31):
BUD31 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BUD31
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/89 Interacting proteins for BUD31 (P412232, 3 ENSP000002229694) via UniProtKB, MINT, STRING, and/or I2D (see all 89)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006357 | regulation of transcription from RNA polymerase II promoter |
TAS | 7841202 |
BUD31 for ontologies About GeneDecksing
|
Drugs & Compounds
for BUD31 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for BUD31
Search CenterWatch for drugs/clinical trials and news about BUD31
|
Transcripts
for BUD31 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for BUD31 gene: NM_003910.3 Unigene Cluster for BUD31: BUD31 homolog (S. cerevisiae) Hs.380233 [show with all ESTs]Unigene Representative Sequence: BM9258529 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000403633(uc003uqf.3) ENST00000427499 ENST00000496696(uc011kiu.1)
ENST00000222969(uc011kiv.1 uc003uqg.4) ENST00000473447 ENST00000471813
ENST00000456893 ENST00000431419 ENST00000466798
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BUD31 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BUD31
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: BUD31 (NM_003910) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BUD31 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BUD31 |
Additional cDNA sequence: AK297784.1 AK316477.1 BC022821.1 BC104670.1 CR456951.1 23 DOTS entries: DT.92443205 DT.102837319 DT.100828634 DT.100828635 DT.100808868 DT.447787 DT.100775577 DT.102837314 DT.100031233 DT.100828639 DT.100828637 DT.119015 DT.121072433 DT.92443211 DT.40241182 DT.95073910 DT.121072264 DT.100676404 DT.100828627 DT.121072139 DT.121072325 DT.70100295 DT.95159547 24/416 AceView cDNA sequences (see all 416): BM680737 BM556099 BM826838 BQ446840 AA043512 CR589984 BI856054 BF513438 BE796031 BG708019 CB114404 AI818027 NM_003910 BM739680 AL557309 AW026279 CB142041 BU072511 AW575344 BU662501 CA311854 AL524503 BQ879589 BU181440
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for BUD31 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c |
|---|
|
| SP1: | | | | | | | | | - | | - | | | | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | | | | | | | - | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | - | | | | | | | | - | | - | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for BUD31
|
Expression
for BUD31 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| BUD31 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGGGAAAGAG
About this image
See BUD31 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for BUD31
SOURCE GeneReport for Unigene cluster: Hs.380233
SABiosciences Custom PCR Arrays for BUD31
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BUD31
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat BUD31 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BUD31 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BUD31 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BUD31 |
Orthologs
for BUD31 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for BUD31 gene from 10/39 species (see all 39) About this table
ENSEMBL Gene Tree for BUD31 (if available)
TreeFam Gene Tree for BUD31 (if available) |
Paralogs
for BUD31 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for BUD31 gene
BUD31 for paralogs About GeneDecksing
3 Pseudogenes.org Pseudogenes for BUD31
PGOHUM00000237434 PGOHUM00000249290 PGOHUM00000241857
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Genomic Variants
for BUD31 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for BUD31 (99006264 - 99017239 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for BUD31
1 CNV: 4548 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for BUD31 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
BUD31 for disorders About GeneDecksing
OMIM gene information: 603477
OMIM disorders: --
1  disease for BUD31: About MalaCardsmalaria
Export disorders for BUD31 gene to outside databases
|
Publications
for BUD31 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for BUD31 gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with BUD31) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of edg-2, a human homologue of the Xenopus maternal transcript G10 from endothelial cells. (PubMed id 7841202)1, 2, 3, 9 Hla T.... Maciag T. (1995)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
- The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- A catalogue of putative HIV-1 protease host cell subst rates. (PubMed id 22944692)1 Impens F....Gevaert K. (2012)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyc losome substrate. (PubMed id 21628590)1 Emanuele M.J....Elledge S.J. (2011)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
|
External Searches for BUD31 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing BUD31 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing BUD31 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing BUD31 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for BUD31 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for BUD31 gene:
Search GeneIP for patents involving BUD31
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for BUD31 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for BUD31 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BUD31 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BUD31 | | | OriGene Protein Over-expression Lysate for BUD31 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for BUD31 | | OriGene 3'-UTR Clone for BUD31 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BUD31 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BUD31 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat BUD31 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BUD31 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BUD31 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BUD31 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BUD31 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BUD31 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for BUD31 |
| |  |  |  |  | | | | |
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 | | | BUD31 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BUD31 |
|  |  |  | | | | ThermoFisher Antibodies for BUD31 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BUD31 |
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