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Aliases for BUD13 Gene

Aliases for BUD13 Gene

  • BUD13 Homolog 2 3 5
  • Functional Spliceosome-Associated Protein 71 2 3
  • BUD13 Homolog (S. Cerevisiae) 2
  • BUD13 Homolog (Yeast) 2
  • FSAP71 3
  • Cwc26 3

External Ids for BUD13 Gene

Previous GeneCards Identifiers for BUD13 Gene

  • GC11M116125
  • GC11M116618
  • GC11M112550

Summaries for BUD13 Gene

GeneCards Summary for BUD13 Gene

BUD13 (BUD13 Homolog) is a Protein Coding gene. GO annotations related to this gene include poly(A) RNA binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BUD13 Gene

Genomics for BUD13 Gene

Regulatory Elements for BUD13 Gene

Enhancers for BUD13 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11F117081 0.7 Ensembl 48.2 -308.3 -308303 0.2 ZNF202 ZNF680 ZNF654 ZFP64 ZBTB11 ZNF140 ZBTB8A REST ZNF623 ZNF518A BUD13 RNF214 ZPR1 APOA1 RPS27P19 LOC653303 GC11M117070 SIK3
GH11F117019 1.3 Ensembl ENCODE 22.4 -250.6 -250642 8.5 HDGF PKNOX1 MLX WRNIP1 ARID4B FEZF1 ZNF2 YY1 ZNF121 ZNF143 LOC653303 BUD13 RNF214 ZPR1 APOA1 RPS27P19 SIK3 ENSG00000224077 RNY4P6 GC11M117036
GH11F117009 1.1 Ensembl ENCODE 16.8 -238.2 -238239 2.5 INSM2 GTF3C2 ZNF121 ZNF366 FOS EGR2 ZNF280D ZEB2 TSHZ1 ZFP69B LOC653303 BUD13 RNF214 APOA1 RPS27P19 GC11P117017
GH11F117327 1.1 ENCODE 16.7 -555.2 -555220 2.2 HDGF PKNOX1 CREB3L1 ARID4B SIN3A ZNF207 ZNF143 FOS SP3 SP5 RNF214 BUD13 PCSK7 ENSG00000252992 RPS27P19 BACE1 ENSG00000250699 GC11M117336
GH11F116825 1.6 FANTOM5 Ensembl ENCODE 10.8 -60.4 -60408 16.6 HDGF PKNOX1 MLX ARID4B DMAP1 ZNF2 YY1 SLC30A9 ZNF143 FOS APOA5 APOA1 LOC653303 APOC3 TAGLN ZPR1 BUD13 LOC105369514 ENSG00000224077 SIK3
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around BUD13 on UCSC Golden Path with GeneCards custom track

Promoters for BUD13 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000321706 -2 2001 PKNOX1 CREB3L1 WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 ZNF143

Genomic Location for BUD13 Gene

Chromosome:
11
Start:
116,748,170 bp from pter
End:
116,772,998 bp from pter
Size:
24,829 bases
Orientation:
Minus strand

Genomic View for BUD13 Gene

Genes around BUD13 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BUD13 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BUD13 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BUD13 Gene

Proteins for BUD13 Gene

  • Protein details for BUD13 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BRD0-BUD13_HUMAN
    Recommended name:
    BUD13 homolog
    Protein Accession:
    Q9BRD0
    Secondary Accessions:
    • A8K0S0
    • Q96LS7

    Protein attributes for BUD13 Gene

    Size:
    619 amino acids
    Molecular mass:
    70521 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for BUD13 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for BUD13 Gene

Post-translational modifications for BUD13 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for BUD13 Gene

No data available for DME Specific Peptides for BUD13 Gene

Domains & Families for BUD13 Gene

Protein Domains for BUD13 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for BUD13 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9BRD0

UniProtKB/Swiss-Prot:

BUD13_HUMAN :
  • Belongs to the CWC26 family.
Family:
  • Belongs to the CWC26 family.
genes like me logo Genes that share domains with BUD13: view

No data available for Gene Families for BUD13 Gene

Function for BUD13 Gene

Gene Ontology (GO) - Molecular Function for BUD13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 22365833
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with BUD13: view
genes like me logo Genes that share phenotypes with BUD13: view

Animal Model Products

miRNA for BUD13 Gene

miRTarBase miRNAs that target BUD13

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for BUD13 Gene

Localization for BUD13 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for BUD13 gene
Compartment Confidence
nucleus 5
cytosol 2
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for BUD13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0070274 RES complex ISS 15565172
genes like me logo Genes that share ontologies with BUD13: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for BUD13 Gene

Pathways & Interactions for BUD13 Gene

SuperPathways for BUD13 Gene

No Data Available

Gene Ontology (GO) - Biological Process for BUD13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000398 mRNA splicing, via spliceosome ISS 15565172
GO:0006406 mRNA export from nucleus ISS 15565172
genes like me logo Genes that share ontologies with BUD13: view

No data available for Pathways by source and SIGNOR curated interactions for BUD13 Gene

Transcripts for BUD13 Gene

Unigene Clusters for BUD13 Gene

BUD13 homolog (S. cerevisiae):
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for BUD13 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b
SP1:
SP2: -
SP3: -

Relevant External Links for BUD13 Gene

GeneLoc Exon Structure for
BUD13
ECgene alternative splicing isoforms for
BUD13

Expression for BUD13 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for BUD13 Gene

Protein differential expression in normal tissues from HIPED for BUD13 Gene

This gene is overexpressed in Plasma (36.4) and Peripheral blood mononuclear cells (14.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for BUD13 Gene



Protein tissue co-expression partners for BUD13 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of BUD13 Gene:

BUD13

SOURCE GeneReport for Unigene cluster for BUD13 Gene:

Hs.437341
genes like me logo Genes that share expression patterns with BUD13: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for BUD13 Gene

Orthologs for BUD13 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for BUD13 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia BUD13 34 35
  • 99.57 (n)
cow
(Bos Taurus)
Mammalia BUD13 34 35
  • 86.03 (n)
dog
(Canis familiaris)
Mammalia BUD13 35
  • 84 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Bud13 34 16 35
  • 82.27 (n)
rat
(Rattus norvegicus)
Mammalia Bud13 34
  • 81.12 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia BUD13 35
  • 63 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia BUD13 35
  • 54 (a)
OneToOne
chicken
(Gallus gallus)
Aves -- 35
  • 69 (a)
OneToMany
BUD13 34 35
  • 64.36 (n)
lizard
(Anolis carolinensis)
Reptilia BUD13 35
  • 52 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia bud13 34
  • 56.43 (n)
Str.15096 34
African clawed frog
(Xenopus laevis)
Amphibia Xl.29018 34
zebrafish
(Danio rerio)
Actinopterygii BUD13 35
  • 53 (a)
OneToOne
wufi47e11 34
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.14099 34
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP011249 34
  • 46.68 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG13625 34 35
  • 45.99 (n)
worm
(Caenorhabditis elegans)
Secernentea R08D7.1 34 35
  • 46.06 (n)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes BUD13 37
sea squirt
(Ciona savignyi)
Ascidiacea CSA.9379 35
  • 40 (a)
OneToOne
Species where no ortholog for BUD13 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for BUD13 Gene

ENSEMBL:
Gene Tree for BUD13 (if available)
TreeFam:
Gene Tree for BUD13 (if available)

Paralogs for BUD13 Gene

Pseudogenes.org Pseudogenes for BUD13 Gene

genes like me logo Genes that share paralogs with BUD13: view

No data available for Paralogs for BUD13 Gene

Variants for BUD13 Gene

Sequence variations from dbSNP and Humsavar for BUD13 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs10488698 -- 116,763,231(-) ATTTT(C/T)GTCAC reference, missense
rs10488699 -- 116,761,784(-) CAGTC(A/G)CTAGA intron-variant
rs10790162 -- 116,768,388(+) GTACA(A/G)TATGA intron-variant
rs111284851 -- 116,751,460(+) CCTGT(C/T)TCTAC intron-variant
rs111344610 -- 116,755,800(+) GTTTA(-/T)TTTTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for BUD13 Gene

Variant ID Type Subtype PubMed ID
nsv1047727 CNV loss 25217958
nsv507 CNV deletion 18451855

Variation tolerance for BUD13 Gene

Residual Variation Intolerance Score: 59.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.21; 81.01% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for BUD13 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
BUD13

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BUD13 Gene

Disorders for BUD13 Gene

Relevant External Links for BUD13

Genetic Association Database (GAD)
BUD13
Human Genome Epidemiology (HuGE) Navigator
BUD13
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
BUD13

No disorders were found for BUD13 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BUD13 Gene

Publications for BUD13 Gene

  1. A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. (PMID: 21386085) Kraja A.T. … Borecki I.B. (Diabetes 2011) 3 46 64
  2. Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study. (PMID: 20442857) Suchindran S. … McCarthy J.J. (PLoS Genet. 2010) 3 46 64
  3. Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population. (PMID: 20571754) Fontaine-Bisson B. … Franks P.W. (Diabetologia 2010) 3 46 64
  4. A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia. (PMID: 19656773) Hegele R.A. … Wang J. (Hum. Mol. Genet. 2009) 3 46 64
  5. Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. (PMID: 18193044) Kathiresan S. … Orho-Melander M. (Nat. Genet. 2008) 3 46 64

Products for BUD13 Gene

Sources for BUD13 Gene

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