BTNL9 Gene
protein-coding GIFtS: 43
GCID: GC05P180467
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butyrophilin-like 9
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Aliases for BTNL9 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Butyrophilin-Like 91 2 | | FLJ325351 | | BTN32 | | VDLS19002 | | Butyrophilin 32 | | Butyrophilin-Like Protein 92 |
Export aliases for BTNL9 gene to outside databasesPrevious GC identifers: GC05P180577 GC05P180399 GC05P175192 |
Summaries for BTNL9 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| -- |
Genomic Views for BTNL9 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_023133.13
Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for BTNL9 Other transcription factors
Search SABiosciences Chromatin IP Primers for BTNL9
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BTNL9 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q35.3 Ensembl cytogenetic band: 5q35.3 HGNC cytogenetic band: 5q35.3BTNL9 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05P180467: view genomic region
(about GC identifiers)
Start:
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180,467,225 bp from pter |
End:
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180,488,523 bp from pter |
Size:
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21,299 bases |
Orientation:
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plus strand |
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Proteins for BTNL9 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: BTNL9_HUMAN, Q6UXG8 (See
protein sequence)Recommended Name: Butyrophilin-like protein 9 precursor Size: 535 amino acids; 59716 Da
Subcellular location: Membrane; Single-pass type I membrane protein (By similarity)
Secondary accessions: A6NL42 Q6P660 Q96DM5Alternative splicing: 3 isoforms: Q6UXG8-1 Q6UXG8-2 Q6UXG8-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for BTNL9: NX_Q6UXG8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6UXG8 BTNL9 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_689760.2 ENSEMBL proteins: ENSP00000366037 ENSP00000330200 ENSP00000425424 ENSP00000427345 ENSP00000366038 Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
BTNL9 for ontologies About GeneDecksing
BTNL9 Antibody Products: Assay Products for BTNL9: |
Protein
Domains / Families for BTNL9 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
BTNL9 for domains About GeneDecksing
5/10 InterPro domains/families (see all 10):Graphical View of Domain Structure for InterPro Entry Q6UXG8ProtoNet protein and cluster: Q6UXG8 2 Blocks protein families: IPB003879 Butyrophylin C-terminal DUF signature IPB006574 SPRY-associated domain
UniProtKB/Swiss-Prot: BTNL9_HUMAN, Q6UXG8Similarity: Belongs to the immunoglobulin superfamily. BTN/MOG familySimilarity: Contains 1 B30.2/SPRY domainSimilarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain |
Function for BTNL9 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BTNL9 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BTNL9 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: BTNL9 (NM_152547) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BTNL9 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BTNL9  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BTNL9 |
Animal Models: Mouse knock-out Btnl9tm1Lex for BTNL9 1 MGI phenotypic allele for Btnl9 (no phenotypes)
BTNL9 for phenotypes About GeneDecksing
|
Pathways & Interactions for BTNL9 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BTNL9
|
Drugs & Compounds for BTNL9 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for BTNL9 Search CenterWatch for drugs/clinical trials and news about BTNL9 
|
Transcripts for BTNL9 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for BTNL9 gene: NM_152547.4 Unigene Cluster for BTNL9: Butyrophilin-like 9 Hs.546502 [show with all ESTs]Unigene Representative Sequence: NM_15254711 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000376841 ENST00000327705(uc003mmt.3) ENST00000491209(uc011dhi.1) ENST00000515271 ENST00000513424 ENST00000511589 ENST00000509395 ENST00000511056 ENST00000506782 ENST00000512570 ENST00000376842
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BTNL9 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BTNL9 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: BTNL9 (NM_152547) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BTNL9 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BTNL9  |
Additional cDNA sequence: AK057097.1 AK298113.1 AK309516.1 AL833663.1 AY358358.1 BC029040.1 BC042112.1 BC062459.1 9 DOTS entries: DT.100016962 DT.435872 DT.95351135 DT.310817 DT.97819020 DT.40121472 DT.120803332 DT.120803340 DT.91701176 24/52 AceView cDNA sequences (see all 52): BC062459 BU677910 AI340345 CB267814 AW779597 BU149912 BC042112 BC029040 AW207175 BQ267852 AW466974 AK057097 AA621029 NM_152547 BX095991 AI792955 AY358358 Z24982 AW173612 BI916367 AA434447 BU740561 BF062849 AI679794 GeneLoc Exon Structure
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Expression for BTNL9 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| BTNL9 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: AGCCGCTGTG
About this image See BTNL9 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for BTNL9
SOURCE GeneReport for Unigene cluster: Hs.546502 SABiosciences Custom PCR Arrays for BTNL9
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BTNL9 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat BTNL9 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BTNL9 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BTNL9 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BTNL9 |
Orthologs for BTNL9 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for BTNL9 gene from 2/7 species (see all 7) About this table
ENSEMBL Gene Tree for BTNL9 (if available) TreeFam Gene Tree for BTNL9 (if available)  |
Paralogs for BTNL9 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for BTNL9 gene
- BTN3A22 BTN2A12 BTNL82 ERMAP2 BTN3A32 BTN2A22 HHLA22 CD2762
- BTNL102 MOG2 BTNL22 BTN3A12 VTCN12 BTN1A12 BTNL32
18/30 SIMAP similar genes for BTNL9 using alignment to 4 protein entries: BTNL9_HUMAN (see all proteins)
(see all similar genes):BTN3A2 MOG BTN3A3 BTN3A1 MEFV TRIM58 BTNL2 BTNL3 TRIM21 TRIM62 TRIM27 BTN1A1 BTNL8 SKINT1 TRIM68 BTN2A2 BT3.3 BTNL10
BTNL9 for paralogs About GeneDecksing
|
Genomic Variants for BTNL9 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 5 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
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HapMap Linkage Disequilibrium report for BTNL9 (180467225 - 180488523 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 15 variations for BTNL9 14 CNVs: 29766 53320 2613 93412 93411 81167 36380 81166 93410 93406 81168 93409 81165 9527 1 Indel: 33416  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BTNL9 |
|
Disorders
/ Diseases for BTNL9 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
BTNL9 for disorders About MalaCards
BTNL9 for disorders About GeneDecksing
1 disease from the University of Copenhagen DISEASES database for BTNL9:Batten disease Export disorders for BTNL9 gene to outside databases
|
Publications for BTNL9 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for BTNL9 gene integrated from 9 sources: (articles sorted by number of sources associating them with BTNL9) | |  | Utopia: connect your pdf to the dynamic world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- The DNA sequence and comparative analysis of human chromosome 5. (PubMed id 15372022)2 Schmutz J.... Rubin E.M. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- The cluster of BTN genes in the extended major histocompatibility complex. (PubMed id 11170752)9 Rhodes D.A.... Trowsdale J. (2001)
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External Searches for BTNL9 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
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Genome Databases showing BTNL9 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing BTNL9 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing BTNL9 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for BTNL9 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for BTNL9 gene: Search GeneIP for patents involving BTNL9
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for BTNL9 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for BTNL9 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BTNL9 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BTNL9 | | OriGene Protein Over-expression Lysate for BTNL9 | | Browse OriGene Fluorogenic Cell Assay Kits | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for BTNL9 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BTNL9 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BTNL9 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for BTNL9 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for BTNL9 | | OriGene Custom Protein Services for BTNL9 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat BTNL9 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BTNL9 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BTNL9 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BTNL9 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BTNL9 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BTNL9 |
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| | | Search Tocris compounds for BTNL9 |
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 | | BTNL9 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BTNL9 |
|  |  |  | | | Search ThermoFisher Antibodies for BTNL9 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BTNL9 |
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