Aliases for BTN3A3 Gene
External Ids for BTN3A3 Gene
Previous GeneCards Identifiers for BTN3A3 Gene
The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A3) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010]
GeneCards Summary for BTN3A3 Gene
BTN3A3 (Butyrophilin Subfamily 3 Member A3) is a Protein Coding gene. An important paralog of this gene is BTN3A1.
UniProtKB/Swiss-Prot for BTN3A3 Gene
Plays a role in T-cell responses in the adaptive immune response.