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BTN3A1 Gene

protein-coding   GIFtS: 56
GCID: GC06P026402

Butyrophilin, Subfamily 3, Member A1

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Butyrophilin, Subfamily 3, Member A11 2     BTN3.12
BTF52 3 5     Butyrophilin Subfamily 3 Member A12
CD2772 5     DJ45P21.3 (Butyrophilin, Subfamily 3, Member A1)2
BT3.12     CD277 Antigen3

External Ids:    HGNC: 11381   Entrez Gene: 111192   Ensembl: ENSG000000269507   OMIM: 6135935   UniProtKB: O004813   

Export aliases for BTN3A1 gene to outside databases

Previous GC identifers: GC06P026460 GC06P026465 GC06P026510 GC06P026345


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for BTN3A1 Gene:
The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode
type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY)
domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene
(MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem
duplication, resulting in 3 copies of each (summary by Smith et al., 2010 (PubMed 20208008)).(supplied by OMIM,
Nov 2010)

GeneCards Summary for BTN3A1 Gene:
BTN3A1 (butyrophilin, subfamily 3, member A1) is a protein-coding gene. An important paralog of this gene is BTN3A2.

UniProtKB/Swiss-Prot: BT3A1_HUMAN, O00481
Function: Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of
activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of
T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated
metabolites, such as isopentenyl pyrophosphate

Gene Wiki entry for BTN3A1 (Butyrophilin, subfamily 3, member A1) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NT_007592.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the BTN3A1 gene promoter:
         Elk-1   p53   MyoD   NF-kappaB   POU2F1   NF-kappaB2   POU2F1a   STAT3   NF-kappaB1   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBTN3A1 promoter sequence
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Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BTN3A1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p22.1   Ensembl cytogenetic band:  6p22.2   HGNC cytogenetic band: 6p22.1

BTN3A1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BTN3A1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P026402:  view genomic region     (about GC identifiers)

Start:
26,402,465 bp from pter      End:
26,415,444 bp from pter
Size:
12,980 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: BT3A1_HUMAN, O00481 (See protein sequence)
Recommended Name: Butyrophilin subfamily 3 member A1 precursor  
Size: 513 amino acids; 57677 Da
Subunit: Homodimer
Sequence caution: Sequence=CAA69164.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
5 PDB 3D structures from and Proteopedia for BTN3A1:
4F80 (3D)        4F9L (3D)        4F9P (3D)        4JKW (3D)        4K55 (3D)    
Secondary accessions: A2A278 A8K2C8 B4DIQ1 B4DRM2 E9PGB4 E9PHG8 Q0P515 Q147X5 Q53F15 Q99420
Q9HCY1
Alternative splicing: 4 isoforms:  O00481-1   O00481-2   O00481-3   O00481-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for BTN3A1: NX_O00481

Explore proteomics data for BTN3A1 at MOPED

Post-translational modifications: 

  • N-glycosylated1
  • Ubiquitination2 at Lys83, Lys123
  • Glycosylation2 at Asn115
  • Modification sites at PhosphoSitePlus

  • See BTN3A1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001138480.1  NP_001138481.1  NP_008979.3  NP_919423.1  

    ENSEMBL proteins: 
     ENSP00000420010   ENSP00000289361   ENSP00000394937   ENSP00000396684   ENSP00000399393  
     ENSP00000427013   ENSP00000406667  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    C2SET: Immunoglobulin superfamily / C2-set domain containing
    CD: CD molecules
    BTN: Butyrophilins
    VSET: Immunoglobulin superfamily / V-set domain containing

    Selected InterPro protein domains (see all 11):
     IPR013162 CD80_C2-set
     IPR001870 B30.2/SPRY
     IPR013783 Ig-like_fold
     IPR013106 Ig_V-set
     IPR003879 Butyrophylin

    Graphical View of Domain Structure for InterPro Entry O00481

    ProtoNet protein and cluster: O00481

    4 Blocks protein domains:
    IPB003599 Immunoglobulin subtype
    IPB003879 Butyrophylin C-terminal DUF signature
    IPB006574 SPRY-associated domain
    IPB013106 Immunoglobulin V-set


    UniProtKB/Swiss-Prot: BT3A1_HUMAN, O00481
    Similarity: Belongs to the immunoglobulin superfamily. BTN/MOG family
    Similarity: Contains 1 B30.2/SPRY domain
    Similarity: Contains 2 Ig-like V-type (immunoglobulin-like) domains


    Find genes that share domains with BTN3A1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BT3A1_HUMAN, O00481
    Function: Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of
    activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of
    T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated
    metabolites, such as isopentenyl pyrophosphate

         Genatlas biochemistry entry for BTN3A1:
    butyrophilin subfamily 3,member A1,B box family of proteins,involved in cell proliferation and development

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    Find genes that share ontologies with BTN3A1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for BTN3A1:
     Low eccentricity cells 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for BTN3A1

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    hsa-mir-20a-5p (MIRT050606), hsa-mir-324-5p (MIRT043159), hsa-mir-17-5p (MIRT051029), hsa-mir-335-5p (MIRT019201)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    BT3A1_HUMAN, O00481: Cell membrane; Single-pass type I membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    cytoskeleton1
    extracellular1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IDA--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with BTN3A1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for BTN3A1
    Interactions:

        Search GeneGlobe Interaction Network for BTN3A1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 19)

    Selected Interacting proteins for BTN3A1 (O004811 ENSP000002893614) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TFF1P041551, ENSP000002915274EBI-2809309,EBI-743871 STRING: ENSP00000291527
    SIRPAENSP000003483074STRING: ENSP00000348307
    TAPBPLENSP000002665564STRING: ENSP00000266556
    CD33ENSP000002622624STRING: ENSP00000262262
    SIRPB1ENSP000002794774STRING: ENSP00000279477
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0050663cytokine secretion IDA--
    GO:0050798activated T cell proliferation IMP--
    GO:0050852T cell receptor signaling pathway IDA--
    GO:0072643interferon-gamma secretion IMP--

    Find genes that share ontologies with BTN3A1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for BTN3A1 (BT3A1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for BTN3A1 gene (4 alternative transcripts): 
    NM_001145008.1  NM_001145009.1  NM_007048.5  NM_194441.2  

    Unigene Cluster for BTN3A1:

    Butyrophilin, subfamily 3, member A1
    Hs.191510  [show with all ESTs]
    Unigene Representative Sequence: NM_001145009
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000476549 ENST00000289361(uc011dkj.2 uc010jqj.3 uc003nhv.3 uc011dkk.2)
    ENST00000465690 ENST00000450085 ENST00000425234 ENST00000427334 ENST00000506698
    ENST00000414912 ENST00000082468 ENST00000513047 ENST00000502361
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    Additional mRNA sequence: 

    AK223474.1 AK290193.1 AK291162.1 AK295720.1 AK298652.1 AK299327.1 BC118586.1 BC121800.1 
    U90552.2 Y07827.1 

    15 DOTS entries:

    DT.65285590  DT.92446082  DT.102836536  DT.87017065  DT.95160550  DT.121381040  DT.91918557  DT.121381126 
    DT.95242557  DT.100800856  DT.100815709  DT.121381038  DT.121381066  DT.87017067  DT.95160541 

    Selected AceView cDNA sequences (see all 66):

    CR595855 BU147474 BX459745 AW805800 BC065567 AI863274 AW574553 BF516542 
    AA593110 AI680403 BQ933401 AA977088 BU178206 AA666140 CA309315 NM_007048 
    BU150507 CB268433 CB148209 AI565435 NM_194441 BV206528 BM542639 BE243007 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for BTN3A1    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6
    SP1:              -                                 
    SP2:                                                
    SP3:                                                
    SP4:              -     -                           


    ECgene alternative splicing isoforms for BTN3A1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    BTN3A1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGCTTGTCAA
    BTN3A1 Expression
    About this image

    BTN3A1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    BTN3A1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.191510

    UniProtKB/Swiss-Prot: BT3A1_HUMAN, O00481
    Tissue specificity: Detected on T-cells, natural killer cells, dendritic cells and macrophages (at protein level).
    Ubiquitous. Highly expressed in heart, pancreas and lung, Moderately expressed in placenta, liver and muscle

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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      --

    ENSEMBL Gene Tree for BTN3A1 (if available)
    TreeFam Gene Tree for BTN3A1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for BTN3A1 gene
    BTN3A22  BTN2A12  BTNL82  ERMAP2  BTN2A22  BTN3A32  MOG2  BTNL22  
    BTN1A12  BTNL92  BTNL32  
    15 SIMAP similar genes for BTN3A1 using alignment to 4 protein entries:     BT3A1_HUMAN (see all proteins):
    BTN3A2    BTN3A3    BT3.3    MOG    BTNL10    BTN2A1
    BTNL9    BTN1A1    BTN2A2    BTNL2    CD276    ERMAP
    BTN2A3P    BTNL3    BTNL8

    Find genes that share paralogs with BTN3A1           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for BTN3A1
    PGOHUM00000247830


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for BTN3A1 (see all 371)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1831897801,2
    --26400545(+) ACAGCA/GTGCCA 4 -- us2k10--------
    rs94677551,2
    C,F,H--26400550(+) ATGCCA/GCTGCA 4 -- us2k17Minor allele frequency- G:0.16NS EA WA CSA 413
    rs2015241911,2
    C--26400590(+) ATCTC-/AAAAAAA 4 -- us2k10--------
    rs801533431,2
    --26400806(+) GCTGGA/GGAGGA 4 -- us2k10--------
    rs1998228861,2
    C--26400896(+) TCTTG-/TTTTTT 4 -- us2k10--------
    rs1870785221,2
    --26400918(+) TTGTTC/TTGTTT 4 -- us2k10--------
    rs1441282841,2
    C--26400945(+) CAGGTA/GGTTGC 4 -- us2k10--------
    rs1399347251,2
    --26401074(+) AGGGCC/TGCTGC 4 -- us2k10--------
    rs1918869461,2
    --26401180(+) GGATCC/TCTTGG 4 -- us2k10--------
    rs17417381,2
    C,F,H--26401252(+) CTGCTA/GTCTAC 4 -- us2k1 tfbs318Minor allele frequency- G:0.07MN NS EA NA 2582

    HapMap Linkage Disequilibrium report for BTN3A1 (26402465 - 26415444 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for BTN3A1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2731730CNV Deletion23290073
    esv2731728CNV Deletion23290073
    dgv6440n71CNV Loss21882294
    nsv883491CNV Loss21882294
    nsv883499CNV Gain21882294
    nsv883496CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613593    OMIM disorders: --


    Find genes that share disorders with BTN3A1           About GenesLikeMe

    Genetic Association Database (GAD): BTN3A1
    Human Genome Epidemiology (HuGE) Navigator: BTN3A1 (1 document)

    Export disorders for BTN3A1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for BTN3A1 gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with BTN3A1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A 1.1-Mb transcript map of the hereditary hemochromatosis locus. (PubMed id 9149941)1, 2, 3 Ruddy D.A.... Feder J.N. (Genome Res. 1997)
    2. Cloning, localization, and structure of new members of the butyrophilin gene family in the juxta-telomeric region of the major histocompatibility complex. (PubMed id 9382921)1, 2, 9 Tazi-Ahnini R.... Pontarotti P. (Immunogenetics 1997)
    3. The molecular basis for modulation of human Vgamma9Vdelta2 T cell responses by CD277/butyrophilin-3 (BTN3A)-specific antibodies. (PubMed id 22846996)1, 2 Palakodeti A.... Adams E.J. (J. Biol. Chem. 2012)
    4. Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human gammadelta T-cell subset. (PubMed id 22767497)1, 2 Harly C.... Scotet E. (Blood 2012)
    5. Differential role for CD277 as a co-regulator of the immune signal in T and NK cells. (PubMed id 21918970)1, 2 Messal N.... Olive D. (Eur. J. Immunol. 2011)
    6. CD277 is a negative co-stimulatory molecule universally expressed by ovarian cancer microenvironmental cells. (PubMed id 21113407)1, 2 Cubillos-Ruiz J.R.... Conejo-Garcia J.R. (Oncotarget 2010)
    7. Common variants on chromosome 6p22.1 are associated with schizophrenia. (PubMed id 19571809)1, 4 Shi J....Gejman P.V. (Nature 2009)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    9. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    10. Butyrophilin 3A1 binds phosphorylated antigens and stimulates human I^I' T cells. (PubMed id 23872678)1 Vavassori S....De Libero G. (Nat. Immunol. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 11119 HGNC: 1138 AceView: BTN3A1 Ensembl:ENSG00000026950 euGenes: HUgn11119
    ECgene: BTN3A1 H-InvDB: BTN3A1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for BTN3A1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for BTN3A1 gene:
    Search GeneIP for patents involving BTN3A1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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