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Aliases for BTN2A3P Gene

Aliases for BTN2A3P Gene

  • Butyrophilin, Subfamily 2, Member A3, Pseudogene 2 3
  • BTN2A3 3 4 6
  • Butyrophilin, Subfamily 2, Member A Pseudogene 3
  • Butyrophilin, Subfamily 2, Member A3 2
  • BTN2.3 3

External Ids for BTN2A3P Gene

Previous HGNC Symbols for BTN2A3P Gene

  • BTN2A3

Previous GeneCards Identifiers for BTN2A3P Gene

  • GC06P026425
  • GC06P026426
  • GC06P026428
  • GC06P026430
  • GC06P026431

Summaries for BTN2A3P Gene

Entrez Gene Summary for BTN2A3P Gene

  • The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A3) and BTN3 (e.g., BNT3A1; MIM 613593) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010]

GeneCards Summary for BTN2A3P Gene

BTN2A3P (Butyrophilin, Subfamily 2, Member A3, Pseudogene) is a Pseudogene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BTN2A3P Gene

Genomics for BTN2A3P Gene

Genomic Location for BTN2A3P Gene

Start:
26,421,391 bp from pter
End:
26,432,383 bp from pter
Size:
10,993 bases
Orientation:
Plus strand

Genomic View for BTN2A3P Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for BTN2A3P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BTN2A3P Gene

No data available for Regulatory Elements for BTN2A3P Gene

Proteins for BTN2A3P Gene

  • Protein details for BTN2A3P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96KV6-BT2A3_HUMAN
    Recommended name:
    Putative butyrophilin subfamily 2 member A3
    Protein Accession:
    Q96KV6
    Secondary Accessions:
    • A6NEF4

    Protein attributes for BTN2A3P Gene

    Size:
    586 amino acids
    Molecular mass:
    65713 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAC69644.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for BTN2A3P Gene

Proteomics data for BTN2A3P Gene at MOPED

Post-translational modifications for BTN2A3P Gene

  • Glycosylation at Asn45, Asn112, Asn214, and Asn220
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for BTN2A3P Gene

Domains for BTN2A3P Gene

Gene Families for BTN2A3P Gene

HGNC:
  • BTN :Butyrophilins

Graphical View of Domain Structure for InterPro Entry

Q96KV6

UniProtKB/Swiss-Prot:

BT2A3_HUMAN :
  • Q96KV6
Domain:
  • Contains 1 B30.2/SPRY domain.
  • Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Family:
  • Belongs to the immunoglobulin superfamily. BTN/MOG family.
genes like me logo Genes that share domains with BTN2A3P: view

No data available for Suggested Antigen Peptide Sequences for BTN2A3P Gene

Function for BTN2A3P Gene

Phenotypes for BTN2A3P Gene

GenomeRNAi human phenotypes for BTN2A3P:
genes like me logo Genes that share phenotypes with BTN2A3P: view

miRNA for BTN2A3P Gene

miRTarBase miRNAs that target BTN2A3P

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for BTN2A3P Gene

Localization for BTN2A3P Gene

Subcellular locations from UniProtKB/Swiss-Prot for BTN2A3P Gene

Membrane; Single-pass type I membrane protein.

Gene Ontology (GO) - Cellular Components for BTN2A3P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with BTN2A3P: view

No data available for Subcellular locations from COMPARTMENTS for BTN2A3P Gene

Pathways for BTN2A3P Gene

SuperPathways for BTN2A3P Gene

No Data Available

Interacting Proteins for BTN2A3P Gene

Selected Interacting proteins: Q96KV6-BT2A3_HUMAN for BTN2A3P Gene via MINT

Symbol External ID(s) Details
--

Gene Ontology (GO) - Biological Process for BTN2A3P Gene

None

No data available for Pathways by source for BTN2A3P Gene

Transcripts for BTN2A3P Gene

mRNA/cDNA for BTN2A3P Gene

(14) Selected AceView cDNA sequences:
(4) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for BTN2A3P Gene

Butyrophilin, subfamily 2, member A3, pseudogene:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for BTN2A3P Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c
SP1: -
SP2:

Relevant External Links for BTN2A3P Gene

GeneLoc Exon Structure for
BTN2A3P
ECgene alternative splicing isoforms for
BTN2A3P

Expression for BTN2A3P Gene

mRNA expression in normal human tissues for BTN2A3P Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for BTN2A3P Gene

SOURCE GeneReport for Unigene cluster for BTN2A3P Gene Hs.729655

genes like me logo Genes that share expressions with BTN2A3P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for BTN2A3P Gene

Orthologs for BTN2A3P Gene

Evolution for BTN2A3P Gene

ENSEMBL:
Gene Tree for BTN2A3P (if available)
TreeFam:
Gene Tree for BTN2A3P (if available)

No data available for Orthologs for BTN2A3P Gene

Paralogs for BTN2A3P Gene

Selected SIMAP similar genes for BTN2A3P Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with BTN2A3P: view

No data available for Paralogs for BTN2A3P Gene

Variants for BTN2A3P Gene

Sequence variations from dbSNP and Humsavar for BTN2A3P Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs1741740 -- 26,428,614(+) CTGTT(A/G)AAGAC intron-variant
rs1796521 -- 26,421,164(+) AACCT(C/T)GGGGA upstream-variant-2KB
rs1796522 -- 26,422,032(+) GTTGG(A/G)CCCGA intron-variant
rs2076030 -- 26,426,628(-) CAGAA(C/T)CATTC intron-variant
rs2393652 -- 26,423,628(+) CATCA(A/G)TAATT nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for BTN2A3P Gene

Variant ID Type Subtype PubMed ID
dgv6440n71 CNV Loss 21882294
nsv883499 CNV Gain 21882294
esv2731730 CNV Deletion 23290073

Relevant External Links for BTN2A3P Gene

HapMap Linkage Disequilibrium report
BTN2A3P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BTN2A3P Gene

Disorders for BTN2A3P Gene

No disorders were found for BTN2A3P Gene.

No data available for UniProtKB/Swiss-Prot for BTN2A3P Gene

Publications for BTN2A3P Gene

  1. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. BTN1A1, the mammary gland butyrophilin, and BTN2A2 are both inhibitors of T cell activation. (PMID: 20208008) Smith I.A. … Trowsdale J. (J. Immunol. 2010) 3
  5. The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment. (PMID: 20467438) Arbuckle M.I. … Grant S.G. (EMBO Rep. 2010) 3

Products for BTN2A3P Gene

Sources for BTN2A3P Gene

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