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Aliases for BTN2A3P Gene

Aliases for BTN2A3P Gene

  • Butyrophilin, Subfamily 2, Member A3, Pseudogene 2 3
  • BTN2A3 3 4
  • Butyrophilin, Subfamily 2, Member A Pseudogene 3
  • Butyrophilin, Subfamily 2, Member A3 2
  • BTN2.3 3

External Ids for BTN2A3P Gene

Previous HGNC Symbols for BTN2A3P Gene

  • BTN2A3

Previous GeneCards Identifiers for BTN2A3P Gene

  • GC06P026425
  • GC06P026426
  • GC06P026428
  • GC06P026430
  • GC06P026431

Summaries for BTN2A3P Gene

Entrez Gene Summary for BTN2A3P Gene

  • The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A3) and BTN3 (e.g., BNT3A1; MIM 613593) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010]

GeneCards Summary for BTN2A3P Gene

BTN2A3P (Butyrophilin, Subfamily 2, Member A3, Pseudogene) is a Pseudogene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BTN2A3P Gene

Genomics for BTN2A3P Gene

Genomic Location for BTN2A3P Gene

26,421,391 bp from pter
26,432,383 bp from pter
10,993 bases
Plus strand

Genomic View for BTN2A3P Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for BTN2A3P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BTN2A3P Gene

No data available for Regulatory Elements for BTN2A3P Gene

Proteins for BTN2A3P Gene

  • Protein details for BTN2A3P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative butyrophilin subfamily 2 member A3
    Protein Accession:
    Secondary Accessions:
    • A6NEF4

    Protein attributes for BTN2A3P Gene

    586 amino acids
    Molecular mass:
    65713 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAC69644.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for BTN2A3P Gene

Proteomics data for BTN2A3P Gene at MOPED

Post-translational modifications for BTN2A3P Gene

  • Glycosylation at Asn 45, Asn 112, Asn 214, and Asn 220
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for BTN2A3P Gene

Domains & Families for BTN2A3P Gene

Gene Families for BTN2A3P Gene

Suggested Antigen Peptide Sequences for BTN2A3P Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 B30.2/SPRY domain.
  • Belongs to the immunoglobulin superfamily. BTN/MOG family.
  • Contains 1 B30.2/SPRY domain.
  • Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Belongs to the immunoglobulin superfamily. BTN/MOG family.
genes like me logo Genes that share domains with BTN2A3P: view

Function for BTN2A3P Gene

genes like me logo Genes that share phenotypes with BTN2A3P: view

miRNA for BTN2A3P Gene

miRTarBase miRNAs that target BTN2A3P

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for BTN2A3P

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for BTN2A3P Gene

Localization for BTN2A3P Gene

Subcellular locations from UniProtKB/Swiss-Prot for BTN2A3P Gene

Membrane; Single-pass type I membrane protein.

Gene Ontology (GO) - Cellular Components for BTN2A3P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with BTN2A3P: view

No data available for Subcellular locations from COMPARTMENTS for BTN2A3P Gene

Pathways & Interactions for BTN2A3P Gene

SuperPathways for BTN2A3P Gene

No Data Available

Interacting Proteins for BTN2A3P Gene

Selected Interacting proteins: Q96KV6-BT2A3_HUMAN for BTN2A3P Gene via MINT

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for BTN2A3P Gene


No data available for Pathways by source and SIGNOR curated interactions for BTN2A3P Gene

Drugs & Compounds for BTN2A3P Gene

No Compound Related Data Available

Transcripts for BTN2A3P Gene

mRNA/cDNA for BTN2A3P Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(14) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for BTN2A3P Gene

Butyrophilin, subfamily 2, member A3, pseudogene:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for BTN2A3P

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for BTN2A3P Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c
SP1: -

Relevant External Links for BTN2A3P Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for BTN2A3P Gene

mRNA expression in normal human tissues for BTN2A3P Gene

Protein differential expression in normal tissues from HIPED for BTN2A3P Gene

This gene is overexpressed in Urine (47.5) and Adipocyte (21.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for BTN2A3P Gene

SOURCE GeneReport for Unigene cluster for BTN2A3P Gene Hs.729655

genes like me logo Genes that share expression patterns with BTN2A3P: view

Protein tissue co-expression partners for BTN2A3P Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for BTN2A3P Gene

Orthologs for BTN2A3P Gene

Evolution for BTN2A3P Gene

Gene Tree for BTN2A3P (if available)
Gene Tree for BTN2A3P (if available)

No data available for Orthologs for BTN2A3P Gene

Paralogs for BTN2A3P Gene

(8) SIMAP similar genes for BTN2A3P Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with BTN2A3P: view

No data available for Paralogs for BTN2A3P Gene

Variants for BTN2A3P Gene

Sequence variations from dbSNP and Humsavar for BTN2A3P Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
VAR_049830 -
VAR_049831 -
VAR_049832 -

Structural Variations from Database of Genomic Variants (DGV) for BTN2A3P Gene

Variant ID Type Subtype PubMed ID
dgv6440n71 CNV Loss 21882294
nsv883499 CNV Gain 21882294
esv2731730 CNV Deletion 23290073

Relevant External Links for BTN2A3P Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for BTN2A3P Gene

Disorders for BTN2A3P Gene

Relevant External Links for BTN2A3P

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with BTN2A3P: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BTN2A3P Gene

Publications for BTN2A3P Gene

  1. The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment. (PMID: 20467438) Arbuckle M.I. … Grant S.G. (EMBO Rep. 2010) 67
  2. BTN1A1, the mammary gland butyrophilin, and BTN2A2 are both inhibitors of T cell activation. (PMID: 20208008) Smith I.A. … Trowsdale J. (J. Immunol. 2010) 67
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 67
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  5. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 67

Products for BTN2A3P Gene

Sources for BTN2A3P Gene

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