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Aliases for BTN2A3P Gene

Aliases for BTN2A3P Gene

  • Butyrophilin Subfamily 2 Member A3, Pseudogene 2 3 5
  • BTN2A3 3 4
  • Butyrophilin, Subfamily 2, Member A3, Pseudogene 2
  • Butyrophilin, Subfamily 2, Member A Pseudogene 3
  • Butyrophilin, Subfamily 2, Member A3 2
  • BTN2.3 3

External Ids for BTN2A3P Gene

Previous HGNC Symbols for BTN2A3P Gene

  • BTN2A3

Previous GeneCards Identifiers for BTN2A3P Gene

  • GC06P026425
  • GC06P026426
  • GC06P026428
  • GC06P026430
  • GC06P026431
  • GC06P026432
  • GC06P026437
  • GC06P026509

Summaries for BTN2A3P Gene

Entrez Gene Summary for BTN2A3P Gene

  • The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A3) and BTN3 (e.g., BNT3A1; MIM 613593) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010]

GeneCards Summary for BTN2A3P Gene

BTN2A3P (Butyrophilin Subfamily 2 Member A3, Pseudogene) is a Pseudogene.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BTN2A3P Gene

Genomics for BTN2A3P Gene

Regulatory Elements for BTN2A3P Gene

Enhancers for BTN2A3P Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06G026471 1.6 Ensembl ENCODE dbSUPER 15.8 +54.4 54390 7.6 HDGF FOXA2 PKNOX1 MLX ARNT WRNIP1 SIN3A ARID4B DMAP1 FEZF1 BTN3A2 BTN2A2 HMGN4 HCG11 BTN2A3P BTN2A1 RNU6-502P BTN1A1 LOC102724851 HIST1H2AH
GH06G026420 1.1 ENCODE 19.2 -0.1 -58 2.1 HDGF FOXA2 PKNOX1 CREB3L1 MLX ARNT ARID4B SIN3A ZNF2 YY1 BTN3A2 BTN2A3P BTN2A1 BTN3A1 ZNF391 ZNF322 HCG11 ENSG00000261353 BTN3A3
GH06G026341 1.7 Ensembl ENCODE dbSUPER 10.9 -79.2 -79201 1.6 MLX YBX1 ZNF143 ZNF548 ZNF263 SP3 NFYC TBX21 MEF2D SSRP1 ZNF322 BTN3A2 HMGN4 ABT1 TRIM38 BTN2A3P BTN2A2 HCG11 BTN3A1 HIST1H2AH
GH06G026349 1.6 Ensembl ENCODE dbSUPER 11 -70.2 -70185 3.4 FOXA2 PKNOX1 ARNT SIN3A ARID4B SLC30A9 ZNF766 FOS SP5 JUNB BTN3A2 BTN2A1 BTN2A2 BTN2A3P BTN3A1 BTN3A3 ENSG00000272312 LOC101928743
GH06G026363 1.4 ENCODE dbSUPER 11.3 -55.7 -55719 3.9 FOXA2 PKNOX1 CREB3L1 ARNT ARID4B SIN3A DMAP1 FEZF1 ZNF2 YY1 BTN3A2 HMGN4 ABT1 ENSG00000261353 BTN2A3P BTN2A2 HIST1H1D BTN3A1 GUSBP2 ZNF322
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around BTN2A3P on UCSC Golden Path with GeneCards custom track

Promoters for BTN2A3P Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000195032 309 1001 HDGF FOXA2 PKNOX1 ATF1 CREB3L1 MLX ARNT ARID4B SIN3A BRCA1

Genomic Location for BTN2A3P Gene

Chromosome:
6
Start:
26,421,391 bp from pter
End:
26,432,383 bp from pter
Size:
10,993 bases
Orientation:
Plus strand

Genomic View for BTN2A3P Gene

Genes around BTN2A3P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BTN2A3P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BTN2A3P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BTN2A3P Gene

Proteins for BTN2A3P Gene

  • Protein details for BTN2A3P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96KV6-BT2A3_HUMAN
    Recommended name:
    Putative butyrophilin subfamily 2 member A3
    Protein Accession:
    Q96KV6
    Secondary Accessions:
    • A6NEF4

    Protein attributes for BTN2A3P Gene

    Size:
    586 amino acids
    Molecular mass:
    65713 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAC69644.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for BTN2A3P Gene

Post-translational modifications for BTN2A3P Gene

  • Glycosylation at posLast=4545, Asn112, Asn214, and Asn220
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for BTN2A3P Gene

Domains & Families for BTN2A3P Gene

Gene Families for BTN2A3P Gene

Suggested Antigen Peptide Sequences for BTN2A3P Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96KV6

UniProtKB/Swiss-Prot:

BT2A3_HUMAN :
  • Belongs to the immunoglobulin superfamily. BTN/MOG family.
Family:
  • Belongs to the immunoglobulin superfamily. BTN/MOG family.
genes like me logo Genes that share domains with BTN2A3P: view

Function for BTN2A3P Gene

genes like me logo Genes that share phenotypes with BTN2A3P: view

Animal Model Products

miRNA for BTN2A3P Gene

miRTarBase miRNAs that target BTN2A3P

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for BTN2A3P Gene

Localization for BTN2A3P Gene

Subcellular locations from UniProtKB/Swiss-Prot for BTN2A3P Gene

Membrane; Single-pass type I membrane protein.

Gene Ontology (GO) - Cellular Components for BTN2A3P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with BTN2A3P: view

No data available for Subcellular locations from COMPARTMENTS for BTN2A3P Gene

Pathways & Interactions for BTN2A3P Gene

SuperPathways for BTN2A3P Gene

No Data Available

Interacting Proteins for BTN2A3P Gene

Selected Interacting proteins: Q96KV6-BT2A3_HUMAN for BTN2A3P Gene via IID

Symbol External ID(s) Details
RFPL4A

Gene Ontology (GO) - Biological Process for BTN2A3P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for BTN2A3P Gene

Drugs & Compounds for BTN2A3P Gene

No Compound Related Data Available

Transcripts for BTN2A3P Gene

mRNA/cDNA for BTN2A3P Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(14) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for BTN2A3P Gene

Butyrophilin, subfamily 2, member A3, pseudogene:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for BTN2A3P Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c
SP1: -
SP2:

Relevant External Links for BTN2A3P Gene

GeneLoc Exon Structure for
BTN2A3P
ECgene alternative splicing isoforms for
BTN2A3P

Expression for BTN2A3P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for BTN2A3P Gene

Protein differential expression in normal tissues from HIPED for BTN2A3P Gene

This gene is overexpressed in Urine (47.5) and Adipocyte (21.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for BTN2A3P Gene



Protein tissue co-expression partners for BTN2A3P Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of BTN2A3P Gene:

BTN2A3P

SOURCE GeneReport for Unigene cluster for BTN2A3P Gene:

Hs.729655
genes like me logo Genes that share expression patterns with BTN2A3P: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for BTN2A3P Gene

Orthologs for BTN2A3P Gene

Evolution for BTN2A3P Gene

ENSEMBL:
Gene Tree for BTN2A3P (if available)
TreeFam:
Gene Tree for BTN2A3P (if available)

No data available for Orthologs for BTN2A3P Gene

Paralogs for BTN2A3P Gene

(8) SIMAP similar genes for BTN2A3P Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with BTN2A3P: view

No data available for Paralogs for BTN2A3P Gene

Variants for BTN2A3P Gene

Sequence variations from dbSNP and Humsavar for BTN2A3P Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1000520490 -- 26,422,407(+) AAAAA(A/T)TAAAT intron-variant
rs1000539073 -- 26,426,023(+) TGGAT(C/T)CTTTC intron-variant
rs1000590007 -- 26,425,595(+) AGACG(G/T)ATCCT intron-variant
rs1000744464 -- 26,429,077(+) TGCTT(C/T)AGTGG intron-variant
rs1000976106 -- 26,422,758(+) AGTTA(C/G)TGCTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for BTN2A3P Gene

Variant ID Type Subtype PubMed ID
dgv5927n100 CNV gain 25217958
dgv5928n100 CNV loss 25217958
esv2731730 CNV deletion 23290073
esv2763996 CNV gain 21179565
esv3576106 CNV gain 25503493
esv3608402 CNV loss 21293372
esv3890802 CNV loss 25118596
nsv1017824 CNV gain+loss 25217958
nsv1023453 CNV gain 25217958
nsv477034 CNV novel sequence insertion 20440878
nsv601184 CNV gain 21841781
nsv969358 CNV duplication 23825009

Relevant External Links for BTN2A3P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
BTN2A3P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for BTN2A3P Gene

Disorders for BTN2A3P Gene

Relevant External Links for BTN2A3P

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
BTN2A3P

No disorders were found for BTN2A3P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BTN2A3P Gene

Publications for BTN2A3P Gene

  1. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4 64
  2. BTN1A1, the mammary gland butyrophilin, and BTN2A2 are both inhibitors of T cell activation. (PMID: 20208008) Smith I.A. … Trowsdale J. (J. Immunol. 2010) 3 64
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for BTN2A3P Gene

Sources for BTN2A3P Gene

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