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Aliases for BTN2A3P Gene

Aliases for BTN2A3P Gene

  • Butyrophilin Subfamily 2 Member A3, Pseudogene 2 3 5
  • BTN2A3 3 4
  • Butyrophilin, Subfamily 2, Member A3, Pseudogene 2
  • Butyrophilin, Subfamily 2, Member A Pseudogene 3
  • Butyrophilin, Subfamily 2, Member A3 2
  • BTN2.3 3

External Ids for BTN2A3P Gene

Previous HGNC Symbols for BTN2A3P Gene

  • BTN2A3

Previous GeneCards Identifiers for BTN2A3P Gene

  • GC06P026425
  • GC06P026426
  • GC06P026428
  • GC06P026430
  • GC06P026431
  • GC06P026432
  • GC06P026437

Summaries for BTN2A3P Gene

Entrez Gene Summary for BTN2A3P Gene

  • The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A3) and BTN3 (e.g., BNT3A1; MIM 613593) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010]

GeneCards Summary for BTN2A3P Gene

BTN2A3P (Butyrophilin Subfamily 2 Member A3, Pseudogene) is a Pseudogene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BTN2A3P Gene

Genomics for BTN2A3P Gene

Regulatory Elements for BTN2A3P Gene

Enhancers for BTN2A3P Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06F026420 0.6 ENCODE 19.2 -0.1 -58 2.1 PKNOX1 ATF1 MLX ARNT CREB3L1 ARID4B SIN3A ZNF48 BRCA1 ZNF2 BTN3A2 BTN2A3P BTN2A1 BTN3A1 ZNF391 ZNF322 HCG11 ENSG00000261353 BTN3A3
GH06F026471 0.8 Ensembl ENCODE 15.8 +54.4 54390 7.6 HDGF PKNOX1 ARNT MLX WRNIP1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 BTN3A2 HMGN4 BTN2A2 HCG11 BTN2A3P BTN2A1 RNU6-502P BTN1A1 ABT1 LOC102724851
GH06F026439 0.8 ENCODE 11.7 +19.1 19072 2.5 HDGF ATF1 CREB3L1 DMAP1 ZNF2 YY1 ZNF766 ZNF143 ZNF207 NFYC BTN3A2 BTN2A1 BTN3A1 HMGN4 BTN2A2 ABT1 BTN1A1 BTN2A3P BTN3A3
GH06F026363 0.2 ENCODE 11.3 -55.7 -55719 3.9 PKNOX1 CREB3L1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 SLC30A9 ZNF766 BTN3A2 HMGN4 ABT1 HIST1H2APS4 ENSG00000271071 HIST1H2APS5 VN1R11P HIST1H2BPS1 HIST1H2BA LOC442172
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around BTN2A3P on UCSC Golden Path with GeneCards custom track

Promoters for BTN2A3P Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for BTN2A3P Gene

26,421,391 bp from pter
26,432,383 bp from pter
10,993 bases
Plus strand

Genomic View for BTN2A3P Gene

Genes around BTN2A3P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BTN2A3P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BTN2A3P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BTN2A3P Gene

Proteins for BTN2A3P Gene

  • Protein details for BTN2A3P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative butyrophilin subfamily 2 member A3
    Protein Accession:
    Secondary Accessions:
    • A6NEF4

    Protein attributes for BTN2A3P Gene

    586 amino acids
    Molecular mass:
    65713 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAC69644.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for BTN2A3P Gene

Post-translational modifications for BTN2A3P Gene

  • Glycosylation at Asn 45, Asn 112, Asn 214, and Asn 220
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for BTN2A3P Gene

Domains & Families for BTN2A3P Gene

Gene Families for BTN2A3P Gene

Suggested Antigen Peptide Sequences for BTN2A3P Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 B30.2/SPRY domain.
  • Belongs to the immunoglobulin superfamily. BTN/MOG family.
  • Contains 1 B30.2/SPRY domain.
  • Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Belongs to the immunoglobulin superfamily. BTN/MOG family.
genes like me logo Genes that share domains with BTN2A3P: view

Function for BTN2A3P Gene

genes like me logo Genes that share phenotypes with BTN2A3P: view

Animal Model Products

miRNA for BTN2A3P Gene

miRTarBase miRNAs that target BTN2A3P

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for BTN2A3P Gene

Localization for BTN2A3P Gene

Subcellular locations from UniProtKB/Swiss-Prot for BTN2A3P Gene

Membrane; Single-pass type I membrane protein.

Gene Ontology (GO) - Cellular Components for BTN2A3P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with BTN2A3P: view

No data available for Subcellular locations from COMPARTMENTS for BTN2A3P Gene

Pathways & Interactions for BTN2A3P Gene

SuperPathways for BTN2A3P Gene

No Data Available

Interacting Proteins for BTN2A3P Gene

Selected Interacting proteins: Q96KV6-BT2A3_HUMAN for BTN2A3P Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for BTN2A3P Gene


No data available for Pathways by source and SIGNOR curated interactions for BTN2A3P Gene

Transcripts for BTN2A3P Gene

mRNA/cDNA for BTN2A3P Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(14) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for BTN2A3P Gene

Butyrophilin, subfamily 2, member A3, pseudogene:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for BTN2A3P Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c
SP1: -

Relevant External Links for BTN2A3P Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for BTN2A3P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for BTN2A3P Gene

Protein differential expression in normal tissues from HIPED for BTN2A3P Gene

This gene is overexpressed in Urine (47.5) and Adipocyte (21.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for BTN2A3P Gene

Protein tissue co-expression partners for BTN2A3P Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of BTN2A3P Gene:


SOURCE GeneReport for Unigene cluster for BTN2A3P Gene:

genes like me logo Genes that share expression patterns with BTN2A3P: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for BTN2A3P Gene

Orthologs for BTN2A3P Gene

Evolution for BTN2A3P Gene

Gene Tree for BTN2A3P (if available)
Gene Tree for BTN2A3P (if available)

No data available for Orthologs for BTN2A3P Gene

Paralogs for BTN2A3P Gene

(8) SIMAP similar genes for BTN2A3P Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with BTN2A3P: view

No data available for Paralogs for BTN2A3P Gene

Variants for BTN2A3P Gene

Sequence variations from dbSNP and Humsavar for BTN2A3P Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs10447390 -- 26,419,824(+) TACTT(C/G)CTATG intron-variant, upstream-variant-2KB
rs10447391 -- 26,420,197(+) GCTGA(G/T)CCCTA intron-variant, upstream-variant-2KB
rs10946827 -- 26,426,073(+) CTGGT(A/G)TTCTC intron-variant
rs10946828 -- 26,426,088(+) ATCAA(A/T)GTTCT intron-variant
rs10946829 -- 26,426,259(+) AGCCC(A/G)TCATT intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for BTN2A3P Gene

Variant ID Type Subtype PubMed ID
dgv5927n100 CNV gain 25217958
dgv5928n100 CNV loss 25217958
esv2731730 CNV deletion 23290073
esv2763996 CNV gain 21179565
esv3576106 CNV gain 25503493
esv3608402 CNV loss 21293372
esv3890802 CNV loss 25118596
nsv1017824 CNV gain+loss 25217958
nsv1023453 CNV gain 25217958
nsv477034 CNV novel sequence insertion 20440878
nsv601184 CNV gain 21841781
nsv969358 CNV duplication 23825009

Relevant External Links for BTN2A3P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for BTN2A3P Gene

Disorders for BTN2A3P Gene

Relevant External Links for BTN2A3P

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for BTN2A3P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BTN2A3P Gene

Publications for BTN2A3P Gene

  1. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4 64
  2. BTN1A1, the mammary gland butyrophilin, and BTN2A2 are both inhibitors of T cell activation. (PMID: 20208008) Smith I.A. … Trowsdale J. (J. Immunol. 2010) 3 64
  3. The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment. (PMID: 20467438) Arbuckle M.I. … Grant S.G. (EMBO Rep. 2010) 3 64
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64

Products for BTN2A3P Gene

Sources for BTN2A3P Gene

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