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BTN2A2 Gene

protein-coding   GIFtS: 54
GCID: GC06P026383

Butyrophilin, Subfamily 2, Member A2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Butyrophilin, Subfamily 2, Member A21 2
BTF22 3 5
BT2.22 3
BTN2.22
Butyrophilin 22
Butyrophilin Subfamily 2 Member A22

External Ids:    HGNC: 11371   Entrez Gene: 103852   Ensembl: ENSG000001245087   OMIM: 6135915   UniProtKB: Q8WVV53   

Export aliases for BTN2A2 gene to outside databases

Previous GC identifers: GC06P026440 GC06P026445 GC06P026491 GC06P026332


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for BTN2A2 Gene:
Butyrophilin is the major protein associated with fat droplets in the milk. This gene is a member of the BTN2
subfamily of genes, which encode proteins belonging to the butyrophilin protein family. The gene is located in a
cluster on chromosome 6, consisting of seven genes belonging to the expanding B7/butyrophilin-like group, a
subset of the immunoglobulin gene superfamily. The encoded protein is a type I receptor glycoprotein involved in
lipid, fatty-acid and sterol metabolism. Several alternatively spliced transcript variants encoding different
isoforms have been found for this gene. (provided by RefSeq, Oct 2010)

GeneCards Summary for BTN2A2 Gene:
BTN2A2 (butyrophilin, subfamily 2, member A2) is a protein-coding gene. Diseases associated with BTN2A2 include hemochromatosis, and schizophrenia. An important paralog of this gene is BTN3A2.

UniProtKB/Swiss-Prot: BT2A2_HUMAN, Q8WVV5
Function: Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism
and IL2 and IFNG secretion (By similarity)

Gene Wiki entry for BTN2A2 (Butyrophilin, subfamily 2, member A2) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000006.12  NT_007592.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the BTN2A2 gene promoter:
         Elk-1   p53   MyoD   NF-kappaB   POU2F1   NF-kappaB2   POU2F1a   STAT3   NF-kappaB1   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBTN2A2 promoter sequence
   Search Chromatin IP Primers for BTN2A2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BTN2A2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p22.1   Ensembl cytogenetic band:  6p22.2   HGNC cytogenetic band: 6p22.1

BTN2A2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BTN2A2 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P026383:  view genomic region     (about GC identifiers)

Start:
26,383,324 bp from pter      End:
26,395,102 bp from pter
Size:
11,779 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: BT2A2_HUMAN, Q8WVV5 (See protein sequence)
Recommended Name: Butyrophilin subfamily 2 member A2 precursor  
Size: 523 amino acids; 59070 Da
Secondary accessions: A6NM84 B4DE97 B4DQ01 E9PH07 O00480
Alternative splicing: 5 isoforms:  Q8WVV5-1   Q8WVV5-2   Q8WVV5-3   Q8WVV5-4   Q8WVV5-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for BTN2A2: NX_Q8WVV5

Explore proteomics data for BTN2A2 at MOPED

Post-translational modifications: 

  • N-glycosylated (By similarity)1
  • Ubiquitination2 at Lys83, Lys105, Lys513
  • Glycosylation2 at Asn50, Asn118, Asn220, Asn226
  • Modification sites at PhosphoSitePlus

  • See BTN2A2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (6 alternative transcripts): 
    NP_001184166.1  NP_001184167.1  NP_001184168.1  NP_001184169.1  NP_008926.2  NP_853509.1  

    ENSEMBL proteins: 
     ENSP00000417472   ENSP00000418965   ENSP00000349143   ENSP00000337117   ENSP00000418857  
     ENSP00000419226   ENSP00000419451   ENSP00000394241   ENSP00000417676   ENSP00000418657  
     ENSP00000399308   ENSP00000417511   ENSP00000418176   ENSP00000417129  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    C2SET: Immunoglobulin superfamily / C2-set domain containing
    BTN: Butyrophilins
    VSET: Immunoglobulin superfamily / V-set domain containing

    Selected InterPro protein domains (see all 11):
     IPR013162 CD80_C2-set
     IPR001870 B30.2/SPRY
     IPR013783 Ig-like_fold
     IPR013106 Ig_V-set
     IPR003879 Butyrophylin

    Graphical View of Domain Structure for InterPro Entry Q8WVV5

    ProtoNet protein and cluster: Q8WVV5

    4 Blocks protein domains:
    IPB003599 Immunoglobulin subtype
    IPB003879 Butyrophylin C-terminal DUF signature
    IPB006574 SPRY-associated domain
    IPB013106 Immunoglobulin V-set


    UniProtKB/Swiss-Prot: BT2A2_HUMAN, Q8WVV5
    Similarity: Belongs to the immunoglobulin superfamily. BTN/MOG family
    Similarity: Contains 1 B30.2/SPRY domain
    Similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain
    Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain


    BTN2A2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BT2A2_HUMAN, Q8WVV5
    Function: Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism
    and IL2 and IFNG secretion (By similarity)

         Genatlas biochemistry entry for BTN2A2:
    butyrophilin subfamily 2,member A2,B box family of proteins,involved in cell proliferation and development

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    BTN2A2 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for BTN2A2:
     Increased cell number in G1, a  Increased circadian period len  Synthetic lethal with Ras 

    Animal Models:
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    hsa-miR-3678-3p
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    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    BT2A2_HUMAN, Q8WVV5: Membrane; Single-pass type I membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    extracellular2
    endoplasmic reticulum1
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    BTN2A2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for BTN2A2
    Interactions:

        Search GeneGlobe Interaction Network for BTN2A2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 20)

    Selected Interacting proteins for BTN2A2 (Q8WVV53 ENSP000003491434) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CREB3O438893I2D: score=1 
    SIRPAENSP000003483074STRING: ENSP00000348307
    TAPBPLENSP000002665564STRING: ENSP00000266556
    CD33ENSP000002622624STRING: ENSP00000262262
    NCR3LG1ENSP000003416374STRING: ENSP00000341637
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0031324negative regulation of cellular metabolic process ISS--
    GO:0046007negative regulation of activated T cell proliferation ISS--
    GO:0050710negative regulation of cytokine secretion ISS--

    BTN2A2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for BTN2A2 (BT2A2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for BTN2A2 gene (6 alternative transcripts): 
    NM_001197237.1  NM_001197238.1  NM_001197239.1  NM_001197240.1  NM_006995.4  NM_181531.2  

    Unigene Cluster for BTN2A2:

    Butyrophilin, subfamily 2, member A2
    Hs.373938  [show with all ESTs]
    Unigene Representative Sequence: NM_001197237
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000469230(uc003nhs.3) ENST00000490025 ENST00000356709(uc003nhq.3 uc003nhr.3 uc011dkh.2 uc011dkg.2 uc003nht.3)
    ENST00000467485(uc011dkf.2) ENST00000352867 ENST00000493275 ENST00000472507
    ENST00000482536 ENST00000432533 ENST00000482842 ENST00000482636 ENST00000471116
    ENST00000416795 ENST00000494184 ENST00000483410 ENST00000495632(uc011dki.1)

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    hsa-miR-3678-3p
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      QuantiTect SYBR Green Assays in human, mouse, rat BTN2A2
      QuantiFast Probe-based Assays in human, mouse, rat BTN2A2

    Additional mRNA sequence: 

    AK289883.1 AK293526.1 AK298570.1 BC013258.2 BC014021.2 BC017497.1 U90550.1 

    12 DOTS entries:

    DT.213193  DT.95375284  DT.40303942  DT.91765455  DT.100814077  DT.97845505  DT.121380997  DT.75101454 
    DT.91710456  DT.92009716  DT.101975063  DT.91765456 

    Selected AceView cDNA sequences (see all 60):

    BF870685 CB305707 BX106145 AL832800 R54384 BE328278 BE503839 BC013258 
    BP344944 AW772688 BU620822 BC017497 AI885174 BC014021 BE551924 NM_181531 
    CF125260 NM_006995 BX399136 CD655104 AA701423 AK123902 BG762043 BP345173 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for BTN2A2 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c
    SP1:                          -     -     -     -     -     -     -                           
    SP2:                                      -     -     -     -     -                           
    SP3:                                                                                          
    SP4:                                                                                          
    SP5:                                      -                                                   


    ECgene alternative splicing isoforms for BTN2A2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    BTN2A2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGGATGTGGT
    BTN2A2 Expression
    About this image

    BTN2A2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    BTN2A2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.373938

    UniProtKB/Swiss-Prot: BT2A2_HUMAN, Q8WVV5
    Tissue specificity: Highly expressed in brain, bone marrow, small intestine, muscle, spleen and pancreas. Moderate
    expression was seen in lung, liver and kidney

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for BTN2A2 gene from Selected species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Btn2a21 , 5 butyrophilin, subfamily 2, member A21, 5 77.36(n)1
    72.75(a)1
      13 (9.74 cM)5
    2385551  NM_175938.31  NP_787952.21 
     234776765 


    ENSEMBL Gene Tree for BTN2A2 (if available)
    TreeFam Gene Tree for BTN2A2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for BTN2A2 gene
    BTN3A22  BTN2A12  BTNL82  ERMAP2  BTN3A32  MOG2  BTNL22  BTN3A12  
    BTN1A12  BTNL32  BTNL92  
    Selected SIMAP similar genes for BTN2A2 using alignment to 9 protein entries:     BT2A2_HUMAN (see all proteins) (see all similar genes):
    BTN2A1    BTN2A3P    TRIM69    TRIM11    TRIM27    MEFV
    BTN1A1    MOG    BTNL2    BTN3A3    BTNL10    BTN3A1
    SKINTL    BTN3A2    BTNL3    BTNL9    BTNL8    ERMAP

    BTN2A2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for BTN2A2 (see all 380)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs77757201,2
    C,F,A,H--26381357(+) TTAATA/CGTGCT 5 -- us2k120Minor allele frequency- C:0.34NS EA WA NA CSA 2344
    rs1894818141,2
    --26381597(+) AGAAGA/TCAGGA 6 -- us2k10--------
    rs94677371,2
    C,F,A,H--26381630(+) GGTGTC/TAGAAG 6 -- us2k111Minor allele frequency- T:0.50NA WA CSA EA 372
    rs121895571,2
    C,A,H--26381638(+) AAGAGG/ACCGAG 6 -- us2k15Minor allele frequency- A:0.01NS EA NA 516
    rs94612461,2
    C,F,A,H--26381660(+) CAGGAG/ACATTC 6 -- us2k118Minor allele frequency- A:0.28NS EA NA WA CSA 2218
    rs583080951,2
    C,F--26381661(+) AGGAGC/TATTCA 6 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1465895361,2
    --26381693(+) GGCACC/GAAGGC 6 -- us2k10--------
    rs1139179531,2
    C,F--26381769(+) GGAGCG/ACTGGC 6 -- us2k11Minor allele frequency- A:0.50NA 2
    rs1497731331,2
    C--26381789(+) TGCAAC/TGTTGT 6 -- us2k10--------
    rs1456953431,2
    C--26381865(+) GGAATC/TGGAGG 6 -- us2k10--------

    HapMap Linkage Disequilibrium report for BTN2A2 (26383324 - 26395102 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for BTN2A2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2731730CNV Deletion23290073
    esv2731728CNV Deletion23290073
    dgv6440n71CNV Loss21882294
    nsv883491CNV Loss21882294
    nsv883499CNV Gain21882294
    nsv883496CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613591    OMIM disorders: --

    2 diseases for BTN2A2:    
    About MalaCards
    hemochromatosis    schizophrenia


    BTN2A2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): BTN2A2

    Export disorders for BTN2A2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for BTN2A2 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with BTN2A2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A 1.1-Mb transcript map of the hereditary hemochromatosis locus. (PubMed id 9149941)1, 2, 3 Ruddy D.A.... Feder J.N. (Genome Res. 1997)
    2. Common variants on chromosome 6p22.1 are associated with schizophrenia. (PubMed id 19571809)1, 4 Shi J....Gejman P.V. (Nature 2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    6. Structure and evolution of the extended B7 family. (PubMed id 10354554)1, 3 Henry J....Pontarotti P. (Immunol. Today 1999)
    7. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    8. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (Genome Res. 2004)
    9. A proteomic approach to evaluate the butyrophilin gene family expression in human milk fat globule membrane. (PubMed id 12124930)1 Cavaletto M....Conti A. (Proteomics 2002)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10385 HGNC: 1137 AceView: BTN2A2 Ensembl:ENSG00000124508 euGenes: HUgn10385
    ECgene: BTN2A2 H-InvDB: BTN2A2

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for BTN2A2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for BTN2A2 gene:
    Search GeneIP for patents involving BTN2A2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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