Aliases for BTN1A1 Gene
External Ids for BTN1A1 Gene
Previous HGNC Symbols for BTN1A1 Gene
Previous GeneCards Identifiers for BTN1A1 Gene
Butyrophilin is the major protein associated with fat droplets in the milk. It is a member of the immunoglobulin superfamily. It may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families [provided by RefSeq, Jul 2008]
GeneCards Summary for BTN1A1 Gene
BTN1A1 (Butyrophilin Subfamily 1 Member A1) is a Protein Coding gene. Among its related pathways are T Cell Co-Signaling Pathway: Ligand-Receptor Interactions. GO annotations related to this gene include receptor activity. An important paralog of this gene is BTNL8.
UniProtKB/Swiss-Prot for BTN1A1 Gene
May function in the secretion of milk-fat droplets. May act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane (By similarity). Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion (By similarity).