Aliases for BTN1A1 Gene
External Ids for BTN1A1 Gene
Previous Symbols for BTN1A1 Gene
Butyrophilin is the major protein associated with fat droplets in the milk. It is a member of the immunoglobulin superfamily. It may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families [provided by RefSeq, Jul 2008]
GeneCards Summary for BTN1A1 Gene
BTN1A1 (Butyrophilin, Subfamily 1, Member A1) is a Protein Coding gene. GO annotations related to this gene include receptor activity. An important paralog of this gene is BTNL9.
UniProtKB/Swiss-Prot for BTN1A1 Gene
May function in the secretion of milk-fat droplets. May act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane (By similarity). Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion (By similarity).