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BTN1A1 Gene

protein-coding   GIFtS: 54
GCID: GC06P026501

Butyrophilin, Subfamily 1, Member A1


(Previous symbol: BTN)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Butyrophilin, Subfamily 1, Member A11 2
BTN1 2 3 5
BT2 3
BTN12
BK14H9.2 (Butyrophilin, Subfamily 1, Member A1)2
Butyrophilin Subfamily 1 Member A12

External Ids:    HGNC: 11351   Entrez Gene: 6962   Ensembl: ENSG000001245577   OMIM: 6016105   UniProtKB: Q134103   

Export aliases for BTN1A1 gene to outside databases

Previous GC identifers: GC06P026558 GC06P026608 GC06P026444


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for BTN1A1 Gene:
Butyrophilin is the major protein associated with fat droplets in the milk. It is a member of the immunoglobulin
superfamily. It may have a cell surface receptor function. The human butyrophilin gene is localized in the major
histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the
shuffling of exons between 2 ancestral gene families (provided by RefSeq, Jul 2008)

GeneCards Summary for BTN1A1 Gene:
BTN1A1 (butyrophilin, subfamily 1, member A1) is a protein-coding gene. Diseases associated with BTN1A1 include encephalomyelitis, and pneumonia. GO annotations related to this gene include receptor activity. An important paralog of this gene is BTN3A2.

UniProtKB/Swiss-Prot: BT1A1_HUMAN, Q13410
Function: May function in the secretion of milk-fat droplets. May act as a specific membrane-associated receptor
for the association of cytoplasmic droplets with the apical plasma membrane (By similarity). Inhibits the
proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG
secretion (By similarity)

Gene Wiki entry for BTN1A1 (Butyrophilin, subfamily 1, member A1) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000006.12  NT_007592.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the BTN1A1 gene promoter:
         LHX3b/Lhx3b   Pbx1a   Pax-5   p53   Brachyury   FOXD1   Nkx6-1   FOXO1a   LHX3a/Lhx3a   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBTN1A1 promoter sequence
   Search Chromatin IP Primers for BTN1A1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BTN1A1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p22.1   Ensembl cytogenetic band:  6p22.2   HGNC cytogenetic band: 6p22.1

BTN1A1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BTN1A1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P026501:  view genomic region     (about GC identifiers)

Start:
26,501,449 bp from pter      End:
26,510,653 bp from pter
Size:
9,205 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: BT1A1_HUMAN, Q13410 (See protein sequence)
Recommended Name: Butyrophilin subfamily 1 member A1 precursor  
Size: 526 amino acids; 58960 Da
Subunit: Seems to associate with xanthine dehydrogenase/oxidase (By similarity)
Secondary accessions: Q4VAN3 Q4VAN4 Q9H458

Explore the universe of human proteins at neXtProt for BTN1A1: NX_Q13410

Explore proteomics data for BTN1A1 at MOPED

Post-translational modifications: 

  • N-glycosylated (By similarity)1
  • Glycosylation2 at Asn55, Asn215
  • Modification sites at PhosphoSitePlus

  • See BTN1A1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001723.2  
    ENSEMBL proteins: 
     ENSP00000244513  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    C2SET: Immunoglobulin superfamily / C2-set domain containing
    BTN: Butyrophilins
    VSET: Immunoglobulin superfamily / V-set domain containing

    Selected InterPro protein domains (see all 11):
     IPR013162 CD80_C2-set
     IPR001870 B30.2/SPRY
     IPR003596 Ig_V-set_subgr
     IPR013783 Ig-like_fold
     IPR013106 Ig_V-set

    Graphical View of Domain Structure for InterPro Entry Q13410

    ProtoNet protein and cluster: Q13410

    3 Blocks protein domains:
    IPB003596 Immunoglobulin V-type
    IPB003879 Butyrophylin C-terminal DUF signature
    IPB006574 SPRY-associated domain


    UniProtKB/Swiss-Prot: BT1A1_HUMAN, Q13410
    Similarity: Belongs to the immunoglobulin superfamily. BTN/MOG family
    Similarity: Contains 1 B30.2/SPRY domain
    Similarity: Contains 2 Ig-like V-type (immunoglobulin-like) domains


    BTN1A1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BT1A1_HUMAN, Q13410
    Function: May function in the secretion of milk-fat droplets. May act as a specific membrane-associated receptor
    for the association of cytoplasmic droplets with the apical plasma membrane (By similarity). Inhibits the
    proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG
    secretion (By similarity)

         Genatlas biochemistry entry for BTN1A1:
    butyrophilin,subfamily 1,member A1,B box family of proteins,involved in cell proliferation and development

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004872receptor activity TAS8611614
    GO:0005515protein binding ----
         
    BTN1A1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for BTN1A1:
     Increased HPV18 LCR reporter a 

         2 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Btn1a1):
     endocrine/exocrine gland  integument 

    BTN1A1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for BTN1A1: Btn1a1tm1Ihm Btn1a1tm2Ihm

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for BTN1A1
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for BTN1A1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for BTN1A1

    miRNA
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    1 qRT-PCR Assays for microRNA that regulate BTN1A1:
    hsa-miR-4291
    SwitchGear 3'UTR luciferase reporter plasmidBTN1A1 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector: BTN1A1 (NM_001732)
    Browse Sino Biological Human cDNA Clones
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BTN1A1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    BT1A1_HUMAN, Q13410: Membrane; Single-pass type I membrane protein. Secreted
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    plasma membrane4
    lysosome1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0005887integral component of plasma membrane TAS8611614

    BTN1A1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for BTN1A1
    Interactions:

        GeneGlobe Interaction Network for BTN1A1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 20)

    Selected Interacting proteins for BTN1A1 (Q134103 ENSP000002445134) via UniProtKB, MINT, STRING, and/or I2D (see all 20)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    XDHP479893, ENSP000003687274I2D: score=1 STRING: ENSP00000368727
    PLK1P533503, ENSP000003000934I2D: score=2 STRING: ENSP00000300093
    SIRPAENSP000003483074STRING: ENSP00000348307
    NCR3LG1ENSP000003416374STRING: ENSP00000341637
    TAPBPLENSP000002665564STRING: ENSP00000266556
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for BTN1A1 (BT1A1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for BTN1A1 gene: 
    NM_001732.2  

    Unigene Cluster for BTN1A1:

    Butyrophilin, subfamily 1, member A1
    Hs.153058  [show with all ESTs]
    Unigene Representative Sequence: U39576
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000244513(uc003nif.4)
    miRNA
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    1 qRT-PCR Assays for microRNA that regulate BTN1A1:
    hsa-miR-4291
    SwitchGear 3'UTR luciferase reporter plasmidBTN1A1 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector: BTN1A1 (NM_001732)
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    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat BTN1A1
      QuantiTect SYBR Green Assays in human, mouse, rat BTN1A1
      QuantiFast Probe-based Assays in human, mouse, rat BTN1A1

    Additional mRNA sequence: 

    BC096312.3 BC096313.1 BC096314.1 BC096315.1 U39576.1 

    2 DOTS entries:

    DT.453220  DT.121407003 

    10 AceView cDNA sequences:

    AA805147 BX106561 AA279987 AA280049 U39576 NM_001732 AA768577 AA731332 
    BU430550 AW977526 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    BTN1A1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGGCTTGTCT
    BTN1A1 Expression
    About this image


    BTN1A1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Heart (Cardiovascular System)
             Atrioventricular Node Cells Atrioventricular Node
     
     Ovary (Reproductive System)
             Oviduct
     
     Blood (Hematopoietic System)
             Proerythroblasts Hematopoietic Bone Marrow
     
     Brain (Nervous System)
             Cerebral Cortex
    BTN1A1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    BTN1A1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.153058
        Custom PCR Arrays for BTN1A1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BTN1A1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for BTN1A1 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Btn1a11 , 5 butyrophilin, subfamily 1, member A11, 5 80.18(n)1
    74.38(a)1
      13 (9.72 cM)5
    122311  NM_013483.31  NP_038511.11 
     234569925 
    chicken
    (Gallus gallus)
    Aves BTN1A11 butyrophilin, subfamily 1, member A1 54.63(n)
    42.13(a)
      420061  NM_001034817.2  NP_001029989.1 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC1001449471 uncharacterized LOC100144947 46.81(n)
    35.51(a)
      100144947  NM_001126519.1  NP_001119991.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1018850771 butyrophilin subfamily 1 member A1-like 50.27(n)
    39.34(a)
      101885077  XM_005163732.1  XP_005163789.1 


    ENSEMBL Gene Tree for BTN1A1 (if available)
    TreeFam Gene Tree for BTN1A1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for BTN1A1 gene
    BTN3A22  BTN2A12  BTNL82  ERMAP2  BTN2A22  BTN3A32  MOG2  BTN3A12  
    BTNL22  BTNL32  BTNL92  
    14 SIMAP similar genes for BTN1A1 using alignment to 3 protein entries:     BT1A1_HUMAN (see all proteins):
    MOG    TRIM11    BTN2A2    BTN2A3P    BTNL2    BTN3A3
    BTN2A1    BTN3A2    BTN3A1    BTNL8    BTNL9    BTNL3
    RFPL3    RFPL1

    BTN1A1 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for BTN1A1
    PGOHUM00000244693 PGOHUM00000243523


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for BTN1A1 (see all 228)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1498867411,2
    C,Funtested126505268(+) TCCAAG/AGGAGA 2 /K syn11Minor allele frequency- A:0.00NA 4550
    rs1893642491,2
    --26499576(+) ATAAAA/GACTTA 1 -- us2k10--------
    rs1819400701,2
    --26499578(+) AAAGAC/TTTATA 1 -- us2k10--------
    rs1850233291,2
    --26499593(+) AAGTGC/TATTAT 1 -- us2k10--------
    rs1902040451,2
    --26499660(+) AACAAC/TATTTT 1 -- us2k10--------
    rs1819028181,2
    --26499753(+) GAATTA/GAGGCT 1 -- us2k10--------
    rs745038241,2
    C--26499882(+) ATGATA/GAGTTG 1 -- us2k10--------
    rs69266291,2
    C,F,A,H--26499903(+) AATAAC/TTGTCA 1 -- us2k124Minor allele frequency- T:0.46NS EA NA WA CSA 2486
    rs69039731,2
    C,F,A,H--26499942(+) GAATTA/CACAGC 1 -- us2k121Minor allele frequency- C:0.46NS EA NA WA CSA 2330
    rs93937271,2
    C,F,A--26500011(+) ACGGAC/GGCTCC 1 -- us2k110Minor allele frequency- G:0.18NA WA EA 508

    HapMap Linkage Disequilibrium report for BTN1A1 (26501449 - 26510653 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for BTN1A1: --
    Human Gene Mutation Database (HGMD): BTN1A1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing BTN1A1
    DNA2.0 Custom Variant and Variant Library Synthesis for BTN1A1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 601610    OMIM disorders: --

    7 diseases for BTN1A1:    
    About MalaCards
    encephalomyelitis    pneumonia    tonsillitis    multiple sclerosis
    cerebritis    neuronitis    prostatitis


    BTN1A1 for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for BTN1A1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    mimicry 53 2 14978022 (1), 14688379 (1)

    Genetic Association Database (GAD): BTN1A1

    Export disorders for BTN1A1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for BTN1A1 gene, integrated from 10 sources (see all 31):
    (articles sorted by number of sources associating them with BTN1A1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels. (PubMed id 19084217)1, 4 Benyamin B....Visscher P.M. (Am. J. Hum. Genet. 2009)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    4. Cloning, localization, and structure of new members of the butyrophilin gene family in the juxta-telomeric region of the major histocompatibility complex. (PubMed id 9382921)1, 3 Tazi-Ahnini R.... Pontarotti P. (Immunogenetics 1997)
    5. Cloning and sequence analysis of human butyrophilin reveals a potential receptor function. (PubMed id 8611614)1, 2 Taylor M.R.... Couto J.R. (Biochim. Biophys. Acta 1996)
    6. Evolutionary study of multigenic families mapping close to the human MHC class I region. (PubMed id 8114113)1, 3 Vernet C....Pontarotti P. (J. Mol. Evol. 1993)
    7. The PRY/SPRY/B30.2 domain of butyrophilin 1A1 (BTN1A1) binds to xanthine oxidoreductase: implications for the function of BTN1A1 in the mammary gland and other tissues. (PubMed id 19531472)1, 9 Jeong J....Mather I.H. (J. Biol. Chem. 2009)
    8. The cluster of BTN genes in the extended major histocompatibility complex. (PubMed id 11170752)1, 9 Rhodes D.A.... Trowsdale J. (Genomics 2001)
    9. GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. (PubMed id 23722424)1 Rietveld C.A....Koellinger P.D. (Science 2013)
    10. Akt1 is essential for postnatal mammary gland development, function, and the expression of Btn1a1. (PubMed id 21915327)1 LaRocca J....Hixon M. (PLoS ONE 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 696 HGNC: 1135 AceView: BTN1A1 Ensembl:ENSG00000124557 euGenes: HUgn696
    ECgene: BTN1A1 H-InvDB: BTN1A1

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for BTN1A1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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