Aliases for BTLA Gene
External Ids for BTLA Gene
This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011]
GeneCards Summary for BTLA Gene
BTLA (B And T Lymphocyte Associated) is a Protein Coding gene. Diseases associated with BTLA include rheumatoid arthritis and subacute sclerosing panencephalitis. Among its related pathways are Class I MHC mediated antigen processing and presentation and CD28 co-stimulation. GO annotations related to this gene include receptor activity.
UniProtKB/Swiss-Prot for BTLA Gene
Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response.