Free for academic non-profit institutions. Other users need a Commercial license

Aliases for BTF3L4 Gene

Aliases for BTF3L4 Gene

  • Basic Transcription Factor 3-Like 4 2 3 4

External Ids for BTF3L4 Gene

Previous GeneCards Identifiers for BTF3L4 Gene

  • GC01P052234
  • GC01P052294
  • GC01P052521
  • GC01P050639

Summaries for BTF3L4 Gene

GeneCards Summary for BTF3L4 Gene

BTF3L4 (Basic Transcription Factor 3-Like 4) is a Protein Coding gene. An important paralog of this gene is BTF3.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BTF3L4 Gene

Genomics for BTF3L4 Gene

Regulatory Elements for BTF3L4 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for BTF3L4 Gene

52,056,125 bp from pter
52,090,716 bp from pter
34,592 bases
Plus strand

Genomic View for BTF3L4 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for BTF3L4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BTF3L4 Gene

Proteins for BTF3L4 Gene

  • Protein details for BTF3L4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transcription factor BTF3 homolog 4
    Protein Accession:
    Secondary Accessions:
    • B3KNJ1
    • D3DQ32
    • G3V1C6

    Protein attributes for BTF3L4 Gene

    158 amino acids
    Molecular mass:
    17271 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for BTF3L4 Gene


neXtProt entry for BTF3L4 Gene

Proteomics data for BTF3L4 Gene at MOPED

Post-translational modifications for BTF3L4 Gene

  • Ubiquitination at Lys8 and Lys115
  • Modification sites at PhosphoSitePlus

Other Protein References for BTF3L4 Gene

No data available for DME Specific Peptides for BTF3L4 Gene

Domains for BTF3L4 Gene

Protein Domains for BTF3L4 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 NAC-A/B (NAC-alpha/beta) domain.
  • Belongs to the NAC-beta family.
  • Contains 1 NAC-A/B (NAC-alpha/beta) domain.
  • Belongs to the NAC-beta family.
genes like me logo Genes that share domains with BTF3L4: view

No data available for Gene Families for BTF3L4 Gene

Function for BTF3L4 Gene

Gene Ontology (GO) - Molecular Function for BTF3L4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with BTF3L4: view

Animal Model Products

miRNA for BTF3L4 Gene

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for BTF3L4

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for BTF3L4 Gene

Localization for BTF3L4 Gene

Subcellular locations from

Jensen Localization Image for BTF3L4 Gene COMPARTMENTS Subcellular localization image for BTF3L4 gene
Compartment Confidence
nucleus 3
mitochondrion 2
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for BTF3L4 Gene

Pathways for BTF3L4 Gene

SuperPathways for BTF3L4 Gene

No Data Available

Gene Ontology (GO) - Biological Process for BTF3L4 Gene


No data available for Pathways by source for BTF3L4 Gene

Transcripts for BTF3L4 Gene

Unigene Clusters for BTF3L4 Gene

Basic transcription factor 3-like 4:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for BTF3L4

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for BTF3L4 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b
SP1: - - -
SP2: -
SP4: -

Relevant External Links for BTF3L4 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for BTF3L4 Gene

mRNA expression in normal human tissues for BTF3L4 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for BTF3L4 Gene

This gene is overexpressed in Fetal ovary (6.5).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for BTF3L4 Gene

SOURCE GeneReport for Unigene cluster for BTF3L4 Gene Hs.429839

genes like me logo Genes that share expressions with BTF3L4: view

Expression partners for BTF3L4 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for BTF3L4 Gene

Orthologs for BTF3L4 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for BTF3L4 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia BTF3L4 35
  • 95.78 (n)
  • 98.73 (a)
BTF3L4 36
  • 84 (a)
(Canis familiaris)
Mammalia LOC100687058 35
  • 97.26 (n)
  • 100 (a)
BTF3L4 36
  • 100 (a)
(Mus musculus)
Mammalia Btf3l4 35
  • 93.88 (n)
  • 100 (a)
Btf3l4 16
Btf3l4 36
  • 100 (a)
(Pan troglodytes)
Mammalia BTF3L4 35
  • 99.79 (n)
  • 100 (a)
BTF3L4 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Btf3l4 35
  • 93.88 (n)
  • 100 (a)
(Monodelphis domestica)
Mammalia BTF3L4 36
  • 100 (a)
(Ornithorhynchus anatinus)
Mammalia BTF3L4 36
  • 100 (a)
(Gallus gallus)
Aves BTF3L4 35
  • 88.19 (n)
  • 98.73 (a)
BTF3L4 36
  • 84 (a)
(Anolis carolinensis)
Reptilia BTF3L4 36
  • 99 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia btf3l4 35
  • 82.49 (n)
  • 96.2 (a)
(Danio rerio)
Actinopterygii LOC100006097 35
  • 80.8 (n)
  • 96.2 (a)
btf3l4 36
  • 96 (a)
btf3l4 36
  • 96 (a)
fruit fly
(Drosophila melanogaster)
Insecta bic 36
  • 61 (a)
CG11835 36
  • 13 (a)
(Caenorhabditis elegans)
Secernentea icd-1 35
  • 65.29 (n)
  • 72.41 (a)
icd-1 36
  • 64 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes BTT1 36
  • 30 (a)
EGD1 36
  • 38 (a)
EGD1 38
sea squirt
(Ciona savignyi)
Ascidiacea CSA.1484 36
  • 72 (a)
Species with no ortholog for BTF3L4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for BTF3L4 Gene

Gene Tree for BTF3L4 (if available)
Gene Tree for BTF3L4 (if available)

Paralogs for BTF3L4 Gene

Paralogs for BTF3L4 Gene

(1) SIMAP similar genes for BTF3L4 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with BTF3L4: view

Variants for BTF3L4 Gene

Sequence variations from dbSNP and Humsavar for BTF3L4 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1051986 -- 52,087,804(+) ATAGA(A/C)TCATC utr-variant-3-prime
rs2039582 -- 52,064,628(-) CAGTT(C/T)CTTTT intron-variant
rs2039583 -- 52,062,970(-) ATCAG(C/T)GGCAG intron-variant
rs2244540 -- 52,069,425(+) GCTAT(C/T)GCATT intron-variant
rs2783193 -- 52,059,054(+) AGCTT(G/T)TTTTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for BTF3L4 Gene

Variant ID Type Subtype PubMed ID
nsv829848 CNV Loss 17160897

Relevant External Links for BTF3L4 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BTF3L4 Gene

Disorders for BTF3L4 Gene

No disorders were found for BTF3L4 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for BTF3L4 Gene

Publications for BTF3L4 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for BTF3L4 Gene

Sources for BTF3L4 Gene

Back to Top