BTF3L4 Gene
protein-coding GIFtS: 43
GCID: GC01P052521
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basic transcription factor 3-like 4
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Aliases
for BTF3L4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Basic Transcription Factor 3-Like 41 2 3 | | MGC239081 | | Transcription Factor BTF3 Homolog 42 |
Export aliases for BTF3L4 gene to outside databasesPrevious GC identifers: GC01P052234 GC01P052294 GC01P050639 |
Summaries
for BTF3L4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for BTF3L4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the BTF3L4 gene promoter:
Elk-1 Sox5 RFX1 HOXA3 AML1a IRF-1 IRF-2 c-Myb FOXJ2
Other transcription factors
Search SABiosciences Chromatin IP Primers for BTF3L4
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BTF3L4 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p32.3 Ensembl cytogenetic band: 1p32.3 HGNC cytogenetic band: 1p32.3BTF3L4 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P052521: view genomic region
(about GC identifiers)
Start:
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52,521,797 bp from pter |
End:
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52,556,388 bp from pter |
Size:
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34,592 bases |
Orientation:
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plus strand |
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Proteins
for BTF3L4 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: BT3L4_HUMAN, Q96K17 (See
protein sequence)Recommended Name: Transcription factor BTF3 homolog 4 Size: 158 amino acids; 17271 Da
Secondary accessions: B3KNJ1 D3DQ32 G3V1C6Alternative splicing: 3 isoforms: Q96K17-1 Q96K17-2 Q96K17-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for BTF3L4: NX_Q96K17
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96K17
BTF3L4 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001129969.1 NP_001230696.1 NP_689478.1
ENSEMBL proteins: ENSP00000360664 ENSP00000434611 ENSP00000434824 ENSP00000436712 ENSP00000433418
Human Recombinant Protein Products:
BTF3L4 Antibody Products:
Assay Products for BTF3L4: |
Protein
Domains /
Families
for BTF3L4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
BTF3L4 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96K17ProtoNet protein and cluster: Q96K17 1 Blocks protein family: IPB002715 Nascent polypeptide-associated complex NAC
UniProtKB/Swiss-Prot: BT3L4_HUMAN, Q96K17Similarity: Belongs to the NAC-beta familySimilarity: Contains 1 NAC-A/B (NAC-alpha/beta) domain |
Function
for BTF3L4 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BTF3L4 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BTF3L4 (see all 3)
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BTF3L4 |
|
Pathways & Interactions
for BTF3L4 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BTF3L4
|
Drugs & Compounds
for BTF3L4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for BTF3L4
Search CenterWatch for drugs/clinical trials and news about BTF3L4 / BT3L4
|
Transcripts
for BTF3L4 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for BTF3L4 gene (3 alternative transcripts): NM_001136497.2 NM_001243767.1 NM_152265.4 Unigene Cluster for BTF3L4: Basic transcription factor 3-like 4 Hs.429839 [show with all ESTs]Unigene Representative Sequence: NM_1522658 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000313334(uc001ctk.3 uc001ctl.3 uc010onh.2) ENST00000477828
ENST00000489308 ENST00000526132 ENST00000472944 ENST00000524414 ENST00000484036
ENST00000533836
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BTF3L4 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BTF3L4 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): BTF3L4 (NM_152265) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BTF3L4 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BTF3L4 |
Additional cDNA sequence: AK027582.1 AK027750.1 BC021004.1 BC022371.1 BC070378.1 23 DOTS entries: DT.92410131 DT.100820002 DT.86859299 DT.102831610 DT.99932247 DT.97844981 DT.99960939 DT.100819996 DT.121387183 DT.437623 DT.121387108 DT.121387171 DT.92440193 DT.100819998 DT.408195 DT.100830610 DT.121387114 DT.121387161 DT.95149933 DT.95358320 DT.100820000 DT.121139678 DT.121387170 24/245 AceView cDNA sequences (see all 245): BE765938 BX112001 AI242377 CA443104 BM550747 AW275044 AA258419 BX337762 F02776 AI653085 BX378030 BI091785 BX280667 CR611839 BM973000 BF968617 F07408 AI038587 CA311647 AA888059 BM693269 CA312115 AK027582 BM930801
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for BTF3L4 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b |
|---|
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| SP1: | | | | | | | - | | | | - | | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | - | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for BTF3L4
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Expression
for BTF3L4 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| BTF3L4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGAACATCA
About this image
See BTF3L4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for BTF3L4
SOURCE GeneReport for Unigene cluster: Hs.429839
SABiosciences Custom PCR Arrays for BTF3L4
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BTF3L4
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat BTF3L4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BTF3L4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BTF3L4 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BTF3L4 |
Orthologs
for BTF3L4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for BTF3L4 gene from 8/32 species (see all 32) About this table
ENSEMBL Gene Tree for BTF3L4 (if available)
TreeFam Gene Tree for BTF3L4 (if available) |
Paralogs
for BTF3L4 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for BTF3L4 gene
- BTF32
1 SIMAP similar gene for BTF3L4 using alignment to 4 protein entries: BT3L4_HUMAN (see all proteins):BTF3
BTF3L4 for paralogs About GeneDecksing
5 Pseudogenes.org Pseudogenes for BTF3L4
PGOHUM00000239398 PGOHUM00000239042 PGOHUM00000241001 PGOHUM00000250739 PGOHUM00000243392
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Genomic Variants
for BTF3L4 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for BTF3L4 (52521797 - 52556388 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for BTF3L4
1 CNV: 4224 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BTF3L4 |
|
Disorders
/ Diseases
for BTF3L4 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
BTF3L4 for disorders About GeneDecksing
1  disease for BTF3L4: About MalaCardsmalaria
Export disorders for BTF3L4 gene to outside databases
|
Publications
for BTF3L4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for BTF3L4 gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with BTF3L4) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
|
External Searches for BTF3L4 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing BTF3L4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing BTF3L4 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing BTF3L4 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for BTF3L4 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for BTF3L4 gene:
Search GeneIP for patents involving BTF3L4
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for BTF3L4 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
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| |
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| |  |  |  |  | | | | |
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 | | | BTF3L4 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BTF3L4 |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BTF3L4 |
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