External Ids for BTC Gene
The protein encoded by this gene is a member of the EGF family of growth factors. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor. [provided by RefSeq, Jul 2008]
GeneCards Summary for BTC Gene
BTC (Betacellulin) is a Protein Coding gene. Diseases associated with BTC include endometrial cancer and pancreatic cancer. Among its related pathways are PI-3K cascade and PI-3K cascade. GO annotations related to this gene include growth factor activity and epidermal growth factor receptor binding. An important paralog of this gene is TGFA.
UniProtKB/Swiss-Prot for BTC Gene
Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.