BTBD7 Gene
protein-coding GIFtS: 44
GCID: GC14M093703
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BTB (POZ) domain containing 7
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Aliases
for BTBD7 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| BTB (POZ) Domain Containing 71 2 | | FUP11 2 5 | | FLJ106481 | | BTB/POZ Domain-Containing Protein 72 | | KIAA15253 |
Export aliases for BTBD7 gene to outside databasesPrevious GC identifers: GC14M091697 GC14M092776 GC14U900579 GC14M073884 |
Summaries
for BTBD7 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for BTBD7 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000014.8 NC_018925.1 NT_026437.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the BTBD7 gene promoter:
TBP Spz1 Sp1 LUN-1 GATA-1 MEF-2A HSF2 aMEF-2 TGIF Hlf
Other transcription factors
Search SABiosciences Chromatin IP Primers for BTBD7
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BTBD7 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 14q32.12 Ensembl cytogenetic band: 14q32.12 HGNC cytogenetic band: 14q32.13BTBD7 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14M093703: view genomic region
(about GC identifiers)
Start:
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93,703,896 bp from pter |
End:
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93,799,438 bp from pter |
Size:
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95,543 bases |
Orientation:
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minus strand |
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Proteins
for BTBD7 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: BTBD7_HUMAN, Q9P203 (See
protein sequence)Recommended Name: BTB/POZ domain-containing protein 7 Size: 1132 amino acids; 126368 Da
Sequence caution: Sequence=BAA96049.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;Sequence=BAB13946.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAB13946.1;Type=Miscellaneous discrepancy; Note=Probable cloning artifact; Sequence=CAH10736.1; Type=Miscellaneous discrepancy;Note=Probable cloning artifact;
Secondary accessions: A8K5V7 Q69Z05 Q7Z308 Q86TS0 Q9HAA4 Q9NVM0Alternative splicing: 3 isoforms: Q9P203-1 Q9P203-3 Q9P203-5 Explore the universe of human proteins at neXtProt for BTBD7: NX_Q9P203
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9P203
BTBD7 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001002860.2 NP_060637.1
ENSEMBL proteins: ENSP00000347246 ENSP00000335615 ENSP00000451010 ENSP00000450778 ENSP00000298896 ENSP00000451408 ENSP00000450704 ENSP00000376874
Human Recombinant Protein Products:
BTBD7 Antibody Products:
Assay Products for BTBD7: |
Protein
Domains /
Families
for BTBD7 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
BTBD7 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9P203ProtoNet protein and cluster: Q9P203 1 Blocks protein family: IPB000210 BTB/POZ domain
UniProtKB/Swiss-Prot: BTBD7_HUMAN, Q9P203Similarity: Contains 2 BTB (POZ) domains |
Function
for BTBD7 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BTBD7 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BTBD7 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): BTBD7 (NM_018167) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BTBD7 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BTBD7 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BTBD7 |
2 GenomeRNAi human phenotypes for BTBD7:
|
Pathways & Interactions
for BTBD7 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BTBD7
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for BTBD7 (ENSP000003356154) via UniProtKB, MINT, STRING, and/or I2DAbout this table
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Drugs & Compounds
for BTBD7 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for BTBD7
Search CenterWatch for drugs/clinical trials and news about BTBD7
|
Transcripts
for BTBD7 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for BTBD7 gene (2 alternative transcripts): NM_001002860.2 NM_018167.3 Unigene Cluster for BTBD7: BTB (POZ) domain containing 7 Hs.525549 [show with all ESTs]Unigene Representative Sequence: NM_0010028609 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000355125 ENST00000334746(uc010aur.3 uc010two.2 uc001ybo.3 uc001ybp.3)
ENST00000554565 ENST00000553975 ENST00000554644(uc001ybq.4) ENST00000298896(uc001ybr.3)
ENST00000555525 ENST00000554968 ENST00000393170
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BTBD7 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BTBD7 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): BTBD7 (NM_018167) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BTBD7 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BTBD7 |
Additional cDNA sequence: AB040958.2 AK001510.1 AK021953.1 AK074354.1 AK091287.1 AK291422.1 AK303355.1 AL049394.1 BC047071.1 BC141850.1 BX248762.1 BX538231.1 8 DOTS entries: DT.87046440 DT.312854 DT.95132183 DT.100683906 DT.91925100 DT.95102325 DT.100647641 DT.75104034
GeneLoc Exon Structure
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Expression
for BTBD7 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| BTBD7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCGAAACTCC
About this image
See BTBD7 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for BTBD7
SOURCE GeneReport for Unigene cluster: Hs.525549
SABiosciences Custom PCR Arrays for BTBD7
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BTBD7
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat BTBD7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BTBD7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BTBD7 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BTBD7 |
Orthologs
for BTBD7 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for BTBD7 gene from 6/17 species (see all 17) About this table
ENSEMBL Gene Tree for BTBD7 (if available)
TreeFam Gene Tree for BTBD7 (if available) |
Paralogs
for BTBD7 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for BTBD7 gene
BTBD7 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for BTBD7
PGOHUM00000238354 PGOHUM00000238923
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Genomic Variants
for BTBD7 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 14 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for BTBD7 (93703896 - 93799438 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for BTBD7
2 Indels: 66696 58699 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BTBD7 |
|
Disorders
/ Diseases
for BTBD7 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
BTBD7 for disorders About GeneDecksing
OMIM gene information: 610386
OMIM disorders: --
3  diseases for BTBD7: About MalaCardshepatocellular carcinoma carcinoma malaria
Export disorders for BTBD7 gene to outside databases
|
Publications
for BTBD7 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for BTBD7 gene integrated from 9 sources:
(articles sorted by number of sources associating them with BTBD7) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)1, 2, 3 Nagase T.... Ohara O. (2000)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- FUP1, a gene associated with hepatocellular carcinoma , stimulates NIH3T3 cell proliferation and tumor formation in nude mice. (PubMed id 11527404)1, 3 Pan W....Li T.P. (2001)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Strategy for comprehensive identification of human N-myristoylated proteins using an insect cell-free protein synthesis system. (PubMed id 20213681)2 Suzuki T.... Utsumi T. (2010)
- Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- The DNA sequence and analysis of human chromosome 14. (PubMed id 12508121)2 Heilig R.... Weissenbach J. (2003)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for BTBD7 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing BTBD7 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing BTBD7 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing BTBD7 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for BTBD7 gene:
Search GeneIP for patents involving BTBD7
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for BTBD7 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for BTBD7 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BTBD7 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BTBD7 | | | OriGene Protein Over-expression Lysate for BTBD7 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for BTBD7 | | OriGene 3'-UTR Clone for BTBD7 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BTBD7 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BTBD7 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for BTBD7 | | OriGene Custom Protein Services for BTBD7 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat BTBD7 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BTBD7 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BTBD7 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BTBD7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BTBD7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BTBD7 |
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 |  |  |  | |
| | | | Search Tocris compounds for BTBD7 |
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 | | | BTBD7 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BTBD7 |
|  |  |  | | | | Search ThermoFisher Antibodies for BTBD7 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BTBD7 |
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