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BTBD7 Gene

protein-coding   GIFtS: 47
GCID: GC14M093703

BTB (POZ) Domain Containing 7

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
BTB (POZ) Domain Containing 71 2
FUP12 5
BTB/POZ Domain-Containing Protein 72
KIAA15253

External Ids:    HGNC: 182691   Entrez Gene: 557272   Ensembl: ENSG000000111147   OMIM: 6103865   UniProtKB: Q9P2033   

Export aliases for BTBD7 gene to outside databases

Previous GC identifers: GC14M091697 GC14M092776 GC14U900579 GC14M073884


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for BTBD7 Gene:
BTBD7 (BTB (POZ) domain containing 7) is a protein-coding gene.

UniProtKB/Swiss-Prot: BTBD7_HUMAN, Q9P203
Function: Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced
following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering
SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion.
This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and
promotes cleft progression (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000014.8  NT_026437.13  NT_187601.1  NC_018925.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the BTBD7 gene promoter:
         TBP   Spz1   Sp1   LUN-1   GATA-1   MEF-2A   HSF2   aMEF-2   TGIF   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBTBD7 promoter sequence
   Search Chromatin IP Primers for BTBD7

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BTBD7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q32.12   Ensembl cytogenetic band:  14q32.12   HGNC cytogenetic band: 14q32.13

BTBD7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BTBD7 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M093703:  view genomic region     (about GC identifiers)

Start:
93,703,896 bp from pter      End:
93,799,438 bp from pter
Size:
95,543 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: BTBD7_HUMAN, Q9P203 (See protein sequence)
Recommended Name: BTB/POZ domain-containing protein 7  
Size: 1132 amino acids; 126368 Da
Sequence caution: Sequence=BAA96049.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=BAB13946.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAB13946.1;
Type=Miscellaneous discrepancy; Note=Probable cloning artifact; Sequence=CAH10736.1; Type=Miscellaneous
discrepancy; Note=Probable cloning artifact;
Secondary accessions: A8K5V7 Q69Z05 Q7Z308 Q86TS0 Q9HAA4 Q9NVM0
Alternative splicing: 3 isoforms:  Q9P203-1   Q9P203-3   Q9P203-5   

Explore the universe of human proteins at neXtProt for BTBD7: NX_Q9P203

Explore proteomics data for BTBD7 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See BTBD7 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001002860.2  NP_001276062.1  NP_060637.1  

    ENSEMBL proteins: 
     ENSP00000347246   ENSP00000335615   ENSP00000451010   ENSP00000450778   ENSP00000298896  
     ENSP00000451408   ENSP00000450704   ENSP00000376874  

    BTBD7 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for BTBD7

     
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    Search eBioscience for ELISAs for BTBD7 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    BTBD: BTB/POZ domain containing

    4 InterPro protein domains:
     IPR000210 BTB/POZ-like
     IPR011333 BTB/POZ_fold
     IPR013069 BTB_POZ
     IPR011705 BACK

    Graphical View of Domain Structure for InterPro Entry Q9P203

    ProtoNet protein and cluster: Q9P203

    1 Blocks protein domain: IPB000210 BTB/POZ domain

    UniProtKB/Swiss-Prot: BTBD7_HUMAN, Q9P203
    Similarity: Contains 1 BACK (BTB/Kelch associated) domain
    Similarity: Contains 2 BTB (POZ) domains


    Find genes that share domains with BTBD7           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BTBD7_HUMAN, Q9P203
    Function: Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced
    following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering
    SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion.
    This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and
    promotes cleft progression (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with BTBD7           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for BTBD7:
     Increased cell death HMECs cel  Increased homologous recombina 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for BTBD7
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    miRNA
    Products:
        
    miRTarBase miRNAs that target BTBD7:
    hsa-mir-92a-3p (MIRT049646), hsa-mir-21-5p (MIRT030753), hsa-mir-25-3p (MIRT050228), hsa-mir-218-5p (MIRT024240), hsa-mir-148b-3p (MIRT019286)

    Block miRNA regulation of human, mouse, rat BTBD7 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate BTBD7 (see all 155):
    hsa-miR-194* hsa-miR-140-5p hsa-miR-106a hsa-miR-3653 hsa-miR-138-2* hsa-miR-342-3p hsa-miR-519a hsa-miR-130b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Gene Editing
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BTBD7

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BTBD7


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    BTBD7_HUMAN, Q9P203: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--

    Find genes that share ontologies with BTBD7           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for BTBD7
    Interactions:

        Search GeneGlobe Interaction Network for BTBD7

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for BTBD7 (ENSP000003356154) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007275multicellular organismal development IEA--
    GO:0060693regulation of branching involved in salivary gland morphogenesis IEA--

    Find genes that share ontologies with BTBD7           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for BTBD7



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for BTBD7 gene (3 alternative transcripts): 
    NM_001002860.3  NM_001289133.1  NM_018167.4  

    Unigene Cluster for BTBD7:

    BTB (POZ) domain containing 7
    Hs.525549  [show with all ESTs]
    Unigene Representative Sequence: NM_001002860
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000355125 ENST00000334746(uc010aur.3 uc010two.2 uc001ybo.3 uc001ybp.3)
    ENST00000554565 ENST00000553975 ENST00000554644(uc001ybq.4) ENST00000298896(uc001ybr.3)
    ENST00000555525 ENST00000554968 ENST00000393170
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate BTBD7 (see all 155):
    hsa-miR-194* hsa-miR-140-5p hsa-miR-106a hsa-miR-3653 hsa-miR-138-2* hsa-miR-342-3p hsa-miR-519a hsa-miR-130b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BTBD7
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat BTBD7
      QuantiTect SYBR Green Assays in human, mouse, rat BTBD7
      QuantiFast Probe-based Assays in human, mouse, rat BTBD7

    Additional mRNA sequence: 

    AB040958.2 AK001510.1 AK021953.1 AK074354.1 AK091287.1 AK291422.1 AK303355.1 AL049394.1 
    BC047071.1 BC141850.1 BX248762.1 BX538231.1 

    8 DOTS entries:

    DT.87046440  DT.312854  DT.95132183  DT.100683906  DT.91925100  DT.95102325  DT.100647641  DT.75104034 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    BTBD7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCGAAACTCC
    BTBD7 Expression
    About this image

    BTBD7 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    BTBD7 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.525549
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BTBD7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for BTBD7 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Btbd71 , 5 BTB (POZ) domain containing 71, 5 90.43(n)1
    93.62(a)1
      12 (52.25 cM)5
    2383861  NM_172806.21  NP_766394.21 
     1027846565 
    chicken
    (Gallus gallus)
    Aves BTBD71 BTB (POZ) domain containing 7 82.1(n)
    88.85(a)
      423424  XM_004941881.1  XP_004941938.1 
    lizard
    (Anolis carolinensis)
    Reptilia BTBD76
    BTB (POZ) domain containing 7
    87(a)
    1 ↔ 1
    1(10835153-10891364)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia btbd71 BTB (POZ) domain containing 7 77.25(n)
    84.66(a)
      100486833  XM_002933211.2  XP_002933257.2 
    zebrafish
    (Danio rerio)
    Actinopterygii btbd71 BTB (POZ) domain containing 7 67.62(n)
    74.38(a)
      568372  NM_001025551.1  NP_001020722.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG169526
    --
    36(a)
    1 ↔ 1
    X(15764209-15769563)
    worm
    (Caenorhabditis elegans)
    Secernentea C39F7.56
    Protein C39F7.5 (C39F7.5) mRNA, complete cds
    27(a)
    1 ↔ 1
    V(1264773-1270104) WBGene00016540


    ENSEMBL Gene Tree for BTBD7 (if available)
    TreeFam Gene Tree for BTBD7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for BTBD7 gene

    Find genes that share paralogs with BTBD7           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for BTBD7
    PGOHUM00000238354 PGOHUM00000238923


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for BTBD7 (see all 1974)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1395586031,2
    Cuntested193709120(+) GAAGGA/C/GGAAGG 2 S syn11NA 4552
    rs112907861,2
    C--93703398(+) TTGCGT/-TTTTT 1 -- ds50011Minor allele frequency- -:0.00NA 2
    rs619917361,2
    C,F--93703572(+) GTTCAA/C/TGTGGG 1 -- ds50011NA 2
    rs1831554531,2
    C--93703602(+) CAATCA/CTGAAG 1 -- ds50010--------
    rs1452095081,2
    C--93703629(+) CTTTCC/TGCTCA 1 -- ds50010--------
    rs1426222081,2
    --93703723(+) ATTTCC/TGAGAA 1 -- ds50010--------
    rs1881841051,2
    --93703811(+) TCCCAA/GTTCTA 1 -- ds50010--------
    rs764793251,2
    F--93703819(+) CTACCC/ATCCAG 1 -- ds50011Minor allele frequency- A:0.01NA 120
    rs101479901,2
    C,F,H--93703854(+) AGACTA/GTATGC 1 -- ds500125Minor allele frequency- G:0.36NA NS EA WA CSA 2484
    rs1469153191,2
    --93704034(+) TGTATC/TGTTTT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for BTBD7 (93703896 - 93799438 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for BTBD7:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv820783CNV Duplication20802225
    esv26222CNV Loss19812545
    nsv820297CNV Loss19587683
    nsv518613CNV Loss19592680
    dgv383n67CNV Gain20364138

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing BTBD7
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610386    OMIM disorders: --


    Find genes that share disorders with BTBD7           About GenesLikeMe


    Export disorders for BTBD7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for BTBD7 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with BTBD7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2000)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. FUP1, a gene associated with hepatocellular carcinoma, stimulates NIH3T3 cell proliferation and tumor formation in nude mice. (PubMed id 11527404)1, 3 Pan W....Li T.P. (Biochem. Biophys. Res. Commun. 2001)
    5. BTB/POZ domain-containing protein 7: epithelial-mesenchymal transition promoter and prognostic biomarker of hepatocellular carcinoma. (PubMed id 23325674)1 Tao Y.M....Shen H. (Hepatology 2013)
    6. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    7. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    8. Strategy for comprehensive identification of human N-myristoylated proteins using an insect cell-free protein synthesis system. (PubMed id 20213681)2 Suzuki T.... Utsumi T. (Proteomics 2010)
    9. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
    10. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55727 HGNC: 18269 Ensembl:ENSG00000011114 euGenes: HUgn55727 ECgene: BTBD7
    H-InvDB: BTBD7

    (According to HUGE)
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    HUGE: KIAA1525

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for BTBD7 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for BTBD7 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for BTBD7 gene:
    Search GeneIP for patents involving BTBD7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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