Aliases for BTBD3 Gene
Aliases for BTBD3 Gene
External Ids for BTBD3 Gene
- HGNC: 15854
- Entrez Gene: 22903
- Ensembl: ENSG00000132640
- OMIM: 615566
- UniProtKB: Q9Y2F9
Previous GeneCards Identifiers for BTBD3 Gene
- GC20P011886
- GC20P011819
Summaries for BTBD3 Gene
GeneCards Summary for BTBD3 Gene
BTBD3 (BTB Domain Containing 3) is a Protein Coding gene. An important paralog of this gene is BTBD6.
UniProtKB/Swiss-Prot for BTBD3 Gene
-
Acts as a key regulator of dendritic field orientation during development of sensory cortex. Also directs dendrites toward active axon terminals when ectopically expressed (By similarity).
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BTBD3 Gene
Genomics for BTBD3 Gene
GeneHancer (GH) Regulatory Elements for BTBD3 Gene
Promoters and enhancers for BTBD3 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH20I011890 | Promoter/Enhancer | 2.2 | EPDnew Ensembl ENCODE | 559.7 | +3.0 | 2981 | 7.1 | PKNOX1 ARID4B SIN3A FEZF1 DMAP1 BRCA1 ZNF48 YY1 ZNF766 GLIS2 | BTBD3 ENSG00000236526 | |
| GH20I011917 | Promoter/Enhancer | 1.5 | EPDnew Ensembl ENCODE | 562.3 | +28.0 | 28043 | 3.1 | CTCF RFX1 TAF1 POLR2A RAD21 RFX5 | BTBD3 ENSG00000236526 PIR62959 | |
| GH20I011849 | Enhancer | 1 | FANTOM5 ENCODE | 23.3 | -39.0 | -39035 | 3.6 | KLF1 JUN MAX KLF17 RAD21 ZNF335 POLR2A ZNF366 ZSCAN5C ZNF143 | BTBD3 ENSG00000236526 GC20P011838 LINC00687 | |
| GH20I011806 | Enhancer | 1 | Ensembl ENCODE dbSUPER | 14 | -83.0 | -82992 | 2.5 | JUN CEBPB EP300 RAD21 JUND STAT3 FOS FOSL2 TCF7L2 | BTBD3 ENSG00000236526 RN7SKP111 LINC00687 LOC105372530 | |
| GH20I011809 | Enhancer | 0.7 | Ensembl ENCODE | 16.5 | -80.1 | -80131 | 1.4 | JUN FOS ZIC2 EZH2 | BTBD3 RN7SKP111 LINC00687 LOC105372530 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around BTBD3 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for BTBD3 Gene
Genomic Locations for BTBD3 Gene
- chr20:11,890,723-11,926,609
- (GRCh38/hg38)
- Size:
- 35,887 bases
- Orientation:
- Plus strand
- chr20:11,871,371-11,907,257
- (GRCh37/hg19)
Genomic View for BTBD3 Gene
Genes around BTBD3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 20p12.2 by Ensembl
- 20p12.2 by Entrez Gene
- 20p12.2 by HGNC
BTBD3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for BTBD3 Gene
Proteins for BTBD3 Gene
-
Protein details for BTBD3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9Y2F9-BTBD3_HUMAN
- Recommended name:
- BTB/POZ domain-containing protein 3
- Protein Accession:
- Q9Y2F9
- D3DW19
- Q5JY73
Protein attributes for BTBD3 Gene
- Size:
- 522 amino acids
- Molecular mass:
- 58420 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAA76796.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
Protein Expression for BTBD3 Gene
Post-translational modifications for BTBD3 Gene
- Ubiquitination at Lys315
Other Protein References for BTBD3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for BTBD3
-
Abcam antibodies for BTBD3
- Invitrogen Antibodies for BTBD3
- Search GeneTex for Antibodies for BTBD3
Protein Products
-
OriGene Purified Proteins for BTBD3
- Search Origene for MassSpec and Protein Over-expression Lysates for BTBD3
- Origene Custom Protein Services for BTBD3
- Search GeneTex for Proteins for BTBD3
-
Abcam proteins for BTBD3
Assay Products
No data available for DME Specific Peptides for BTBD3 Gene
Domains & Families for BTBD3 Gene
Gene Families for BTBD3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for BTBD3 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for BTBD3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for BTBD3 Gene
Function for BTBD3 Gene
Molecular function for BTBD3 Gene
- UniProtKB/Swiss-Prot Function:
- Acts as a key regulator of dendritic field orientation during development of sensory cortex. Also directs dendrites toward active axon terminals when ectopically expressed (By similarity).
Phenotypes From GWAS Catalog for BTBD3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0031625 | ubiquitin protein ligase binding | IBA | -- |
Phenotypes for BTBD3 Gene
- GenomeRNAi human phenotypes for BTBD3:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for BTBD3
-
-
ViGene Biosciences lentiviral particle packaged cDNA for BTBD3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for BTBD3 gene
- Search ViGene Biosciences for BTBD3
CRISPR Products
-
OriGene CRISPR knockouts for BTBD3
- genomics-online: gRNA clones - Search results for available BTBD3 gene related products
- Applied Biological Materials CRISPR for BTBD3
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for BTBD3
- GenScript: Design CRISPR guide RNA sequences for BTBD3
miRNA for BTBD3 Gene
- miRTarBase miRNAs that target BTBD3
-
- hsa-mir-181c-5p (MIRT006896)
- hsa-mir-148b-3p (MIRT019498)
- hsa-mir-130b-3p (MIRT020331)
- hsa-mir-181a-5p (MIRT025154)
- hsa-mir-148a-3p (MIRT026014)
- hsa-mir-98-5p (MIRT027774)
- hsa-mir-24-3p (MIRT030584)
- hsa-mir-21-5p (MIRT030995)
- hsa-mir-19b-3p (MIRT031218)
- hsa-mir-1227-3p (MIRT036405)
- hsa-mir-125b-5p (MIRT046061)
- hsa-mir-26a-5p (MIRT050122)
- hsa-mir-130a-3p (MIRT083127)
- hsa-mir-152-3p (MIRT083128)
- hsa-mir-301a-3p (MIRT083129)
- hsa-mir-454-3p (MIRT083130)
- hsa-mir-301b-3p (MIRT083131)
- hsa-mir-4295 (MIRT083134)
- hsa-mir-3666 (MIRT083135)
- hsa-mir-3668 (MIRT083136)
- hsa-mir-5000-5p (MIRT083137)
- hsa-mir-5680 (MIRT083138)
- hsa-mir-6502-3p (MIRT083140)
- hsa-mir-3613-3p (MIRT118221)
- hsa-mir-374a-5p (MIRT201379)
- hsa-mir-331-5p (MIRT201380)
- hsa-mir-374b-5p (MIRT201381)
- hsa-mir-3163 (MIRT201382)
- hsa-mir-3662 (MIRT201383)
- hsa-mir-6509-5p (MIRT201385)
- hsa-mir-3924 (MIRT201417)
- hsa-mir-185-5p (MIRT295292)
- hsa-mir-1253 (MIRT295294)
- hsa-mir-4306 (MIRT295295)
- hsa-mir-4644 (MIRT295296)
- hsa-mir-5197-3p (MIRT295297)
- hsa-mir-944 (MIRT349342)
- hsa-mir-3674 (MIRT349343)
- hsa-mir-770-5p (MIRT441099)
- hsa-mir-663b (MIRT480615)
- hsa-mir-7155-3p (MIRT480616)
- hsa-mir-3136-3p (MIRT480617)
- hsa-mir-5582-5p (MIRT480618)
- hsa-mir-6082 (MIRT480619)
- hsa-mir-598-3p (MIRT480620)
- hsa-mir-592 (MIRT480621)
- hsa-mir-597-5p (MIRT480622)
- hsa-mir-6499-3p (MIRT480623)
- hsa-mir-668-3p (MIRT480624)
- hsa-mir-483-3p (MIRT480625)
- hsa-mir-5692c (MIRT480626)
- hsa-mir-5692b (MIRT480627)
- hsa-mir-369-3p (MIRT480628)
- hsa-mir-4678 (MIRT480629)
- hsa-mir-491-5p (MIRT480630)
- hsa-mir-4450 (MIRT480631)
- hsa-mir-3119 (MIRT480632)
- hsa-mir-5192 (MIRT480633)
- hsa-mir-194-3p (MIRT480634)
- hsa-mir-1296-3p (MIRT480635)
- hsa-mir-4276 (MIRT485748)
- hsa-mir-3684 (MIRT485749)
- hsa-mir-7852-3p (MIRT485750)
- hsa-mir-4699-3p (MIRT524709)
- hsa-mir-4762-5p (MIRT624535)
- hsa-mir-32-3p (MIRT624536)
- hsa-mir-548t-3p (MIRT660093)
- hsa-mir-548ap-3p (MIRT660094)
- hsa-mir-548aa (MIRT660095)
- hsa-mir-548x-3p (MIRT660096)
- hsa-mir-548j-3p (MIRT660097)
- hsa-mir-548aq-3p (MIRT660098)
- hsa-mir-548am-3p (MIRT660099)
- hsa-mir-548aj-3p (MIRT660100)
- hsa-mir-548ah-3p (MIRT660101)
- hsa-mir-548ae-3p (MIRT660102)
- hsa-mir-548z (MIRT660103)
- hsa-mir-548h-3p (MIRT660104)
- hsa-mir-548d-3p (MIRT660105)
- hsa-mir-548bb-3p (MIRT660106)
- hsa-mir-548ac (MIRT660107)
- hsa-mir-4446-5p (MIRT660108)
- hsa-mir-5006-3p (MIRT660109)
- hsa-mir-4755-5p (MIRT660110)
- hsa-mir-3121-5p (MIRT660111)
- hsa-mir-4667-3p (MIRT660112)
- hsa-mir-1470 (MIRT660113)
miRNA Products
- Search ViGene Biosciences for BTBD3
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for BTBD3
- Browse OriGene Inhibitory RNA Products For BTBD3
- genomics-online: shRNA clones - Search results for available BTBD3 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for BTBD3 gene
Clone Products
-
OriGene ORF clones in human for BTBD3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for BTBD3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for BTBD3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available BTBD3 gene related products
- orf clones - Search results for available BTBD3 gene related products
- Applied Biological Materials Clones for BTBD3
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for BTBD3
-
ViGene Biosciences adenoviral particle packaged cDNA for BTBD3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for BTBD3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for BTBD3 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for BTBD3 Gene
Localization for BTBD3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for BTBD3 Gene
- Cytoplasm, cytosol. Nucleus. Note=Translocates from the cytosol to the nucleus in response to neuronal activity. {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| extracellular | 1 |
| peroxisome | 1 |
- Vesicles (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | ISS | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | ISS,IBA | -- |
| GO:0019005 | SCF ubiquitin ligase complex | IBA | -- |
Pathways & Interactions for BTBD3 Gene
No Data Available
Interacting Proteins for BTBD3 Gene
Selected Interacting proteins:
ENSP00000367471
Q9Y2F9-BTBD3_HUMAN
for BTBD3 Gene via
STRING
UniProtKB
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007399 | nervous system development | IEA | -- |
| GO:0021987 | cerebral cortex development | IBA,ISS | -- |
| GO:0030162 | regulation of proteolysis | IBA | -- |
| GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process | IBA | -- |
| GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | IBA | -- |
No data available for Pathways by source and SIGNOR curated interactions for BTBD3 Gene
Transcripts for BTBD3 Gene
mRNA/cDNA for BTBD3 Gene
- (9) REFSEQ mRNAs :
- (12) Additional mRNA sequences :
- (226) Selected AceView cDNA sequences:
- (15) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for BTBD3 Gene
CRISPR Products
-
OriGene CRISPR knockouts for BTBD3
- genomics-online: gRNA clones - Search results for available BTBD3 gene related products
- Applied Biological Materials CRISPR for BTBD3
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for BTBD3
- GenScript: Design CRISPR guide RNA sequences for BTBD3
miRNA Products
- Search ViGene Biosciences for BTBD3
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for BTBD3
- Browse OriGene Inhibitory RNA Products For BTBD3
- genomics-online: shRNA clones - Search results for available BTBD3 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for BTBD3 gene
Clone Products
-
OriGene ORF clones in human for BTBD3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for BTBD3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for BTBD3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available BTBD3 gene related products
- orf clones - Search results for available BTBD3 gene related products
- Applied Biological Materials Clones for BTBD3
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | · | 9c | · | 9d | · | 9e |
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| SP1: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||
| SP5: | - | - | |||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | |||||||||||||||||||||||||||||||||
| SP7: | - | ||||||||||||||||||||||||||||||||||||
| SP8: | - | - | |||||||||||||||||||||||||||||||||||
| SP9: |
Expression for BTBD3 Gene
mRNA differential expression in normal tissues according to GTEx for BTBD3 Gene
This gene is overexpressed in Brain - Cerebellar Hemisphere (x4.1).
This gene is overexpressed in Heart (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for BTBD3 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of BTBD3 Gene:
BTBD3SOURCE GeneReport for Unigene cluster for BTBD3 Gene:
Hs.709366Evidence on tissue expression from TISSUES for BTBD3 Gene
- Nervous system(5)
Primer Products
-
OriGene qPCR primer pairs for BTBD3
- genomics-online: primer clones - Search results for available BTBD3 gene related products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for BTBD3 Gene
Orthologs for BTBD3 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | BTBD3 33 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| oppossum (Monodelphis domestica) |
Mammalia | BTBD3 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | BTBD3 33 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Btbd3 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Btbd3 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | BTBD3 33 34 |
|
||
| chicken (Gallus gallus) |
Aves | BTBD3 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | BTBD3 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | btbd3 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | btbd3b 33 34 |
|
||
| sbcb776 33 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.7701 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG5319 35 |
|
|
|
| lute 34 33 |
|
OneToMany | |||
| CG17068 35 |
|
|
|||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP004234 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany | |
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.9981 33 |
|
- Species where no ortholog for BTBD3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for BTBD3 Gene
(19) SIMAP similar genes for BTBD3 Gene using alignment to 6 proteins:
Variants for BTBD3 Gene
| SNP ID | Clin | Chr 20 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000034732 | -- | 11,894,546(+) | C/T | genic_upstream_transcript_variant, intron_variant | |
| rs1000040497 | -- | 11,891,420(+) | G/A | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000092227 | -- | 11,897,974(+) | A/G | genic_upstream_transcript_variant, intron_variant | |
| rs1000116236 | -- | 11,916,141(+) | AGA/A | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000273896 | -- | 11,916,428(+) | C/T | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv168e55 | CNV | gain | 17911159 |
| esv2758782 | CNV | gain | 17122850 |
| esv3410659 | CNV | insertion | 20981092 |
| esv3645231 | CNV | gain | 21293372 |
| esv3645232 | CNV | gain | 21293372 |
| nsv7339 | OTHER | inversion | 18451855 |
| nsv833921 | CNV | gain | 17160897 |
Residual Variation Intolerance Score:
49.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.84;
34.59% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for BTBD3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- BTBD3
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BTBD3 Gene
Disorders for BTBD3 Gene
Additional Disease Information for BTBD3
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for BTBD3 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BTBD3 Gene
Publications for BTBD3 Gene
- Genome-wide examination of genetic variants associated with response to platinum-based chemotherapy in patients with small-cell lung cancer. (PMID: 20463552) Wu C … Lin D (Pharmacogenetics and genomics 2010) 3 44 58
- The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P … Rogers J (Nature 2001) 3 4 58
- Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10231032) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 1999) 3 4 58
- A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein MY … Mann M (Cell 2015) 3 58
- Salt-inducible kinase 3, SIK3, is a new gene associated with hearing. (PMID: 25060954) Wolber LE … Williams FM (Human molecular genetics 2014) 3 58
Products for BTBD3 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for BTBD3
- Search Origene for MassSpec and Protein Over-expression Lysates for BTBD3
- Origene Custom Protein Services for BTBD3
- Origene shrna, sirna, and RNAi products in human, mouse, rat for BTBD3
- Browse OriGene Inhibitory RNA Products For BTBD3
- OriGene qPCR primer pairs for BTBD3
- OriGene CRISPR knockouts for BTBD3
- OriGene ORF clones in human for BTBD3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For BTBD3
- GenScript: Next-day shipping of latest version cDNA ORF clones for BTBD3 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for BTBD3
- GenScript Custom Assay Services for BTBD3
- GenScript Custom overexpressing Cell Line Services for BTBD3
- GenScript: Design CRISPR guide RNA sequences for BTBD3
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for BTBD3
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for BTBD3
- Novus Biologicals lysates and proteins for BTBD3
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for BTBD3
- Abcam proteins for BTBD3
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Browse Antibodies at Cloud-Clone Corp.
- Browse Proteins at Cloud-Clone Corp.
- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for BTBD3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for BTBD3
- VectorBuilder custom plasmid, inducible vectors for BTBD3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for BTBD3
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for available BTBD3 related products ranked by validation data
- antibodies-online: Search results for available BTBD3 related products ranked by validation data
- antibodies-online: Search results for available BTBD3 related products ranked by validation data
- Search GeneTex for Antibodies for BTBD3
- Search GeneTex for Proteins for BTBD3
- ViGene Biosciences adenoviral particle packaged cDNA for BTBD3 gene
- ViGene Biosciences lentiviral particle packaged cDNA for BTBD3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for BTBD3 gene
- Search ViGene Biosciences for BTBD3
- Horizon Cell Lines for BTBD3
- genomics-online: cdna clones - Search results for available BTBD3 gene related products
- orf clones - Search results for available BTBD3 gene related products
- genomics-online: gRNA clones - Search results for available BTBD3 gene related products
- genomics-online: primer clones - Search results for available BTBD3 gene related products
- genomics-online: shRNA clones - Search results for available BTBD3 gene related products
Sources for BTBD3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew