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BTBD3 Gene

protein-coding GIFtS: 50
GCID: GC20P011866

BTB (POZ) Domain Containing 3

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MalaCards

disease database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
BTB (POZ) Domain Containing 3¹ ²
KIAA0952³ ⁵
BTB/POZ Domain-Containing Protein 3²
dJ742J24.1²

External Ids:	HGNC: 15854¹	Entrez Gene: 22903²	Ensembl: ENSG00000132640⁷	OMIM: 615566⁵	UniProtKB: Q9Y2F9³

Export aliases for BTBD3 gene to outside databases

Previous GC identifers: GC20P011886 GC20P011819

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for BTBD3 Gene:

BTBD3 (BTB (POZ) domain containing 3) is a protein-coding gene. An important paralog of this gene is BTBD2.

UniProtKB/Swiss-Prot: BTBD3_HUMAN, Q9Y2F9

Function: Acts as a key regulator of dendritic field orientation during development of sensory cortex. Also

directs dendrites toward active axon terminals when ectopically expressed (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

Regulatory elements:

Regulatory transcription factor binding sites in the BTBD3 gene promoter:
E2F-4 E2F-3a E2F-5 FOXD3 E2F-2 E2F E2F-1 POU2F1 POU2F1a GR-alpha
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: BTBD3 promoter sequence

Search Chromatin IP Primers for BTBD3

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BTBD3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20p12.2 Ensembl cytogenetic band: 20p12.2 HGNC cytogenetic band: 20p12.2

BTBD3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BTBD3 gene location

GeneLoc information about chromosome 20 GeneLoc Exon Structure

GeneLoc location for GC20P011866: view genomic region (about GC identifiers)

Start:	11,871,371 bp from pter	End:	11,907,257 bp from pter
Size:	35,887 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, antibodies-online, and/or GeneTex,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

UniProtKB/Swiss-Prot: BTBD3_HUMAN, Q9Y2F9 (See protein sequence)

Recommended Name: BTB/POZ domain-containing protein 3

Size: 522 amino acids; 58420 Da

Sequence caution: Sequence=BAA76796.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;

Secondary accessions: D3DW19 Q5JY73

Alternative splicing: 2 isoforms: Q9Y2F9-1 Q9Y2F9-2

Explore the universe of human proteins at neXtProt for BTBD3: NX_Q9Y2F9

Explore proteomics data for BTBD3 at MOPED

Post-translational modifications:

Ubiquitination² at Lys315

Modification sites at PhosphoSitePlus

See BTBD3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (6 alternative transcripts):

NP_001269479.1 NP_001269480.1 NP_001269481.1 NP_001269483.1 NP_055777.1 NP_852108.2

ENSEMBL proteins:

ENSP00000254977 ENSP00000381971 ENSP00000384545 ENSP00000410502 ENSP00000404268

ENSP00000397809 ENSP00000408817 ENSP00000404582 ENSP00000367471

BTBD3 Human Recombinant Protein Products:

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	antibodies-online proteins for BTBD3 (3 products)
	antibodies-online peptides for BTBD3

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	antibodies-online kits for BTBD3 (4 products)

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GenesLikeMe)
About This Section

HGNC Gene Families:

BTBD: BTB/POZ domain containing

5 InterPro protein domains:

IPR012983 PHR

IPR000210 BTB/POZ-like

IPR011333 BTB/POZ_fold

IPR013069 BTB_POZ

IPR011705 BACK

Graphical View of Domain Structure for InterPro Entry Q9Y2F9

ProtoNet protein and cluster: Q9Y2F9

2 Blocks protein domains:

IPB000210 BTB/POZ domain

IPB012983 PHR

UniProtKB/Swiss-Prot: BTBD3_HUMAN, Q9Y2F9

Similarity: Contains 1 BACK (BTB/Kelch associated) domain

Similarity: Contains 1 BTB (POZ) domain

Find genes that share domains with BTBD3 About GenesLikeMe

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: BTBD3_HUMAN, Q9Y2F9

Function: Acts as a key regulator of dendritic field orientation during development of sensory cortex. Also

directs dendrites toward active axon terminals when ectopically expressed (By similarity)

Gene Ontology (GO): 1 molecular function term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	--	--

Find genes that share ontologies with BTBD3 About GenesLikeMe

Animal Models:

genOway: Develop your customized and physiologically relevant rodent model for BTBD3

miRNA Products:		miRTarBase miRNAs that target BTBD3: hsa-mir-148b-3p (MIRT019498), hsa-mir-181c-5p (MIRT006896), hsa-mir-148a-3p (MIRT026014), hsa-mir-130b-3p (MIRT020331), hsa-mir-125b-5p (MIRT046061), hsa-mir-19b-3p (MIRT031218), hsa-mir-26a-5p (MIRT050122), hsa-mir-181a-5p (MIRT025154), hsa-mir-21-5p (MIRT030995), hsa-mir-1227-3p (MIRT036405), hsa-mir-98-5p (MIRT027774), hsa-mir-24-3p (MIRT030584)

		Block miRNA regulation of human, mouse, rat BTBD3 using miScript Target Protectors
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In Situ Assay
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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
About This Section

Subcellular locations from UniProtKB/Swiss-Prot

BTBD3_HUMAN, Q9Y2F9: Cytoplasm, cytosol (By similarity). Nucleus (By similarity). Note=Translocates from the

cytosol to the nucleus in response to neuronal activity (By similarity)

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
cytosol	3
nucleus	2
extracellular	1
peroxisome	1

About this image

Gene Ontology (GO): 2 cellular component terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	ISS	--
GO:0005829	cytosol	ISS	--

Find genes that share ontologies with BTBD3 About GenesLikeMe

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GenesLikeMe, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
About This Section

Custom Pathway & Disease-focused RT² Profiler PCR Arrays for BTBD3
Interactions:

Search GeneGlobe Interaction Network for BTBD3

STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

4 Interacting proteins for BTBD3 (Q9Y2F9³ ENSP00000367471⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PLXNB3	Q9ULL4³, ENSP00000355378⁴	I2D: score=2 STRING: ENSP00000355378
UBC	ENSP00000344818⁴	STRING: ENSP00000344818
ZBTB16	ENSP00000338157⁴	STRING: ENSP00000338157
ELAVL1	ENSP00000385269⁴	STRING: ENSP00000385269

About this table

Gene Ontology (GO): 2 biological process terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0021987	cerebral cortex development	ISS	--
GO:0048813	dendrite morphogenesis	ISS	--

Find genes that share ontologies with BTBD3 About GenesLikeMe

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, Sets of similar genes according to GenesLikeMe)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for BTBD3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
About This Section

REFSEQ mRNAs for BTBD3 gene (8 alternative transcripts):

NM_001282550.1 NM_001282551.1 NM_001282552.2 NM_001282554.1 NM_014962.3 NM_181443.3 XM_006723550.1 XM_006723551.1

13 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000254977(uc002wny.3 uc010zrg.2 uc010zrh.2) ENST00000399006(uc002woa.3 uc010zrf.2)

ENST00000405977 ENST00000449299 ENST00000450368 ENST00000422390 ENST00000455911

ENST00000430557 ENST00000488503 ENST00000471120 ENST00000473416 ENST00000473180

ENST00000378226(uc002wnz.3)

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		Selected qRT-PCR Assays for microRNAs that regulate BTBD3 (see all 85):
		hsa-miR-323-3p hsa-miR-4272 hsa-miR-877* hsa-miR-4274 hsa-miR-3909 hsa-miR-130b hsa-miR-490-5p hsa-miR-4324

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		QuantiFast Probe-based Assays in human, mouse, rat BTBD3

Selected AceView cDNA sequences (see all 226):

BM785237 AW190294 AI082210 BP351808 AU132761 CK903919 NM_014962 BQ953571

BQ439776 AI032765 CR614620 AU137245 AA322020 BX472195 CF993989 CB961606

AA234077 BX645338 CB960524 AU137316 AA969489 AI834229 AA349342 BI759690

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for BTBD3 (see all 9) About this scheme

ExUns:	1a	·	1b	·	1c	^	2	^	3a	·	3b	·	3c	^	4	^	5	^	6a	·	6b	^	7a	·	7b	^	8	^	9a	·	9b	·	9c	·	9d	·	9e
SP1:							-		-		-		-		-												-
SP2:															-												-
SP3:																											-
SP4:							-		-		-		-		-				-		-						-
SP5:							-								-

ECgene alternative splicing isoforms for BTBD3

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GenesLikeMe, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

BTBD3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: TTAAATGCAA

About this image

BTBD3 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database
selected tissues (see all 8) fully expand


Limb (Muscoskeletal System) fully expand to see all 5 entries
Interzone Cells Stylopod Synovial Joint
Zeugopod

Neural Tube (Nervous System) fully expand to see all 3 entries
Metencephalon

Lung (Respiratory System) fully expand to see all 2 entries
Chondrocytes Tracheal Cartilage
Tracheal Cartilage

Cartilage (Muscoskeletal System) fully expand to see all 2 entries
Interzone Cells Stylopod Synovial Joint
Tracheal Cartilage

Brain (Nervous System) fully expand to see all 2 entries
Medulla Oblongata

BTBD3 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

BTBD3 Protein Expression

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In Situ
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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for BTBD3 gene from Selected species (see all 17) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Btbd3^{1 , 5}	BTB (POZ) domain containing 3^{1, 5}	90.68(n)¹ 97.7(a)¹		2 (68.28 cM)⁵ 228662¹ NM_145534.2¹ NP_663509.2¹ 138256565⁵
chicken (Gallus gallus)	Aves	BTBD3¹	BTB (POZ) domain containing 3	84.91(n) 96.15(a)		427688 XM_004935234.1 XP_004935291.1
lizard (Anolis carolinensis)	Reptilia	BTBD3⁶	BTB (POZ) domain containing 3	96(a)	1 ↔ 1	1(133379751-133421120)
African clawed frog (Xenopus laevis)	Amphibia	48056023²	--	82.65(n)		48056023
zebrafish (Danio rerio)	Actinopterygii	sbcb776²	sbcb776	75.89(n)		373155 CK353599.1
fruit fly (Drosophila melanogaster)	Insecta	CG5319³ lute¹	lute¹	68(a) (best of 2)³ 64.24(n)¹ 69.25(a)¹		90A4³ 42089¹ NM_001260220.1¹ NP_001247149.1¹

ENSEMBL Gene Tree for BTBD3 (if available)
TreeFam Gene Tree for BTBD3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68,Sets of similar genes according to GenesLikeMe)
About This Section

Paralogs for BTBD3 gene

BTBD2² BTBD1² BTBD6² BTBD19² BTBD9²

Selected SIMAP similar genes for BTBD3 using alignment to 6 protein entries: BTBD3_HUMAN (see all proteins) (see all similar genes):

DKFZp434B055 BTBD6 BTBD2 BTBD1 SPOP KLHL7

KLHL3 KLHL2 KLHL28 KLHL38 KLHL22 LZTR1

KLHL15 KLHL20 KLHL30 KLHL17 SPOPL KLHL1

Find genes that share paralogs with BTBD3 About GenesLikeMe

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section

SNP ID	Valid	Clinical significance	Chr 20 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs1625^1,2	C,F,A	--	11821099(+)	`aaggtT/Aacttt`	1	--	us2k¹ tfbs³		10		NA CSA WA EA	371
rs146321616^1,2		--	11821110(+)	`TCTTCC/TACAGA`	1	--	us2k¹		0	--	--	--	--
rs188153567^1,2		--	11821202(+)	`AATAAC/TGCAAG`	1	--	us2k¹		0	--	--	--	--
rs147457647^1,2	C	--	11821258(+)	`ACCTG-/CTGT CTGTT`	1	--	us2k¹		0	--	--	--	--
rs200797332^1,2		--	11821263(+)	`CTGTC-/TGTT TGTTT`	1	--	us2k¹		0	--	--	--	--
rs180948898^1,2		--	11821266(+)	`TCTGTC/TTGTTT`	1	--	us2k¹		0	--	--	--	--
rs139628830^1,2		--	11821278(+)	`TTTGTC/TTGTTT`	1	--	us2k¹		0	--	--	--	--
rs6033255^1,2	C,F	--	11821281(+)	`gtttgT/Cttgct`	1	--	us2k¹ tfbs³		10		NA CSA WA EA	371
rs186089815^1,2		--	11821332(+)	`AAGGTA/GTTGGC`	1	--	us2k¹		0	--	--	--	--
rs144071239^1,2		--	11821350(+)	`GTTGTA/GGAGGC`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for BTBD3 (11871371 - 11907257 bp)

Structural Variations
Database of Genomic Variants (DGV) 6 variations for BTBD3: About this table

Variant ID	Type	Subtype	PubMed ID
esv271822	CNV	Insertion	20981092
dgv168e55	CNV	Gain	17911159
nsv833921	CNV	Gain	17160897
dgv1307e1	CNV	Complex	17122850
dgv1308e1	CNV	Complex	17122850
nsv7339	OTHER	Inversion	18451855

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing BTBD3

DNA2.0 Custom Variant and Variant Library Synthesis for BTBD3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB, Sets of similar genes according to GenesLikeMe)
About This Section

OMIM gene information: 615566 OMIM disorders: --

Find genes that share disorders with BTBD3 About GenesLikeMe

Genetic Association Database (GAD): BTBD3
Human Genome Epidemiology (HuGE) Navigator: BTBD3 (2 documents)

Export disorders for BTBD3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for BTBD3 gene, integrated from 10 sources (see all 20):
(articles sorted by number of sources associating them with BTBD3)

Utopia: connect your pdf to the dynamic
world of online information

Genome-wide examination of genetic variants associated with response to platinum-based chemotherapy in patients with small-cell lung cancer. (PubMed id 20463552)^{1, 4} Wu C....Lin D. (Pharmacogenet. Genomics 2010)
The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)^{1, 2} Deloukas P....Rogers J. (Nature 2001)
Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)^{1, 2} Nagase T.... Ohara O. (DNA Res. 1999)
Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)¹ Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)¹ Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)¹ Comuzzie A.G....Butte N.F. (PLoS ONE 2012)
Target gene repression mediated by miRNAs miR-181c and miR-9 both of which are down-regulated by amyloid-I^. (PubMed id 21720722)¹ Schonrock N....GAPtz J. (J. Mol. Neurosci. 2012)
Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality. (PubMed id 21348951)¹ Parsa A....Liggett S.B. (Clin Transl Sci 2011)
A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (amp 2011)
Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels. (PubMed id 21987572)¹ Lee K.A....Doedens J.R. (J. Biol. Chem. 2011)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 22903	HGNC: 15854	AceView: BTBD3	Ensembl:ENSG00000132640	euGenes: HUgn22903
ECgene: BTBD3	H-InvDB: BTBD3

(According to HUGE)
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HUGE: KIAA0952

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for BTBD3	Pharmacogenomics, SNPs, Pathways

Intellectual Property for BTBD3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for BTBD3 gene:
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GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, GeneTex, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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BTBD3 Gene

BTB (POZ) Domain Containing 3

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BTBD3 Gene

BTB (POZ) Domain Containing 3

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for BTBD3 gene

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for BTBD3 gene

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for BTBD3 gene

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for BTBD3 gene

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for BTBD3 gene

Expression
for BTBD3 gene

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for BTBD3 gene

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for BTBD3 gene

Genomic Variants
for BTBD3 gene

Disorders / Diseases
for BTBD3 gene

Publications
for BTBD3 gene

Intellectual Property
for BTBD3 gene

Products
for BTBD3 gene