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BTBD2 Gene

protein-coding   GIFtS: 57
GCID: GC19M001985

BTB (POZ) Domain Containing 2

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
BTB (POZ) Domain Containing 21 2
BTB/POZ Domain-Containing Protein 22

External Ids:    HGNC: 155041   Entrez Gene: 556432   Ensembl: ENSG000001332437   OMIM: 6085315   UniProtKB: Q9BX703   
ORGUL members:         

Export aliases for BTBD2 gene to outside databases

Previous GC identifers: GC19M002048 GC19M001925 GC19M001936 GC19M001934 GC19M001757


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for BTBD2 Gene:
The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich
region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which
are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic
bodies. (provided by RefSeq, Jul 2008)

GeneCards Summary for BTBD2 Gene:
BTBD2 (BTB (POZ) domain containing 2) is a protein-coding gene. An important paralog of this gene is BTBD1.

Gene Wiki entry for BTBD2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NT_011295.12  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the BTBD2 gene promoter:
         AREB6   NF-1/L   NF-1   Elk-1   LCR-F1   YY1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for BTBD2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BTBD2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.3   Ensembl cytogenetic band:  19p13.3   HGNC cytogenetic band: 19p13.3

BTBD2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BTBD2 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M001985:  view genomic region     (about GC identifiers)

Start:
1,985,447 bp from pter      End:
2,034,880 bp from pter
Size:
49,434 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: BTBD2_HUMAN, Q9BX70 (See protein sequence)
Recommended Name: BTB/POZ domain-containing protein 2  
Size: 525 amino acids; 55931 Da
Subunit: Interacts with topoisomerase 1 and with TRIM5 isoform Delta
Sequence caution: Sequence=AAC16070.1; Type=Erroneous gene model prediction; Sequence=BAB55143.1; Type=Erroneous
initiation;
1 PDB 3D structure from and Proteopedia for BTBD2:
3NO8 (3D)    
Secondary accessions: O60418 O75248 Q4VBZ1 Q6IAC5 Q7Z5W0 Q96SX8 Q9NPS1 Q9NX81
Alternative splicing: 2 isoforms:  Q9BX70-1   Q9BX70-2   

Explore the universe of human proteins at neXtProt for BTBD2: NX_Q9BX70

Explore proteomics data for BTBD2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys100, Lys312
  • Modification sites at PhosphoSitePlus

  • See BTBD2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060267.2  
    ENSEMBL proteins: 
     ENSP00000255608   ENSP00000467113   ENSP00000466686  

    BTBD2 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for BTBD2

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    BTBD: BTB/POZ domain containing

    5 InterPro protein domains:
     IPR012983 PHR
     IPR000210 BTB/POZ-like
     IPR011333 BTB/POZ_fold
     IPR013069 BTB_POZ
     IPR011705 BACK

    Graphical View of Domain Structure for InterPro Entry Q9BX70

    ProtoNet protein and cluster: Q9BX70

    3 Blocks protein domains:
    IPB000210 BTB/POZ domain
    IPB011705 BTB/Kelch-associated
    IPB012983 PHR


    UniProtKB/Swiss-Prot: BTBD2_HUMAN, Q9BX70
    Similarity: Contains 1 BTB (POZ) domain


    Find genes that share domains with BTBD2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI12878161
         
    Find genes that share ontologies with BTBD2           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for BTBD2:
     Increased cell death HMECs cel 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for BTBD2
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    miRNA
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    miRTarBase miRNAs that target BTBD2:
    hsa-mir-33a-5p (MIRT028236), hsa-mir-324-5p (MIRT043194), hsa-mir-20a-5p (MIRT050544), hsa-mir-32-5p (MIRT028296), hsa-mir-335-5p (MIRT017784), hsa-mir-16-5p (MIRT051204)

    Block miRNA regulation of human, mouse, rat BTBD2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate BTBD2 (see all 9):
    hsa-miR-185* hsa-let-7a-2* hsa-miR-33a hsa-miR-544b hsa-miR-135b hsa-let-7g* hsa-miR-33b hsa-miR-143*
    SwitchGear 3'UTR luciferase reporter plasmidBTBD2 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BTBD2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    BTBD2_HUMAN, Q9BX70: Cytoplasm, P-body. Note=Cytoplasmic bodies
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000932cytoplasmic mRNA processing body IDA12878161

    Find genes that share ontologies with BTBD2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including BTBD2: 
              Ubiquitin Ligases in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for BTBD2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    Selected Interacting proteins for BTBD2 (Q9BX701, 2, 3 ENSP000002556084) via UniProtKB, MINT, STRING, and/or I2D (see all 41)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TP53P046371, 2, 3EBI-710091,EBI-366083 MINT-65379 I2D: score=5 
    DPPA4Q7L1902, 3, ENSP000003353064MINT-8254523 I2D: score=2 STRING: ENSP00000335306
    BRD7Q9NPI12, 3MINT-65392 I2D: score=5 
    C14orf1Q9UKR52, 3MINT-65393 I2D: score=5 
    CCDC90BQ9GZT62, 3MINT-65390 I2D: score=5 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for BTBD2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for BTBD2 gene: 
    NM_017797.3  

    Unigene Cluster for BTBD2:

    BTB (POZ) domain containing 2
    Hs.465543  [show with all ESTs]
    Unigene Representative Sequence: AK056818
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000592895 ENST00000589685 ENST00000255608(uc002luo.1 uc002lup.1)
    ENST00000587825 ENST00000592082 ENST00000587225 ENST00000589200 ENST00000590646
    ENST00000587742 ENST00000588395
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate BTBD2 (see all 9):
    hsa-miR-185* hsa-let-7a-2* hsa-miR-33a hsa-miR-544b hsa-miR-135b hsa-let-7g* hsa-miR-33b hsa-miR-143*
    SwitchGear 3'UTR luciferase reporter plasmidBTBD2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat BTBD2
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    GenScript: all cDNA clones in your preferred vector: BTBD2 (NM_015483)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BTBD2
    Primer
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    OriGene qPCR primer pairs and template standards for BTBD2
    OriGene qSTAR qPCR primer pairs in human, mouse for BTBD2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat BTBD2
      QuantiTect SYBR Green Assays in human, mouse, rat BTBD2
      QuantiFast Probe-based Assays in human, mouse, rat BTBD2

    Additional mRNA sequence: 

    AF355797.1 AK027481.1 AK056818.1 AK225831.1 AL360275.1 AY007116.1 BC000564.2 BC008035.2 
    BC053986.1 BC069199.1 BC094820.1 CR457230.1 

    10 DOTS entries:

    DT.115191  DT.95360692  DT.100789822  DT.100724241  DT.95360691  DT.95360690  DT.100789823  DT.121478488 
    DT.91771828  DT.95360708 

    Selected AceView cDNA sequences (see all 352):

    BF795430 BM751791 BU856965 BM742503 BU732212 AI199082 BM551250 AL360276 
    BM809544 AA235538 CF144459 BQ951420 AK056818 BG610802 BM912486 BQ941981 
    BM454507 BM563119 BQ922739 T51086 BU542409 BG759430 BQ083309 BQ949155 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for BTBD2    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10 ^ 11a · 11b
    SP1:        -                       -     -                       -                                 
    SP2:                                                              -                                 
    SP3:                                      -                       -                                 
    SP4:                                                                                                
    SP5:                                                                                                


    ECgene alternative splicing isoforms for BTBD2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    BTBD2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCCCAGATG
    BTBD2 Expression
    About this image

    BTBD2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    BTBD2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.465543
        Pathway & Disease-focused RT2 Profiler PCR Array including BTBD2: 
              Ubiquitin Ligases in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BTBD2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for BTBD2 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Btbd21 , 5 BTB (POZ) domain containing 21, 5 88.36(n)1
    97.72(a)1
      10 (39.72 cM)5
    2081981  NM_145361.21  NP_663336.21 
     806426175 
    chicken
    (Gallus gallus)
    Aves BTBD26
    BTB (POZ) domain containing 2
    93(a)
    1 ↔ 1
    28(2090321-2093906)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.26182 Xenopus laevis transcribed sequence with moderate similarity more 80.25(n)    BJ072849.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.114782 Transcribed sequence with moderate similarity to protein more 73.46(n)    57095017 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG170686
    --
    19(a)
    many ↔ many
    X(20119377-20122516)
    worm
    (Caenorhabditis elegans)
    Secernentea F38H4.73
    tag-301
    BTB (also known as BR-C/Ttk) domain.3
    tag-301
    58(a)3
    56.71(n)1
    60.47(a)1
      IV(11851206-11855056)3
    1781161  NM_069843.31  NP_502244.11 


    ENSEMBL Gene Tree for BTBD2 (if available)
    TreeFam Gene Tree for BTBD2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for BTBD2 gene
    BTBD12  BTBD62  BTBD192  BTBD32  BTBD92  
    Selected SIMAP similar genes for BTBD2 using alignment to 4 protein entries:     BTBD2_HUMAN (see all proteins) (see all similar genes):
    ZNF737    FKBP3    ZNF74    DCTN5    FAM3A    ZNF738
    AURA2    ZNF547    BTBD1    HECW1    HMGA2    LYRM4
    NSRP1    ZNF212    C4orf22    NF2    TMEM14B    UTY

    Find genes that share paralogs with BTBD2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for BTBD2 (see all 1034)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1175240581,2
    C,F--1984996(+) CACCAC/TGCGGC 1 -- ds50011Minor allele frequency- T:0.03EA 120
    rs1140356111,2
    C,F--1984998(+) CCACGC/TGGCCT 1 -- ds50011Minor allele frequency- T:0.02WA 118
    rs1894315901,2
    C--1985011(+) CTGCCA/GGGTTT 1 -- ds50010--------
    rs1436075291,2
    C--1985016(+) GGGTTC/TCTTGA 1 -- ds50010--------
    rs1814659191,2
    --1985062(+) CCAACA/GGCTTG 1 -- ds50010--------
    rs1480214401,2
    C--1985131(+) ATCCAC/TGGTCC 1 -- ds50010--------
    rs1421658271,2
    --1985180(+) ACACAC/TGTCCA 1 -- ds50010--------
    rs1460278351,2
    --1985218(+) GAGTTA/CGTTAG 1 -- ds50010--------
    rs1864317701,2
    --1985241(+) GCCCAA/GGGGGG 1 -- ds50010--------
    rs1168515641,2
    C,F--1985280(+) AGTCTC/TGACCT 1 -- ds50011Minor allele frequency- T:0.03EA 120

    HapMap Linkage Disequilibrium report for BTBD2 (1985447 - 2034880 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for BTBD2 (see all 25):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2717870CNV Deletion23290073
    esv2717869CNV Deletion23290073
    esv2661496CNV Deletion23128226
    esv2717868CNV Deletion23290073
    nsv470107CNV Loss18288195
    dgv3614n71CNV Loss21882294
    nsv910499CNV Loss21882294
    dgv3624n71CNV Loss21882294
    nsv910588CNV Loss21882294
    dgv3623n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608531    OMIM disorders: --


    Find genes that share disorders with BTBD2           About GenesLikeMe

    Genetic Association Database (GAD): BTBD2
    Human Genome Epidemiology (HuGE) Navigator: BTBD2 (1 document)

    Export disorders for BTBD2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for BTBD2 gene, integrated from 10 sources (see all 28):
    (articles sorted by number of sources associating them with BTBD2)
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    1. Characterization of BTBD1 and BTBD2, two similar BTB-domain- containing Kelch-like proteins that interact with topoisomerase I. (PubMed id 11818025)1, 2, 9 Xu L....D'Arpa P. (BMC Genomics 2002)
    2. BTBD1 and BTBD2 colocalize to cytoplasmic bodies with the RBCC/tripartite motif protein, TRIM5delta. (PubMed id 12878161)1, 2, 9 Xu L.... D'Arpa P. (Exp. Cell Res. 2003)
    3. Identification and characterization of BTBD1, a novel BTB domain containing gene on human chromosome 15q24. (PubMed id 11179693)1, 3, 9 Carim-Todd L.... Escarceller M. (Gene 2001)
    4. Gamma-radiation sensitivity and polymorphisms in RAD51L1 modulate glioma risk. (PubMed id 20610542)1, 4 Liu Y....Bondy M.L. (Carcinogenesis 2010)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (Nature 2004)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)
    10. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55643 HGNC: 15504 AceView: BTBD2 Ensembl:ENSG00000133243 euGenes: HUgn55643
    ECgene: BTBD2 H-InvDB: BTBD2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for BTBD2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for BTBD2 gene:
    Search GeneIP for patents involving BTBD2

    GeneCards and IP:
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