Free for academic non-profit institutions. Other users need a Commercial license

Aliases for BTBD19 Gene

Aliases for BTBD19 Gene

  • BTB Domain Containing 19 2 3 5
  • BTB (POZ) Domain Containing 19 2

External Ids for BTBD19 Gene

Previous GeneCards Identifiers for BTBD19 Gene

  • GC01P045048
  • GC01P045274
  • GC01P043388

Summaries for BTBD19 Gene

GeneCards Summary for BTBD19 Gene

BTBD19 (BTB Domain Containing 19) is a Protein Coding gene. An important paralog of this gene is BTBD1.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BTBD19 Gene

Genomics for BTBD19 Gene

Regulatory Elements for BTBD19 Gene

Enhancers for BTBD19 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G044924 0.9 Ensembl ENCODE 15.7 +118.3 118265 3.1 CTCF PKNOX1 SAP130 JUN RAD21 FOSL1 JUND EGR1 PBX2 ZNF512 BTBD19 UROD EIF2B3 ENSG00000232369 BEST4 ENSG00000226499 PTCH2 TCTEX1D4 PLK3 RNA5SP47
GH01G044805 1.4 ENCODE dbSUPER 9.7 +3.0 2994 10.7 MLX CREB3L1 ZFP64 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 TBX21 MEF2D RPS8 ENSG00000225721 UROD BEST4 SNORD46 SNORD38A DMAP1 BTBD19 DPH2 CCDC163
GH01G044798 1.4 ENCODE dbSUPER 9.2 -5.7 -5653 6.3 CREB3L1 ZFP64 DMAP1 FEZF1 YY1 SLC30A9 ZNF143 SP3 NFYC MEF2D RPS8 TOE1 GPBP1L1 BEST4 BTBD19 UROD MMACHC PLK3 TCTEX1D4
GH01G044830 0.8 dbSUPER 12.9 +23.6 23640 1.4 CTCF KLF1 TAL1 NFRKB ZNF384 ZIC2 RAD21 RELA TCF12 ZBTB48 BTBD19 TCTEX1D4 PLK3 RPS8 BEST4 RNU5D-1 KIF2C ENSG00000232369 EIF2B3 UROD
GH01G044834 0.7 Ensembl 12.9 +26.8 26844 0.2 HDAC1 L3MBTL2 UBTF MNT DPF2 ZKSCAN1 ARID1B ZNF335 IKZF1 NBN TCTEX1D4 BTBD19 PLK3 UROD BEST4 RNU5D-1 KIF2C EIF2B3 ENSG00000232369 PTCH2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around BTBD19 on UCSC Golden Path with GeneCards custom track

Genomic Location for BTBD19 Gene

Chromosome:
1
Start:
44,807,457 bp from pter
End:
44,815,585 bp from pter
Size:
8,129 bases
Orientation:
Plus strand

Genomic View for BTBD19 Gene

Genes around BTBD19 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BTBD19 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BTBD19 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BTBD19 Gene

Proteins for BTBD19 Gene

  • Protein details for BTBD19 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    C9JJ37-BTBDJ_HUMAN
    Recommended name:
    BTB/POZ domain-containing protein 19
    Protein Accession:
    C9JJ37
    Secondary Accessions:
    • B4E384
    • B7ZC36
    • B7ZC37

    Protein attributes for BTBD19 Gene

    Size:
    291 amino acids
    Molecular mass:
    32365 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAX15036.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAX15037.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for BTBD19 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for BTBD19 Gene

Post-translational modifications for BTBD19 Gene

No Post-translational modifications

No data available for DME Specific Peptides for BTBD19 Gene

Domains & Families for BTBD19 Gene

Gene Families for BTBD19 Gene

Protein Domains for BTBD19 Gene

Suggested Antigen Peptide Sequences for BTBD19 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with BTBD19: view

No data available for UniProtKB/Swiss-Prot for BTBD19 Gene

Function for BTBD19 Gene

Animal Model Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for BTBD19 Gene

Localization for BTBD19 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for BTBD19 gene
Compartment Confidence
extracellular 2
nucleus 2
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for BTBD19 Gene

Pathways & Interactions for BTBD19 Gene

SuperPathways for BTBD19 Gene

No Data Available

Interacting Proteins for BTBD19 Gene

Gene Ontology (GO) - Biological Process for BTBD19 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for BTBD19 Gene

Drugs & Compounds for BTBD19 Gene

No Compound Related Data Available

Transcripts for BTBD19 Gene

Unigene Clusters for BTBD19 Gene

BTB (POZ) domain containing 19:
Representative Sequences:

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for BTBD19 Gene

No ASD Table

Relevant External Links for BTBD19 Gene

GeneLoc Exon Structure for
BTBD19
ECgene alternative splicing isoforms for
BTBD19

Expression for BTBD19 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for BTBD19 Gene

NURSA nuclear receptor signaling pathways regulating expression of BTBD19 Gene:

BTBD19

SOURCE GeneReport for Unigene cluster for BTBD19 Gene:

Hs.632400
genes like me logo Genes that share expression patterns with BTBD19: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for BTBD19 Gene

Orthologs for BTBD19 Gene

This gene was present in the common ancestor of animals.

Orthologs for BTBD19 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia BTBD19 34 35
  • 98.97 (n)
mouse
(Mus musculus)
Mammalia Btbd19 35
  • 90 (a)
OneToOne
cow
(Bos Taurus)
Mammalia BTBD19 34 35
  • 88.66 (n)
rat
(Rattus norvegicus)
Mammalia LOC100361234 34
  • 84.03 (n)
dog
(Canis familiaris)
Mammalia BTBD19 35
  • 79 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia BTBD19 35
  • 50 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia BTBD19 35
  • 31 (a)
OneToOne
chicken
(Gallus gallus)
Aves BTBD19 34 35
  • 60.48 (n)
lizard
(Anolis carolinensis)
Reptilia BTBD19 35
  • 52 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia btbd19 34
  • 57.63 (n)
zebrafish
(Danio rerio)
Actinopterygii btbd3a 35
  • 14 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta CG7102 34 35
  • 43.86 (n)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP010439 34
  • 40.28 (n)
Species where no ortholog for BTBD19 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for BTBD19 Gene

ENSEMBL:
Gene Tree for BTBD19 (if available)
TreeFam:
Gene Tree for BTBD19 (if available)

Paralogs for BTBD19 Gene

Paralogs for BTBD19 Gene

genes like me logo Genes that share paralogs with BTBD19: view

Variants for BTBD19 Gene

Sequence variations from dbSNP and Humsavar for BTBD19 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000002002 -- 44,812,545(+) TTAAA(A/G)ATACA intron-variant
rs1000505513 -- 44,814,020(+) AAACG(A/G)GGATT downstream-variant-500B, utr-variant-3-prime
rs1000516764 -- 44,806,329(+) CCCGG(A/G)CACTG downstream-variant-500B, upstream-variant-2KB, reference, missense
rs1000890819 -- 44,812,299(+) TCAGG(C/T)GCAGG intron-variant
rs1001246064 -- 44,808,235(+) GAGGA(-/T)TTTCC nc-transcript-variant, upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for BTBD19 Gene

Variant ID Type Subtype PubMed ID
nsv461406 CNV loss 19166990
nsv546145 CNV loss 21841781
nsv546146 CNV loss 21841781
nsv950705 CNV deletion 24416366

Variation tolerance for BTBD19 Gene

Gene Damage Index Score: 1.58; 30.50% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for BTBD19 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
BTBD19

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BTBD19 Gene

Disorders for BTBD19 Gene

Relevant External Links for BTBD19

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
BTBD19

No disorders were found for BTBD19 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BTBD19 Gene

Publications for BTBD19 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4 64

Products for BTBD19 Gene

Sources for BTBD19 Gene

Content
Loading form....