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Aliases for BTBD16 Gene

Aliases for BTBD16 Gene

  • BTB (POZ) Domain Containing 16 2 3
  • C10orf87 3 4
  • BTB/POZ Domain-Containing Protein 16 3
  • Chromosome 10 Open Reading Frame 87 2

External Ids for BTBD16 Gene

Previous HGNC Symbols for BTBD16 Gene

  • C10orf87

Previous GeneCards Identifiers for BTBD16 Gene

  • GC10P124022
  • GC10P117661

Summaries for BTBD16 Gene

GeneCards Summary for BTBD16 Gene

BTBD16 (BTB (POZ) Domain Containing 16) is a Protein Coding gene. An important paralog of this gene is GMCL1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BTBD16 Gene

Genomics for BTBD16 Gene

Regulatory Elements for BTBD16 Gene

Genomic Location for BTBD16 Gene

122,271,296 bp from pter
122,338,162 bp from pter
66,867 bases
Plus strand

Genomic View for BTBD16 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for BTBD16 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BTBD16 Gene

Proteins for BTBD16 Gene

  • Protein details for BTBD16 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    BTB/POZ domain-containing protein 16
    Protein Accession:
    Secondary Accessions:
    • A6NM63
    • Q4VXL1
    • Q96LN0

    Protein attributes for BTBD16 Gene

    506 amino acids
    Molecular mass:
    58481 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for BTBD16 Gene


neXtProt entry for BTBD16 Gene

Proteomics data for BTBD16 Gene at MOPED

Post-translational modifications for BTBD16 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for BTBD16 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for BTBD16 Gene

Domains for BTBD16 Gene

Gene Families for BTBD16 Gene

Protein Domains for BTBD16 Gene


Suggested Antigen Peptide Sequences for BTBD16 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 BTB (POZ) domain.
  • Contains 1 BTB (POZ) domain.
genes like me logo Genes that share domains with BTBD16: view

Function for BTBD16 Gene

Phenotypes for BTBD16 Gene

GenomeRNAi human phenotypes for BTBD16:
genes like me logo Genes that share phenotypes with BTBD16: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for BTBD16

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for BTBD16 Gene

Localization for BTBD16 Gene

Subcellular locations from

Jensen Localization Image for BTBD16 Gene COMPARTMENTS Subcellular localization image for BTBD16 gene
Compartment Confidence
nucleus 2
cytosol 1
mitochondrion 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for BTBD16 Gene

Pathways for BTBD16 Gene

SuperPathways for BTBD16 Gene

No Data Available

Interacting Proteins for BTBD16 Gene

Gene Ontology (GO) - Biological Process for BTBD16 Gene


No data available for Pathways by source for BTBD16 Gene

Transcripts for BTBD16 Gene

mRNA/cDNA for BTBD16 Gene

(7) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(11) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for BTBD16 Gene

BTB (POZ) domain containing 16:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for BTBD16

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for BTBD16 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16a · 16b

Relevant External Links for BTBD16 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for BTBD16 Gene

mRNA expression in normal human tissues for BTBD16 Gene

mRNA differential expression in normal tissues according to GTEx for BTBD16 Gene

This gene is overexpressed in Bladder (13.7), Skin - Sun Exposed (Lower leg) (6.1), and Testis (5.9).

Protein differential expression in normal tissues for BTBD16 Gene

This gene is overexpressed in Stomach (27.1), Prostate (20.0), Ovary (9.8), and Testis (6.9).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for BTBD16 Gene

SOURCE GeneReport for Unigene cluster for BTBD16 Gene Hs.422466

genes like me logo Genes that share expressions with BTBD16: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Expression partners for BTBD16 Gene

Orthologs for BTBD16 Gene

This gene was present in the common ancestor of animals.

Orthologs for BTBD16 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia BTBD16 35
  • 82.16 (n)
  • 75.35 (a)
BTBD16 36
  • 75 (a)
(Canis familiaris)
Mammalia BTBD16 35
  • 83 (n)
  • 75 (a)
BTBD16 36
  • 74 (a)
(Mus musculus)
Mammalia Btbd16 35
  • 79.02 (n)
  • 70.34 (a)
Btbd16 16
Btbd16 36
  • 67 (a)
(Pan troglodytes)
Mammalia BTBD16 35
  • 98.68 (n)
  • 97.43 (a)
BTBD16 36
  • 96 (a)
(Rattus norvegicus)
Mammalia Btbd16 35
  • 78.92 (n)
  • 69.17 (a)
(Monodelphis domestica)
Mammalia BTBD16 36
  • 64 (a)
(Ornithorhynchus anatinus)
Mammalia BTBD16 36
  • 58 (a)
(Anolis carolinensis)
Reptilia BTBD16 36
  • 44 (a)
(Danio rerio)
Actinopterygii btbd16 35
  • 48.75 (n)
  • 37.38 (a)
btbd16 36
  • 29 (a)
fruit fly
(Drosophila melanogaster)
Insecta gcl 36
  • 14 (a)
(Caenorhabditis elegans)
Secernentea gcl-1 36
  • 13 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 20 (a)
Species with no ortholog for BTBD16:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for BTBD16 Gene

Gene Tree for BTBD16 (if available)
Gene Tree for BTBD16 (if available)

Paralogs for BTBD16 Gene

Paralogs for BTBD16 Gene

genes like me logo Genes that share paralogs with BTBD16: view

Variants for BTBD16 Gene

Sequence variations from dbSNP and Humsavar for BTBD16 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs911774 -- 122,286,372(-) AACAC(C/T)GTGGA intron-variant
rs911775 -- 122,285,787(-) GCTTC(A/G)TGGAA intron-variant
rs911776 -- 122,285,538(-) agcca(A/C)atcac intron-variant
rs911777 -- 122,284,718(-) GTCAC(A/G)CCATG intron-variant
rs911787 -- 122,304,795(+) tgatc(C/T)gcccg intron-variant

Relevant External Links for BTBD16 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for BTBD16 Gene

Disorders for BTBD16 Gene

Relevant External Links for BTBD16

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for BTBD16 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for BTBD16 Gene

Publications for BTBD16 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PMID: 16385451) Grupe A. … Goate A. (Am. J. Hum. Genet. 2006) 3 48
  5. Molecular genetics of successful smoking cessation: convergent genome-wide association study results. (PMID: 18519826) Uhl G.R. … Lerman C. (Arch. Gen. Psychiatry 2008) 3 48

Products for BTBD16 Gene

Sources for BTBD16 Gene

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