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BTBD11 Gene

protein-coding   GIFtS: 44
GCID: GC12P107712

BTB (POZ) Domain Containing 11

  Search for BTBD11
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
BTB (POZ) Domain Containing 111 2
BTB/POZ Domain-Containing Protein 112 3
ABTB2B2
ANK-Repeat BTB Domain Containing Protein2
Ankyrin Repeat And BTB/POZ Domain-Containing Protein BTBD112

External Ids:    HGNC: 238441   Entrez Gene: 1215512   Ensembl: ENSG000001511367   UniProtKB: A6QL633   

Export aliases for BTBD11 gene to outside databases

Previous GC identifers: GC12P106531 GC12P106216 GC12P106513 GC12P104772


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for BTBD11 Gene:
BTBD11 (BTB (POZ) domain containing 11) is a protein-coding gene. GO annotations related to this gene include protein heterodimerization activity. An important paralog of this gene is ABTB2.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NT_029419.13  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the BTBD11 gene promoter:
         GR   HFH-3   GR-beta   Pax-2   MyoD   Pax-2a   LCR-F1   FOXI1   AREB6   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBTBD11 promoter sequence
   Search Chromatin IP Primers for BTBD11

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BTBD11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q23.3   Ensembl cytogenetic band:  12q23.3   HGNC cytogenetic band: 12q24.11

BTBD11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BTBD11 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P107712:  view genomic region     (about GC identifiers)

Start:
107,712,190 bp from pter      End:
108,053,419 bp from pter
Size:
341,230 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: BTBDB_HUMAN, A6QL63 (See protein sequence)
Recommended Name: Ankyrin repeat and BTB/POZ domain-containing protein BTBD11  
Size: 1104 amino acids; 120884 Da
Sequence caution: Sequence=AAI01562.1; Type=Erroneous initiation; Sequence=AAI01564.1; Type=Erroneous initiation;
Sequence=AAI46825.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence;
Sequence=AAR21078.1; Type=Erroneous initiation; Sequence=BAC85963.1; Type=Erroneous initiation;
Sequence=EAW97799.1; Type=Erroneous gene model prediction;
Secondary accessions: A4FU41 B3KXG3 C9J019 C9JK80 E9PHS4 Q3ZTQ4 Q52M89 Q6ZV99 Q8N245
Alternative splicing: 5 isoforms:  A6QL63-1   A6QL63-2   A6QL63-3   A6QL63-4   A6QL63-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for BTBD11: NX_A6QL63

Explore proteomics data for BTBD11 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See BTBD11 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001017523.1  NP_001018082.1  

    ENSEMBL proteins: 
     ENSP00000280758   ENSP00000413889   ENSP00000447319   ENSP00000447606   ENSP00000407416  
     ENSP00000349690   ENSP00000448322  

    BTBD11 Human Recombinant Protein Products:

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    Novus Biologicals BTBD11 Protein
    Novus Biologicals BTBD11 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for BTBD11

     
    Search eBioscience for Proteins for BTBD11 

    BTBD11 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    BTBD11 Assay Products:

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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for BTBD11
    Cloud-Clone Corp. CLIAs for BTBD11
    Search eBioscience for ELISAs for BTBD11 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    BTBD: BTB/POZ domain containing
    ANKRD: Ankyrin repeat domain containing

    Selected InterPro protein domains (see all 6):
     IPR009072 Histone-fold
     IPR000210 BTB/POZ-like
     IPR002110 Ankyrin_rpt
     IPR011333 BTB/POZ_fold
     IPR013069 BTB_POZ

    Graphical View of Domain Structure for InterPro Entry A6QL63

    ProtoNet protein and cluster: A6QL63

    UniProtKB/Swiss-Prot: BTBDB_HUMAN, A6QL63
    Similarity: Contains 5 ANK repeats
    Similarity: Contains 1 BTB (POZ) domain


    Find genes that share domains with BTBD11           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BTBDB_HUMAN, A6QL63
    Induction: By all-trans retinoic acid (ATRA)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0046982protein heterodimerization activity IEA--
         
    Find genes that share ontologies with BTBD11           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for BTBD11:
     Decreased viability with pacli  Increased cell death HMECs cel  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for BTBD11
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for BTBD11
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    miRNA
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    Block miRNA regulation of human, mouse, rat BTBD11 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate BTBD11 (see all 38):
    hsa-miR-3146 hsa-miR-330-5p hsa-miR-513a-5p hsa-miR-1224-3p hsa-miR-1260b hsa-miR-374a hsa-miR-3921 hsa-miR-449a
    SwitchGear 3'UTR luciferase reporter plasmidBTBD11 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for BTBD11
    Predesigned siRNA for gene silencing in human, mouse, rat BTBD11

    Gene Editing
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    Clone
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    OriGene clones in human, mouse for BTBD11 (see all 18)
    OriGene ORF clones in mouse, rat for BTBD11
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: BTBD11 (NM_014867)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BTBD11
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat BTBD11

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BTBD11


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    BTBDB_HUMAN, A6QL63: Membrane; Single-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    mitochondrion2
    nucleus2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with BTBD11           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for BTBD11
    Interactions:

        Search GeneGlobe Interaction Network for BTBD11

    2 Interacting proteins for BTBD11 (A6QL633) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DLG3Q927963I2D: score=1 
    DLG4P783523I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for BTBD11 (BTBDB)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for BTBD11 gene (3 alternative transcripts): 
    NM_152322.2  NM_001017523.1  NM_001018072.1  

    Unigene Cluster for BTBD11:

    BTB (POZ) domain containing 11
    Hs.271272  [show with all ESTs]
    Unigene Representative Sequence: NM_001018072
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000280758(uc009zut.1 uc001tmk.1) ENST00000420571 ENST00000490090(uc001tmj.3)
    ENST00000550706 ENST00000415943 ENST00000357167(uc001tml.1 uc001tmm.1)
    ENST00000494235
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat BTBD11 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate BTBD11 (see all 38):
    hsa-miR-3146 hsa-miR-330-5p hsa-miR-513a-5p hsa-miR-1224-3p hsa-miR-1260b hsa-miR-374a hsa-miR-3921 hsa-miR-449a
    SwitchGear 3'UTR luciferase reporter plasmidBTBD11 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for BTBD11
    Predesigned siRNA for gene silencing in human, mouse, rat BTBD11
    Clone
    Products:
         
    OriGene clones in human, mouse for BTBD11 (see all 18)
    OriGene ORF clones in mouse, rat for BTBD11
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: BTBD11 (NM_014867)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BTBD11
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat BTBD11
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for BTBD11
    OriGene qSTAR qPCR primer pairs in human, mouse for BTBD11
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat BTBD11
      QuantiTect SYBR Green Assays in human, mouse, rat BTBD11
      QuantiFast Probe-based Assays in human, mouse, rat BTBD11

    Additional mRNA sequence: 

    AK091276.1 AK094304.1 AK122818.1 AK124835.1 AK127012.1 AK127295.1 AK128445.1 AY373588.1 
    BC027931.1 BC093627.1 BC093629.1 BC101561.1 BC101563.1 BC146824.1 

    6 DOTS entries:

    DT.100642931  DT.100020173  DT.95299794  DT.91722833  DT.121151225  DT.65284116 

    Selected AceView cDNA sequences (see all 56):

    AK122818 AA722861 AK127295 T32438 CB046343 AA860501 AL040935 AL040936 
    AI565114 AA883254 AW583242 AK128445 BX105006 AA782574 AK091276 BI493600 
    CD651922 BF957506 BE794809 AK127012 AW296871 AA333768 AA838670 AW583798 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    BTBD11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATCATTTGCA
    BTBD11 Expression
    About this image


    BTBD11 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Mandibular Condyle
             HyStem+TGFbeta3+GDF5-induced 7PEND24 cells
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Cerebral Cortex
     
     Lung (Respiratory System)
             Basal Cells Trachea
     
     Limb (Muscoskeletal System)
             Limb Bud Mesenchyme Cells Limb Bud
     
     Mesoderm (Gastrulation Derivatives)
             Limb Bud Mesenchyme Cells Limb Bud
    BTBD11 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    BTBD11 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.271272
        Custom PCR Arrays for BTBD11
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BTBD11

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for BTBD11 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Btbd111 , 5 BTB (POZ) domain containing 111, 5 89.86(n)1
    95.2(a)1
      10 (41.65 cM)5
    740071  NM_028709.21  NP_082985.21 
     853868145 
    chicken
    (Gallus gallus)
    Aves BTBD111 BTB (POZ) domain containing 11 83.36(n)
    93.3(a)
      771493  XM_001234770.3  XP_001234771.3 
    lizard
    (Anolis carolinensis)
    Reptilia BTBD116
    BTB (POZ) domain containing 11
    91(a)
    1 ↔ 1
    5(19650947-19797516)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.157272 Xenopus laevis transcribed sequence with weak similarity more 81.77(n)    BJ050091.1 
    zebrafish
    (Danio rerio)
    Actinopterygii btbd11b1 BTB (POZ) domain containing 11b 71.31(n)
    75.42(a)
      100034519  XM_003200435.2  XP_003200483.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG439806
    --
    23(a)
    1 → many
    3L(21638058-21659406)


    ENSEMBL Gene Tree for BTBD11 (if available)
    TreeFam Gene Tree for BTBD11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for BTBD11 gene
    ABTB22  
    1 SIMAP similar gene for BTBD11 using alignment to 3 protein entries:     BTBDB_HUMAN (see all proteins):
    ABTB2

    Find genes that share paralogs with BTBD11           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for BTBD11 (see all 6980)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1869528441,2
    --104770633(+) ATTTCA/TCTTAG 1 -- us2k10--------
    rs675246851,2
    C--104962484(+) ATGGA-/TGGA/ 
    TGGATGGA
    AGAGT
    1 -- int12NA 4
    rs1429544661,2
    C--107631364(+) TTTTT-/TAGCATG 1 -- int11Minor allele frequency- TA:0.00NA 2
    rs1914212771,2
    --107710234(+) CTGCAA/TATGAC 1 -- us2k10--------
    rs748265871,2
    C--107710414(+) GATGTC/TCTTTT 1 -- us2k10--------
    rs1134956091,2
    C--107710421(+) TTTCCT/-TTTTT 1 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs1503523351,2
    --107710468(+) CCCAGC/GCTGAG 1 -- us2k10--------
    rs1823776191,2
    --107710476(+) GAGGTG/TCAGTG 1 -- us2k10--------
    rs590135701,2
    C,F--107710491(+) AATCTG/TGGCTC 1 -- us2k12Minor allele frequency- T:0.50NA WA 4
    rs1406055871,2
    --107710494(+) CTTGGC/TTCACT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for BTBD11 (107712190 - 107962190 bp, first 250kb of BTBD11)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for BTBD11 (see all 20):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2746337CNV Deletion23290073
    esv1332246CNV Deletion17803354
    esv2025373CNV Deletion18987734
    esv2746338CNV Deletion23290073
    esv2746339CNV Deletion23290073
    esv1000854CNV Deletion20482838
    nsv874CNV Insertion18451855
    nsv872CNV Insertion18451855
    nsv876CNV Insertion18451855
    nsv524699CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing BTBD11
    DNA2.0 Custom Variant and Variant Library Synthesis for BTBD11

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with BTBD11           About GenesLikeMe

    Genetic Association Database (GAD): BTBD11
    Human Genome Epidemiology (HuGE) Navigator: BTBD11 (4 documents)

    Export disorders for BTBD11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for BTBD11 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with BTBD11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (Am. J. Hum. Genet. 2009)
    5. A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB. (PubMed id 19734545)1 Need A.C....Goldstein D.B. (Hum. Mol. Genet. 2009)
    6. Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data. (PubMed id 17362836)4 Schymick J.C....Traynor B.J. (Lancet Neurol 2007)
    7. The finished DNA sequence of human chromosome 12. (PubMed id 16541075)2 Scherer S.E.... Gibbs R.A. (Nature 2006)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 121551 HGNC: 23844 AceView: BTBD11 Ensembl:ENSG00000151136 euGenes: HUgn121551
    ECgene: BTBD11 H-InvDB: BTBD11

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for BTBD11 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for BTBD11 gene:
    Search GeneIP for patents involving BTBD11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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