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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

BTBD11 Gene

protein-coding GIFtS: 43
GCID: GC12P107712

BTB (POZ) domain containing 11

Search for BTBD11
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
BTB (POZ) Domain Containing 11¹ ²
BTB/POZ Domain-Containing Protein 11² ³
FLJ33957¹
ANK-Repeat BTB Domain Containing Protein²
Ankyrin Repeat And BTB/POZ Domain-Containing Protein BTBD11²

External Ids:	HGNC: 23844¹	Entrez Gene: 121551²	Ensembl: ENSG00000151136⁷	UniProtKB: A6QL63³

Export aliases for BTBD11 gene to outside databases

Previous GC identifers: GC12P106531 GC12P106216 GC12P106513 GC12P104772

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000012.11 NC_018923.1 NT_029419.12

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the BTBD11 gene promoter:
GR HFH-3 GR-beta Pax-2 MyoD Pax-2a LCR-F1 FOXI1 AREB6 GR-alpha
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: BTBD11 promoter sequence

Search SABiosciences Chromatin IP Primers for BTBD11

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BTBD11

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q23.3 Ensembl cytogenetic band: 12q23.3 HGNC cytogenetic band: 12q24.11

BTBD11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BTBD11 gene location

GeneLoc information about chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12P107712: view genomic region (about GC identifiers)

Start:	107,712,190 bp from pter	End:	108,053,419 bp from pter
Size:	341,230 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: BTBDB_HUMAN, A6QL63 (See protein sequence)

Recommended Name: Ankyrin repeat and BTB/POZ domain-containing protein BTBD11

Size: 1104 amino acids; 120884 Da

Subcellular location: Membrane; Single-pass membrane protein (Potential)

Sequence caution: Sequence=AAI01562.1; Type=Erroneous initiation; Sequence=AAI01564.1; Type=Erroneous initiation;

Sequence=AAI46825.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence;

Sequence=AAR21078.1; Type=Erroneous initiation; Sequence=BAC85963.1; Type=Erroneous initiation; Sequence=EAW97799.1;

Type=Erroneous gene model prediction;

Secondary accessions: A4FU41 B3KXG3 C9J019 C9JK80 E9PHS4 Q3ZTQ4 Q52M89 Q6ZV99 Q8N245

Alternative splicing: 5 isoforms: A6QL63-1 A6QL63-2 A6QL63-3 A6QL63-4 A6QL63-5 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for BTBD11: NX_A6QL63

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_A6QL63

BTBD11 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001017523.1 NP_001018082.1

ENSEMBL proteins:

ENSP00000280758 ENSP00000413889 ENSP00000447319 ENSP00000447606 ENSP00000407416

ENSP00000349690 ENSP00000448322

Human Recombinant Protein Products:

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	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate: BTBD11 OriGene Custom Protein Services for BTBD11
	GenScript Custom Purified and Recombinant Proteins Services for BTBD11
	Novus Biologicals BTBD11 Protein Novus Biologicals BTBD11 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for BTBD11

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016021	integral to membrane	IEA	--

BTBD11 for ontologies About GeneDecksing

BTBD11 Antibody Products:

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	GenScript Custom Superior Antibodies Services for BTBD11
	Search for Antibodies for BTBD11 at Abcam
	Uscn Antibodies for BTBD11
	Search ThermoFisher Antibodies for BTBD11

Assay Products for BTBD11:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for BTBD11
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for BTBD11

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

BTBD11 for domains About GeneDecksing

5/6 InterPro domains/families (see all 6):

IPR011333 BTB/POZ_fold

IPR013069 BTB_POZ

IPR020683 Ankyrin_rpt-contain_dom

IPR009072 Histone-fold

IPR000210 BTB/POZ-like

Graphical View of Domain Structure for InterPro Entry A6QL63

ProtoNet protein and cluster: A6QL63

UniProtKB/Swiss-Prot: BTBDB_HUMAN, A6QL63

Similarity: Contains 5 ANK repeats

Similarity: Contains 1 BTB (POZ) domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: BTBDB_HUMAN, A6QL63

Induction: By all-trans retinoic acid (ATRA)

miRNA Products:		OriGene 3'-UTR Clone (see all 2): BTBD11 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BTBD11
		8/38 QIAGEN miScript miRNA Assays for microRNAs that regulate BTBD11 (see all 38):
		hsa-miR-3146 hsa-miR-330-5p hsa-miR-513a-5p hsa-miR-1224-3p hsa-miR-1260b hsa-miR-374a hsa-miR-3921 hsa-miR-449a

		SwitchGear 3'UTR luciferase reporter plasmid: BTBD11 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BTBD11 (see all 7) OriGene shRNA RFP: BTBD11 OriGene siRNA: BTBD11
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BTBD11

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for BTBD11

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BTBD11 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BTBD11 (see all 3) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: BTBD11 (NM_014867)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for BTBD11
		Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat BTBD11

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for BTBD11
		Search LifeMap BioReagents cell lines for BTBD11

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BTBD11

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	--	--
GO:0046982	protein heterodimerization activity	IEA	--

BTBD11 for ontologies About GeneDecksing

3 GenomeRNAi human phenotypes for BTBD11:

Decreased viability with pacli

Increased cell death HMECs cel

Synthetic lethal with Ras

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for BTBD11

2 Interacting proteins for BTBD11 (A6QL63³) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
DLG3	Q92796³	I2D: score=1
DLG4	P78352³	I2D: score=1

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for BTBD11
Search CenterWatch for drugs/clinical trials and news about BTBD11 / BTBDB

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for BTBD11 gene (3 alternative transcripts):

NM_152322.2 NM_001017523.1 NM_001018072.1

Unigene Cluster for BTBD11:

BTB (POZ) domain containing 11

Hs.271272 [show with all ESTs]

Unigene Representative Sequence: NM_001018072

7 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000280758(uc009zut.1 uc001tmk.1) ENST00000420571 ENST00000490090(uc001tmj.3)

ENST00000550706 ENST00000415943 ENST00000357167(uc001tml.1 uc001tmm.1)

ENST00000494235

miRNA Products:		OriGene 3'-UTR Clone (see all 2): BTBD11 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BTBD11
		8/38 QIAGEN miScript miRNA Assays for microRNAs that regulate BTBD11 (see all 38):
		hsa-miR-3146 hsa-miR-330-5p hsa-miR-513a-5p hsa-miR-1224-3p hsa-miR-1260b hsa-miR-374a hsa-miR-3921 hsa-miR-449a

		SwitchGear 3'UTR luciferase reporter plasmid: BTBD11 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BTBD11 (see all 7) OriGene shRNA RFP: BTBD11 OriGene siRNA: BTBD11
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BTBD11

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BTBD11 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BTBD11 (see all 3) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: BTBD11 (NM_014867)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for BTBD11
		Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat BTBD11

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BTBD11 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat BTBD11
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BTBD11
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BTBD11

Additional cDNA sequence:

AK091276.1 AK094304.1 AK122818.1 AK124835.1 AK127012.1 AK127295.1 AK128445.1 AY373588.1

BC027931.1 BC093627.1 BC093629.1 BC101561.1 BC101563.1 BC146824.1

6 DOTS entries:

DT.100642931 DT.100020173 DT.95299794 DT.91722833 DT.121151225 DT.65284116

24/56 AceView cDNA sequences (see all 56):

AI565114 BX105006 AA860501 AK127295 AA883254 CB046343 T32438 AL040936

AW583242 AK128445 AL040935 AK122818 AA722861 BU500973 BI493600 AK127012

BE379926 AA868239 CK904990 AK094304 AA782574 BE794809 AI084364 W15573

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

BTBD11 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATCATTTGCA

About this image

BTBD11 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

4 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Limb

Limb Bud

Limb Bud Mesenchyme Cells

Mesoderm

Brain

Brain

Neural Tube

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 6 LifeMap Cells

Name

Category

PureStem™ progenitor E68 (Embryonic Progenitor Cell)

PureStem™ epithelial progenitor E164 (Embryonic Progenitor Cell)

Intermediate Mesoderm, Kidney

PureStem™ mesenchymal progenitor 7PEND24 (Embryonic Progenitor Cell)

Cartilage, Neural Crest

PureStem™ progenitor EN13 (Embryonic Progenitor Cell)

Cartilage-like cells (Differentiation of s...)

Cartilage

HyStem+TGF?3+GDF5-induced 7PEND24 cells (HyStem+TGF?3+GDF5 in...)

Bone

See BTBD11 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for BTBD11

SOURCE GeneReport for Unigene cluster: Hs.271272

SABiosciences Custom PCR Arrays for BTBD11

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BTBD11 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat BTBD11
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BTBD11
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BTBD11

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BTBD11

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for BTBD11 gene from 8/18 species (see all 18) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Btbd11^{1 , 5}	BTB (POZ) domain containing 11^{1, 5}	91.18(n)¹ 97.73(a)¹		10 (41.65 cM)⁵ 74007¹ NM_028709.2¹ NP_082985.2¹ 85386814⁵
chicken (Gallus gallus)	Aves	BTBD11¹	BTB (POZ) domain containing 11	83.22(n) 92.97(a)		771493 XM_001234770.2 XP_001234771.2
lizard (Anolis carolinensis)	Reptilia	BTBD11⁶	--	91(a)	1 ↔ 1	5(19714549-19797516)
African clawed frog (Xenopus laevis)	Amphibia	Xl.15727²	Xenopus laevis transcribed sequence with weak similarity more	81.77(n)		BJ050091.1
zebrafish (Danio rerio)	Actinopterygii	btbd11b¹	BTB (POZ) domain containing 11b	71.05(n) 75.07(a)		100034519 XM_003200435.1 XP_003200483.1
fruit fly (Drosophila melanogaster)	Insecta	CG43980⁶	--	24(a)	1 → many	3L(21638058-21659406)
thale cress (Arabidopsis thaliana)	eudicotyledons	ARIA⁶ ABAP1⁶	ARMADILLO BTB protein 1	19(a) 17(a)	many ↔ many many ↔ many	5(6507794-6512759) 5(4142958-4147091)
rice (Oryza sativa)	Liliopsida	--	ABTB1 - Armadillo repeats with a Bric-a-Brac, Tram...	19(a)	1 → many	5(19305972-19315030)

ENSEMBL Gene Tree for BTBD11 (if available)
TreeFam Gene Tree for BTBD11 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for BTBD11 gene

ABTB2²

1 SIMAP similar gene for BTBD11 using alignment to 3 protein entries: BTBDB_HUMAN (see all proteins):

ABTB2

BTBD11 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 12 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs34285662^1,2	C	--	105090076(+)	`AACAA-/CCCCCC`	1	--	int¹		1		NA	2
rs191421277^1,2		--	107710234(+)	`CTGCAA/TATGAC`	1	--	us2k¹		0	--	--	--	--
rs74826587^1,2	C	--	107710414(+)	`GATGTC/TCTTTT`	1	--	us2k¹		0	--	--	--	--
rs150352335^1,2		--	107710468(+)	`CCCAGC/GCTGAG`	1	--	us2k¹		0	--	--	--	--
rs182377619^1,2		--	107710476(+)	`GAGGTG/TCAGTG`	1	--	us2k¹		0	--	--	--	--
rs59013570^1,2	C,F,	--	107710491(+)	`AATCTG/TGGCTC`	1	--	us2k¹		2		NA WA	4
rs140605587^1,2		--	107710494(+)	`CTTGGC/TTCACT`	1	--	us2k¹		0	--	--	--	--
rs145729688^1,2		--	107710530(+)	`CAATTC/TTTGTG`	1	--	us2k¹		0	--	--	--	--
rs7969446^1,2	C,F,A,H,	--	107710586(+)	`CCTGGA/CAAATT`	1	--	us2k¹		7		NA WA CSA	18
rs187048492^1,2		--	107710635(+)	`TCTGGC/TTGGTC`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for BTBD11 (107712190 - 107962190 bp, first 250kb of BTBD11)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for BTBD11
2 Indels: 24849 11061

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BTBD11

DNA2.0 Custom Variant and Variant Library Synthesis for BTBD11

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

BTBD11 for disorders About MalaCards

BTBD11 for disorders About GeneDecksing

Human Genome Epidemiology (HuGE) Navigator: BTBD11 (4 documents)

Export disorders for BTBD11 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for BTBD11 gene integrated from 9 sources:
(articles sorted by number of sources associating them with BTBD11)

Utopia: connect your pdf to the dynamic
world of online information

Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)¹ Bailey S.D....Anand S. (2010)
Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)¹ Talmud P.J.... . (2009)
A genome-wide study of common SNPs and CNVs in cognit ive performance in the CANTAB. (PubMed id 19734545)¹ Need A.C....Goldstein D.B. (2009)
The finished DNA sequence of human chromosome 12. (PubMed id 16541075)² Scherer S.E.... Gibbs R.A. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 121551	HGNC: 23844	AceView: BTBD11	Ensembl:ENSG00000151136	euGenes: HUgn121551
ECgene: BTBD11	H-InvDB: BTBD11

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for BTBD11	Pharmacogenomics, SNPs, Pathways

Intellectual Property for BTBD11 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for BTBD11 gene:
Search GeneIP for patents involving BTBD11

GeneCards and IP:
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GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
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The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

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Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

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BTBD11 Gene

BTB (POZ) domain containing 11

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BTBD11 Gene

BTB (POZ) domain containing 11

Aliasesfor BTBD11 gene

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