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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

BTAF1 Gene

protein-coding   GIFtS: 60
GCID: GC10P093673

BTAF1 RNA Polymerase II, B-TFIID Transcription Factor-Associated,...

(Previous names: BTAF1 RNA polymerase II, B-TFIID transcription factor-associated,...)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
BTAF1 RNA Polymerase II, B-TFIID Transcription Factor-Associated,
170kDa1 2
     BTAF1 RNA Polymerase II, B-TFIID Transcription Factor-Associated, 170 KD
(Mot1 Homolog, S. Cerevisiae)1
TAF1722 3 5     Mot1 Homolog (S. Cerevisiae)1
TAF(II)1702 3     BTAF1 RNA Polymerase II, B-TFIID Transcription Factor-Associated, 170kDa
(Mot1 Homolog, S. Cerevisiae)2
ATP-Dependent Helicase BTAF12 3     Mot1 Homolog2
B-TFIID Transcription Factor-Associated 170 KDa Subunit2 3     TATA-Binding Protein-Associated Factor 1722
TBP-Associated Factor 1722 3     EC 3.6.4.-3
MOT12 5     TAF-1723
TAFII1702 5     EC 3.6.18

External Ids:    HGNC: 173071   Entrez Gene: 90442   Ensembl: ENSG000000955647   OMIM: 6051915   UniProtKB: O149813   

Export aliases for BTAF1 gene to outside databases

Previous GC identifers: GC10P092564 GC10P092905 GC10P093814 GC10P093348 GC10P093338 GC10P087312


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for BTAF1 Gene:
This gene encodes a TAF (TATA box-binding protein-associated factor), which associates with TBP (TATA box-binding
protein) to form the B-TFIID complex that is required for transcription initiation of genes by RNA polymerase II.
This TAF has DNA-dependent ATPase activity, which drives the dissociation of TBP from DNA, freeing the TBP to
associate with other TATA boxes or TATA-less promoters. (provided by RefSeq, Sep 2011)

GeneCards Summary for BTAF1 Gene: 
BTAF1 (BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa) is a protein-coding gene. Diseases associated with BTAF1 include uv sensitive syndrome, and cone-rod dystrophy. GO annotations related to this gene include helicase activity and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZRANB3.

UniProtKB/Swiss-Prot: BTAF1_HUMAN, O14981
Function: Regulates transcription in association with TATA binding protein (TBP). Removes TBP from the TATA box in
an ATP-dependent manner

Gene Wiki entry for BTAF1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NT_030059.13  NC_018921.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the BTAF1 gene promoter:
         MEF-2A   TBP   Sox5   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   aMEF-2   POU3F2   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBTAF1 promoter sequence
   Search SABiosciences Chromatin IP Primers for BTAF1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BTAF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q22-q23   Ensembl cytogenetic band:  10q23.32   HGNC cytogenetic band: 10q22-q23

BTAF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BTAF1 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P093673:  view genomic region     (about GC identifiers)

Start:
93,683,526 bp from pter      End:
93,790,082 bp from pter
Size:
106,557 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: BTAF1_HUMAN, O14981 (See protein sequence)
Recommended Name: TATA-binding protein-associated factor 172  
Size: 1849 amino acids; 206887 Da
Subunit: Associates with TBP to form B-TFIID. Binds DRAP1
Subcellular location: Nucleus
Secondary accessions: O43578

Explore the universe of human proteins at neXtProt for BTAF1: NX_O14981

Explore proteomics data for BTAF1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O14981

  • 4 DME Specific Peptides for BTAF1 (O14981)
     MGLGKTL  RAHRIGQ  QAMDRAHR  NLTGADTV 

    BTAF1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    BTAF1 Protein Expression
    REFSEQ proteins: NP_003963.1  
    ENSEMBL proteins: 
     ENSP00000265990   ENSP00000439924  

    Human Recombinant Protein Products for BTAF1: 
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    Cloud-Clone Corp. Proteins for BTAF1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus NAS--

    BTAF1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5/7 InterPro protein domains (see all 7):
     IPR011989 ARM-like
     IPR027417 P-loop_NTPase
     IPR022707 DUF3535
     IPR000330 SNF2_N
     IPR014001 Helicase_ATP-bd

    Graphical View of Domain Structure for InterPro Entry O14981

    ProtoNet protein and cluster: O14981

    2 Blocks protein domains:
    IPB000330 SNF2 related domain
    IPB000357 HEAT repeat


    UniProtKB/Swiss-Prot: BTAF1_HUMAN, O14981
    Similarity: Belongs to the SNF2/RAD54 helicase family
    Similarity: Contains 8 HEAT repeats
    Similarity: Contains 1 helicase ATP-binding domain
    Similarity: Contains 1 helicase C-terminal domain


    BTAF1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BTAF1_HUMAN, O14981
    Function: Regulates transcription in association with TATA binding protein (TBP). Removes TBP from the TATA box in
    an ATP-dependent manner

         Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.-1

         Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity NAS9342322
    GO:0004386helicase activity IEA--
    GO:0005488binding ----
         
    BTAF1 for ontologies           About GeneDecksing


    Phenotypes:
         7 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Btaf1):
     cardiovascular system  craniofacial  embryogenesis  growth/size  homeostasis/metabolism 
     muscle  nervous system 

    BTAF1 for phenotypes           About GeneDecksing

    Animal Models:
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    SwitchGear 3'UTR luciferase reporter plasmidBTAF1 3' UTR sequence
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BTAF1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for BTAF1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Chromatin Regulation / Acetylation
    Chromatin Regulation / Acetylation

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for BTAF1
        Chromatin Regulation / Acetylation



    BTAF1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for BTAF1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/889 Interacting proteins for BTAF1 (O149812, 3 ENSP000002659904) via UniProtKB, MINT, STRING, and/or I2D (see all 889)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053, ENSP000003529804I2D: score=3 STRING: ENSP00000352980
    HIST1H4CP628053, ENSP000003670344I2D: score=3 STRING: ENSP00000367034
    HIST1H4DP628053, ENSP000003432824I2D: score=3 STRING: ENSP00000343282
    HIST1H4EP628053, ENSP000003536244I2D: score=3 STRING: ENSP00000353624
    HIST1H4HP628053, ENSP000002893524I2D: score=3 STRING: ENSP00000289352
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0045892negative regulation of transcription, DNA-dependent NAS9488487

    BTAF1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    BTAF1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for BTAF1

    1 Novoseek inferred chemical compound relationship for BTAF1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    atp 33.9 11 9488487 (3), 15509807 (2), 16541100 (2), 15861138 (1)

    Search CenterWatch for drugs/clinical trials and news about BTAF1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for BTAF1 gene: 
    NM_003972.2  

    Unigene Cluster for BTAF1:

    BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae)
    Hs.500526  [show with all ESTs]
    Unigene Representative Sequence: NM_003972
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000265990(uc009xua.1 uc001khr.3 uc001khs.1 uc001kht.1)
    ENST00000471217 ENST00000476401 ENST00000544642
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    8/37 QIAGEN miScript miRNA Assays for microRNAs that regulate BTAF1 (see all 37):
    hsa-miR-4291 hsa-miR-15a hsa-miR-3074-3p hsa-miR-374c hsa-miR-1184 hsa-miR-424 hsa-miR-3613-3p hsa-miR-23a
    SwitchGear 3'UTR luciferase reporter plasmidBTAF1 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AB208843.1 AF038362.1 AJ001017.2 AK303554.1 AK308399.1 BC029930.1 BC030273.1 BC047009.2 
    BC112201.1 

    6 DOTS entries:

    DT.413677  DT.101976065  DT.102824771  DT.99967068  DT.65284704  DT.75151467 

    24/152 AceView cDNA sequences (see all 152):

    AA278702 CK906077 AL157602 AW008507 AA640075 AA970986 BG739831 AU117817 
    CK906078 AA278244 AA470008 CR621419 AJ001017 BC029930 AV703067 AA648929 
    CA394387 BM768786 AI634270 AA295518 BC047009 AI540658 BG315231 BM127439 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for BTAF1 (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16a · 16b ^ 17 ^ 18a ·
    SP1:              -     -                                                                       -                                                               
    SP2:                                                                                                                                                            
    SP3:                                                              -                                                                                             
    SP4:                                                                                                                                                            
    SP5:              -                                                                                                                                             

    ExUns: 18b ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30 ^ 31 ^ 32 ^ 33 ^ 34 ^ 35 ^ 36 ^ 37 ^ 38 ^ 39 ^ 40a · 40b
    SP1:  -                                               -                                                                                             
    SP2:  -                                                                                                                                             
    SP3:                                                                                                                                                
    SP4:                                                                                                                                                
    SP5:                                                                                                                                                


    ECgene alternative splicing isoforms for BTAF1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    BTAF1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCTGTGTGCA
    BTAF1 Expression
    About this image


    See BTAF1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for BTAF1

    SOURCE GeneReport for Unigene cluster: Hs.500526
        SABiosciences Custom PCR Arrays for BTAF1
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for BTAF1 gene from 9/24 species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Btaf11 , 5 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, more1, 5 91.45(n)1
    96.32(a)1
      19 (32.02 cM)5
    1071821  NM_001080706.11  NP_001074175.11 
     369260795 
    chicken
    (Gallus gallus)
    Aves BTAF11 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, more 82.05(n)
    90.15(a)
      423817  XM_421689.3  XP_421689.2 
    lizard
    (Anolis carolinensis)
    Reptilia BTAF16
    BTAF1 RNA polymerase II, B-TFIID transcription fac...
    87(a)
    1 ↔ 1
    GL343262.1(1610783-1681642)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.38822 Xenopus laevis transcribed sequence with moderate similarity more 77.41(n)    BX843554.1 
    zebrafish
    (Danio rerio)
    Actinopterygii btaf12 Transcribed sequence with moderate similarity to protein more 73.58(n)    57061562 
    fruit fly
    (Drosophila melanogaster)
    Insecta Hel89B1 , 3 helicase3
    Helicase 89B1
    58(a)3
    52.47(n)1
    49.69(a)1
      419431  NM_169693.21  NP_732097.21 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes MOT1(YPL082C)4
    MOT11
    Essential abundant protein involved in regulation of more4
    Mot1p1
    49.86(n)1
    40.6(a)1
      16(404083-398480)4
    8560231, 4  NP_015243.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons RGD31 TATA box binding protein associated factor-like protein 51.71(n)
    45.03(a)
      824595  NM_115288.7  NP_190996.3 
    barley
    (Hordeum vulgare)
    Liliopsida Hv.88742 Transcribed sequence with weak similarity to protein more 68.77(n)    BQ470329.1 


    ENSEMBL Gene Tree for BTAF1 (if available)
    TreeFam Gene Tree for BTAF1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for BTAF1 gene
    ZRANB32  SMARCAL12  
    6 SIMAP similar genes for BTAF1 using alignment to 6 protein entries:     BTAF1_HUMAN (see all proteins):
    SHPRH    ERCC6    SMARCA2    SMARCA5    ATRX    HELLS

    BTAF1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2081 SNPs in BTAF1 are shown (see all 2081)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs3688195091,2
    C--87338663(+) TTTGT-/GTTG  
            
    GGGGG
    1 -- int10--------
    rs111867491,2
    C,F,H--93681898(+) GTCTCT/CCATAT 1 -- us2k19Minor allele frequency- C:0.25NS EA NA WA 744
    rs111867501,2
    C,H--93681994(+) GATGAG/AGCAAG 1 -- us2k14Minor allele frequency- A:0.00NS EA 412
    rs573398461,2
    C,F--93682026(+) TAAAGA/TTATCT 1 -- us2k12Minor allele frequency- T:0.07WA 120
    rs1404991061,2
    C--93682071(+) ACACCA/GCCAAG 1 -- us2k10--------
    rs111867511,2
    C,F--93682189(+) gtttcC/Tttgtc 1 -- us2k18Minor allele frequency- T:0.25NA WA EA 504
    rs741493161,2
    C,F--93682197(+) GTCTAC/TGAAGA 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1383088251,2
    --93682428(+) AGACTC/GAAGGA 1 -- us2k10--------
    rs1438182201,2
    --93682555(+) GGGCTG/TAACTG 1 -- us2k10--------
    rs1861941991,2
    --93682565(+) GAAAAC/TTGGAG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for BTAF1 (93683526 - 93790082 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for BTAF1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv895893CNV Gain21882294


    Human Gene Mutation Database (HGMD): BTAF1
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing BTAF1
    DNA2.0 Custom Variant and Variant Library Synthesis for BTAF1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 605191    OMIM disorders: --

    8 diseases for BTAF1:    About MalaCards
    uv sensitive syndrome    cone-rod dystrophy    macular degeneration    age related macular degeneration
    pneumonia    tuberculosis    alzheimer's disease    breast cancer


    BTAF1 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): BTAF1
    Human Genome Epidemiology (HuGE) Navigator: BTAF1 (2 documents)

    Export disorders for BTAF1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for BTAF1 gene, integrated from 9 sources (see all 41):
    (articles sorted by number of sources associating them with BTAF1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and biochemical characterization of TAF-172, a human homolog of yeast Mot1. (PubMed id 9488487)1, 2, 3, 9 Chicca J.J. II... Pugh B.F. (1998)
    2. Cloning of the cDNA for the TATA-binding protein-associated factorII170 subunit of transcription factor B-TFIID reveals homology to global transcription regulators in yeast and Drosophila. (PubMed id 9342322)1, 2, 3, 9 van der Knaap J.A....Timmers H.T.M. (1997)
    3. NC2alpha interacts with BTAF1 and stimulates its ATP-dependent association with TATA-binding protein. (PubMed id 15509807)1, 2, 9 Klejman M.P.... Timmers H.T.M. (2004)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    5. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (2006)
    6. The gene for human TATA-binding-protein-associated factor (TAFII) 170: structure, promoter and chromosomal localization. (PubMed id 10642510)1, 2 Van Der Knaap J.A.... Timmers H.T.M. (2000)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9044 HGNC: 17307 AceView: BTAF1 Ensembl:ENSG00000095564 euGenes: HUgn9044
    ECgene: BTAF1 H-InvDB: BTAF1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for BTAF1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for BTAF1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for BTAF1 gene:
    Search GeneIP for patents involving BTAF1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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