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BTAF1 Gene

protein-coding   GIFtS: 61
GCID: GC10P093673

BTAF1 RNA Polymerase II, B-TFIID Transcription Factor-Associated,...

(Previous names: BTAF1 RNA polymerase II, B-TFIID transcription factor-associated,...)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
BTAF1 RNA Polymerase II, B-TFIID Transcription Factor-Associated,
170kDa1 2
     BTAF1 RNA Polymerase II, B-TFIID Transcription Factor-Associated, 170 KD
(Mot1 Homolog, S. Cerevisiae)1
TAF1722 3 5     Mot1 Homolog (S. Cerevisiae)1
TAF(II)1702 3     BTAF1 RNA Polymerase II, B-TFIID Transcription Factor-Associated, 170kDa
(Mot1 Homolog, S. Cerevisiae)2
ATP-Dependent Helicase BTAF12 3     Mot1 Homolog2
B-TFIID Transcription Factor-Associated 170 KDa Subunit2 3     TATA-Binding Protein-Associated Factor 1722
TBP-Associated Factor 1722 3     EC 3.6.4.-3
MOT12 5     TAF-1723
TAFII1702 5     EC 3.6.18

External Ids:    HGNC: 173071   Entrez Gene: 90442   Ensembl: ENSG000000955647   OMIM: 6051915   UniProtKB: O149813   

Export aliases for BTAF1 gene to outside databases

Previous GC identifers: GC10P092564 GC10P092905 GC10P093814 GC10P093348 GC10P093338 GC10P087312


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for BTAF1 Gene:
This gene encodes a TAF (TATA box-binding protein-associated factor), which associates with TBP (TATA box-binding
protein) to form the B-TFIID complex that is required for transcription initiation of genes by RNA polymerase II.
This TAF has DNA-dependent ATPase activity, which drives the dissociation of TBP from DNA, freeing the TBP to
associate with other TATA boxes or TATA-less promoters. (provided by RefSeq, Sep 2011)

GeneCards Summary for BTAF1 Gene:
BTAF1 (BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa) is a protein-coding gene. GO annotations related to this gene include helicase activity and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZRANB3.

UniProtKB/Swiss-Prot: BTAF1_HUMAN, O14981
Function: Regulates transcription in association with TATA binding protein (TBP). Removes TBP from the TATA box in
an ATP-dependent manner

Gene Wiki entry for BTAF1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NT_030059.14  NC_018921.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the BTAF1 gene promoter:
         MEF-2A   TBP   Sox5   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   aMEF-2   POU3F2   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBTAF1 promoter sequence
   Search Chromatin IP Primers for BTAF1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BTAF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q22-q23   Ensembl cytogenetic band:  10q23.32   HGNC cytogenetic band: 10q22-q23

BTAF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BTAF1 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P093673:  view genomic region     (about GC identifiers)

Start:
93,683,526 bp from pter      End:
93,790,082 bp from pter
Size:
106,557 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: BTAF1_HUMAN, O14981 (See protein sequence)
Recommended Name: TATA-binding protein-associated factor 172  
Size: 1849 amino acids; 206887 Da
Subunit: Associates with TBP to form B-TFIID. Binds DRAP1
Secondary accessions: O43578

Explore the universe of human proteins at neXtProt for BTAF1: NX_O14981

Explore proteomics data for BTAF1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys430
  • Modification sites at PhosphoSitePlus
  • 4 DME Specific Peptides for BTAF1 (O14981)
     MGLGKTL  RAHRIGQ  QAMDRAHR  NLTGADTV 


    See BTAF1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_003963.1  
    ENSEMBL proteins: 
     ENSP00000265990   ENSP00000439924  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    Selected InterPro protein domains (see all 7):
     IPR011989 ARM-like
     IPR022707 DUF3535
     IPR000330 SNF2_N
     IPR027417 P-loop_NTPase
     IPR014001 Helicase_ATP-bd

    Graphical View of Domain Structure for InterPro Entry O14981

    ProtoNet protein and cluster: O14981

    2 Blocks protein domains:
    IPB000330 SNF2 related domain
    IPB000357 HEAT repeat


    UniProtKB/Swiss-Prot: BTAF1_HUMAN, O14981
    Similarity: Belongs to the SNF2/RAD54 helicase family
    Similarity: Contains 8 HEAT repeats
    Similarity: Contains 1 helicase ATP-binding domain
    Similarity: Contains 1 helicase C-terminal domain


    Find genes that share domains with BTAF1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BTAF1_HUMAN, O14981
    Function: Regulates transcription in association with TATA binding protein (TBP). Removes TBP from the TATA box in
    an ATP-dependent manner

         Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.-1

         Gene Ontology (GO): Selected molecular function terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity NAS9342322
    GO:0004386helicase activity IEA--
    GO:0005488binding ----
         
    Find genes that share ontologies with BTAF1           About GenesLikeMe


    Phenotypes:
         7 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Btaf1):
     cardiovascular system  craniofacial  embryogenesis  growth/size/body  homeostasis/metabolism 
     muscle  nervous system 

    Find genes that share phenotypes with BTAF1           About GenesLikeMe

    Animal Models:
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    Selected qRT-PCR Assays for microRNAs that regulate BTAF1 (see all 37):
    hsa-miR-4291 hsa-miR-15a hsa-miR-3074-3p hsa-miR-374c hsa-miR-1184 hsa-miR-424 hsa-miR-3613-3p hsa-miR-23a
    SwitchGear 3'UTR luciferase reporter plasmidBTAF1 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    BTAF1_HUMAN, O14981: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    plasma membrane3
    cytosol1
    peroxisome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    Find genes that share ontologies with BTAF1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for BTAF1 About    
    See pathways by source

    SuperPathContained pathways About
    1Chromatin Regulation / Acetylation
    Chromatin Regulation / Acetylation


    Find genes that share SuperPaths with BTAF1           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for BTAF1
        Chromatin Regulation / Acetylation


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for BTAF1
    Interactions:

        GeneGlobe Interaction Network for BTAF1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for BTAF1 (O149812, 3 ENSP000002659904) via UniProtKB, MINT, STRING, and/or I2D (see all 1039)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053, ENSP000003529804I2D: score=3 STRING: ENSP00000352980
    HIST1H4CP628053, ENSP000003670344I2D: score=3 STRING: ENSP00000367034
    HIST1H4DP628053, ENSP000003432824I2D: score=3 STRING: ENSP00000343282
    HIST1H4EP628053, ENSP000003536244I2D: score=3 STRING: ENSP00000353624
    HIST1H4HP628053, ENSP000002893524I2D: score=3 STRING: ENSP00000289352
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0045892negative regulation of transcription, DNA-templated NAS9488487

    Find genes that share ontologies with BTAF1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for BTAF1

    1 Novoseek inferred chemical compound relationship for BTAF1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    atp 33.9 11 9488487 (3), 15509807 (2), 16541100 (2), 15861138 (1)



    Find genes that share compounds with BTAF1           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for BTAF1 gene: 
    NM_003972.2  

    Unigene Cluster for BTAF1:

    BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae)
    Hs.500526  [show with all ESTs]
    Unigene Representative Sequence: NM_003972
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000265990(uc009xua.1 uc001khr.3 uc001khs.1 uc001kht.1)
    ENST00000471217 ENST00000476401 ENST00000544642
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate BTAF1 (see all 37):
    hsa-miR-4291 hsa-miR-15a hsa-miR-3074-3p hsa-miR-374c hsa-miR-1184 hsa-miR-424 hsa-miR-3613-3p hsa-miR-23a
    SwitchGear 3'UTR luciferase reporter plasmidBTAF1 3' UTR sequence
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      QuantiFast Probe-based Assays in human, mouse, rat BTAF1

    Additional mRNA sequence: 

    AB208843.1 AF038362.1 AJ001017.2 AK303554.1 AK308399.1 BC029930.1 BC030273.1 BC047009.2 
    BC112201.1 

    6 DOTS entries:

    DT.413677  DT.101976065  DT.102824771  DT.99967068  DT.65284704  DT.75151467 

    Selected AceView cDNA sequences (see all 152):

    AA278702 CK906077 AL157602 AW008507 AA640075 AA970986 BG739831 AU117817 
    CK906078 AA278244 AA470008 CR621419 AJ001017 BC029930 AV703067 AA648929 
    CA394387 BM768786 AI634270 AA295518 BC047009 AI540658 BG315231 BM127439 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for BTAF1 (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16a · 16b ^ 17 ^ 18a ·
    SP1:              -     -                                                                       -                                                               
    SP2:                                                                                                                                                            
    SP3:                                                              -                                                                                             
    SP4:                                                                                                                                                            
    SP5:              -                                                                                                                                             

    ExUns: 18b ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30 ^ 31 ^ 32 ^ 33 ^ 34 ^ 35 ^ 36 ^ 37 ^ 38 ^ 39 ^ 40a · 40b
    SP1:  -                                               -                                                                                             
    SP2:  -                                                                                                                                             
    SP3:                                                                                                                                                
    SP4:                                                                                                                                                
    SP5:                                                                                                                                                


    ECgene alternative splicing isoforms for BTAF1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    BTAF1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCTGTGTGCA
    BTAF1 Expression
    About this image

    BTAF1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    BTAF1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.500526
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BTAF1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for BTAF1 gene from Selected species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Btaf11 , 5 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, more1, 5 91.45(n)1
    96.32(a)1
      19 (32.02 cM)5
    1071821  NM_001080706.11  NP_001074175.11 
     369260795 
    chicken
    (Gallus gallus)
    Aves BTAF11 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, more 82.06(n)
    90.15(a)
      423817  XM_421689.4  XP_421689.3 
    lizard
    (Anolis carolinensis)
    Reptilia BTAF16
    BTAF1 RNA polymerase II, B-TFIID transcription fac...
    87(a)
    1 ↔ 1
    GL343262.1(1610783-1681642)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.38822 Xenopus laevis transcribed sequence with moderate similarity more 77.41(n)    BX843554.1 
    zebrafish
    (Danio rerio)
    Actinopterygii btaf12 Transcribed sequence with moderate similarity to protein more 73.58(n)    57061562 
    fruit fly
    (Drosophila melanogaster)
    Insecta Hel89B1 , 3 helicase3
    Helicase 89B1
    58(a)3
    52.39(n)1
    49.83(a)1
      419431  NM_169693.21  NP_732097.21 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes MOT1(YPL082C)4
    MOT11
    Essential abundant protein involved in regulation of more4
    MOT11
    50.71(n)1
    41.65(a)1
      16(404083-398480)4
    8560231, 4  NP_015243.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons RGD31 RGD3 51.58(n)
    45.26(a)
      824595  NM_115288.7  NP_190996.3 
    barley
    (Hordeum vulgare)
    Liliopsida Hv.88742 Transcribed sequence with weak similarity to protein more 68.77(n)    BQ470329.1 


    ENSEMBL Gene Tree for BTAF1 (if available)
    TreeFam Gene Tree for BTAF1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for BTAF1 gene
    ZRANB32  SMARCAL12  
    6 SIMAP similar genes for BTAF1 using alignment to 6 protein entries:     BTAF1_HUMAN (see all proteins):
    SHPRH    ERCC6    SMARCA2    SMARCA5    ATRX    HELLS

    Find genes that share paralogs with BTAF1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for BTAF1 (see all 2081)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs3688195091,2
    C--87338663(+) TTTGT-/GTTG  
            
    GGGGG
    1 -- int10--------
    rs111867491,2
    C,F,H--93681898(+) GTCTCT/CCATAT 1 -- us2k19Minor allele frequency- C:0.25NS EA NA WA 744
    rs111867501,2
    C,H--93681994(+) GATGAG/AGCAAG 1 -- us2k14Minor allele frequency- A:0.00NS EA 412
    rs573398461,2
    C,F--93682026(+) TAAAGA/TTATCT 1 -- us2k12Minor allele frequency- T:0.07WA 120
    rs1404991061,2
    C--93682071(+) ACACCA/GCCAAG 1 -- us2k10--------
    rs111867511,2
    C,F--93682189(+) gtttcC/Tttgtc 1 -- us2k18Minor allele frequency- T:0.25NA WA EA 504
    rs741493161,2
    C,F--93682197(+) GTCTAC/TGAAGA 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1383088251,2
    --93682428(+) AGACTC/GAAGGA 1 -- us2k10--------
    rs1438182201,2
    --93682555(+) GGGCTG/TAACTG 1 -- us2k10--------
    rs1861941991,2
    --93682565(+) GAAAAC/TTGGAG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for BTAF1 (93683526 - 93790082 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for BTAF1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv895893CNV Gain21882294

    Human Gene Mutation Database (HGMD): BTAF1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing BTAF1
    DNA2.0 Custom Variant and Variant Library Synthesis for BTAF1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605191    OMIM disorders: --


    Find genes that share disorders with BTAF1           About GenesLikeMe

    Genetic Association Database (GAD): BTAF1
    Human Genome Epidemiology (HuGE) Navigator: BTAF1 (2 documents)

    Export disorders for BTAF1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for BTAF1 gene, integrated from 10 sources (see all 41):
    (articles sorted by number of sources associating them with BTAF1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and biochemical characterization of TAF-172, a human homolog of yeast Mot1. (PubMed id 9488487)1, 2, 3, 9 Chicca J.J. II... Pugh B.F. (Mol. Cell. Biol. 1998)
    2. Cloning of the cDNA for the TATA-binding protein-associated factorII170 subunit of transcription factor B-TFIID reveals homology to global transcription regulators in yeast and Drosophila. (PubMed id 9342322)1, 2, 3, 9 van der Knaap J.A....Timmers H.T.M. (Proc. Natl. Acad. Sci. U.S.A. 1997)
    3. NC2alpha interacts with BTAF1 and stimulates its ATP-dependent association with TATA-binding protein. (PubMed id 15509807)1, 2, 9 Klejman M.P.... Timmers H.T.M. (Mol. Cell. Biol. 2004)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    5. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    6. The gene for human TATA-binding-protein-associated factor (TAFII) 170: structure, promoter and chromosomal localization. (PubMed id 10642510)1, 2 Van Der Knaap J.A.... Timmers H.T.M. (Biochem. J. 2000)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    9. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    10. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9044 HGNC: 17307 AceView: BTAF1 Ensembl:ENSG00000095564 euGenes: HUgn9044
    ECgene: BTAF1 H-InvDB: BTAF1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for BTAF1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for BTAF1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for BTAF1 gene:
    Search GeneIP for patents involving BTAF1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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