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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

BSN Gene

protein-coding   GIFtS: 51
GCID: GC03P049591

Bassoon Presynaptic Cytomatrix Protein

(Previous name: bassoon (presynaptic cytomatrix protein))
(Previous symbol: ZNF231)
Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Bassoon Presynaptic Cytomatrix Protein1 2     Neuronal Double Zinc Finger Protein1 2
ZNF2311 2 3 5     Protein Bassoon2
Zinc Finger Protein 2311 2 3     KIAA04343
Bassoon (Presynaptic Cytomatrix Protein)1 2     

External Ids:    HGNC: 11171   Entrez Gene: 89272   Ensembl: ENSG000001640617   OMIM: 6040205   UniProtKB: Q9UPA53   

Export aliases for BSN gene to outside databases

Previous GC identifers: GC03P046613 GC03M048695 GC03P049447 GC03P049550 GC03P049566


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for BSN Gene:
Neurotransmitters are released from a specific site in the axon terminal called the active zone, which is composed
of synaptic vesicles and a meshwork of cytoskeleton underlying the plasma membrane. The protein encoded by this
gene is thought to be a scaffolding protein involved in organizing the presynaptic cytoskeleton. The gene is
expressed primarily in neurons in the brain. A similar gene product in rodents is concentrated in the active zone
of axon terminals and tightly associated with cytoskeletal structures, and is essential for regulating
neurotransmitter release from a subset of synapses. (provided by RefSeq, Jul 2008)

GeneCards Summary for BSN Gene: 
BSN (bassoon presynaptic cytomatrix protein) is a protein-coding gene. Diseases associated with BSN include decubitus ulcer, and crohn's disease. GO annotations related to this gene include metal ion binding. An important paralog of this gene is PCLO.

UniProtKB/Swiss-Prot: BSN_HUMAN, Q9UPA5
Function: Is thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ)
which regulates neurotransmitter release. Seems to act through binding to ERC2/CAST1. Essential in regulated
neurotransmitter release from a subset of brain glutamatergic synapses. Involved in the formation of the retinal
photoreceptor ribbon synapses (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.2  NT_022517.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the BSN gene promoter:
         NRSF form 1   Olf-1   NRSF form 2   CBF-C   CBF-A   CBF-B   c-Myb   CP1C   CP1A   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBSN promoter sequence
   Search SABiosciences Chromatin IP Primers for BSN

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BSN


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21.31   Ensembl cytogenetic band:  3p21.31   HGNC cytogenetic band: 3p21

BSN Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BSN gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P049591:  view genomic region     (about GC identifiers)

Start:
49,591,922 bp from pter      End:
49,708,982 bp from pter
Size:
117,061 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: BSN_HUMAN, Q9UPA5 (See protein sequence)
Recommended Name: Protein bassoon  
Size: 3926 amino acids; 416469 Da
Subunit: Interacts with ERC2/CAST1, RIMS1 and UNC13A. Part of a complex consisting of ERC2, RIMS1 and BSN (By
similarity)
Subcellular location: Cytoplasm (By similarity). Cell junction, synapse, synaptosome (By similarity). Cytoplasm,
cytoskeleton. Note=Localized to the active zone of presynaptic density (By similarity)
Secondary accessions: O43161 Q7LGH3

Explore the universe of human proteins at neXtProt for BSN: NX_Q9UPA5

Explore proteomics data for BSN at MOPED 

Post-translational modifications:

  • UniProtKB: Myristoylated. The N-terminal myristoylation is not sufficient for presynaptic localization (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9UPA5

  • BSN Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    BSN Protein Expression
    REFSEQ proteins: NP_003449.2  
    ENSEMBL proteins: 
     ENSP00000296452  

    Human Recombinant Protein Products for BSN: 
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    Cloud-Clone Corp. Proteins for BSN 

    Gene Ontology (GO): 5/10 cellular component terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0015630microtubule cytoskeleton IDA--
    GO:0030054cell junction IEA--

    BSN for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR008899 Znf_piccolo
     IPR013083 Znf_RING/FYVE/PHD
     IPR011011 Znf_FYVE_PHD

    Graphical View of Domain Structure for InterPro Entry Q9UPA5

    ProtoNet protein and cluster: Q9UPA5


    BSN for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BSN_HUMAN, Q9UPA5
    Function: Is thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ)
    which regulates neurotransmitter release. Seems to act through binding to ERC2/CAST1. Essential in regulated
    neurotransmitter release from a subset of brain glutamatergic synapses. Involved in the formation of the retinal
    photoreceptor ribbon synapses (By similarity)

         Genatlas biochemistry entry for BSN:
    Bassoon,presynaptic cytomatrix protein,overexpressed in cerebella of patients with multiple system atrophy (MSA)
    potential transcriptional regulator

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0046872metal ion binding IEA--
         
    BSN for ontologies           About GeneDecksing


    Phenotypes:
         6 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Bsn):
     behavior/neurological  hearing/vestibular/ear  mortality/aging  muscle  nervous system 
     vision/eye 

    BSN for phenotypes           About GeneDecksing

    Animal Models:
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    hsa-miR-576-3p hsa-miR-1321 hsa-miR-517a hsa-miR-1224-3p hsa-miR-605 hsa-miR-3074-3p hsa-miR-3653 hsa-miR-342-3p
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    Gene Editing
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for BSN About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Neuroscience
    Neuroscience

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for BSN
        Neuroscience



    BSN for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for BSN

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    5/18 Interacting proteins for BSN (Q9UPA53 ENSP000002964524) via UniProtKB, MINT, STRING, and/or I2D (see all 18)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ERC2O150833, ENSP000002882214I2D: score=2 STRING: ENSP00000288221
    GRIN1Q055863, ENSP000003606164I2D: score=2 STRING: ENSP00000360616
    GRIN2BQ132243, ENSP000002795934I2D: score=1 STRING: ENSP00000279593
    RAB3AP203363, ENSP000002222564I2D: score=1 STRING: ENSP00000222256
    RIMS1Q86UR53, ENSP000002648394I2D: score=1 STRING: ENSP00000264839
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007268synaptic transmission TAS10329005

    BSN for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for BSN

    Search CenterWatch for drugs/clinical trials and news about BSN

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for BSN gene: 
    NM_003458.3  

    Unigene Cluster for BSN:

    Bassoon presynaptic cytomatrix protein
    Hs.194684  [show with all ESTs]
    Unigene Representative Sequence: AF052224
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000296452(uc003cxe.4) ENST00000467456

    miRNA
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    8/164 QIAGEN miScript miRNA Assays for microRNAs that regulate BSN (see all 164):
    hsa-miR-576-3p hsa-miR-1321 hsa-miR-517a hsa-miR-1224-3p hsa-miR-605 hsa-miR-3074-3p hsa-miR-3653 hsa-miR-342-3p
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    Clone
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    Additional mRNA sequence: 

    AB007894.1 AF052224.1 

    5 DOTS entries:

    DT.411943  DT.206144  DT.100037396  DT.91743461  DT.91947864 

    24/99 AceView cDNA sequences (see all 99):

    AF052224 BE700145 AL045982 AA349490 NM_003458 BM914944 Z45025 AB007894 
    BF513520 AA349294 AA442888 BM564812 BM713772 F03960 BX105057 CF453719 
    BM676923 CK023710 T08001 CA412045 BE831521 AA350967 AW298587 AW152535 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    BSN expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACCTTGTGAA
    BSN Expression
    About this image


    See BSN Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for BSN

    SOURCE GeneReport for Unigene cluster: Hs.194684

    UniProtKB/Swiss-Prot: BSN_HUMAN, Q9UPA5
    Tissue specificity: Exclusively expressed in brain

        SABiosciences Expression via Pathway-Focused PCR Array including BSN: 
              Cardiotoxicity in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for BSN gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Bsn1 , 5 bassoon1, 5 86.92(n)1
    89.73(a)1
      9 (59.07 cM)5
    122171  NM_007567.21  NP_031593.21 
     1080960235 
    chicken
    (Gallus gallus)
    Aves BSN1 bassoon (presynaptic cytomatrix protein) 66.85(n)
    64.38(a)
      430723  XM_003641973.1  XP_003642021.1 
    lizard
    (Anolis carolinensis)
    Reptilia BSN6
    bassoon presynaptic cytomatrix protein
    56(a)
    1 ↔ 1
    2(149274869-149553385)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1000040631 protein bassoon-like 52.75(n)
    48.77(a)
      100004063  XM_001920753.3  XP_001920788.3 


    ENSEMBL Gene Tree for BSN (if available)
    TreeFam Gene Tree for BSN (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for BSN gene
    PCLO2  

    BSN for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2122 SNPs in BSN are shown (see all 2122)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1467717771,2
    --49593848(+) TACTTC/TATCTG 1 -- int10--------
    rs1874681621,2
    --49593971(+) CTGAGC/TCTGTG 1 -- int10--------
    rs622612491,2
    C,F--49594060(+) GGAGGT/CGGGAT 1 -- int13Minor allele frequency- C:0.18NA WA 240
    rs1905788141,2
    --49594084(+) TGATAG/TTCATT 1 -- int10--------
    rs1490122871,2
    --49594351(+) CCTCAC/TAGAGG 1 -- int10--------
    rs768958361,2
    C,F--49594360(+) GGTGGG/TTAGAA 1 -- int11Minor allele frequency- T:0.11EA 120
    rs1437984151,2
    C--49594660(+) ATTATA/GTAATC 1 -- int10--------
    rs1827539791,2
    --49594726(+) CCACTC/TTCCAA 1 -- int10--------
    rs1481486581,2
    --49594739(+) TGTGTA/GCCCTG 1 -- int10--------
    rs729360091,2
    C,F--49594740(+) GTGTGC/TCCTGG 1 -- int13Minor allele frequency- T:0.10WA CSA 122

    HapMap Linkage Disequilibrium report for BSN (49591922 - 49708982 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for BSN:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv237379CNV Insertion16902084
    esv1436359CNV Insertion17803354
    nsv508217CNV Loss20534489
    nsv834687CNV Loss17160897
    nsv3812CNV Loss18451855

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 604020    OMIM disorders: --

    10 diseases for BSN:    About MalaCards
    decubitus ulcer    crohn's disease    lambert-eaton myasthenic syndrome    multiple system atrophy
    neuronitis    ulcerative colitis    inflammatory bowel disease    multiple sclerosis
    schizophrenia    retinitis


    BSN for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): BSN
    Human Genome Epidemiology (HuGE) Navigator: BSN (9 documents)

    Export disorders for BSN gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for BSN gene, integrated from 9 sources (see all 32):
    (articles sorted by number of sources associating them with BSN)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and mapping of ZNF231, a novel brain-specific gene encoding neuronal double zinc finger protein whose expression is enhanced in a neurodegenerative disorder, multiple system atrophy. (PubMed id 9806829)1, 2, 3, 9 Hashida H....Sakaki Y. (1998)
    2. The presynaptic cytomatrix protein Bassoon: sequence and chromosomal localization of the human BSN gene. (PubMed id 10329005)1, 2, 3, 9 Winter C....Gundelfinger E.D. (1999)
    3. Association analysis of 3p21 with Crohn's disease in a New Zealand population. (PubMed id 20307617)1, 4 Morgan A.R....Ferguson L.R. (2010)
    4. Association of linear growth impairment in pediatric Crohn's disease and a known height locus: a pilot study. (PubMed id 20846217)1, 4 Lee J.J....Hirschhorn J. (2010)
    5. Effect of BSN-MST1 locus on inflammatory bowel disease and multiple sclerosis susceptibility. (PubMed id 19657358)1, 4 MA!rquez A....Urcelay E. (2009)
    6. Variants at the 3p21 locus influence susceptibility a nd phenotype both in adults and early-onset patients with inflammatory bowel di sease. (PubMed id 20024904)1, 4 Latiano A....Annese V. (2009)
    7. Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population. (PubMed id 19367581)1, 4 So H.C....Sham P.C. (2009)
    8. Genome-wide association study of ulcerative colitis i dentifies three new susceptibility loci, including the HNF4A region. (PubMed id 19915572)1, 4  .... D.P. (2009)
    9. Genetic Risk Profiling And Prediction Of Disease Course In Crohn'S Disease Patients. (PubMed id 19422935)1, 4 Henckaerts L....Vermeire S. (2009)
    10. Genetic utility of broadly defined bipolar schizoaffe ctive disorder as a diagnostic concept. (PubMed id 19567891)1, 4 Hamshere M.L....McGuffin P. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8927 HGNC: 1117 AceView: BSN Ensembl:ENSG00000164061 euGenes: HUgn8927
    ECgene: BSN H-InvDB: BSN

    (According to HUGE)
    About This Section
    HUGE: KIAA0434

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for BSN Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for BSN gene:
    Search GeneIP for patents involving BSN

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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