Aliases for BSG Gene
External Ids for BSG Gene
Previous HGNC Symbols for BSG Gene
Previous GeneCards Identifiers for BSG Gene
The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for BSG Gene
BSG (Basigin (Ok Blood Group)) is a Protein Coding gene. Diseases associated with BSG include Brain Stem Cancer and Brain Stem Glioma. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Degradation of the extracellular matrix. GO annotations related to this gene include mannose binding. An important paralog of this gene is NPTN.
UniProtKB/Swiss-Prot for BSG Gene
Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.