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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

BRWD3 Gene

protein-coding   GIFtS: 49
GCID: GC0XM079926

bromodomain and WD repeat domain containing 3

 Explore 4 diseases affiliated with
BRWD3 via our new
 Human Malady Compendium 
Biological research products
for BRWD3
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Bromodomain And WD Repeat Domain Containing 31 2     Bromo Domain-Containing Protein Disrupted In Leukemia2
MRX931 2 5     Bromodomain And WD Repeat-Containing Protein 32
FLJ385681     Novel WD Repeat Domain Protein2
BRODL2     

External Ids:    HGNC: 173421   Entrez Gene: 2540652   Ensembl: ENSG000001652887   OMIM: 3005535   UniProtKB: Q6RI453   

Export aliases for BRWD3 gene to outside databases

Previous GC identifers: GC0XM079738 GC0XM073504


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for BRWD3:
The protein encoded by this gene contains a bromodomain and several WD repeats. It is thought to have a
chromatin-modifying function, and may thus play a role in transcription. Mutations in this gene cause mental
retardation X-linked type 93, which is also referred to as mental retardation X-linked with macrocephaly. This gene is
also associated with translocations in patients with B-cell chronic lymphocytic leukemia. (provided by RefSeq, May
2010)

UniProtKB/Swiss-Prot: BRWD3_HUMAN, Q6RI45
Function: Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of
cell shape

Gene Wiki entry for BRWD3


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.1  NT_011651.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the BRWD3 gene promoter:
         Elk-1   GATA-3   Egr-1   NF-kappaB   Meis-1b   GATA-1   GATA-2   Meis-1a   NF-kappaB1   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBRWD3 promoter sequence
   Search SABiosciences Chromatin IP Primers for BRWD3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BRWD3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq21.1   Ensembl cytogenetic band:  Xq21.1   HGNC cytogenetic band: Xq21.1

BRWD3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BRWD3 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM079926:  view genomic region     (about GC identifiers)

Start:
79,924,987 bp from pter      End:
80,065,233 bp from pter
Size:
140,247 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: BRWD3_HUMAN, Q6RI45 (See protein sequence)
Recommended Name: Bromodomain and WD repeat-containing protein 3  
Size: 1802 amino acids; 203598 Da
Developmental stage: Expressed in fetal liver
Caution: The translocation involving this gene was originally published as t(X;11)(q13;23) (PubMed:15543602), but BRWD3
is localized to Xq21 and not to Xq13
Sequence caution: Sequence=BAC04641.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: C9IZ39 C9J3F3 Q2T9J6 Q5JRN1 Q6RI37 Q6RI42 Q6RI44 Q8N916
Alternative splicing: 5 isoforms:  Q6RI45-1   Q6RI45-2   Q6RI45-3   Q6RI45-4   Q6RI45-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for BRWD3: NX_Q6RI45

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q6RI45

  • BRWD3 Protein expression data from MOPED and PaxDb:    About this image 
    BRWD3 Protein Expression
    REFSEQ proteins: NP_694984.4  
    ENSEMBL proteins: 
     ENSP00000362372  

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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    BRWD3 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR019775 WD40_repeat_CS
     IPR001680 WD40_repeat
     IPR001487 Bromodomain
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q6RI45

    ProtoNet protein and cluster: Q6RI45

    UniProtKB/Swiss-Prot: BRWD3_HUMAN, Q6RI45
    Similarity: Contains 2 bromo domains
    Similarity: Contains 9 WD repeats


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BRWD3_HUMAN, Q6RI45
    Function: Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of
    cell shape

    Phenotypes:
         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Brwd3):

     craniofacial  embryogenesis  growth/size  limbs/digits/tail 

    BRWD3 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for BRWD3 

    miRNA
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    8/209 QIAGEN miScript miRNA Assays for microRNAs that regulate BRWD3 (see all 209):
    hsa-miR-193a-3p hsa-miR-3938 hsa-miR-376b hsa-miR-199a-3p hsa-miR-128 hsa-miR-3653 hsa-miR-138-2* hsa-miR-519a
    SwitchGear 3'UTR luciferase reporter plasmidBRWD3 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BRWD3

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for BRWD3 (Q6RI453 ENSP000003623724) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBXN7O948883, ENSP000002963284I2D: score=2 STRING: ENSP00000296328
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007010cytoskeleton organization IMP--
    GO:0008360regulation of cell shape IMP--

    BRWD3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for BRWD3
    Search CenterWatch for drugs/clinical trials and news about BRWD3 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for BRWD3 gene: 
    NM_153252.4  

    Unigene Cluster for BRWD3:

    Bromodomain and WD repeat domain containing 3
    Hs.147027  [show with all ESTs]
    Unigene Representative Sequence: NM_153252
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373275(uc010nmi.2 uc004edo.3 uc004edp.3 uc004edq.3 uc010nmj.2 uc004edr.3 uc004eds.3 uc004edt.3 uc004edu.3 uc004edv.3 uc004edw.3 uc004edx.3 uc004edy.3 uc004edz.3 uc004eea.3 uc004eeb.3)
    ENST00000473691 ENST00000497335 ENST00000487313 ENST00000478415

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BRWD3
    8/209 QIAGEN miScript miRNA Assays for microRNAs that regulate BRWD3 (see all 209):
    hsa-miR-193a-3p hsa-miR-3938 hsa-miR-376b hsa-miR-199a-3p hsa-miR-128 hsa-miR-3653 hsa-miR-138-2* hsa-miR-519a
    SwitchGear 3'UTR luciferase reporter plasmidBRWD3 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BRWD3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BRWD3

    Additional cDNA sequence: 

    AK090573.1 AY497046.1 AY497047.1 AY497048.1 AY497049.1 AY497050.1 AY497051.1 AY497052.1 
    AY497053.1 AY497054.1 AY497055.1 AY497056.1 AY497057.1 AY497058.1 AY497059.1 AY497060.1 
    BC039508.2 BC111490.1 

    17 DOTS entries:

    DT.307039  DT.102831267  DT.101960142  DT.100747032  DT.102831265  DT.102831271  DT.40195162  DT.102831263 
    DT.102831266  DT.102831269  DT.102831272  DT.40239666  DT.75179219  DT.100722795  DT.91946409  DT.40200939 
    DT.97770183 

    24/47 AceView cDNA sequences (see all 47):

    AY497053 AY497047 AY497055 AI091909 AI376789 AL699094 AY497048 AY497060 
    AY497051 AY497052 AY497049 BU167659 BC039508 AK095887 AY497058 BM825209 
    AY497054 AY497046 AY497059 AY497057 NM_153252 AY497056 AY497050 AL597077 

    GeneLoc Exon Structure

    5/14 Alternative Splicing Database (ASD) splice patterns (SP) for BRWD3 (see all 14)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^
    SP1:                    -                       -                                                                                                               
    SP2:                    -                       -                       -                       -                                                               
    SP3:                    -                       -     -                                         -                                                               
    SP4:                    -                       -     -                 -                                                                                       
    SP5:                    -           -           -     -                                                                                                         

    ExUns: 26 ^ 27 ^ 28 ^ 29 ^ 30 ^ 31 ^ 32 ^ 33 ^ 34 ^ 35 ^ 36 ^ 37 ^ 38 ^ 39 ^ 40 ^ 41 ^ 42 ^ 43 ^ 44
    SP1:                                                                                                                  
    SP2:                                                                                                                  
    SP3:                                                                                                                  
    SP4:                                                                                                                  
    SP5:                                                                                                                  


    ECgene alternative splicing isoforms for BRWD3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    BRWD3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGAGGAGAAG
    BRWD3 Expression
    About this image
    See BRWD3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for BRWD3

    SOURCE GeneReport for Unigene cluster: Hs.147027

    UniProtKB/Swiss-Prot: BRWD3_HUMAN, Q6RI45
    Tissue specificity: Found in most adult tissues. Down-regulated in a majority of the B-CLL cases examined

        SABiosciences Expression via Pathway-Focused PCR Array including BRWD3: 
              Epigenetic Chromatin Remodeling Factors in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BRWD3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for BRWD3 gene from 8/25 species (see all 25)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Brwd31 , 5 bromodomain and WD repeat domain containing 31, 5 90.99(n)1
    94.83(a)1
      X (47.88 cM)5
    3822361  NM_001081477.11  NP_001074946.11 
     1087370165 
    chicken
    (Gallus gallus)
    Aves BRWD31 bromodomain and WD repeat domain containing 3 80.05(n)
    83.99(a)
      422281  XM_003641079.1  XP_003641127.1 
    lizard
    (Anolis carolinensis)
    Reptilia BRWD36
    --
    80(a)
    1 ↔ 1
    GL343826.1(132754-162913)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia CF150330.12   -- 72.09(n)    CF150330.1 
    zebrafish
    (Danio rerio)
    Actinopterygii si:dkey-237j10.36
    si:dkey-237j10.3
    69(a)
    1 ↔ 1
    5(24757347-24779866)
    fruit fly
    (Drosophila melanogaster)
    Insecta BRWD36
    BRWD3
    28(a)
    possible ortholog
    3R(20144741-20154341)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G474106
    AT5G494306
    WD40/YVTN repeat-like-containing domain
    WD40/YVTN repeat and Bromo-WDR9-I-like domain-cont...
    19(a)
    18(a)
    many ↔ many
    many ↔ many
    2(19448139-19457294)
    5(20037338-20045454)
    rice
    (Oryza sativa)
    Liliopsida --
    WD domain, G-beta repeat domain containing protein...
    17(a)
    1 → many
    3(10865216-10881763)


    ENSEMBL Gene Tree for BRWD3 (if available)
    TreeFam Gene Tree for BRWD3 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for BRWD3 gene
    PHIP2  TAF52  BRWD12  TAF5L2  
    4 SIMAP similar genes for BRWD3 using alignment to 1 protein entry:     BRWD3_HUMAN:
    WDR9    BRWD1    PHIP    WDR83

    BRWD3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1456 NCBI SNPs in BRWD3 are shown (see all 1456    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1923591291,2
    --79924487(+) TCTAGA/TCTTTT 1 -- ds50010--------
    rs66166961,2
    F,H--79924511(+) CATTTC/ATTATC 1 -- ds50014Minor allele frequency- A:0.01NS EA 400
    rs1877158031,2
    --79924810(+) CTAACC/TACATT 1 -- ds50010--------
    rs1926939591,2
    --79924896(+) GCATAA/TTTTTT 1 -- ds50010--------
    rs1849665311,2
    --79924973(+) TAAACA/GTACGG 1 -- ds50010--------
    rs1884989751,2
    --79925206(+) ATTAAC/TATGTT 1 -- ut310--------
    rs20635791,2
    C,F,A,H--79925246(+) ATGACG/AAAAAT 1 -- ut3121Minor allele frequency- A:0.48NA EA NS CSA 2575
    rs1922018251,2
    --79925468(+) TATCAA/TTTTGT 1 -- ut310--------
    rs1844108111,2
    --79925562(+) AGATAA/TGAACT 1 -- ut310--------
    rs112665861,2
    C,F,A,H--79925777(+) TAAGCG/CTATAG 1 -- ut315Minor allele frequency- C:0.25NS EA NA 426

    HapMap Linkage Disequilibrium report for BRWD3 (79924987 - 80065233 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for BRWD3
         1 CNV: 7799
         1 Indel: 62978
    Human Gene Mutation Database (HGMD): BRWD3

    Locus Specific Mutation Databases (LSDB): BRWD3

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    BRWD3 for disorders           About GeneDecksing

    OMIM gene information: 300553   
    OMIM disorders: 300659  
    UniProtKB/Swiss-Prot: BRWD3_HUMAN, Q6RI45
  • Note=A chromosomal aberration involving BRWD3 can be found in patients with B-cell chronic lymphocytic
  • leukemia (B-CLL). Translocation t(X;11)(q21;q23) with ARHGAP20 does not result in fusion transcripts but disrupts both
    genes
  • Defects in BRWD3 are the cause of mental retardation X-linked type 93 (MRX93) [MIM:300659]; also known as
  • mental retardation X-linked with macrocephaly. Mental retardation is characterized by significantly sub-average
    general intellectual functioning associated with impairments in adaptative behavior and manifested during the
    developmental period. Mentally retarded individuals are at least twice as likely to have macrocephaly than are their
    intellectually normal peers

    4 diseases for BRWD3:    About MalaCards
    mental retardation, x-linked    chronic lymphocytic leukemia    lymphocytic leukemia    leukemia


    Export disorders for BRWD3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for BRWD3 gene, integrated from 9 sources (see all 26):
    (articles sorted by number of sources associating them with BRWD3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Translocation t(X;11)(q13;q23) in B-cell chronic lymphocytic leukemia disrupts two novel genes. (PubMed id 15543602)1, 2, 3 Kalla C.... Lichter P. (2005)
    2. Identification of JAK/STAT signalling components by genome-wide RNA interference. (PubMed id 16094372)1, 3, 9 Muller P....Boutros M. (2005)
    3. Mutations in the BRWD3 gene cause X-linked mental retardation associated with macrocephaly. (PubMed id 17668385)1, 2 Field M....Raymond F.L. (2007)
    4. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. Comparative profiling of plasma proteome from breast c ancer patients reveals thrombospondin-1 and BRWD3 as serological biomarkers. (PubMed id 22024541)1 Suh E.J....Lee C. (2012)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. Identification and characterization of a set of conserved and new regulators of cytoskeletal organisation, cell morphology and migration. (PubMed id 21834987)2 Bai S.W.... Ridley A.J. (2011)
    10. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 254065 HGNC: 17342 AceView: BRODL Ensembl:ENSG00000165288 euGenes: HUgn254065
    ECgene: BRWD3 H-InvDB: BRWD3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for BRWD3 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for BRWD3 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for BRWD3 gene:
    Search GeneIP for patents involving BRWD3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013 , 14 May 2013

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