BRWD3 Gene
protein-coding GIFtS: 49
GCID: GC0XM079926
|
|
bromodomain and WD repeat domain containing 3
| |
Aliases for BRWD3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Bromodomain And WD Repeat Domain Containing 31 2 | | Bromo Domain-Containing Protein Disrupted In Leukemia2 | | MRX931 2 5 | | Bromodomain And WD Repeat-Containing Protein 32 | | FLJ385681 | | Novel WD Repeat Domain Protein2 | | BRODL2 | | |
Export aliases for BRWD3 gene to outside databasesPrevious GC identifers: GC0XM079738 GC0XM073504 |
Summaries for BRWD3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for BRWD3: The protein encoded by this gene contains a bromodomain and several WD repeats. It is thought to have achromatin-modifying function, and may thus play a role in transcription. Mutations in this gene cause mentalretardation X-linked type 93, which is also referred to as mental retardation X-linked with macrocephaly. This gene isalso associated with translocations in patients with B-cell chronic lymphocytic leukemia. (provided by RefSeq, May2010) UniProtKB/Swiss-Prot: BRWD3_HUMAN, Q6RI45Function: Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control ofcell shape Gene Wiki entry for BRWD3
|
Genomic Views for BRWD3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_011651.17
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the BRWD3 gene promoter: Elk-1 GATA-3 Egr-1 NF-kappaB Meis-1b GATA-1 GATA-2 Meis-1a NF-kappaB1 Meis-1 Other transcription factors
Search SABiosciences Chromatin IP Primers for BRWD3
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BRWD3 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq21.1 Ensembl cytogenetic band: Xq21.1 HGNC cytogenetic band: Xq21.1BRWD3 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM079926: view genomic region
(about GC identifiers)
Start:
|
79,924,987 bp from pter |
End:
|
80,065,233 bp from pter |
Size:
|
140,247 bases |
Orientation:
|
minus strand |
|
Proteins for BRWD3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: BRWD3_HUMAN, Q6RI45 (See
protein sequence)Recommended Name: Bromodomain and WD repeat-containing protein 3 Size: 1802 amino acids; 203598 Da
Developmental stage: Expressed in fetal liver
Caution: The translocation involving this gene was originally published as t(X;11)(q13;23) (PubMed:15543602), but BRWD3is localized to Xq21 and not to Xq13
Sequence caution: Sequence=BAC04641.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: C9IZ39 C9J3F3 Q2T9J6 Q5JRN1 Q6RI37 Q6RI42 Q6RI44 Q8N916Alternative splicing: 5 isoforms: Q6RI45-1 Q6RI45-2 Q6RI45-3 Q6RI45-4 Q6RI45-5 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for BRWD3: NX_Q6RI45
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6RI45 BRWD3 Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins: NP_694984.4 ENSEMBL proteins: ENSP00000362372 Human Recombinant Protein Products for BRWD3:
BRWD3 Antibody Products: Assay Products for BRWD3: |
Protein
Domains / Families for BRWD3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
BRWD3 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q6RI45ProtoNet protein and cluster: Q6RI45 UniProtKB/Swiss-Prot: BRWD3_HUMAN, Q6RI45Similarity: Contains 2 bromo domainsSimilarity: Contains 9 WD repeats |
Function for BRWD3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: BRWD3_HUMAN, Q6RI45Function: Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control ofcell shapePhenotypes: 4 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Brwd3):
BRWD3 for phenotypes About GeneDecksing
Animal Models:
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BRWD3 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BRWD3 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: BRWD3 (NM_153252) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BRWD3 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat BRWD3  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BRWD3 |
|
Pathways & Interactions for BRWD3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BRWD3
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
 1 Interacting protein for BRWD3 (Q6RI453 ENSP000003623724) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007010 | cytoskeleton organization |
IMP | -- | | GO:0008360 | regulation of cell shape |
IMP | -- |
BRWD3 for ontologies About GeneDecksing
|
Drugs & Compounds for BRWD3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for BRWD3 Search CenterWatch for drugs/clinical trials and news about BRWD3 
|
Transcripts for BRWD3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for BRWD3 gene: NM_153252.4 Unigene Cluster for BRWD3: Bromodomain and WD repeat domain containing 3 Hs.147027 [show with all ESTs]Unigene Representative Sequence: NM_1532525 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000373275(uc010nmi.2 uc004edo.3 uc004edp.3 uc004edq.3 uc010nmj.2 uc004edr.3 uc004eds.3 uc004edt.3 uc004edu.3 uc004edv.3 uc004edw.3 uc004edx.3 uc004edy.3 uc004edz.3 uc004eea.3 uc004eeb.3) ENST00000473691 ENST00000497335 ENST00000487313 ENST00000478415
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BRWD3 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BRWD3 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: BRWD3 (NM_153252) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BRWD3 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat BRWD3  |
Additional cDNA sequence: AK090573.1 AY497046.1 AY497047.1 AY497048.1 AY497049.1 AY497050.1 AY497051.1 AY497052.1 AY497053.1 AY497054.1 AY497055.1 AY497056.1 AY497057.1 AY497058.1 AY497059.1 AY497060.1 BC039508.2 BC111490.1 17 DOTS entries: DT.307039 DT.102831267 DT.101960142 DT.100747032 DT.102831265 DT.102831271 DT.40195162 DT.102831263 DT.102831266 DT.102831269 DT.102831272 DT.40239666 DT.75179219 DT.100722795 DT.91946409 DT.40200939 DT.97770183 24/47 AceView cDNA sequences (see all 47): AY497053 AY497047 AY497055 AI091909 AI376789 AL699094 AY497048 AY497060 AY497051 AY497052 AY497049 BU167659 BC039508 AK095887 AY497058 BM825209 AY497054 AY497046 AY497059 AY497057 NM_153252 AY497056 AY497050 AL597077 GeneLoc Exon Structure
5/14 Alternative Splicing Database (ASD) splice patterns (SP) for BRWD3 (see all 14) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25 | ^ | |
| SP1: | |   | |   | |   | - |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | - |   | |   | |   | |   | - |   | |   | |   | |   | - |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | - |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | - |   | |   | |   | |   | - |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | - |   | |   | - |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 26 | ^ | 27 | ^ | 28 | ^ | 29 | ^ | 30 | ^ | 31 | ^ | 32 | ^ | 33 | ^ | 34 | ^ | 35 | ^ | 36 | ^ | 37 | ^ | 38 | ^ | 39 | ^ | 40 | ^ | 41 | ^ | 42 | ^ | 43 | ^ | 44 | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for BRWD3
|
Expression for BRWD3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| BRWD3 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: GGAGGAGAAG
 About this image See BRWD3 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for BRWD3
SOURCE GeneReport for Unigene cluster: Hs.147027
UniProtKB/Swiss-Prot: BRWD3_HUMAN, Q6RI45Tissue specificity: Found in most adult tissues. Down-regulated in a majority of the B-CLL cases examined SABiosciences Expression via Pathway-Focused PCR Array including BRWD3: | Epigenetic Chromatin Remodeling Factors in human mouse rat |
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BRWD3 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat BRWD3 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BRWD3 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BRWD3 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BRWD3 |
Orthologs for BRWD3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for BRWD3 gene from 8/25 species (see all 25) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Brwd31 , 5 |
bromodomain and WD repeat domain containing 31, 5 |
90.99(n)1 94.83(a)1 |
  |
X (47.88 cM)5 3822361 NM_001081477.11 NP_001074946.11 1087370165 |
chicken (Gallus gallus) |
Aves |
BRWD31 |
bromodomain and WD repeat domain containing 3 |
80.05(n) 83.99(a) |
  |
422281 XM_003641079.1 XP_003641127.1 |
lizard (Anolis carolinensis) |
Reptilia |
BRWD36 |
-- |
80(a) |
1 ↔ 1 |
GL343826.1(132754-162913) |
tropical clawed frog (Xenopus tropicalis) |
Amphibia |
CF150330.12 |
-- |
72.09(n) |
  |
CF150330.1 |
zebrafish (Danio rerio) |
Actinopterygii |
si:dkey-237j10.36 |
si:dkey-237j10.3 |
69(a) |
1 ↔ 1 |
5(24757347-24779866) |
fruit fly (Drosophila melanogaster) |
Insecta |
BRWD36 |
BRWD3 |
28(a) |
possible ortholog |
3R(20144741-20154341) |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
AT2G474106AT5G494306 |
WD40/YVTN repeat-like-containing domainWD40/YVTN repeat and Bromo-WDR9-I-like domain-cont... |
19(a)18(a) |
many ↔ manymany ↔ many |
2(19448139-19457294) 5(20037338-20045454) |
rice (Oryza sativa) |
Liliopsida |
-- |
WD domain, G-beta repeat domain containing protein... |
17(a) |
1 → many |
3(10865216-10881763) |
ENSEMBL Gene Tree for BRWD3 (if available) TreeFam Gene Tree for BRWD3 (if available)  |
Paralogs for BRWD3 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for BRWD3 gene
- PHIP2 TAF52 BRWD12 TAF5L2
4 SIMAP similar genes for BRWD3 using alignment to 1 protein entry: BRWD3_HUMAN:WDR9 BRWD1 PHIP WDR83
BRWD3 for paralogs About GeneDecksing
|
Genomic Variants for BRWD3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr X pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for BRWD3 (79924987 - 80065233 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 2 variations for BRWD3 1 CNV: 7799 1 Indel: 62978 Human Gene Mutation Database (HGMD): BRWD3
Locus Specific Mutation Databases (LSDB): BRWD3
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BRWD3 |
|
Disorders
/ Diseases for BRWD3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
BRWD3 for disorders About GeneDecksing
OMIM gene information: 300553 OMIM disorders: 300659 UniProtKB/Swiss-Prot: BRWD3_HUMAN, Q6RI45
Note=A chromosomal aberration involving BRWD3 can be found in patients with B-cell chronic lymphocyticleukemia (B-CLL). Translocation t(X;11)(q21;q23) with ARHGAP20 does not result in fusion transcripts but disrupts bothgenes Defects in BRWD3 are the cause of mental retardation X-linked type 93 (MRX93) [MIM:300659]; also known asmental retardation X-linked with macrocephaly. Mental retardation is characterized by significantly sub-averagegeneral intellectual functioning associated with impairments in adaptative behavior and manifested during thedevelopmental period. Mentally retarded individuals are at least twice as likely to have macrocephaly than are theirintellectually normal peers 4 diseases for BRWD3: About MalaCardsmental retardation, x-linked chronic lymphocytic leukemia lymphocytic leukemia leukemia Export disorders for BRWD3 gene to outside databases
|
Publications for BRWD3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for BRWD3 gene, integrated from 9 sources (see all 26): (articles sorted by number of sources associating them with BRWD3) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Translocation t(X;11)(q13;q23) in B-cell chronic lymphocytic leukemia disrupts two novel genes. (PubMed id 15543602)1, 2, 3 Kalla C.... Lichter P. (2005)
- Identification of JAK/STAT signalling components by genome-wide RNA interference. (PubMed id 16094372)1, 3, 9 Muller P....Boutros M. (2005)
- Mutations in the BRWD3 gene cause X-linked mental retardation associated with macrocephaly. (PubMed id 17668385)1, 2 Field M....Raymond F.L. (2007)
- The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Comparative profiling of plasma proteome from breast c ancer patients reveals thrombospondin-1 and BRWD3 as serological biomarkers. (PubMed id 22024541)1 Suh E.J....Lee C. (2012)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Identification and characterization of a set of conserved and new regulators of cytoskeletal organisation, cell morphology and migration. (PubMed id 21834987)2 Bai S.W.... Ridley A.J. (2011)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
|
External Searches for BRWD3 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing BRWD3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing BRWD3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing BRWD3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
|
About This Section
| Patent Information for BRWD3 gene: Search GeneIP for patents involving BRWD3
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products for BRWD3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
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| | | | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BRWD3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BRWD3 | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for BRWD3 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BRWD3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BRWD3 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for BRWD3 | | OriGene Custom Protein Services for BRWD3 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat BRWD3 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BRWD3 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BRWD3 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BRWD3 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BRWD3 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BRWD3 |
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| | | Search Tocris compounds for BRWD3 |
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 | | BRWD3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BRWD3 |
|  |  |  |  | | | Search ThermoFisher Antibodies for BRWD3 |
| | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat BRWD3 |
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