BRWD1-IT2 Gene
RNA gene GIFtS: 29
GCID: GC21M040687
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BRWD1 intronic transcript 2 (non-protein coding)(Previous names: chromosome 21 open reading frame 87, non-protein coding...)
(Previous symbols: C21orf87, NCRNA00257)
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Aliases
for BRWD1-IT2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
Subcategory (RNA class): lncRNA
Quality score for this RNA gene is 3
| Aliases |
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| BRWD1 Intronic Transcript 2 (Non-Protein Coding)1 2 | | C21orf871 2 3 | | NCRNA002571 2 3 | | Chromosome 21 Open Reading Frame 871 | | Non-Protein Coding RNA 2571 | | BRWD1 Intronic Transcript 23 |
| External Ids: | HGNC: 164231 | Entrez Gene: 2573572 | Ensembl: ENSG000002555687 | UniProtKB: P590513 | | ORGUL members: | |
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| NONCODE:n409404 | |
Export aliases for BRWD1-IT2 gene to outside databases
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Summaries
for BRWD1-IT2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for BRWD1-IT2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000021.8 NC_018932.1 NT_011512.11
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for BRWD1-IT2
Other transcription factors
Search SABiosciences Chromatin IP Primers for BRWD1-IT2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BRWD1-IT2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 21q22.2 Ensembl cytogenetic band: 21q22.2 HGNC cytogenetic band: 21q22.2BRWD1-IT2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 21 GeneLoc Exon Structure GeneLoc location for GC21M040687: view genomic region
(about GC identifiers)
Start:
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40,685,861 bp from pter |
End:
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40,686,888 bp from pter |
Size:
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1,028 bases |
Orientation:
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minus strand |
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Proteins
for BRWD1-IT2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
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UniProtKB/Swiss-Prot: BRIT2_HUMAN, P59051 (See
protein sequence)Recommended Name: Putative uncharacterized protein encoded by BRWD1-IT2 Size: 145 amino acids; 16132 Da
Caution: Product of a dubious CDS prediction. Probable non-coding RNA
Secondary accessions: A1L3W1 D3DSH8Explore the universe of human proteins at neXtProt for BRWD1-IT2: NX_P59051
BRWD1-IT2 Protein expression data from MOPED and PaxDb: --
ENSEMBL proteins: ENSP00000443539
Human Recombinant Protein Products:
BRWD1-IT2 Antibody Products:
Assay Products for BRWD1-IT2: |
Protein
Domains /
Families
for BRWD1-IT2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: P59051 |
Function
for BRWD1-IT2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BRWD1-IT2 |
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Pathways & Interactions
for BRWD1-IT2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BRWD1-IT2
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Drugs & Compounds
for BRWD1-IT2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for BRWD1-IT2
Search CenterWatch for drugs/clinical trials and news about BRWD1-IT2 
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Transcripts
for BRWD1-IT2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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REFSEQ mRNAs for BRWD1-IT2 gene (2 alternative transcripts): NM_001040140.1 NM_153455.1 Unigene Cluster for BRWD1-IT2: BRWD1 intronic transcript 2 (non-protein coding) Hs.729612 [show with all ESTs]Unigene Representative Sequence: BM5531641 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000539811(uc021wjg.1)
Additional cDNA sequence: AF426265.1 BC130301.1 BC130303.1 NR_033800.1 1 DOTS entry: DT.305975
GeneLoc Exon Structure
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Expression
for BRWD1-IT2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| Expression evidence for BRWD1-IT2:none
BRWD1-IT2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTTGGATGGA
About this image
Genevestigator expression for BRWD1-IT2
SOURCE GeneReport for Unigene cluster: Hs.729612
SABiosciences Custom PCR Arrays for BRWD1-IT2
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BRWD1-IT2
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat BRWD1-IT2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BRWD1-IT2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BRWD1-IT2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BRWD1-IT2 |
Orthologs
for BRWD1-IT2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for BRWD1-IT2 (if available)
TreeFam Gene Tree for BRWD1-IT2 (if available) |
Paralogs
for BRWD1-IT2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for BRWD1-IT2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 21 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for BRWD1-IT2 (40685861 - 40686888 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for BRWD1-IT2: -- | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for BRWD1-IT2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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Publications
for BRWD1-IT2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for BRWD1-IT2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with BRWD1-IT2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Nineteen additional unpredicted transcripts from human chromosome 21. (PubMed id 12036297)1, 2, 3 Reymond A....Antonarakis S.E. (2002)
- Functional analysis and identification of cis-regulat ory elements of human chromosome 21 gene promoters. (PubMed id 20494980)1 Warnatz H.J....Yaspo M.L. (2010)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- The DNA sequence of human chromosome 21. (PubMed id 10830953)2 Hattori M....Yaspo M.L. (2000)
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External Searches for BRWD1-IT2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing BRWD1-IT2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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Other Databases showing BRWD1-IT2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing BRWD1-IT2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for BRWD1-IT2 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for BRWD1-IT2 gene:
Search GeneIP for patents involving BRWD1-IT2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for BRWD1-IT2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat BRWD1-IT2 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BRWD1-IT2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BRWD1-IT2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BRWD1-IT2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BRWD1-IT2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BRWD1-IT2 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BRWD1-IT2 |
|  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BRWD1-IT2 |
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Last full update: 18 Mar 2013 -
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