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Aliases for BRSK2 Gene

Aliases for BRSK2 Gene

  • BR Serine/Threonine Kinase 2 2 3 5
  • Brain-Specific Serine/Threonine-Protein Kinase 2 3 4
  • Serine/Threonine-Protein Kinase SAD-A 3 4
  • BR Serine/Threonine-Protein Kinase 2 3 4
  • Serine/Threonine-Protein Kinase 29 3 4
  • Brain-Selective Kinase 2 3 4
  • EC 2.7.11.1 4 63
  • C11orf7 3 4
  • PEN11B 3 4
  • STK29 3 4
  • SADA 3 4
  • Chromsosome 11 Open Reading Frame 7 2
  • Testicular Tissue Protein Li 30 3
  • Serine/Threonine Kinase 29 2
  • Protein Kinase SAD1B 3
  • EC 2.7.11.26 4
  • EC 2.7.11 63
  • SAD1 3

External Ids for BRSK2 Gene

Previous HGNC Symbols for BRSK2 Gene

  • C11orf7
  • STK29

Previous GeneCards Identifiers for BRSK2 Gene

  • GC11P001368
  • GC11P001247

Summaries for BRSK2 Gene

GeneCards Summary for BRSK2 Gene

BRSK2 (BR Serine/Threonine Kinase 2) is a Protein Coding gene. Diseases associated with BRSK2 include Limbic Encephalitis and Pleural Tuberculosis. Among its related pathways are Glucose / Energy Metabolism and DNA Damage. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is BRSK1.

UniProtKB/Swiss-Prot for BRSK2 Gene

  • Serine/threonine-protein kinase that plays a key role in polarization of neurons and axonogenesis, cell cycle progress and insulin secretion. Phosphorylates CDK16, CDC25C, MAPT/TAU, PAK1 and WEE1. Following phosphorylation and activation by STK11/LKB1, acts as a key regulator of polarization of cortical neurons, probably by mediating phosphorylation of microtubule-associated proteins such as MAPT/TAU at Thr-529 and Ser-579. Also regulates neuron polarization by mediating phosphorylation of WEE1 at Ser-642 in postmitotic neurons, leading to down-regulate WEE1 activity in polarized neurons. Plays a role in the regulation of the mitotic cell cycle progress and the onset of mitosis. Plays a role in the regulation of insulin secretion in response to elevated glucose levels, probably via phosphorylation of CDK16 and PAK1. While BRSK2 phosphorylated at Thr-174 can inhibit insulin secretion (PubMed:22798068), BRSK2 phosphorylated at Thr-260 can promote insulin secretion (PubMed:22669945). Regulates reorganization of the actin cytoskeleton. May play a role in the apoptotic response triggered by endoplasmatic reticulum (ER) stress.

Gene Wiki entry for BRSK2 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BRSK2 Gene

Genomics for BRSK2 Gene

Regulatory Elements for BRSK2 Gene

Enhancers for BRSK2 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around BRSK2 on UCSC Golden Path with GeneCards custom track

Promoters for BRSK2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around BRSK2 on UCSC Golden Path with GeneCards custom track

Genomic Location for BRSK2 Gene

Chromosome:
11
Start:
1,389,899 bp from pter
End:
1,462,689 bp from pter
Size:
72,791 bases
Orientation:
Plus strand

Genomic View for BRSK2 Gene

Genes around BRSK2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BRSK2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BRSK2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BRSK2 Gene

Proteins for BRSK2 Gene

  • Protein details for BRSK2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IWQ3-BRSK2_HUMAN
    Recommended name:
    Serine/threonine-protein kinase BRSK2
    Protein Accession:
    Q8IWQ3
    Secondary Accessions:
    • B3KVE9
    • E9PLM7
    • O60843
    • O95099
    • Q5J5B4
    • Q6ZMQ4
    • Q8TB60

    Protein attributes for BRSK2 Gene

    Size:
    736 amino acids
    Molecular mass:
    81633 Da
    Cofactor:
    Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
    Quaternary structure:
    • Interacts with FZR1, a regulatory subunit of the APC ubiquitin ligase complex. Interacts with COPS5. Interacts with PAK1.
    SequenceCaution:
    • Sequence=AAD09654.1; Type=Erroneous termination; Positions=663; Note=Translated as Gly.; Evidence={ECO:0000305}; Sequence=AAD09654.1; Type=Frameshift; Positions=640; Evidence={ECO:0000305}; Sequence=AAH24291.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for BRSK2 Gene

neXtProt entry for BRSK2 Gene

Proteomics data for BRSK2 Gene at MOPED

Selected DME Specific Peptides for BRSK2 Gene

Post-translational modifications for BRSK2 Gene

  • Phosphorylated at Thr-174 by STK11/LKB1 in complex with STE20-related adapter-alpha (STRADA) pseudo kinase and CAB39. Not phosphorylated at Thr-174 by CaMKK2. In contrast, it is phosphorylated and activated by CaMKK1. May be inactivated via dephosphorylation of Thr-174 by PP2C. Phosphorylated at Thr-260 by PKA. Phosphorylation at Thr-260 by PKA was not observed in another study (PubMed:18339622), but this may reflect differences in the experimental approach. Phosphorylation at Thr-260 seems to play a role in the regulation of insulin secretion (PubMed:22669945).
  • Polyubiquitinated by the APC complex in conjunction with FZR1, leading to its proteasomal degradation. Targeted for proteasomal degradation by interaction with COPS5. BRSK2 levels change during the cell cycle. BRSK2 levels are low at the G1/S boundary and gradually increase as cells progress into G2 phase. BRSK2 levels decrease rapidly at the end of mitosis.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

  • Cell Signaling Technology (CST) Antibodies for BRSK2 (BRSK2)

Domains & Families for BRSK2 Gene

Gene Families for BRSK2 Gene

Graphical View of Domain Structure for InterPro Entry

Q8IWQ3

UniProtKB/Swiss-Prot:

BRSK2_HUMAN :
  • The KEN box motif is required for interaction with FZR1/CDH1 and essential for APC(CDH1)-mediated ubiquitination.
  • Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Domain:
  • The KEN box motif is required for interaction with FZR1/CDH1 and essential for APC(CDH1)-mediated ubiquitination.
  • Contains 1 protein kinase domain.
  • Contains 1 UBA domain.
Family:
  • Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
genes like me logo Genes that share domains with BRSK2: view

Function for BRSK2 Gene

Molecular function for BRSK2 Gene

UniProtKB/Swiss-Prot CatalyticActivity:
ATP + a protein = ADP + a phosphoprotein.
UniProtKB/Swiss-Prot CatalyticActivity:
ATP + [tau protein] = ADP + [tau protein] phosphate.
UniProtKB/Swiss-Prot EnzymeRegulation:
Activated by phosphorylation on Thr-174 by STK11/LKB1.
UniProtKB/Swiss-Prot Function:
Serine/threonine-protein kinase that plays a key role in polarization of neurons and axonogenesis, cell cycle progress and insulin secretion. Phosphorylates CDK16, CDC25C, MAPT/TAU, PAK1 and WEE1. Following phosphorylation and activation by STK11/LKB1, acts as a key regulator of polarization of cortical neurons, probably by mediating phosphorylation of microtubule-associated proteins such as MAPT/TAU at Thr-529 and Ser-579. Also regulates neuron polarization by mediating phosphorylation of WEE1 at Ser-642 in postmitotic neurons, leading to down-regulate WEE1 activity in polarized neurons. Plays a role in the regulation of the mitotic cell cycle progress and the onset of mitosis. Plays a role in the regulation of insulin secretion in response to elevated glucose levels, probably via phosphorylation of CDK16 and PAK1. While BRSK2 phosphorylated at Thr-174 can inhibit insulin secretion (PubMed:22798068), BRSK2 phosphorylated at Thr-260 can promote insulin secretion (PubMed:22669945). Regulates reorganization of the actin cytoskeleton. May play a role in the apoptotic response triggered by endoplasmatic reticulum (ER) stress.

Enzyme Numbers (IUBMB) for BRSK2 Gene

Gene Ontology (GO) - Molecular Function for BRSK2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000287 magnesium ion binding IDA 14976552
genes like me logo Genes that share ontologies with BRSK2: view
genes like me logo Genes that share phenotypes with BRSK2: view

Animal Models for BRSK2 Gene

MGI Knock Outs for BRSK2:

Animal Model Products

  • Taconic Biosciences Mouse Models for BRSK2

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for BRSK2 Gene

Localization for BRSK2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for BRSK2 Gene

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, perinuclear region. Endoplasmic reticulum. Note=Detected at centrosomes during mitosis. Localizes to the endoplasmic reticulum in response to stress caused by tunicamycin.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for BRSK2 Gene COMPARTMENTS Subcellular localization image for BRSK2 gene
Compartment Confidence
cytoskeleton 5
endoplasmic reticulum 5
cytosol 3
nucleus 2
extracellular 1
mitochondrion 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for BRSK2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with BRSK2: view

Pathways & Interactions for BRSK2 Gene

genes like me logo Genes that share pathways with BRSK2: view

Pathways by source for BRSK2 Gene

3 Cell Signaling Technology pathways for BRSK2 Gene
1 BioSystems pathway for BRSK2 Gene
1 Qiagen pathway for BRSK2 Gene

SIGNOR curated interactions for BRSK2 Gene

Activates:
Is activated by:

Gene Ontology (GO) - Biological Process for BRSK2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006468 protein phosphorylation IEA,IDA 14976552
GO:0006887 exocytosis IEA --
GO:0007067 mitotic nuclear division IEA --
GO:0007409 axonogenesis IEA,ISS --
GO:0030010 establishment of cell polarity IEA,ISS --
genes like me logo Genes that share ontologies with BRSK2: view

Drugs & Compounds for BRSK2 Gene

(2) Drugs for BRSK2 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Adenosine triphosphate Approved Nutra 0
Magnesium Nutra 0

(1) Additional Compounds for BRSK2 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
ADP
  • Adenosindiphosphorsaeure
  • Adenosine 5'-pyrophosphate
  • Adenosine diphosphate
  • Adenosine pyrophosphate
  • Adenosine-5'-diphosphate
Full agonist, Agonist 58-64-0
genes like me logo Genes that share compounds with BRSK2: view

Transcripts for BRSK2 Gene

Unigene Clusters for BRSK2 Gene

BR serine/threonine kinase 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for BRSK2 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b · 13c ^ 14 ^ 15 ^ 16a · 16b ^ 17 ^ 18 ^ 19a · 19b · 19c · 19d
SP1: - - -
SP2:
SP3:
SP4: - - -
SP5: - - -
SP6: -
SP7: - -
SP8:
SP9: -

Relevant External Links for BRSK2 Gene

GeneLoc Exon Structure for
BRSK2
ECgene alternative splicing isoforms for
BRSK2

Expression for BRSK2 Gene

mRNA expression in normal human tissues for BRSK2 Gene

mRNA differential expression in normal tissues according to GTEx for BRSK2 Gene

This gene is overexpressed in Brain - Cerebellum (x6.2), Brain - Cerebellar Hemisphere (x5.7), Brain - Cortex (x4.9), and Pancreas (x4.9).

Protein differential expression in normal tissues from HIPED for BRSK2 Gene

This gene is overexpressed in Lung (27.9), Frontal cortex (16.7), Fetal Brain (10.2), and Plasma (6.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for BRSK2 Gene



SOURCE GeneReport for Unigene cluster for BRSK2 Gene Hs.170819

mRNA Expression by UniProt/SwissProt for BRSK2 Gene

Q8IWQ3-BRSK2_HUMAN
Tissue specificity: Detected in pancreas islets (at protein level).
genes like me logo Genes that share expression patterns with BRSK2: view

Protein tissue co-expression partners for BRSK2 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for BRSK2 Gene

Orthologs for BRSK2 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for BRSK2 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia BRSK2 35
  • 92.02 (n)
  • 97.45 (a)
BRSK2 36
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia BRSK2 35
  • 91.6 (n)
  • 98.84 (a)
BRSK2 36
  • 92 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Brsk2 35
  • 89.18 (n)
  • 98.33 (a)
Brsk2 16
Brsk2 36
  • 95 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Brsk2 35
  • 88.83 (n)
  • 97.7 (a)
oppossum
(Monodelphis domestica)
Mammalia BRSK2 36
  • 82 (a)
OneToOne
chicken
(Gallus gallus)
Aves BRSK2 35
  • 79.97 (n)
  • 93.17 (a)
BRSK2 36
  • 80 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia BRSK2 36
  • 92 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia brsk2 35
  • 75.21 (n)
  • 86.06 (a)
zebrafish
(Danio rerio)
Actinopterygii Dr.28076 35
LOC100334759 35
  • 77.1 (n)
  • 91.61 (a)
BRSK2 (1 of 2) 36
  • 82 (a)
OneToMany
BRSK2 (2 of 2) 36
  • 83 (a)
OneToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP012244 35
  • 56.24 (n)
  • 52.12 (a)
fruit fly
(Drosophila melanogaster)
Insecta sff 35
  • 60.66 (n)
  • 62.76 (a)
sff 36
  • 48 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea sad-1 35
  • 57.02 (n)
  • 64.64 (a)
sad-1 36
  • 43 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes GIN4 36
  • 19 (a)
ManyToMany
HSL1 36
  • 16 (a)
ManyToMany
KCC4 36
  • 21 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 52 (a)
OneToMany
Species with no ortholog for BRSK2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for BRSK2 Gene

ENSEMBL:
Gene Tree for BRSK2 (if available)
TreeFam:
Gene Tree for BRSK2 (if available)

Paralogs for BRSK2 Gene

Paralogs for BRSK2 Gene

genes like me logo Genes that share paralogs with BRSK2: view

Variants for BRSK2 Gene

Sequence variations from dbSNP and Humsavar for BRSK2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1105398 -- 1,399,294(-) ACCAT(C/T)CTATC intron-variant
rs1105470 -- 1,404,415(+) CCAGG(A/G)CAGAC intron-variant
rs1110029 -- 1,404,146(-) GCTGG(A/G)GGTGC intron-variant
rs1316316 -- 1,461,857(-) ACCGT(C/T)TTTAG nc-transcript-variant, utr-variant-3-prime
rs1317780 -- 1,423,098(+) CCAGG(C/G)CCCAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for BRSK2 Gene

Variant ID Type Subtype PubMed ID
esv2743878 CNV Deletion 23290073
esv2669189 CNV Deletion 23128226
dgv963n71 CNV Loss 21882294
dgv968n71 CNV Loss 21882294
dgv969n71 CNV Loss 21882294
dgv971n71 CNV Loss 21882294
dgv973n71 CNV Loss 21882294
nsv896691 CNV Loss 21882294
nsv896692 CNV Loss 21882294
dgv10n68 CNV Loss 17160897
nsv469925 CNV Loss 18288195
nsv467642 CNV Loss 19166990
dgv974n71 CNV Loss 21882294
esv2743912 CNV Deletion 23290073
esv2743913 CNV Deletion 23290073
esv2743914 CNV Deletion 23290073
dgv975n71 CNV Loss 21882294
esv2743915 CNV Deletion 23290073
nsv38732 CNV Insertion 16902084
esv1644887 CNV Insertion 17803354
nsv825696 CNV Gain 20364138
esv2743916 CNV Deletion 23290073
nsv39243 CNV Loss 16902084
dgv147e201 CNV Deletion 23290073
esv2743918 CNV Deletion 23290073
dgv148e201 CNV Deletion 23290073
dgv149e201 CNV Deletion 23290073
esv23631 CNV Gain 19812545
esv2657570 CNV Deletion 23128226
esv988117 CNV Deletion 20482838
esv1076319 CNV Deletion 17803354
esv2743926 CNV Deletion 23290073
esv1962941 CNV Deletion 18987734
esv2743927 CNV Deletion 23290073
esv24637 CNV Loss 19812545
dgv976n71 CNV Loss 21882294
nsv7639 CNV Loss 18451855
esv2743928 CNV Deletion 23290073
esv2743929 CNV Deletion 23290073
nsv820797 CNV Deletion 20802225
esv23309 CNV Gain+Loss 19812545
nsv512202 CNV Loss 21212237
nsv514599 CNV Complex 21397061
esv2743930 CNV Deletion 23290073
esv2743932 CNV Deletion 23290073
esv1010049 CNV Gain 20482838
esv1341351 CNV Deletion 17803354
nsv896707 CNV Loss 21882294
esv2743933 CNV Deletion 23290073
esv2743934 CNV Deletion 23290073
esv2743935 CNV Deletion 23290073
esv2743936 CNV Deletion 23290073
esv2677742 CNV Deletion 23128226
esv2743937 CNV Deletion 23290073
esv1733198 CNV Deletion 17803354

Variation tolerance for BRSK2 Gene

Residual Variation Intolerance Score: 3.54% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.65; 31.55% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for BRSK2 Gene

Human Gene Mutation Database (HGMD)
BRSK2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BRSK2 Gene

Disorders for BRSK2 Gene

MalaCards: The human disease database

(2) MalaCards diseases for BRSK2 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
limbic encephalitis
pleural tuberculosis
  • pearly disease
- elite association - COSMIC cancer census association via MalaCards
Search BRSK2 in MalaCards View complete list of genes associated with diseases

Relevant External Links for BRSK2

Genetic Association Database (GAD)
BRSK2
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
BRSK2
genes like me logo Genes that share disorders with BRSK2: view

No data available for UniProtKB/Swiss-Prot and Genatlas for BRSK2 Gene

Publications for BRSK2 Gene

  1. Repeat-directed isolation of a novel gene preferentially expressed from the maternal allele in human placenta. (PMID: 9929968) Miura K. … Ishimaru T. (J. Hum. Genet. 1999) 2 3 4 67
  2. BR serine/threonine kinase 2: a new autoantigen in paraneoplastic limbic encephalitis. (PMID: 16165222) Sabater L. … Graus F. (J. Neuroimmunol. 2005) 3 23
  3. A HhaI/BstUI polymorphism in a novel gene at human chromosome 11p15.5. (PMID: 9852686) Miura K. … Jinno Y. (J. Hum. Genet. 1998) 2 3
  4. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  5. BRSK2 is a valosin-containing protein (VCP)-interacting protein that affects VCP functioning in endoplasmic reticulum-associated degradation. (PMID: 23907667) Wang Y. … Yu L. (Biotechnol. Lett. 2013) 3

Products for BRSK2 Gene

Sources for BRSK2 Gene

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