BRSK1 Gene
protein-coding GIFtS: 57
GCID: GC19P055795
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|
BR serine/threonine kinase 1
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Aliases
for BRSK1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| BR Serine/Threonine Kinase 11 2 | | EC 2.7.11.13 8 | | KIAA18111 3 5 | | Protein Kinase SAD1A2 | | Brain-Selective Kinase 12 3 | | SAD1 Kinase2 | | Brain-Specific Serine/Threonine-Protein Kinase 12 3 | | SadB Kinase Short Isoform2 | | Serine/Threonine-Protein Kinase SAD-B2 3 | | Serine/Threonine-Protein Kinase BRSK12 | | Synapses Of Amphids Defective Homolog 12 3 | | EC 2.7.11.263 | | BR Serine/Threonine-Protein Kinase 12 3 | | SAD13 | | HSAD11 | | SADB3 | | SAD1 Homolog2 3 | | EC 2.7.118 |
Export aliases for BRSK1 gene to outside databasesPrevious GC identifers: GC19P060383 GC19P060488 GC19P052118 |
Summaries
for BRSK1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: BRSK1_HUMAN, Q8TDC3Function: Serine/threonine-protein kinase that plays a key role in polarization of neurons and centrosome duplication.Phosphorylates CDC25B, CDC25C, MAPT/TAU, RIMS1, TUBG1, TUBG2 and WEE1. Following phosphorylation and activation bySTK11/LKB1, acts as a key regulator of polarization of cortical neurons, probably by mediating phosphorylation ofmicrotubule-associated proteins such as MAPT/TAU at 'Thr-529' and 'Ser-579'. Also regulates neuron polarization bymediating phosphorylation of WEE1 at 'Ser-642' in post-mitotic neurons, leading to down-regulate WEE1 activity inpolarized neurons. In neurons, localizes to synaptic vesicles and plays a role in neurotransmitter release, possiblyby phosphorylating RIMS1. Also acts as a positive regulator of centrosome duplication by mediating phosphorylation ofgamma-tubulin (TUBG1 and TUBG2) at 'Ser-131', leading to translocation of gamma-tubulin and its associated proteins tothe centrosome. Involved in the UV-induced DNA damage checkpoint response, probably by inhibiting CDK1 activitythrough phosphorylation and activation of WEE1, and inhibition of CDC25B and CDC25C
Gene Wiki entry for BRSK1
|
Genomic Views
for BRSK1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the BRSK1 gene promoter:
Spz1 p300 MyoD LUN-1 Arnt Roaz C/EBPalpha PPAR-gamma1 Cart-1 PPAR-gamma2
Other transcription factors
Search SABiosciences Chromatin IP Primers for BRSK1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BRSK1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.4 Ensembl cytogenetic band: 19q13.42 HGNC cytogenetic band: 19q13.4BRSK1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P055795: view genomic region
(about GC identifiers)
Start:
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55,793,440 bp from pter |
End:
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55,823,930 bp from pter |
Size:
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30,491 bases |
Orientation:
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plus strand |
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Proteins
for BRSK1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: BRSK1_HUMAN, Q8TDC3 (See
protein sequence)Recommended Name: Serine/threonine-protein kinase BRSK1 Size: 778 amino acids; 85087 Da
Cofactor: Magnesium (By similarity)
Subcellular location: Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, centrosome (By similarity). Cell junction, synapse(By similarity). Note=Localizes to synaptic vesicles in neurons (By similarity). Nuclear in the absence of DNA damage.Translocated to the nucleus in response to UV- or MMS-induced DNA damage
Sequence caution: Sequence=AAH16681.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: F1DG44 Q5J5B5 Q8NDD0 Q8NDR4 Q8TDC2 Q96AV4 Q96JL4Alternative splicing: 3 isoforms: Q8TDC3-1 Q8TDC3-2 Q8TDC3-3 Explore the universe of human proteins at neXtProt for BRSK1: NX_Q8TDC3
Post-translational modifications:
Phosphorylated at Thr-189 by STK11/LKB1 in complex with STE20-related adapter-alpha (STRADA) pseudo kinase and CAB39.Not phosphorylated at Thr-189 by CaMKK2. In contrast, it is phosphorylated and activated by CaMKK1. May be inactivatedvia dephosphorylation of Thr-189 by PP2C1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8TDC3
4/9 DME Specific Peptides for BRSK1 (Q8TDC3) (see all 9)
BRSK1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_115806.1
ENSEMBL proteins: ENSP00000468190 ENSP00000310649 ENSP00000467357 ENSP00000466755 ENSP00000466380 ENSP00000320853
Human Recombinant Protein Products:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
BRSK1 for ontologies About GeneDecksing
BRSK1 Antibody Products:
Assay Products for BRSK1: |
Protein
Domains /
Families
for BRSK1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
BRSK1 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q8TDC3ProtoNet protein and cluster: Q8TDC3 UniProtKB/Swiss-Prot: BRSK1_HUMAN, Q8TDC3Similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamilySimilarity: Contains 1 protein kinase domainSimilarity: Contains 1 UBA domain |
Function
for BRSK1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: BRSK1_HUMAN, Q8TDC3Function: Serine/threonine-protein kinase that plays a key role in polarization of neurons and centrosome duplication.Phosphorylates CDC25B, CDC25C, MAPT/TAU, RIMS1, TUBG1, TUBG2 and WEE1. Following phosphorylation and activation bySTK11/LKB1, acts as a key regulator of polarization of cortical neurons, probably by mediating phosphorylation ofmicrotubule-associated proteins such as MAPT/TAU at 'Thr-529' and 'Ser-579'. Also regulates neuron polarization bymediating phosphorylation of WEE1 at 'Ser-642' in post-mitotic neurons, leading to down-regulate WEE1 activity inpolarized neurons. In neurons, localizes to synaptic vesicles and plays a role in neurotransmitter release, possiblyby phosphorylating RIMS1. Also acts as a positive regulator of centrosome duplication by mediating phosphorylation ofgamma-tubulin (TUBG1 and TUBG2) at 'Ser-131', leading to translocation of gamma-tubulin and its associated proteins tothe centrosome. Involved in the UV-induced DNA damage checkpoint response, probably by inhibiting CDK1 activitythrough phosphorylation and activation of WEE1, and inhibition of CDC25B and CDC25CCatalytic activity: ATP + a protein = ADP + a phosphoproteinCatalytic activity: ATP + [tau protein] = ADP + [tau protein] phosphateEnzyme regulation: Activated by phosphorylation on Thr-189 by STK11/LKB1Enzyme Numbers (IUBMB): EC 2.7.11.11 2 EC 2.7.112 EC 2.7.11.261
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BRSK1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BRSK1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: BRSK1 (NM_032430) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BRSK1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BRSK1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BRSK1 |
Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table
BRSK1 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for BRSK1:
Animal Models:
Mouse knock-out Brsk1tm1Jrs for BRSK1
6 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Brsk1):
BRSK1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for BRSK1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Neuroscience | | | 2 | Cell Cycle / Checkpoint Control | | | 3 | LKB1 signaling events | | | 4 | Glucose / Energy Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 
Cell Signaling Technology (CST) Pathways for BRSK1
1  BioSystems Pathway for BRSK1
BRSK1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BRSK1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/15 Interacting proteins for BRSK1 (Q8TDC32, 3 ENSP000003106494) via UniProtKB, MINT, STRING, and/or I2D (see all 15)About this table
Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11): About this table
BRSK1 for ontologies About GeneDecksing
|
Drugs & Compounds
for BRSK1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for BRSK1
4 HMDB Compounds for BRSK1 About this table
Search CenterWatch for drugs/clinical trials and news about BRSK1
|
Transcripts
for BRSK1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for BRSK1 gene: NM_032430.1 Unigene Cluster for BRSK1: BR serine/threonine kinase 1 Hs.182081 [show with all ESTs]Unigene Representative Sequence: AF4798278 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000590333 ENST00000309383(uc002qkf.3 uc021vbs.1 uc002qkg.3 uc002qkh.3)
ENST00000585418 ENST00000592539 ENST00000591774 ENST00000326848 ENST00000586626
ENST00000588584
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BRSK1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BRSK1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: BRSK1 (NM_032430) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BRSK1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BRSK1 |
Additional cDNA sequence: AB058714.1 AF479826.1 AF479827.1 AK124999.1 AL831945.1 AL834275.1 AY458602.1 AY505124.1 BC016681.1 HQ830199.1 4 DOTS entries: DT.100023087 DT.101965011 DT.92419440 DT.95156946 24/43 AceView cDNA sequences (see all 43): BU742909 CK819107 BM129669 AL834275 CK819625 AF479826 BQ717903 AL831945 AK124999 AB058714 BM129382 NM_032430 AF479827 CN485185 BQ086295 BM675364 BG715357 AL133704 BG819795 BE222941 BC016681 AA326737 BU623793 CA432345
GeneLoc Exon Structure
|
Expression
for BRSK1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| BRSK1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCGGGAGGGG
About this image
See BRSK1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for BRSK1
SOURCE GeneReport for Unigene cluster: Hs.182081
UniProtKB/Swiss-Prot: BRSK1_HUMAN, Q8TDC3Tissue specificity: Widely expressed, with highest levels in brain and testis. Protein levels remain constantthroughout the cell cycle
SABiosciences Custom PCR Arrays for BRSK1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BRSK1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat BRSK1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BRSK1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BRSK1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BRSK1 |
Orthologs
for BRSK1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for BRSK1 gene from 6/24 species (see all 24) About this table
ENSEMBL Gene Tree for BRSK1 (if available)
TreeFam Gene Tree for BRSK1 (if available) |
Paralogs
for BRSK1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for BRSK1 gene
- NUAK12 MARK12 BRSK22 SIK32 SNRK2 SIK22 NUAK22 MARK22
- NIM12 SIK12 MARK42 MARK32
18/23 SIMAP similar genes for BRSK1 using alignment to 4 protein entries: BRSK1_HUMAN (see all proteins)
(see all similar genes):BRSK2 PRKAA1 CAMK1D PNCK AURKB PRKAA2
TSSK3 CAMK1 DAPK2 PRKACG TSSK4 TSSK6
PSKH2 TSSK1 TSSK1B TSSK2 MARK4 PRKX
BRSK1 for paralogs About GeneDecksing
|
Genomic Variants
for BRSK1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for BRSK1 (55793440 - 55823930 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for BRSK1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BRSK1 |
|
Disorders
/ Diseases
for BRSK1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
BRSK1 for disorders About GeneDecksing
OMIM gene information: 609235
OMIM disorders: --
4  diseases for BRSK1: About MalaCardspeutz-jeghers syndrome premature ovarian failure malaria neuronitis
Human Genome Epidemiology (HuGE) Navigator: BRSK1 (2 documents)
Export disorders for BRSK1 gene to outside databases
|
Publications
for BRSK1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for BRSK1 gene, integrated from 9 sources (see all 21):
(articles sorted by number of sources associating them with BRSK1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1. (PubMed id 14976552)1, 2, 3 Lizcano J.M....Alessi D.R. (2004)
- Human SAD1 kinase is involved in UV-induced DNA damage checkpoint function. (PubMed id 15150265)1, 2, 9 Lu R.... Nakanishi M. (2004)
- SADB phosphorylation of gamma-tubulin regulates centr osome duplication. (PubMed id 19648910)1, 2 Alvarado-Kristensson M....Carrera A.C. (2009)
- Investigating the regulation of brain-specific kinases 1 and 2 by phosphorylation. (PubMed id 18339622)1, 2 Bright N.J....Thornton C. (2008)
- SAD: a presynaptic kinase associated with synaptic vesicles and the active zone cytomatrix that regulates neurotransmitter release. (PubMed id 16630837)1, 2 Inoue E....Takai Y. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11347906)1, 2 Nagase T.... Ohara O. (2001)
- Phosphorylation of microtubule-associated protein tau by AMPK-related kinases. (PubMed id 21985311)2 Yoshida H. and Goedert M. (2012)
- Replication of loci influencing ages at menarche and m enopause in Hispanic women: the Women's Health Initiative SHARe Study. (PubMed id 22131368)1 Chen C.T....Franceschini N. (2012)
- Persistence of the cell-cycle checkpoint kinase Wee1 in SadA- and SadB-deficient neurons disrupts neuronal polarity. (PubMed id 20026642)2 MA1ller M....PA1schel A.W. (2010)
|
External Searches for BRSK1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing BRSK1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing BRSK1 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing BRSK1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for BRSK1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for BRSK1 gene:
Search GeneIP for patents involving BRSK1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for BRSK1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for BRSK1 | | OriGene shRNA RFP for BRSK1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BRSK1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BRSK1 | | | OriGene Protein Over-expression Lysate for BRSK1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for BRSK1 | | OriGene 3'-UTR Clone for BRSK1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BRSK1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BRSK1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for BRSK1 | | OriGene Custom Protein Services for BRSK1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat BRSK1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BRSK1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BRSK1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BRSK1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BRSK1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BRSK1 |
| |
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| | Antibodies & Assays for BRSK1 |
| | | | Search Tocris compounds for BRSK1 |
| |  |  |  |  | | | | |
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 | | | BRSK1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BRSK1 |
|  |  |  | | | | ThermoFisher Antibodies for BRSK1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BRSK1 |
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