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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

BRPF3 Gene

protein-coding   GIFtS: 51
GCID: GC06P036213

bromodomain and PHD finger containing, 3
  Search for BRPF3
in
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our new
 Human Malady Compendium 
Biological research products
for BRPF3    

Aliases
for BRPF3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Bromodomain And PHD Finger Containing, 31 2
KIAA12861 3
Bromodomain And PHD Finger-Containing Protein 32

External Ids:    HGNC: 142561   Entrez Gene: 271542   Ensembl: ENSG000000960707   UniProtKB: Q9ULD43   

Export aliases for BRPF3 gene to outside databases

Previous GC identifers: GC06P036167 GC06P036211 GC06P036272 GC06P035884


Summaries
for BRPF3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: BRPF3_HUMAN, Q9ULD4
Function: Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity




Genomic Views
for BRPF3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the BRPF3 gene promoter:
         FOXF2   p300   Tal-1beta   GATA-1   E47   MZF-1   PPAR-gamma1   POU2F1   POU2F1a   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: BRPF3 promoter sequence
   Search SABiosciences Chromatin IP Primers for BRPF3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BRPF3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21   Ensembl cytogenetic band:  6p21.31   HGNC cytogenetic band: 6p21.31

BRPF3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BRPF3 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P036213:  view genomic region     (about GC identifiers)

Start:
 36,164,521 bp from pter      End:
 36,200,567 bp from pter
Size:
 36,047 bases      Orientation:
 plus strand

Proteins
for BRPF3 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: BRPF3_HUMAN, Q9ULD4 (See protein sequence)
Recommended Name: Bromodomain and PHD finger-containing protein 3  
Size: 1205 amino acids; 135745 Da
Subunit: Component of the MOZ/MORF complex composed at least of ING5, KAT6A, KAT6B, MEAF6 and one of BRPF1, BRD1/BRPF2
and BRPF3
Sequence caution: Sequence=BAA86600.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for BRPF3:
3PFS (3D)    
Secondary accessions: A6NJE2 Q5R3K8

Explore the universe of human proteins at neXtProt for BRPF3: NX_Q9ULD4

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9ULD4

    • BRPF3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_056510.2  
    ENSEMBL proteins: 
     ENSP00000350267   ENSP00000345419   ENSP00000434501   ENSP00000416842   ENSP00000410669  
     ENSP00000413655   ENSP00000437087   ENSP00000436504   ENSP00000411558   ENSP00000431894  
     ENSP00000413022   ENSP00000445352   ENSP00000387368  
    Reactome Protein details: Q9ULD4
    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: BRPF3
    OriGene Custom Protein Services for BRPF3 
    GenScript Custom Purified and Recombinant Proteins Services for BRPF3
    Novus Biologicals BRPF3 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for BRPF3

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0005829cytosol TAS--
    GO:0070776MOZ/MORF histone acetyltransferase complex IDA16387653


    BRPF3 for ontologies           About GeneDecksing



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    Uscn Antibodies for BRPF3
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    Assay Products for BRPF3: 
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    Uscn ELISAs and CLIAs for BRPF3

    Protein Domains /
    Families
    for BRPF3 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    BRPF3 for domains           About GeneDecksing

    5/9 InterPro domains/families (see all 9):
     IPR019786 Zinc_finger_PHD-type_CS
     IPR001965 Znf_PHD
     IPR018359 Bromodomain_CS
     IPR001487 Bromodomain
     IPR013083 Znf_RING/FYVE/PHD

    Graphical View of Domain Structure for InterPro Entry Q9ULD4

    ProtoNet protein and cluster: Q9ULD4

    3 Blocks protein families:
    IPB000313 PWWP domain
    IPB001487 Bromodomain signature
    IPB001965 Zn-finger-like


    UniProtKB/Swiss-Prot: BRPF3_HUMAN, Q9ULD4
    Similarity: Contains 1 bromo domain
    Similarity: Contains 1 PHD-type zinc finger
    Similarity: Contains 1 PWWP domain


    Function
    for BRPF3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: BRPF3_HUMAN, Q9ULD4
    Function: Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity

    miRNA
    Products:            		miRTarBase miRNAs that target BRPF3:
    hsa-mir-155 (MIRT001563)

    OriGene 3'-UTR Clone: BRPF3
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BRPF3
    8/63 QIAGEN miScript miRNA Assays for microRNAs that regulate BRPF3 (see all 63):
    hsa-miR-142-5p hsa-miR-4328 hsa-miR-513a-5p hsa-miR-218-1* hsa-miR-1245 hsa-miR-128 hsa-miR-16-1* hsa-miR-3653
    SwitchGear 3'UTR luciferase reporter plasmid: BRPF3 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BRPF3 (see all 7)
    OriGene shRNA RFP: BRPF3
    OriGene siRNA: BRPF3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BRPF3

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for BRPF3

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BRPF3 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BRPF3
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: BRPF3 (NM_015695)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BRPF3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BRPF3 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for BRPF3
    Search LifeMap BioReagents cell lines for BRPF3

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BRPF3

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI17474147
    GO:0008270zinc ion binding IEA--


    BRPF3 for ontologies           About GeneDecksing


    Animal Models:
         1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Brpf3):
     mortality/aging 

    BRPF3 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for BRPF3 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Platelet degranulation
    		Platelet degranulation 1.00
    		Response to elevated platelet cytosolic Ca2+0.94
    2Platelet activation, signaling and aggregation
    		Platelet activation, signaling and aggregation1.00
    		Hemostasis0.43

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    4        Reactome Pathways for BRPF3
        Hemostasis
    Platelet degranulation
    Platelet activation, signaling and aggregation
    Response to elevated platelet cytosolic Ca2+



    BRPF3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BRPF3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 21)

    5/21 Interacting proteins for BRPF3 (Q9ULD41, 2, 3 ENSP000003502674) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ABL1P005192, 3, ENSP000003614234MINT-8110083 I2D: score=3 STRING: ENSP00000361423
    FYNP062412, 3, ENSP000003576564MINT-8110983 I2D: score=3 STRING: ENSP00000357656
    PIK3R1P279862, 3, ENSP000002743354MINT-8111739 I2D: score=3 STRING: ENSP00000274335
    NCK1P163331, 3, ENSP000002889864EBI-1753470,EBI-3448658 I2D: score=2 STRING: ENSP00000288986
    ING5Q8WYH83, ENSP000003221424I2D: score=1 STRING: ENSP00000322142
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002576platelet degranulation TAS--
    GO:0007596blood coagulation TAS--
    GO:0030168platelet activation TAS--
    GO:0043966histone H3 acetylation IDA16387653


    BRPF3 for ontologies           About GeneDecksing



    Drugs & Compounds
    for BRPF3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for BRPF3
    Search CenterWatch for drugs/clinical trials and news about BRPF3 

    Transcripts
    for BRPF3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for BRPF3 gene: 
    NM_015695.2  

    Unigene Cluster for BRPF3:

    Bromodomain and PHD finger containing, 3
    Hs.520096  [show with all ESTs]
    Unigene Representative Sequence: NM_015695
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000357641(uc003olv.4 uc010jwb.3 uc011dtj.2 uc010jwc.3 uc011dtk.2 uc010jwd.3)
    ENST00000339717 ENST00000534694 ENST00000449261 ENST00000446974 ENST00000454960
    ENST00000532330 ENST00000534400 ENST00000441123 ENST00000527657 ENST00000532538
    ENST00000441730 ENST00000543502 ENST00000443324

    miRNA
    Products:             		 OriGene 3'-UTR Clone: BRPF3
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BRPF3
    8/63 QIAGEN miScript miRNA Assays for microRNAs that regulate BRPF3 (see all 63):
    hsa-miR-142-5p hsa-miR-4328 hsa-miR-513a-5p hsa-miR-218-1* hsa-miR-1245 hsa-miR-128 hsa-miR-16-1* hsa-miR-3653
    SwitchGear 3'UTR luciferase reporter plasmid: BRPF3 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BRPF3 (see all 7)
    OriGene shRNA RFP: BRPF3
    OriGene siRNA: BRPF3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BRPF3
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BRPF3 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BRPF3
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: BRPF3 (NM_015695)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BRPF3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BRPF3 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BRPF3
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat BRPF3
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BRPF3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BRPF3

    Additional cDNA sequence: 

    AB033112.1 AK000751.1 AK025134.1 AK025224.1 AK074362.1 AK097773.1 AK123574.1 AK172787.1 
    BC033652.2 BC039615.1 BC117387.1 BC143917.1 BC143918.1 BC143919.1 

    9 DOTS entries:

    DT.452215  DT.92011568  DT.91703586  DT.102836443  DT.121376037  DT.121376044  DT.97840963  DT.97840965 
    DT.99952720 

    24/168 AceView cDNA sequences (see all 168):

    AB033112 AA704529 BM677765 BC033652 BP873496 AI435098 BQ233619 AI963373 
    AA626847 BG033814 AI087007 AA868396 AK172787 AL047079 AA333129 BC039615 
    AA912379 AA848024 BU509365 AI369352 AK000751 N66794 N74005 AA374195 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for BRPF3 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13 ^ 14
    SP1:                                                                    -                                                                     
    SP2:                                                                                                              -     -     -     -         
    SP3:                                                                    -                                                                     
    SP4:                                                                                                              -                           
    SP5:                                                                                                              -                           


    ECgene alternative splicing isoforms for BRPF3

    Expression
    for BRPF3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    BRPF3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ATGCTCTATT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    BRPF3 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    9 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    LimbZeugopodMesenchymal Condensate CellsBone, Cartilage
    Neural TubeNeural TubeSpinal Neural Tube CellsNeural Ectoderm
    BoneEndochondral Facial BonesBone
    BoneStylopod Long BoneBone
    BoneThoracic RibBone
    BoneZeugopod Long BoneBone
    CartilageMeckel's CartilageCartilage
    LimbZeugopodLimb
    Spinal CordPresumptive Spinal CordSpinal Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See BRPF3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for BRPF3

    SOURCE GeneReport for Unigene cluster: Hs.520096
        SABiosciences Expression via Pathway-Focused PCR Array including BRPF3: 
              Epigenetic Chromatin Remodeling Factors in human mouse rat

    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BRPF3
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BRPF3

    Orthologs
    for BRPF3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for BRPF3 gene from 8/24 species (see all 24)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves BRPF31 bromodomain and PHD finger containing, 3 76.32(n)
    80.61(a)    		   421182  XM_419262.3  XP_419262.3 
    lizard
    (Anolis carolinensis)    		 Reptilia BRPF36
    		 --
    		 79(a)
    		 1 ↔ 1
    		 GL343382.1(546335-573088)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia BX750878.12   -- 77.99(n)    BX750878.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii brpf31 bromodomain and PHD finger containing, 3 61.15(n)
    59.51(a)    		   100149254  XM_001922163.3  XP_001922198.2 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG18453   -- 42(a)     --
    worm
    (Caenorhabditis elegans)    		 Secernentea lin-493 zinc-finger protein 28(a)   IV(8620948-8625841)   --
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT3G147406
    		 RING/FYVE/PHD zinc finger-containing protein
    		 23(a)
    		 1 → many
    		 3(4952004-4953423)
    rice
    (Oryza sativa)    		 Liliopsida --
    		 PHD-finger domain containing protein, putative, ex...
    		 11(a)
    		 1 → many
    		 1(4430532-4432679)


    ENSEMBL Gene Tree for BRPF3 (if available)
    TreeFam Gene Tree for BRPF3 (if available) 

    Paralogs
    for BRPF3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for BRPF3 gene
    PHF172  BRPF12  BRD12  MLLT102  PHF142  PHF152  PHF162  MLLT62  
    9 SIMAP similar genes for BRPF3 using alignment to 12 protein entries:     BRPF3_HUMAN (see all proteins):
    DKFZp586E1619    DKFZp686F0325    BRPF1    BRD1    DKFZp434B094    AF10
    MLLT10    MLL/AF10 fusion    MLLT6

    BRPF3 for paralogs           About GeneDecksing



    Genomic Variants
    for BRPF3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/582 NCBI SNPs in BRPF3 are shown (see all 582)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 6 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1469519731,2
    		--36162642(+) CACATC/GCATTA 1 -- us2k10--------
    rs1173418831,2
    		--36162684(+) AATCGT/CTGACT 1 -- us2k11Minor allele frequency- C:0.01EA 120
    rs105339291,2
    		C--36162814(+) GAAATAA/-AAGTT 1 -- us2k11Minor allele frequency- -:0.50NA 2
    rs1412558561,2
    		C,--36162814(+) GAAAT-/AAAAGTT 1 -- us2k10--------
    rs1929665471,2
    		--36162862(+) TTTTAA/GTAGTT 1 -- us2k10--------
    rs734136881,2
    		C,--36162866(+) AATAGC/TTTCTG 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1379450351,2
    		--36162870(+) GTTTCC/TGTTAG 1 -- us2k10--------
    rs1853453441,2
    		--36163035(+) TACTAG/TTTCAT 1 -- us2k10--------
    rs1434361091,2
    		--36163040(+) TTTCAC/TCTTCA 1 -- us2k10--------
    rs1457390581,2
    		--36163057(+) TCAAAA/CCATTG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for BRPF3 (36164521 - 36200567 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for BRPF3: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BRPF3
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    Disorders / Diseases
    for BRPF3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    		   --

    Publications
    for BRPF3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for BRPF3 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with BRPF3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10574462)1, 2, 3 Nagase T.... Ohara O. (1999)
    2. Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes. (PubMed id 18794358)1, 2 Ullah M....Yang X.-J. (2008)
    3. ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation. (PubMed id 16387653)1, 2 Doyon Y.... Cote J. (2006)
    4. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    5. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    6. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    7. Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (2009)
    8. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
    9. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    10. Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. (PubMed id 17474147)1 Wu C....Li S.S. (2007)

    External Searches for BRPF3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    Genome Databases showing BRPF3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 27154 HGNC: 14256 AceView: BRPF3 Ensembl:ENSG00000096070 euGenes: HUgn27154
    ECgene: BRPF3 H-InvDB: BRPF3

    Other Databases showing BRPF3 gene

    (According to HUGE)
    About This Section
    HUGE: KIAA1286

    Specialized Databases showing BRPF3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for BRPF3 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for BRPF3 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for BRPF3 gene:
    Search GeneIP for patents involving BRPF3

    GeneCards and IP:
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