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BROX Gene

protein-coding   GIFtS: 41
GCID: GC01P222886

BRO1 Domain And CAAX Motif Containing

(Previous name: chromosome 1 open reading frame 58)
(Previous symbol: C1orf58)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
BRO1 Domain And CAAX Motif Containing1 2     BRO1 Domain-Containing Protein BROX2
C1orf581 2 3     BROFTI3
BRO1 Domain Containing Protein1     BRO1 Domain- And CAAX Motif-Containing Protein3
Chromosome 1 Open Reading Frame 581     

External Ids:    HGNC: 265121   Entrez Gene: 1483622   Ensembl: ENSG000001628197   UniProtKB: Q5VW323   

Export aliases for BROX gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for BROX Gene:
BROX (BRO1 domain and CAAX motif containing) is a protein-coding gene.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_004487.20  NC_018912.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for BROX
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for BROX

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BROX


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q41   Ensembl cytogenetic band:  1q41   HGNC cytogenetic band: 1q41

BROX Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BROX gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P222886:  view genomic region     (about GC identifiers)

Start:
222,885,895 bp from pter      End:
222,908,538 bp from pter
Size:
22,644 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: BROX_HUMAN, Q5VW32 (See protein sequence)
Recommended Name: BRO1 domain-containing protein BROX precursor  
Size: 411 amino acids; 46476 Da
Subunit: Interacts with CHMP4B
Selected PDB 3D structures from and Proteopedia for BROX (see all 7):
3R9M (3D)        3ULY (3D)        3UM0 (3D)        3UM1 (3D)        3UM2 (3D)        3UM3 (3D)    
Secondary accessions: Q96MG1

Explore the universe of human proteins at neXtProt for BROX: NX_Q5VW32

Explore proteomics data for BROX at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys155, Lys334
  • Modification sites at PhosphoSitePlus

  • See BROX Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001275508.1  NP_001275509.1  NP_001275510.1  NP_653296.2  

    ENSEMBL proteins: 
     ENSP00000343742   ENSP00000398862   ENSP00000441080   ENSP00000440041  

    BROX Human Recombinant Protein Products:

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    Novus Biologicals BROX Lysate
    Browse Sino Biological Recombinant Proteins
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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for BROX

     
    Search eBioscience for Proteins for BROX 

     
    antibodies-online proteins for BROX (4 products) 

     
    antibodies-online peptides for BROX

    BROX Antibody Products:

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    BROX Assay Products:

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    Cloud-Clone Corp. ELISAs for BROX
    Cloud-Clone Corp. CLIAs for BROX
    Search eBioscience for ELISAs for BROX 
    antibodies-online kits for BROX (3 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR004328 BRO1_dom

    Graphical View of Domain Structure for InterPro Entry Q5VW32

    ProtoNet protein and cluster: Q5VW32

    UniProtKB/Swiss-Prot: BROX_HUMAN, Q5VW32
    Similarity: Belongs to the BROX family
    Similarity: Contains 1 BRO1 domain


    Find genes that share domains with BROX           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for BROX

    miRNA
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    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat BROX

    Gene Editing
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    Clone
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    OriGene ORF clones in mouse, rat for BROX
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: BROX (NM_144695)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BROX
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BROX

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for BROX 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BROX


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    BROX_HUMAN, Q5VW32: Membrane; Lipid-anchor (Potential)

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016020membrane IEA--
    GO:0070062extracellular vesicular exosome IDA19056867

    Find genes that share ontologies with BROX           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for BROX
    Interactions:

        Search GeneGlobe Interaction Network for BROX

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    Selected Interacting proteins for BROX (ENSP000003437424) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CHMP4BENSP000002174024STRING: ENSP00000217402
    CHMP5ENSP000002235004STRING: ENSP00000223500
    DPP3ENSP000003537014STRING: ENSP00000353701
    LSM3ENSP000003021604STRING: ENSP00000302160
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for BROX



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for BROX gene (4 alternative transcripts): 
    NM_001288579.1  NM_001288580.1  NM_001288581.1  NM_144695.3  

    Unigene Cluster for BROX:

    BRO1 domain and CAAX motif containing
    Hs.552608  [show with all ESTs]
    Unigene Representative Sequence: AK094916
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000340934(uc001hnq.1 uc010put.1) ENST00000496267(uc001hnp.1)
    ENST00000426638 ENST00000473962 ENST00000469236 ENST00000489191 ENST00000539697(uc010puv.1)
    ENST00000537020(uc010puu.1)
    miRNA
    Products:
         
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    Search for qRT-PCR Assays for microRNAs that regulate BROX
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for BROX
    Predesigned siRNA for gene silencing in human, mouse, rat BROX
    Clone
    Products:
         
    OriGene clones in human, mouse for BROX (see all 6)
    OriGene ORF clones in mouse, rat for BROX
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: BROX (NM_144695)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BROX
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BROX
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for BROX
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat BROX
      QuantiTect SYBR Green Assays in human, mouse, rat BROX
      QuantiFast Probe-based Assays in human, mouse, rat BROX

    Additional mRNA sequence: 

    AB276123.1 AK056983.1 AK094916.1 AK293974.1 AK304445.1 AK315930.1 BC053552.1 BC105293.1 
    BC113635.1 BC113637.1 BC143811.1 

    9 DOTS entries:

    DT.97797499  DT.97809992  DT.91691294  DT.100001492  DT.97826885  DT.100030193  DT.99936112  DT.99992366 
    DT.91811207 

    Selected AceView cDNA sequences (see all 114):

    AI978719 BX107070 AA444170 BX107721 AI911339 AA953958 CB305418 AA443374 
    AA280827 BG621722 CD677978 AW068491 AI624539 BM983079 CB850504 BQ921631 
    AI024071 AI753272 BE672496 AW768840 AI399715 CN478796 BM722436 CA436494 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for BROX    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15
    SP1:              -           -                                                                           
    SP2:                                                                                                      
    SP3:                                                                                                      


    ECgene alternative splicing isoforms for BROX

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    BROX expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGAGACTTT
    BROX Expression
    About this image

    BROX Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    BROX Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.552608
        Custom PCR Arrays for BROX
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BROX

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for BROX gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Brox1 , 5 BRO1 domain and CAAX motif containing1, 5 85.81(n)1
    91.73(a)1
      15
    716781  NM_027861.21  NP_082137.11 
     1832763425 
    chicken
    (Gallus gallus)
    Aves BROX1 BRO1 domain and CAAX motif containing 79.56(n)
    86.37(a)
      421334  XM_004935306.1  XP_004935363.1 
    lizard
    (Anolis carolinensis)
    Reptilia BROX6
    BRO1 domain and CAAX motif containing
    86(a)
    1 ↔ 1
    1(244514446-244524229)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia brox1 BRO1 domain and CAAX motif containing 73.64(n)
    82.24(a)
      100125017  NM_001102942.1  NP_001096412.1 
    zebrafish
    (Danio rerio)
    Actinopterygii brox1 BRO1 domain and CAAX motif containing 67.32(n)
    73.9(a)
      492786  NM_001007427.1  NP_001007428.1 
    worm
    (Caenorhabditis elegans)
    Secernentea B0507.21 B0507.2 51.82(n)
    40.15(a)
      179255  NM_072860.5  NP_505261.2 


    ENSEMBL Gene Tree for BROX (if available)
    TreeFam Gene Tree for BROX (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for BROX (see all 434)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs727401161,2
    C,F--229679442(+) CAGAAC/TGGGTA 1 -- us2k10--------
    rs1390241491,2
    --229679473(+) GGCTAC/TAGTAT 1 -- us2k10--------
    rs765512961,2
    C,F--229679521(+) CATTTG/CTCTAA 1 -- us2k11Minor allele frequency- C:0.23EA 120
    rs1499128371,2
    --229679565(+) AAGCAC/TTCTGT 1 -- us2k10--------
    rs1116041401,2
    C,F--229679606(+) AAATCC/TCAGAT 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1405483211,2
    C--229679820(+) CTACAA/GGCGAT 1 -- us2k10--------
    rs731248911,2
    C--229679965(+) GGATGG/CGGGGT 1 -- us2k11Minor allele frequency- C:0.50WA 2
    rs750831181,2
    C,F--229679975(+) TGGGGG/AAGGCC 1 -- us2k11Minor allele frequency- A:0.04EA 120
    rs731248931,2
    C,F--229680011(+) TCATAC/TTCAGT 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1151542121,2
    C,F--229680070(+) GTTTGC/TAAACA 1 -- us2k11Minor allele frequency- T:0.12WA 118

    HapMap Linkage Disequilibrium report for BROX (222885895 - 222908538 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for BROX:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2668629CNV Deletion23128226
    nsv873205CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing BROX
    DNA2.0 Custom Variant and Variant Library Synthesis for BROX

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for BROX gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with BROX)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Brox, a novel farnesylated Bro1 domain-containing protein that associates with charged multivesicular body protein 4 (CHMP4). (PubMed id 18190528)1, 2, 3 Ichioka F.... Maki M. (FEBS J. 2008)
    2. Towards complete sets of farnesylated and geranylgeranylated proteins. (PubMed id 17411337)1, 2 Maurer-Stroh S....Eisenhaber F. (PLoS Comput. Biol. 2007)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    5. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    7. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    8. Structure of the Bro1 domain protein BROX and functional analyses of the ALIX Bro1 domain in HIV-1 budding. (PubMed id 22162750)1 Zhai Q....Hill C.P. (PLoS ONE 2011)
    9. The Phe105 loop of Alix Bro1 domain plays a key role in HIV-1 release. (PubMed id 21889351)2 Sette P....Bouamr F. (Structure 2011)
    10. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 148362 HGNC: 26512 AceView: FLJ32421.1 Ensembl:ENSG00000162819 euGenes: HUgn148362
    ECgene: BROX H-InvDB: BROX

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for BROX Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for BROX gene:
    Search GeneIP for patents involving BROX

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
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     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for BROX  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for BROX  
     OriGene MassSpec for BROX   OriGene clones in human, mouse for BROX  
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     Block miRNA regulation of human, mouse, rat BROX using miScript Target Protectors SeqTarget long-range PCR primers for resequencing BROX
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BROX Predesigned siRNA for gene silencing in human, mouse, rat BROX
     QuantiFast Probe-based Assays in human, mouse, rat BROX QuantiTect SYBR Green Assays in human, mouse, rat BROX
     Custom PCR Arrays for BROX Search Chromatin IP Primers for BROX
     Pre-validated RT2 qPCR Primer Assay in human, mouse / rat BROX  Search GeneGlobe Interaction Network for BROX
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     GenScript Custom Purified and Recombinant Proteins Services for BROX GenScript cDNA clones with any tag delivered in your preferred vector for BROX
     GenScript Custom Assay Services for BROX GenScript Custom overexpressing Cell Line Services for BROX
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
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     Novus Tissue Slides
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     Browse SwitchGear 3'UTR luciferase reporter plasmids for BROX
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     Browse compounds at ApexBio
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      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for BROX
     antibodies-online antibodies for BROX
     antibodies-online kits for BROX (3 products)
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     antibodies-online proteins for BROX (4 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

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