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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

BRK1 Gene

protein-coding   GIFtS: 46
GCID: GC03P010166

BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit

(Previous name: chromosome 3 open reading frame 10)
(Previous symbol: C3orf10)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit1 2     SCAR/WAVE Actin-Nucleating Complex Subunit1
C3orf101 2 3     MDS0272
Haematopoietic Stem/Progenitor Cell Protein 3001 2     BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit, Homolog2
BRICK11     hHBrk12
Chromosome 3 Open Reading Frame 101     Probable Protein BRICK12
Homolog (Arabidopsis Thaliana)1     Protein BRICK12

External Ids:    HGNC: 230571   Entrez Gene: 558452   Ensembl: ENSG000002549997   OMIM: 6111835   UniProtKB: Q8WUW13   

Export aliases for BRK1 gene to outside databases

Previous GC identifers: GC03P010162 GC03P010163 GC03P010164 GC03P010165


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for BRK1 Gene: 
BRK1 (BRICK1, SCAR/WAVE actin-nucleating complex subunit) is a protein-coding gene. Diseases associated with BRK1 include lung squamous cell carcinoma, and clear cell renal cell carcinoma, and among its related super-pathways are Regulation of actin cytoskeleton and Regulation of actin dynamics for phagocytic cup formation.

UniProtKB/Swiss-Prot: BRK1_HUMAN, Q8WUW1
Function: Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the
Arp2/3 complex

Gene Wiki entry for BRK1 (C3orf10) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.2  NT_022517.18  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for BRK1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBRK1 promoter sequence
   Search SABiosciences Chromatin IP Primers for BRK1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BRK1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p25.3   Ensembl cytogenetic band:  3p25.3   HGNC cytogenetic band: 3p25.3

BRK1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BRK1 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P010166:  view genomic region     (about GC identifiers)

Start:
10,157,276 bp from pter      End:
10,168,874 bp from pter
Size:
11,599 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: BRK1_HUMAN, Q8WUW1 (See protein sequence)
Recommended Name: Protein BRICK1  
Size: 75 amino acids; 8745 Da
Subunit: Homotrimer when in free form. Directly interacts with WASF2. Component of the WAVE1 complex composed of
ABI2, CYFIP1 or CYFIP2, BRK1, NCKAP1 and WASF1/WAVE1. Within the complex, a heterdimer containing NCKAP1 and
CYFIP1 interacts with a heterotrimer formed by WAVE1, ABI2 and BRK1
Subcellular location: Cytoplasm, cytoskeleton (By similarity)
Sequence caution: Sequence=AAF28978.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for BRK1:
3P8C (3D)    
Secondary accessions: B2R5E2 Q9P082
Alternative splicing: 2 isoforms:  Q8WUW1-1   Q8WUW1-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for BRK1: NX_Q8WUW1

Explore proteomics data for BRK1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8WUW1

  • BRK1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    BRK1 Protein Expression
    REFSEQ proteins: NP_060932.2  
    ENSEMBL proteins: 
     ENSP00000432472   ENSP00000444659  
    Reactome Protein details: Q8WUW1
    Human Recombinant Protein Products for BRK1: 
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    Novus Biologicals BRK1 Protein
    Novus Biologicals BRK1 Lysate
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--
    GO:0005856cytoskeleton IEA--

    BRK1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ProtoNet protein and cluster: Q8WUW1

    UniProtKB/Swiss-Prot: BRK1_HUMAN, Q8WUW1
    Similarity: Belongs to the BRK1 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BRK1_HUMAN, Q8WUW1
    Function: Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the
    Arp2/3 complex

    Phenotypes:
         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Brk1):

     cellular  embryogenesis  growth/size  mortality/aging  reproductive system 

    BRK1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for BRK1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for BRK1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for BRK1 
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    hsa-miR-498 hsa-miR-146b-3p hsa-miR-186* hsa-miR-15a hsa-miR-497 hsa-miR-3647-3p hsa-miR-1251 hsa-miR-424
    SwitchGear 3'UTR luciferase reporter plasmidBRK1 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for BRK1 About   (see all 6)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Regulation of Actin Cytoskeleton
    Regulation of Actin Cytoskeleton0.57
    Regulation of actin cytoskeleton0.57
    2Fcgamma receptor (FCGR) dependent phagocytosis
    Regulation of actin dynamics for phagocytic cup formation0.80
    Fcgamma receptor (FCGR) dependent phagocytosis0.80
    3Immune System
    Immune System0.56
    Innate Immune System0.50
    4Cytoskeleton remodeling CDC42 in cellular processes
    G-protein signaling RAC1 in cellular process0.37
    5CDC42 signaling events
    RAC1 signaling pathway0.34

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 EMD Millipore Pathway for BRK1
        G-protein signaling RAC1 in cellular process


    1 GeneGo (Thomson Reuters) Pathway for BRK1
        G-protein signaling RAC1 in cellular process

    3 BioSystems Pathways for BRK1
        Regulation of Actin Cytoskeleton
    ErbB1 downstream signaling
    RAC1 signaling pathway

    4        Reactome Pathways for BRK1
        Regulation of actin dynamics for phagocytic cup formation
    Fcgamma receptor (FCGR) dependent phagocytosis
    Immune System
    Innate Immune System


    1         Kegg Pathway  (Kegg details for BRK1):
        Regulation of actin cytoskeleton


    BRK1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BRK1

    5/7 Interacting proteins for BRK1 (Q8WUW12, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PFDN1O609252, 3MINT-8265720 I2D: score=2 
    WASF1Q925582, 3MINT-17058 I2D: score=2 
    ABI1Q8IZP03I2D: score=1 
    CYFIP2Q96F073I2D: score=1 
    NCK1P163333I2D: score=1 
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001701in utero embryonic development IEA--
    GO:0008284positive regulation of cell proliferation IEA--
    GO:0030036actin cytoskeleton organization IEA--
    GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis TAS--
    GO:0045087innate immune response TAS--

    BRK1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for BRK1

    Search CenterWatch for drugs/clinical trials and news about BRK1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for BRK1 gene: 
    NM_018462.4  

    Unigene Cluster for BRK1:

    BRICK1, SCAR/WAVE actin-nucleating complex subunit
    Hs.649307  [show with all ESTs]
    Unigene Representative Sequence: BF102725
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000530758(uc003bvb.3) ENST00000256463
    miRNA
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    hsa-miR-498 hsa-miR-146b-3p hsa-miR-186* hsa-miR-15a hsa-miR-497 hsa-miR-3647-3p hsa-miR-1251 hsa-miR-424
    SwitchGear 3'UTR luciferase reporter plasmidBRK1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BRK1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BRK1

    Additional mRNA sequence: 

    AF161418.1 AK290580.1 AK312155.1 AY148219.1 AY148220.1 BC001067.1 BC007929.1 BC019303.1 
    BC061515.1 

    24 DOTS entries:

    DT.454565  DT.100880746  DT.92047200  DT.97760294  DT.91979578  DT.95231276  DT.91908712  DT.91786041 
    DT.100880742  DT.120922768  DT.91763462  DT.91846616  DT.92439090  DT.120922748  DT.91855549  DT.100880745 
    DT.100880748  DT.120922764  DT.100707706  DT.101982322  DT.120922758  DT.85104605  DT.92380635  DT.95231265 

    24/582 AceView cDNA sequences (see all 582):

    AA360480 BX400053 BM423400 BU535416 AI868778 AI139777 BU681150 BQ420540 
    AA316211 BM553974 BU660673 AW072638 AI401575 BQ084571 AY148219 CR605267 
    BQ631333 BQ064700 BQ953281 BU790252 BG574246 AI634611 W76073 CA435036 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    BRK1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCTGGCAAT
    BRK1 Expression
    About this image


    See BRK1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for BRK1

    SOURCE GeneReport for Unigene cluster: Hs.649307
        SABiosciences Custom PCR Arrays for BRK1
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for BRK1 gene from 4/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Brk11 , 5 RIKEN cDNA 6720456B07 gene5
    BRICK1, SCAR/WAVE actin-nucleating complex subunit1
    94.67(n)1
    98.67(a)1
      6 (52.81 cM)5
    1013141  NM_133937.11  NP_598698.11 
     1136047725 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.109062 Xenopus laevis transcribed sequences 83.4(n)    BJ080684.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.139252 Danio rerio, Similar to uncharacterized hematopoietic more 74.81(n)    BC046048.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta HSPC3001 CG30173-PA 69.52(n)
    77.14(a)
      246497  NM_166648.2  NP_726400.1 


    ENSEMBL Gene Tree for BRK1 (if available)
    TreeFam Gene Tree for BRK1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for BRK1 gene

    BRK1 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for BRK1
    PGOHUM00000257957 PGOHUM00000260940


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/322 SNPs in BRK1 are shown (see all 322)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1123482221,2
    C,F--10155487(+) CTCACG/ACCTGT 1 -- us2k13Minor allele frequency- A:0.20NA WA CSA 5
    rs609906461,2
    C--10155584(+) TCTCTA/GGTAAA 1 -- us2k12Minor allele frequency- G:0.33NA CSA 3
    rs361261141,2
    C--10155587(+) AAAAA-/ATTAGC 1 -- us2k10--------
    rs586986441,2
    C,F--10155611(+) CTGTGA/TGTGGT 1 -- us2k12Minor allele frequency- T:0.33NA CSA 3
    rs1493789851,2
    --10155823(+) ACTACA/CTTAGC 1 -- us2k10--------
    rs1924718431,2
    --10155827(+) CCTTAA/GCAAAG 1 -- us2k10--------
    rs170324031,2
    C,F,H--10155882(+) CATTTT/CTCCAT 1 -- us2k116Minor allele frequency- C:0.03NA NS EA WA 1222
    rs1858030611,2
    --10155918(+) CCAGGA/CAGGGT 1 -- us2k10--------
    rs1875882701,2
    C--10155979(+) CTTGAA/GGTCAG 1 -- us2k10--------
    rs1167746331,2
    F--10156176(+) GCATTA/CACAGA 1 -- us2k11Minor allele frequency- C:0.08NA 120

    HapMap Linkage Disequilibrium report for BRK1 (10157276 - 10168874 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for BRK1:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv809e201CNV Deletion23290073
    nsv436362CNV Deletion17901297
    nsv436869CNV Insertion17901297
    esv4117CNV Complex18987735

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611183    OMIM disorders: --

    7 diseases for BRK1:    About MalaCards
    lung squamous cell carcinoma    clear cell renal cell carcinoma    von hippel-lindau disease    gout
    renal cell carcinoma    multiple sclerosis    squamous cell carcinoma


    BRK1 for disorders           About GeneDecksing


    Export disorders for BRK1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for BRK1 gene, integrated from 9 sources (see all 25):
    (articles sorted by number of sources associating them with BRK1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Solid renal tumor severity in von Hippel Lindau disease is related to germline deletion length and location. (PubMed id 14695531)1, 3 Maranchie J.K....Linehan W.M. (2004)
    3. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    4. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    5. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
    6. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
    10. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55845 HGNC: 23057 AceView: C3orf10 Ensembl:ENSG00000254999 euGenes: HUgn55845
    ECgene: BRK1 Kegg: 55845 H-InvDB: BRK1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for BRK1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for BRK1 gene:
    Search GeneIP for patents involving BRK1

    GeneCards and IP:
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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