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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

BRIX1 Gene

protein-coding   GIFtS: 50
GCID: GC05P034953

BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)

(Previous name: brix domain containing 2 )
(Previous symbol: BXDC2)
 Explore 2 diseases affiliated with
BRIX1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for BRIX1    

Aliases
for BRIX1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
BRX1, Biogenesis Of Ribosomes, Homolog (S. Cerevisiae)1 2     Brix Domain-Containing Protein 22 3
BRIX1 2 3     FLJ111001
BXDC21 2 3     Ribosome Biogenesis Protein BRX1 Homolog2
Brix Domain Containing 21 2     

External Ids:    HGNC: 241701   Entrez Gene: 552992   Ensembl: ENSG000001134607   UniProtKB: Q8TDN63   

Export aliases for BRIX1 gene to outside databases


Summaries
for BRIX1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: BRX1_HUMAN, Q8TDN6
Function: Required for biogenesis of the 60S ribosomal subunit

Gene Wiki entry for BRIX1 (BXDC2)


Genomic Views
for BRIX1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.1  NT_006576.16  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for BRIX1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: BRIX1 promoter sequence
   Search SABiosciences Chromatin IP Primers for BRIX1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BRIX1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5p13.2   Ensembl cytogenetic band:  5p13.2   HGNC cytogenetic band: 5p13.2

BRIX1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BRIX1 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P034953:  view genomic region     (about GC identifiers)

Start:
 34,915,481 bp from pter      End:
 34,926,101 bp from pter
Size:
 10,621 bases      Orientation:
 plus strand

Proteins
for BRIX1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: BRX1_HUMAN, Q8TDN6 (See protein sequence)
Recommended Name: Ribosome biogenesis protein BRX1 homolog  
Size: 353 amino acids; 41401 Da
Subcellular location: Nucleus, nucleolus
Secondary accessions: A8K0P5 Q3ZTT4 Q8N453 Q96DH1

Explore the universe of human proteins at neXtProt for BRIX1: NX_Q8TDN6

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8TDN6

    • BRIX1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_060791.3  
    ENSEMBL proteins: 
     ENSP00000338862  

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    Novus Biologicals BRIX1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for BRIX1

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--


    BRIX1 for ontologies           About GeneDecksing



    BRIX1 Antibody Products: 
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    Uscn Antibodies for BRIX1
    Search ThermoFisher Antibodies for BRIX1

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    GenScript Custom Assay Services for BRIX1
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    Uscn ELISAs and CLIAs for BRIX1

    Protein Domains /
    Families
    for BRIX1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    BRIX1 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR007109 Brix
     IPR004154 Anticodon-bd
     IPR026532 BRX1

    Graphical View of Domain Structure for InterPro Entry Q8TDN6

    ProtoNet protein and cluster: Q8TDN6

    1 Blocks protein family: IPB007109 Brix domain

    UniProtKB/Swiss-Prot: BRX1_HUMAN, Q8TDN6
    Similarity: Belongs to the BRX1 family
    Similarity: Contains 1 Brix domain


    Function
    for BRIX1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: BRX1_HUMAN, Q8TDN6
    Function: Required for biogenesis of the 60S ribosomal subunit

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BRIX1
    1 QIAGEN miScript miRNA Assays for microRNA that regulate BRIX1:
    hsa-miR-466
    SwitchGear 3'UTR luciferase reporter plasmid: BRIX1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BRIX1 (see all 4)
    OriGene shRNA RFP: BRIX1
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BRIX1

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for BRIX1

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BRIX1 (see all 3)
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    Sino Biological Human cDNA Clone for BRIX1
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BRIX1 

    Cell Line
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    Search LifeMap BioReagents cell lines for BRIX1

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BRIX1

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--


    BRIX1 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for BRIX1:
     Low eccentricity cells  Synthetic lethal with Ras 


    Pathways & Interactions
    for BRIX1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BRIX1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/751 Interacting proteins for BRIX1 (Q8TDN62, 3 ENSP000003388624) via UniProtKB, MINT, STRING, and/or I2D (see all 751)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0042254ribosome biogenesis IEA--


    BRIX1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for BRIX1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for BRIX1
    Search CenterWatch for drugs/clinical trials and news about BRIX1 / BRX1 

    Transcripts
    for BRIX1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for BRIX1 gene: 
    NM_018321.3  

    Unigene Cluster for BRIX1:

    BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
    Hs.718510  [show with all ESTs]
    Unigene Representative Sequence: BX648902
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000336767(uc003jja.3) ENST00000510960(uc011col.1) ENST00000515798
    ENST00000510834(uc003jiz.3) ENST00000506023

    miRNA
    Products:             		 OriGene 3'-UTR Clone: BRIX1
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BRIX1
    1 QIAGEN miScript miRNA Assays for microRNA that regulate BRIX1:
    hsa-miR-466
    SwitchGear 3'UTR luciferase reporter plasmid: BRIX1 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BRIX1 (see all 4)
    OriGene shRNA RFP: BRIX1
    OriGene siRNA: BRIX1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BRIX1
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BRIX1 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BRIX1 (see all 3)
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    GenScript: all cDNA clones in your preferred vector: BRIX1 (NM_018321)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BRIX1
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BRIX1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BRIX1

    Additional cDNA sequence: 

    AF347667.1 AK289610.1 AK303311.1 AK307492.1 AY364243.1 AY364244.1 BC001546.1 BC006014.1 
    BC036741.1 BX648902.1 

    12 DOTS entries:

    DT.100033743  DT.214328  DT.100724432  DT.92430524  DT.441509  DT.97843035  DT.444475  DT.92044223 
    DT.95375578  DT.97822164  DT.120802596  DT.309747 

    24/150 AceView cDNA sequences (see all 150):

    AW001647 AW271982 BX952902 AA418699 BI963051 AA058396 AA576507 AA730033 
    AK001962 BM553394 AW469852 AW272659 AA454607 CR622822 BE888528 BM764158 
    BM762111 AA418770 AA857813 BU167897 BC001546 AW469857 BG289827 AA505598 

    GeneLoc Exon Structure


    Expression
    for BRIX1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    BRIX1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ATCCCACTGC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    BRIX1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    LungLung BudLung
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See BRIX1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for BRIX1

    SOURCE GeneReport for Unigene cluster: Hs.718510
        SABiosciences Expression via Pathway-Focused PCR Array including BRIX1: 
              Embryonic Stem Cells in human mouse rat

    Primer
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BRIX1

    Orthologs
    for BRIX1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for BRIX1 gene from 10/34 species (see all 34)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Brix11 , 5 BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)1, 5 88.01(n)1
    91.78(a)1    		   15 (5.35 cM)5
    678321  NM_026396.31  NP_080672.31 
     104747795 
    chicken
    (Gallus gallus)    		 Aves BRIX11 BRX1, biogenesis of ribosomes, homolog (S. cerevisiae) 73.06(n)
    76.16(a)    		   427433  NM_001031449.1  NP_001026620.1 
    lizard
    (Anolis carolinensis)    		 Reptilia BRIX16
    		 --
    		 73(a)
    		 1 ↔ 1
    		 GL343241.1(2032471-2039813)
    African clawed frog
    (Xenopus laevis)    		 Amphibia AF319877.12   -- 77.19(n)    AF319877.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii Dr.97342 Danio rerio cDNA clone IMAGE6789379, partial cds 71.05(n)    BC056279.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG115831 CG11583 54.63(n)
    52.84(a)    		   326206  NM_001038900.1  NP_001033989.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea K12H4.31 Protein K12H4.3 54.18(n)
    45.94(a)    		   176134  NM_066355.4  NP_498756.1 
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes BRX1(YOL077C)4
    BRX11    		 Nucleolar protein, constituent of 66S pre-ribosomal more4
    Brx1p1    		 57.56(n)1
    50.6(a)1    		   15(186723-185848)4
    8540781, 4  NP_014565.21  NP_014565.14 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT1G529301 Ribosomal RNA processing Brix domain protein 52.6(n)
    48.44(a)    		   841726  NM_104171.2  NP_564618.1 
    rice
    (Oryza sativa)    		 Liliopsida Os02g05918001 hypothetical protein 53.65(n)
    49.83(a)    		   4329832  NM_001053824.1  NP_001047289.1 


    ENSEMBL Gene Tree for BRIX1 (if available)
    TreeFam Gene Tree for BRIX1 (if available) 

    Paralogs
    for BRIX1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for BRIX1 gene
    2 SIMAP similar genes for BRIX1 using alignment to 1 protein entry:     BRX1_HUMAN:
    BRIX    BXDC2

    BRIX1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for BRIX1
    PGOHUM00000249656


    Genomic Variants
    for BRIX1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/153 NCBI SNPs in BRIX1 are shown (see all 153)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 5 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs68610331,2
    		C,F,H,--34917846(+) TGCAGT/CTAATA 1 -- int128Minor allele frequency- C:0.04NS EA NA CSA WA 2668
    rs1391579121,2
    		--34917991(+) AGAGAC/TTGAAG 1 -- int10--------
    rs1915157371,2
    		--34918021(+) AGGAGA/GGCATT 1 -- int10--------
    rs1845955341,2
    		--34918145(+) GGTGCA/GGTGGT 1 -- int10--------
    rs1891153101,2
    		--34918280(+) CATGGC/TGGCAC 1 -- int10--------
    rs374341,2
    		C,F,H,--34918415(-) GATCTT/CGTTTT 1 -- int129Minor allele frequency- C:0.25NS EA NA WA 3068
    rs2022096881,2
    		--34918601(+) ATACTC/TTAGAA 1 -- int10--------
    rs2010845781,2
    		--34918606(+) TTAGAA/GATTTC 1 -- int10--------
    rs412706551,2
    		C,F,--34918654(-) GAATAT/CATAAA 1 -- int15Minor allele frequency- C:0.01NS WA 278
    rs1815739171,2
    		--34918660(+) TATTCC/TTCATT 1 -- int10--------

    HapMap Linkage Disequilibrium report for BRIX1 (34915481 - 34926101 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for BRIX1: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BRIX1
    DNA2.0 Custom Variant and Variant Library Synthesis for BRIX1

    Disorders / Diseases
    for BRIX1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    BRIX1 for disorders           About GeneDecksing

    2 diseases for BRIX1:    About MalaCards
    treacher collins syndrome    malaria


    Export disorders for BRIX1 gene to outside databases

    Publications
    for BRIX1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for BRIX1 gene, integrated from 9 sources (see all 25):
    (articles sorted by number of sources associating them with BRIX1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    4. Brix from Xenopus laevis and brx1p from yeast define a new family of proteins involved in the biogenesis of large ribosomal subunits. (PubMed id 11843177)1, 2 Kaser A.... Kreil G. (2001)
    5. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
    8. Interactome study suggests multiple cellular functions of hepatoma-derived growth factor (HDGF). (PubMed id 21907836)1 Zhao J....Yang P. (2011)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)

    External Searches for BRIX1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing BRIX1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55299 HGNC: 24170 AceView: BRIX Ensembl:ENSG00000113460 euGenes: HUgn55299
    ECgene: BRIX1 H-InvDB: BRIX1

    Other Databases showing BRIX1 gene

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    Specialized Databases showing BRIX1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for BRIX1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
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    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    		Patent Information for BRIX1 gene:
    Search GeneIP for patents involving BRIX1

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