Aliases for BRF2 Gene
External Ids for BRF2 Gene
Previous GeneCards Identifiers for BRF2 Gene
This gene encodes one of the multiple subunits of the RNA polymerase III transcription factor complex required for transcription of genes with promoter elements upstream of the initiation site. The product of this gene, a TFIIB-like factor, is directly recruited to the TATA-box of polymerase III small nuclear RNA gene promoters through its interaction with the TATA-binding protein. [provided by RefSeq, Jul 2008]
GeneCards Summary for BRF2 Gene
BRF2 (BRF2, RNA Polymerase III Transcription Initiation Factor 50 KDa Subunit) is a Protein Coding gene. Diseases associated with BRF2 include lung squamous cell carcinoma. Among its related pathways are Translational Control and Gene Expression.
UniProtKB/Swiss-Prot for BRF2 Gene
General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites.