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Aliases for BRF1 Gene

Aliases for BRF1 Gene

  • BRF1, RNA Polymerase III Transcription Initiation Factor Subunit 2 3 5
  • TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase III, GTF3B Subunit 2 2 3
  • BRF1, RNA Polymerase III Transcription Initiation Factor 90 KDa Subunit 2 3
  • TFIIIB90 3 4
  • TAF3B2 3 4
  • GTF3B 3 4
  • TAF3C 3 4
  • BRF-1 3 4
  • HBRF 3 4
  • BRF 3 4
  • BRF1 Homolog, Subunit Of RNA Polymerase III Transcription Initiation Factor IIIB (S. Cerevisiae) 2
  • BRF1 Homolog, Subunit Of RNA Polymerase III Transcription Initiation Factor IIIB 3
  • TATA Box-Binding Protein-Associated Factor, RNA Polymerase III, Subunit 2 4
  • TATA Box Binding Protein (TBP)-Associated Factor 3C 3
  • TBP - Associated Factor, RNA Polymerase III, 90kD 3
  • Epididymis Secretory Sperm Binding Protein Li 76p 3
  • General Transcription Factor IIIB, 90kD Subunit 3
  • Transcription Factor IIIB 90 KDa Subunit 3
  • B - Related Factor 1 3
  • B-Related Factor 1 4
  • HEL-S-76p 3
  • HTFIIIB90 4
  • TAFIII90 3
  • TF3B90 3
  • CFDS 3

External Ids for BRF1 Gene

Previous HGNC Symbols for BRF1 Gene

  • TAF3B2
  • TAF3C
  • GTF3B

Previous GeneCards Identifiers for BRF1 Gene

  • GC14M103054
  • GC14M099666
  • GC14M103647
  • GC14M104746
  • GC14M105675
  • GC14M085867

Summaries for BRF1 Gene

Entrez Gene Summary for BRF1 Gene

  • This gene encodes one of the three subunits of the RNA polymerase III transcription factor complex. This complex plays a central role in transcription initiation by RNA polymerase III on genes encoding tRNA, 5S rRNA, and other small structural RNAs. The gene product belongs to the TF2B family. Several alternatively spliced variants encoding different isoforms, that function at different promoters transcribed by RNA polymerase III, have been identified. [provided by RefSeq, Jun 2011]

GeneCards Summary for BRF1 Gene

BRF1 (BRF1, RNA Polymerase III Transcription Initiation Factor Subunit) is a Protein Coding gene. Diseases associated with BRF1 include Cerebellofaciodental Syndrome and Adult Syndrome. Among its related pathways are Transcription of tRNA and RNA Polymerase III Transcription Initiation. GO annotations related to this gene include TBP-class protein binding.

UniProtKB/Swiss-Prot for BRF1 Gene

  • General activator of RNA polymerase which utilizes different TFIIIB complexes at structurally distinct promoters. The isoform 1 is involved in the transcription of tRNA, adenovirus VA1, 7SL and 5S RNA. Isoform 2 is required for transcription of the U6 promoter.

Gene Wiki entry for BRF1 Gene

Additional gene information for BRF1 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BRF1 Gene

Genomics for BRF1 Gene

Regulatory Elements for BRF1 Gene

Enhancers for BRF1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14H104665 1.9 FANTOM5 Ensembl ENCODE dbSUPER 19.5 +649.1 649079 2.9 HDGF ZNF133 YBX1 DMAP1 ZBTB7B TCF12 ZNF302 ZNF207 FOS SP5 MTA1 XRCC3 ENSG00000257270 CDCA4 LINC00638 BRF1 ENSG00000270591 TMEM121 RPS20P33 CEP170B
GH14H105292 1.6 FANTOM5 Ensembl ENCODE dbSUPER 18.2 +21.8 21782 2.9 HDGF RFX1 SIN3A MAX BMI1 EBF1 ZIC2 POLR2A EED IKZF1 BRF1 BTBD6 TEDC1 GPR132 PACS2 GC14P105252
GH14H104966 1.9 FANTOM5 Ensembl ENCODE dbSUPER 10.7 +343.3 343320 11.9 HDGF PKNOX1 ZFP64 ARID4B SIN3A ZNF2 ZBTB7B ZNF207 ZNF143 FOS MTA1 CLBA1 AHNAK2 BRF1 CDCA4 LINC00638 ENSG00000257270 GPR132 IGHE CEP170B
GH14H105351 1.4 Ensembl ENCODE dbSUPER 12.2 -36.8 -36842 1.1 ELF3 ATF1 RB1 ARID4B RAD21 RFX5 GLIS2 ZNF143 ATF7 RUNX3 BRF1 PACS2 MTA1 ENSG00000279495
GH14H105470 1.3 ENCODE dbSUPER 10.8 -158.7 -158728 8 HDGF PKNOX1 ZFP64 ARID4B SIN3A ZNF2 ZBTB7B YY1 GLIS2 KLF7 MTA1 IGHVIII-11-1 HOMER2P2 IGHVII-33-1 HOMER2P1 IGHV3-42 ENSG00000271201 ENSG00000257270 BRF1 CLBA1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around BRF1 on UCSC Golden Path with GeneCards custom track

Promoters for BRF1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Locations for BRF1 Gene

Genomic Locations for BRF1 Gene
106,304 bases
Minus strand

Genomic View for BRF1 Gene

Genes around BRF1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BRF1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BRF1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BRF1 Gene

Proteins for BRF1 Gene

  • Protein details for BRF1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transcription factor IIIB 90 kDa subunit
    Protein Accession:
    Secondary Accessions:
    • B3KU36
    • B4DIG5
    • B7Z2N3
    • F5H5Z7
    • F8WA46
    • Q13223
    • Q3SYD9
    • Q5PR24
    • Q6IQ02
    • Q96KX3
    • Q9HCW6
    • Q9HCW7
    • Q9HCW8

    Protein attributes for BRF1 Gene

    677 amino acids
    Molecular mass:
    73840 Da
    Quaternary structure:
    • TFIIIB comprises at least the TATA-binding protein (TBP) and the B-related factor 1 (BRF1/TFIIIB90). Interacts with BDP1.
    • Sequence=AAC50170.1; Type=Frameshift; Positions=344, 405; Evidence={ECO:0000305};

    Alternative splice isoforms for BRF1 Gene

neXtProt entry for BRF1 Gene

Post-translational modifications for BRF1 Gene

  • Ubiquitination at Lys537
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for BRF1 Gene

Domains & Families for BRF1 Gene

Gene Families for BRF1 Gene

Human Protein Atlas (HPA):
  • Disease related genes
  • Predicted intracellular proteins
  • Predicted secreted proteins

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the TFIIB family.
  • Belongs to the TFIIB family.
genes like me logo Genes that share domains with BRF1: view

Function for BRF1 Gene

Molecular function for BRF1 Gene

GENATLAS Biochemistry:
butyrate response factor 1,member of the immediate early response gene family, specifying a putative nuclear transcription factor
UniProtKB/Swiss-Prot Function:
General activator of RNA polymerase which utilizes different TFIIIB complexes at structurally distinct promoters. The isoform 1 is involved in the transcription of tRNA, adenovirus VA1, 7SL and 5S RNA. Isoform 2 is required for transcription of the U6 promoter.

Phenotypes From GWAS Catalog for BRF1 Gene

Gene Ontology (GO) - Molecular Function for BRF1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001026 TFIIIB-type transcription factor activity IEA --
GO:0003743 translation initiation factor activity IEA --
GO:0017025 TBP-class protein binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with BRF1: view
genes like me logo Genes that share phenotypes with BRF1: view

Human Phenotype Ontology for BRF1 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

miRNA for BRF1 Gene

miRTarBase miRNAs that target BRF1

Clone Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for BRF1 Gene

Localization for BRF1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for BRF1 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for BRF1 gene
Compartment Confidence
nucleus 5
cytosol 2
extracellular 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear bodies (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for BRF1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000126 transcription factor TFIIIB complex NAS 8943358
GO:0005634 nucleus IEA --
GO:0005654 nucleoplasm TAS --
genes like me logo Genes that share ontologies with BRF1: view

Pathways & Interactions for BRF1 Gene

genes like me logo Genes that share pathways with BRF1: view

Interacting Proteins for BRF1 Gene

Selected Interacting proteins: Q92994-TF3B_HUMAN for BRF1 Gene via IID

Gene Ontology (GO) - Biological Process for BRF1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0006359 regulation of transcription from RNA polymerase III promoter IEA --
GO:0006383 transcription from RNA polymerase III promoter IEA,TAS 8943358
GO:0006384 transcription initiation from RNA polymerase III promoter TAS 7624363
genes like me logo Genes that share ontologies with BRF1: view

No data available for SIGNOR curated interactions for BRF1 Gene

Drugs & Compounds for BRF1 Gene

(1) Drugs for BRF1 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials

(2) Additional Compounds for BRF1 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with BRF1: view

Transcripts for BRF1 Gene

Unigene Clusters for BRF1 Gene

BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae):
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for BRF1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12a · 12b · 12c ^ 13a · 13b · 13c ^ 14 ^ 15a · 15b · 15c ·
SP1: - - - - - - - - -
SP2: - - - - - - - - - -
SP3: - - - - -
SP4: - -
SP5: - - - - - - - - -
SP6: - - - -
SP7: - - -
SP8: - - - -
SP9: - -
SP13: - - -
SP14: - -
SP15: - -

ExUns: 15d · 15e ^ 16 ^ 17a · 17b ^ 18 ^ 19 ^ 20 ^ 21 ^ 22
SP1: -
SP2: -
SP3: -
SP4: -
SP5: - - - - - - - - -
SP10: -

Relevant External Links for BRF1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for BRF1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for BRF1 Gene

Protein differential expression in normal tissues from HIPED for BRF1 Gene

This gene is overexpressed in Plasma (30.4), Heart (20.4), and Retina (6.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for BRF1 Gene

NURSA nuclear receptor signaling pathways regulating expression of BRF1 Gene:


SOURCE GeneReport for Unigene cluster for BRF1 Gene:


Evidence on tissue expression from TISSUES for BRF1 Gene

  • Nervous system(4.9)
  • Skin(4.4)
  • Liver(4.1)

Phenotype-based relationships between genes and organs from Gene ORGANizer for BRF1 Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
  • integumentary
  • nervous
  • respiratory
  • skeleton
Head and neck:
  • brain
  • cerebellum
  • ear
  • face
  • forehead
  • head
  • jaw
  • mandible
  • maxilla
  • mouth
  • neck
  • outer ear
  • skull
  • tooth
  • clavicle
  • lung
  • rib
  • rib cage
  • pelvis
  • arm
  • digit
  • femur
  • fibula
  • finger
  • forearm
  • hand
  • humerus
  • lower limb
  • radius
  • shin
  • thigh
  • tibia
  • ulna
  • upper limb
  • hair
  • skin
  • spinal column
  • vertebrae
genes like me logo Genes that share expression patterns with BRF1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for BRF1 Gene

Orthologs for BRF1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for BRF1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia BRF1 34
  • 100 (a)
(Canis familiaris)
Mammalia BRF1 33 34
  • 85.62 (n)
(Mus musculus)
Mammalia Brf1 33 16 34
  • 83.33 (n)
(Bos Taurus)
Mammalia BRF1 33 34
  • 82.81 (n)
(Rattus norvegicus)
Mammalia Brf1 33
  • 79.84 (n)
(Monodelphis domestica)
Mammalia BRF1 34
  • 79 (a)
(Ornithorhynchus anatinus)
Mammalia BRF1 34
  • 76 (a)
(Gallus gallus)
Aves BRF1 33 34
  • 72.12 (n)
(Anolis carolinensis)
Reptilia BRF1 34
  • 77 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia brf1 33
  • 69.55 (n)
(Danio rerio)
Actinopterygii brf1b 33 34
  • 66.52 (n)
wufi40c10 33
fruit fly
(Drosophila melanogaster)
Insecta Brf 35 33 34
  • 55.47 (n)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004233 33
  • 54.68 (n)
(Caenorhabditis elegans)
Secernentea brf-1 35 33 34
  • 45.85 (n)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AEL213W 33
  • 49.54 (n)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes BRF1 33 34 36
  • 48.06 (n)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0A05434g 33
  • 43.75 (n)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes brf1 33
  • 46.28 (n)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.6827 34
  • 46 (a)
Species where no ortholog for BRF1 was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for BRF1 Gene

Gene Tree for BRF1 (if available)
Gene Tree for BRF1 (if available)

Paralogs for BRF1 Gene

No data available for Paralogs for BRF1 Gene

Variants for BRF1 Gene

Sequence variations from dbSNP and Humsavar for BRF1 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs370270828 Pathogenic, Cerebellofaciodental syndrome (CFDS) [MIM:616202] 105,241,292(+) GCGCC(A/G)GCCTG intron-variant, reference, missense
rs371981699 A colorectal cancer sample 105,217,692(+) GAGCA(C/T)GCTAT reference, missense
rs373957300 Pathogenic, Cerebellofaciodental syndrome (CFDS) [MIM:616202] 105,228,832(+) GCAGC(A/G)TGGAC reference, missense
rs606231416 Pathogenic, Cerebellofaciodental syndrome (CFDS) [MIM:616202] 105,241,282(-) CCCCT(C/T)GGGCC intron-variant, reference, missense
rs606231450 Pathogenic, Cerebellofaciodental syndrome (CFDS) [MIM:616202] 105,226,674(-) CCCCC(A/C)CTCGT reference, missense

Structural Variations from Database of Genomic Variants (DGV) for BRF1 Gene

Variant ID Type Subtype PubMed ID
nsv952280 CNV deletion 24416366
nsv952279 CNV deletion 24416366
nsv9176 CNV gain+loss 18304495
nsv9175 CNV gain 18304495
nsv832890 CNV loss 17160897
nsv832889 CNV loss 17160897
nsv827085 CNV gain 20364138
nsv566198 CNV gain 21841781
nsv566195 CNV loss 21841781
nsv566190 CNV gain 21841781
nsv566189 CNV gain 21841781
nsv566188 CNV loss 21841781
nsv566187 CNV gain 21841781
nsv566186 CNV loss 21841781
nsv566185 CNV loss 21841781
nsv566150 CNV loss 21841781
nsv517055 CNV gain+loss 19592680
nsv511535 CNV gain 21212237
nsv510651 CNV deletion 20534489
nsv470679 CNV loss 18288195
nsv456458 CNV loss 19166990
nsv1439 CNV insertion 18451855
nsv1160204 CNV duplication 26073780
nsv1154053 CNV duplication 26484159
nsv1146619 CNV deletion 26484159
nsv1144716 CNV deletion 24896259
nsv1143763 CNV deletion 24896259
nsv1143762 CNV deletion 24896259
nsv1132387 CNV duplication 24896259
nsv1116759 CNV tandem duplication 24896259
nsv1115471 CNV duplication 24896259
nsv1113678 CNV deletion 24896259
nsv1112657 CNV deletion 24896259
nsv1075869 CNV duplication 25765185
nsv1070670 CNV deletion 25765185
nsv1070669 CNV deletion 25765185
nsv1070668 CNV deletion 25765185
nsv1070247 CNV deletion 25765185
nsv1054574 CNV loss 25217958
nsv1054190 CNV gain 25217958
nsv1052190 CNV gain 25217958
esv3635643 CNV gain 21293372
esv3635641 CNV gain 21293372
esv3635640 CNV gain 21293372
esv3635639 CNV gain 21293372
esv3635638 CNV loss 21293372
esv3552124 CNV deletion 23714750
esv3552121 CNV deletion 23714750
esv3449332 CNV duplication 20981092
esv3439820 CNV duplication 20981092
esv3337370 CNV duplication 20981092
esv3329450 CNV duplication 20981092
esv29986 CNV loss 17803354
esv2953 CNV loss 18987735
esv2760014 CNV loss 17122850
esv2749292 CNV deletion 23290073
esv2749291 CNV deletion 23290073
esv2749290 CNV deletion 23290073
esv2749288 CNV deletion 23290073
esv2749286 CNV deletion 23290073
esv2749284 CNV deletion 23290073
esv2749283 CNV deletion 23290073
esv2749282 CNV deletion 23290073
esv24753 CNV loss 19812545
esv22709 CNV gain+loss 19812545
esv2265156 CNV deletion 18987734
esv21762 CNV gain+loss 19812545
esv1410440 CNV deletion 17803354
esv1158096 CNV deletion 17803354
esv1010073 CNV gain 20482838
dgv3985n54 CNV gain+loss 21841781
dgv3984n54 CNV gain 21841781
dgv3983n54 CNV loss 21841781
dgv3977n54 CNV loss 21841781
dgv284e201 CNV deletion 23290073
dgv26n68 CNV loss 17160897
dgv267n27 CNV loss 19166990
dgv1339e59 CNV duplication 20981092
dgv1338e59 CNV duplication 20981092
dgv1337e59 CNV duplication 20981092

Variation tolerance for BRF1 Gene

Residual Variation Intolerance Score: 5.61% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.61; 31.04% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for BRF1 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BRF1 Gene

Disorders for BRF1 Gene

MalaCards: The human disease database

(4) MalaCards diseases for BRF1 Gene - From: HGMD, OMIM, ClinVar, Orphanet, Swiss-Prot, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
cerebellofaciodental syndrome
  • cerebellar-facial-dental syndrome
adult syndrome
  • acro-dermato-ungual-lacrimal-tooth syndrome
hemifacial microsomia
  • goldenhar syndrome
chronic rhinitis
  • rhinitis - chronic
- elite association - COSMIC cancer census association via MalaCards
Search BRF1 in MalaCards View complete list of genes associated with diseases


  • Cerebellofaciodental syndrome (CFDS) [MIM:616202]: An autosomal recessive disorder characterized by cerebellar hypoplasia, delayed development and intellectual disability, as well as facial dysmorphic features, short stature, microcephaly, and dental anomalies. {ECO:0000269 PubMed:25561519}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Relevant External Links for BRF1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with BRF1: view

No data available for Genatlas for BRF1 Gene

Publications for BRF1 Gene

  1. RNA polymerase III transcription from the human U6 and adenovirus type 2 VAI promoters has different requirements for human BRF, a subunit of human TFIIIB. (PMID: 8943358) Mital R … Hernandez N (Molecular and cellular biology 1996) 2 3 4 22 60
  2. Structure and function of a human transcription factor TFIIIB subunit that is evolutionarily conserved and contains both TFIIB- and high-mobility-group protein 2-related domains. (PMID: 7624363) Wang Z … Roeder RG (Proceedings of the National Academy of Sciences of the United States of America 1995) 2 3 4 60
  3. BRF1 mutations alter RNA polymerase III-dependent transcription and cause neurodevelopmental anomalies. (PMID: 25561519) Borck G … Kubisch C (Genome research 2015) 3 4 60
  4. New gene functions in megakaryopoiesis and platelet formation. (PMID: 22139419) Gieger C … Soranzo N (Nature 2011) 3 45 60
  5. Cellular senescence bypass screen identifies new putative tumor suppressor genes. (PMID: 17968325) Leal JF … Carnero A (Oncogene 2008) 3 22 60

Products for BRF1 Gene

Sources for BRF1 Gene

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