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Aliases for BREA2 Gene

Subcategory (RNA class) for BREA2 Gene

ncRNA

Quality Score for this RNA gene is

2

Aliases for BREA2 Gene

  • Breast Cancer Estrogen-Induced Apoptosis 2 3
  • AC105219.1 5

External Ids for BREA2 Gene

Previous GeneCards Identifiers for BREA2 Gene

  • GC08P144852
  • GC08P144779

Summaries for BREA2 Gene

GeneCards Summary for BREA2 Gene

BREA2 (Breast Cancer Estrogen-Induced Apoptosis 2) is an RNA Gene, and is affiliated with the ncRNA class.

Additional gene information for BREA2 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BREA2 Gene

Genomics for BREA2 Gene

Regulatory Elements for BREA2 Gene

Enhancers for BREA2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08H143289 1.4 ENCODE dbSUPER 19.7 -405.5 -405469 3 PKNOX1 MLX ARID4B SIN3A DMAP1 ZNF2 SLC30A9 ZNF766 CBX5 ZNF207 SHARPIN MINCR ZNF623 BREA2 MAF1 JRK TOP1MT ENSG00000254574 ENSG00000253728 ZFP41
GH08H144455 1.4 Ensembl ENCODE 19.6 +760.3 760293 1 HNRNPUL1 HDGF PKNOX1 FOXA2 ARNT ZFP64 SIN3A ZNF2 ZNF766 ZNF416 ZNF251 ZNF623 ZNF7 ZNF250 ZNF16 LRRC14 VPS28 CPSF1 ZNF517 ZNF34
GH08H143683 1 ENCODE 10.6 -11.4 -11412 1 PKNOX1 ATF1 ARID4B SIN3A DMAP1 ETS1 ELK1 ZNF207 ZNF143 ATF7 ZNF707 CPSF1 VPS28 ZNF623 ADCK5 SLC52A2 PARP10 GPAA1 BREA2 ZC3H3
GH08H143820 1.4 Ensembl ENCODE dbSUPER 4.6 +127.2 127182 5 FOXA2 ARID4B ZSCAN9 RAD21 RARA ZNF121 SCRT2 THAP11 EGR2 SP5 PUF60 BREA2 SCRIB
GH08H143468 0.8 ENCODE dbSUPER 5.7 -225.1 -225133 4 RING1 CTCF GLIS2 KLF1 GLIS1 JRK ZNF696 ZNF623 CYHR1 CPSF1 VPS28 GSDMD ENSG00000254859 ZC3H3 LOC105375798
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around BREA2 on UCSC Golden Path with GeneCards custom track

Genomic Location for BREA2 Gene

Chromosome:
8
Start:
143,696,154 bp from pter
End:
143,698,413 bp from pter
Size:
2,260 bases
Orientation:
Plus strand

Genomic View for BREA2 Gene

Genes around BREA2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BREA2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BREA2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BREA2 Gene

Proteins for BREA2 Gene

Post-translational modifications for BREA2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for BREA2 Gene

Domains & Families for BREA2 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for BREA2 Gene

Function for BREA2 Gene

Phenotypes for BREA2 Gene

GenomeRNAi human phenotypes for BREA2:
genes like me logo Genes that share phenotypes with BREA2: view

Animal Model Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for BREA2 Gene

Localization for BREA2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for BREA2 Gene

Pathways & Interactions for BREA2 Gene

SuperPathways for BREA2 Gene

No Data Available

Interacting Proteins for BREA2 Gene

Gene Ontology (GO) - Biological Process for BREA2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for BREA2 Gene

Drugs & Compounds for BREA2 Gene

No Compound Related Data Available

Transcripts for BREA2 Gene

mRNA/cDNA for BREA2 Gene

(1) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for BREA2 Gene

Breast cancer estrogen-induced apoptosis 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for BREA2 Gene

No ASD Table

Relevant External Links for BREA2 Gene

GeneLoc Exon Structure for
BREA2

Expression for BREA2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for BREA2 Gene

mRNA differential expression in normal tissues according to GTEx for BREA2 Gene

This gene is overexpressed in Testis (x8.7).

SOURCE GeneReport for Unigene cluster for BREA2 Gene:

Hs.178095
genes like me logo Genes that share expression patterns with BREA2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for BREA2 Gene

Orthologs for BREA2 Gene

Evolution for BREA2 Gene

ENSEMBL:
Gene Tree for BREA2 (if available)
TreeFam:
Gene Tree for BREA2 (if available)

No data available for Orthologs for BREA2 Gene

Paralogs for BREA2 Gene

No data available for Paralogs for BREA2 Gene

Variants for BREA2 Gene

Sequence variations from dbSNP and Humsavar for BREA2 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1001760585 -- 143,698,638(+) TCTTG(A/G)GAGCT downstream-variant-500B
rs1002041796 -- 143,697,425(+) GGGCT(A/G)CAGGC nc-transcript-variant
rs1004987274 -- 143,695,854(+) AGGCC(A/G)TGAGT intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1005318098 -- 143,698,463(+) GGGTC(C/T)GCCGT downstream-variant-500B
rs1005665695 -- 143,698,188(+) GTGGC(A/G)GATGC nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for BREA2 Gene

Variant ID Type Subtype PubMed ID
nsv466007 CNV loss 19166990
nsv519816 CNV loss 19592680
nsv612893 CNV loss 21841781

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Variation tolerance and Relevant External Links for BREA2 Gene

Disorders for BREA2 Gene

Relevant External Links for BREA2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
BREA2

No disorders were found for BREA2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BREA2 Gene

Publications for BREA2 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60

Products for BREA2 Gene

Sources for BREA2 Gene

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