BRE Gene
protein-coding GIFtS: 56
GCID: GC02P028025
|
|
brain and reproductive organ-expressed (TNFRSF1A modulator)
| |
Aliases
for BRE gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Brain And Reproductive Organ-Expressed (TNFRSF1A Modulator)1 2 | | BRCA1/BRCA2-Containing Complex Subunit 452 3 | | BRCC451 2 3 | | BRCA1-A Complex Subunit BRE2 | | BRCC41 2 | | BRCA1/BRCA2-Containing Complex, Subunit 42 | | Brain And Reproductive Organ-Expressed Protein2 3 | | |
Export aliases for BRE gene to outside databasesPrevious GC identifers: GC02P028034 GC02P028206 GC02P028088 GC02P027855 |
Summaries
for BRE gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: BRE_HUMAN, Q9NXR7Function: Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinatedhistones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage atdouble-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as an adapter that bridges theinteraction between BABAM1/NBA1 and the rest of the complex, thereby being required for the complex integrity andmodulating the E3 ubiquitin ligase activity of the BRCA1-BARD1 heterodimer. Probably also plays a role as a componentof the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin. May play a role inhomeostasis or cellular differentiation in cells of neural, epithelial and germline origins. May also act as a deathreceptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway. May regulate TNF-alphasignaling through its interactions with TNFRSF1A; however these effects may be indirect
Gene Wiki entry for BRE
|
Genomic Views
for BRE gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022184.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the BRE gene promoter:
Nkx2-5
Other transcription factors
Search SABiosciences Chromatin IP Primers for BRE
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BRE |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p23.2 Ensembl cytogenetic band: 2p23.2 HGNC cytogenetic band: 2p23BRE Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P028025: view genomic region
(about GC identifiers)
Start:
|
28,112,808 bp from pter |
End:
|
28,561,768 bp from pter |
Size:
|
448,961 bases |
Orientation:
|
plus strand |
|
Proteins
for BRE gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: BRE_HUMAN, Q9NXR7 (See
protein sequence)Recommended Name: BRCA1-A complex subunit BRE Size: 383 amino acids; 43552 Da
Subunit: Component of the BRCA1-A complex, at least composed of the BRCA1, BARD1, UIMC1/RAP80, FAM175A/Abraxas,BRCC3/BRCC36, BRE/BRCC45 and BABAM1/NBA1. In the BRCA1-A complex, interacts directly with FAM175A/Abraxas,BRCC3/BRCC36 and BABAM1/NBA1. Binds polyubiquitin. Component of the BRISC complex, at least composed of theFAM175B/ABRO1, BRCC3/BRCC36, BRE/BRCC45 and BABAM1/NBA1. Component of the BRCA1/BRCA2 containing complex (BRCC), whichalso contains BRCA1, BRCA2, BARD1, BRCC3/BRCC36 and RAD51. BRCC is a ubiquitin E3 ligase complex that enhancescellular survival following DNA damage. May interact with FAS and TNFRSF1A
Subcellular location: Cytoplasm. Nucleus. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs)
Secondary accessions: A8K4X1 D6W562 D6W563 Q13880 Q4ZFX8 Q53SD0 Q969X9 Q96P06Alternative splicing: 4 isoforms: Q9NXR7-2 Q9NXR7-1 Q9NXR7-3 Q9NXR7-4 Explore the universe of human proteins at neXtProt for BRE: NX_Q9NXR7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NXR7
BRE Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (6 alternative transcripts):
NP_001248769.1 NP_004890.2 NP_954661.1 NP_954662.1 NP_954663.1 NP_954664.1
ENSEMBL proteins: ENSP00000392345 ENSP00000343412 ENSP00000368945 ENSP00000339371 ENSP00000368953 ENSP00000354699 ENSP00000368950
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
BRE for ontologies About GeneDecksing
BRE Antibody Products:
Assay Products for BRE: |
Protein
Domains /
Families
for BRE gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
BRE for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9NXR7ProtoNet protein and cluster: Q9NXR7 UniProtKB/Swiss-Prot: BRE_HUMAN, Q9NXR7Domain: Contains 2 ubiquitin-conjugating enzyme family-like (UEV-like) regions. These regions lack the critical Cysresidues required for ubiquitination but retain the ability to bind ubiquitinSimilarity: Belongs to the BRE family |
Function
for BRE gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: BRE_HUMAN, Q9NXR7Function: Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinatedhistones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage atdouble-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as an adapter that bridges theinteraction between BABAM1/NBA1 and the rest of the complex, thereby being required for the complex integrity andmodulating the E3 ubiquitin ligase activity of the BRCA1-BARD1 heterodimer. Probably also plays a role as a componentof the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin. May play a role inhomeostasis or cellular differentiation in cells of neural, epithelial and germline origins. May also act as a deathreceptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway. May regulate TNF-alphasignaling through its interactions with TNFRSF1A; however these effects may be indirectInduction: Down-regulated by DNA-damaging agents in fibroblasts, by retinoic acid in brain glioma U-251MG andpromyelocytic HL-60 cell lines, and by bacterial lipopolysaccharides (LPS) in peripheral blood mononuclear cells(PBMC)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BRE (see all 11)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BRE (see all 6)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: BRE (NM_004961) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BRE | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BRE |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BRE |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
BRE for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for BRE:
Animal Models:
5 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Bre):
BRE for phenotypes About GeneDecksing
|
Pathways & Interactions
for BRE gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Apoptosis and survival_Caspase cascade | | | 2 | TWEAK Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 EMD Millipore Pathways for BRE
2  GeneGo (Thomson Reuters) Pathways for BRE
BRE for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for BRE
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/59 Interacting proteins for BRE (Q9NXR71, 2, 3 ENSP000003434124) via UniProtKB, MINT, STRING, and/or I2D (see all 59)About this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table
BRE for ontologies About GeneDecksing
|
Drugs & Compounds
for BRE gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for BRE
Search CenterWatch for drugs/clinical trials and news about BRE
|
Transcripts
for BRE gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for BRE gene (6 alternative transcripts): NM_001261840.1 NM_004899.4 NM_199191.2 NM_199192.2 NM_199193.2 NM_199194.2 Unigene Cluster for BRE: Brain and reproductive organ-expressed (TNFRSF1A modulator) Hs.258314 [show with all ESTs]Unigene Representative Sequence: NM_0048999 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000436924 ENST00000344773(uc002rlp.1 uc002rls.3 uc002rlu.3)
ENST00000379624(uc002rlv.3) ENST00000492702 ENST00000496951 ENST00000342045(uc002rlr.3)
ENST00000379632(uc002rlq.3) ENST00000361704(uc002rlt.3) ENST00000379629
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BRE (see all 11)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BRE (see all 6)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: BRE (NM_004961) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BRE | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BRE |
Additional cDNA sequence: AF015767.1 AF420602.1 AF420603.1 AF420604.1 AF420605.1 AK000097.1 AK098345.1 AK123076.1 AK291086.1 AY438031.1 BC001251.1 L38616.1 24/25 DOTS entries (see all 25): DT.101984934 DT.92446387 DT.95146598 DT.91702346 DT.86855482 DT.92446391 DT.100884657 DT.100884638 DT.100884642 DT.100884659 DT.454839 DT.95146595 DT.100884660 DT.92446385 DT.100884661 DT.121024320 DT.92446388 DT.121024326 DT.92446378 DT.121024164 DT.121024165 DT.121024210 DT.417608 DT.95146574 24/90 AceView cDNA sequences (see all 90): BC014088 BM717190 BE221723 AI452781 BQ016020 CD671167 AA860865 CR609030 AI912209 NM_022128 CA434266 AJ404857 BE501861 BE218181 H82519 BG201691 AA505744 AA393609 AL541410 BM833322 CD515982 AI266440 AI343781 BU621759
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for BRE (see all 7) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | · | 10c | ^ | 11a | · | 11b | ^ | 12a | · | 12b |
|---|
|
| SP1: | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for BRE
|
Expression
for BRE gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| BRE expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CGTGTCAGCA
About this image
See BRE Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for BRE
SOURCE GeneReport for Unigene cluster: Hs.258314
UniProtKB/Swiss-Prot: BRE_HUMAN, Q9NXR7Tissue specificity: Expressed in all cell lines examined. Highly expressed in placenta
SABiosciences Expression via Pathway-Focused PCR Arrays including BRE:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BRE
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat BRE | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BRE | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BRE | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BRE |
Orthologs
for BRE gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for BRE gene from 8/19 species (see all 19) About this table
ENSEMBL Gene Tree for BRE (if available)
TreeFam Gene Tree for BRE (if available) |
Paralogs
for BRE gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for BRE gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for BRE (28112808 - 28362808 bp, first 250kb of BRE)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 10 variations for BRE
5 CNVs: 3347 58978 50457 97797 7263
5 Indels: 45992 43054 40316 60290 12062 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BRE |
|
Disorders
/ Diseases
for BRE gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
BRE for disorders About GeneDecksing
OMIM gene information: 610497
OMIM disorders: --
9  diseases for BRE: About MalaCardsacute myeloid leukemia myeloid leukemia brain glioma esophageal carcinoma
hepatocellular carcinoma esophagitis leukemia ataxia
carcinoma
Human Genome Epidemiology (HuGE) Navigator: BRE (2 documents)
Export disorders for BRE gene to outside databases
|
Publications
for BRE gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for BRE gene, integrated from 9 sources (see all 49):
(articles sorted by number of sources associating them with BRE) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of a brain- and reproductive-organs-specific gene responsive to DNA damage and retinoic acid. (PubMed id 7826398)1, 2, 3 Li L.... Chan J.Y.-H. (1995)
- A death receptor-associated anti-apoptotic protein, BRE, inhibits mitochondrial apoptotic pathway. (PubMed id 15465831)1, 2, 9 Li Q.... Chui Y.-L. (2004)
- MERIT40 facilitates BRCA1 localization and DNA damage repair. (PubMed id 19261748)1, 2 Feng L.... Chen J. (2009)
- MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks. (PubMed id 19261746)1, 2 Shao G.... Greenberg R.A. (2009)
- NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control. (PubMed id 19261749)1, 2 Wang B.... Elledge S.J. (2009)
- K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC- associated Brcc36 and proteasomal Poh1. (PubMed id 19214193)1, 2 Cooper E.M....Cohen R.E. (2009)
- RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites. (PubMed id 17525341)1, 2 Sobhian B.... Greenberg R.A. (2007)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair. (PubMed id 14636569)1, 2 Dong Y.... Shiekhattar R. (2003)
|
External Searches for BRE gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing BRE gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing BRE gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing BRE gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for BRE gene:
Search GeneIP for patents involving BRE
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for BRE gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for BRE | | OriGene shRNA RFP for BRE | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BRE | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BRE | | | OriGene Protein Over-expression Lysate for BRE | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for BRE | | OriGene 3'-UTR Clone for BRE | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BRE | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BRE | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for BRE | | OriGene Custom Protein Services for BRE | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat BRE | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BRE | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BRE | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BRE | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BRE | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BRE |
| |
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| | | | Search Tocris compounds for BRE |
| |  |  |  |  | | | | |
 |
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 |
 | | | BRE Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BRE |
|  |  |  | | | | ThermoFisher Antibody for BRE |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BRE |
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