Aliases for BRD1 Gene
External Ids for BRD1 Gene
Previous GeneCards Identifiers for BRD1 Gene
This gene encodes a bromodomain-containing protein that localizes to the nucleus and can interact with DNA and histone tails. The encoded protein is a component of the MOZ/MORF acetyltransferase complex and can stimulate acetylation of histones H3 and H4, thereby potentially playing a role in gene activation. Variation in this gene is associated with schozophrenia and bipolar disorder in some study populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
GeneCards Summary for BRD1 Gene
BRD1 (Bromodomain Containing 1) is a Protein Coding gene. Among its related pathways are Chromatin organization and Regulation of TP53 Activity. GO annotations related to this gene include histone binding. An important paralog of this gene is BRPF3.
UniProtKB/Swiss-Prot for BRD1 Gene
Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
Bromodomains (BRDs) are epigenetic reader domains that selectively recognize acetylated lysine residues on the tails of histone proteins, and are the only known protein modules that can target acetylated lysine residues.