Aliases for BRD1 Gene
External Ids for BRD1 Gene
This gene encodes a bromodomain-containing protein that localizes to the nucleus and can interact with DNA and histone tails. The encoded protein is a component of the MOZ/MORF acetyltransferase complex and can stimulate acetylation of histones H3 and H4, thereby potentially playing a role in gene activation. Variation in this gene is associated with schozophrenia and bipolar disorder in some study populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
GeneCards Summary for BRD1 Gene
BRD1 (Bromodomain Containing 1) is a Protein Coding gene. Among its related pathways are RNA Polymerase I Promoter Opening and RNA Polymerase I Promoter Opening. GO annotations related to this gene include histone binding. An important paralog of this gene is PHF14.
UniProtKB/Swiss-Prot for BRD1 Gene
Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.