BPIFA3 Gene
protein-coding GIFtS: 37
GCID: GC20P031806
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BPI fold containing family A, member 3(Previous name: chromosome 20 open reading frame 71 )
(Previous symbol: C20orf71)
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Aliases
for BPIFA3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| BPI Fold Containing Family A, Member 31 2 | | BA49G10.41 | | C20orf711 2 3 | | Chromosome 20 Open Reading Frame 711 | | SPLUNC31 2 3 | | BPI Fold-Containing Family A Member 32 | | Short Palate, Lung And Nasal Epithelium Carcinoma-Associated Protein 32 3 | | Short Long Palate, Lung And Nasal Epithelium Carcinoma Associated 32 |
Export aliases for BPIFA3 gene to outside databases |
Summaries
for BPIFA3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for BPIFA3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011362.10
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for BPIFA3
Other transcription factors
Search SABiosciences Chromatin IP Primers for BPIFA3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BPIFA3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20q11.21 Ensembl cytogenetic band: 20q11.21 HGNC cytogenetic band: 20q11.21BPIFA3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20P031806: view genomic region
(about GC identifiers)
Start:
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31,805,116 bp from pter |
End:
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31,815,564 bp from pter |
Size:
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10,449 bases |
Orientation:
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plus strand |
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Proteins
for BPIFA3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: BPIA3_HUMAN, Q9BQP9 (See
protein sequence)Recommended Name: BPI fold-containing family A member 3 precursor Size: 254 amino acids; 28436 Da
Subcellular location: Secreted (Potential)
Secondary accessions: Q5JWG8 Q6NZ38Alternative splicing: 2 isoforms: Q9BQP9-1 Q9BQP9-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for BPIFA3: NX_Q9BQP9
BPIFA3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001035904.1 NP_848561.2
ENSEMBL proteins: ENSP00000364603 ENSP00000364601
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005576 | extracellular region |
IEA | -- |
BPIFA3 for ontologies About GeneDecksing
BPIFA3 Antibody Products:
Assay Products for BPIFA3: |
Protein
Domains /
Families
for BPIFA3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
BPIFA3 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9BQP9ProtoNet protein and cluster: Q9BQP9 UniProtKB/Swiss-Prot: BPIA3_HUMAN, Q9BQP9Similarity: Belongs to the BPI/LBP/Plunc superfamily. Plunc family |
Function
for BPIFA3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BPIFA3 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BPIFA3 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BPIFA3 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008289 | lipid binding |
IEA | -- |
BPIFA3 for ontologies About GeneDecksing
|
Pathways & Interactions
for BPIFA3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BPIFA3
|
Drugs & Compounds
for BPIFA3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for BPIFA3
Search CenterWatch for drugs/clinical trials and news about BPIFA3 / BPIA3
|
Transcripts
for BPIFA3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for BPIFA3 gene (2 alternative transcripts): NM_001042439.1 NM_178466.3 Unigene Cluster for BPIFA3: BPI fold containing family A, member 3 Hs.360989 [show with all ESTs]Unigene Representative Sequence: NM_1784664 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000490499 ENST00000471233 ENST00000375454(uc002wyr.3 uc002wys.3)
ENST00000375452
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BPIFA3 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BPIFA3 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for BPIFA3 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BPIFA3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BPIFA3 |
Additional cDNA sequence: BC066354.1 4 DOTS entries: DT.404854 DT.100745059 DT.120811241 DT.92433883 20 AceView cDNA sequences: AA912681 BC041904 AA971343 NM_178466 BC066354 AI017073 AW082233 BG717907 BX091954 AI638623 BI562604 AI073399 BI826928 AW082161 BF966133 AW072250 AA383555 BQ376632 AW340528 AL732092
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for BPIFA3 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 |
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| SP1: | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | | | - | | | | | | | | | | | | |
| SP3: | | | | | | | - | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for BPIFA3
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Expression
for BPIFA3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| BPIFA3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCAGGCTGGA
About this image
See BPIFA3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for BPIFA3
SOURCE GeneReport for Unigene cluster: Hs.360989
SABiosciences Custom PCR Arrays for BPIFA3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BPIFA3
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat BPIFA3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BPIFA3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BPIFA3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BPIFA3 |
Orthologs
for BPIFA3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for BPIFA3 (if available)
TreeFam Gene Tree for BPIFA3 (if available) |
Paralogs
for BPIFA3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for BPIFA3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for BPIFA3 (31805116 - 31815564 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for BPIFA3: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BPIFA3 |
|
Disorders
/ Diseases
for BPIFA3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
BPIFA3 for disorders About GeneDecksing
1  disease for BPIFA3: About MalaCardscarcinoma
Export disorders for BPIFA3 gene to outside databases
|
Publications
for BPIFA3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for BPIFA3 gene integrated from 9 sources:
(articles sorted by number of sources associating them with BPIFA3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily. (PubMed id 21787333)1, 3 Bingle C.D....Craven C.J. (2011)
- PLUNC: a novel family of candidate host defence proteins expressed in the upper airways and nasopharynx. (PubMed id 11971875)1, 3 Bingle C.D. and Craven C.J. (2002)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for BPIFA3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing BPIFA3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing BPIFA3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing BPIFA3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for BPIFA3 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for BPIFA3 gene:
Search GeneIP for patents involving BPIFA3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for BPIFA3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for BPIFA3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BPIFA3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BPIFA3 | | | OriGene Protein Over-expression Lysate for BPIFA3 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for BPIFA3 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BPIFA3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BPIFA3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for BPIFA3 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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 | | | BPIFA3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BPIFA3 |
|  |  |  | | | | Search ThermoFisher Antibodies for BPIFA3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BPIFA3 |
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