BPGM Gene
protein-coding GIFtS: 61
GCID: GC07P134331
|
|
2,3-bisphosphoglycerate mutase
| |
Aliases
for BPGM gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| 2,3-Bisphosphoglycerate Mutase1 2 | | Bisphosphoglycerate Mutase2 | | 2,3-Bisphosphoglycerate Mutase, Erythrocyte2 3 | | Erythrocyte 2,3-Bisphosphoglycerate Mutase2 | | 2,3-Bisphosphoglycerate Synthase2 3 | | EC 3.1.3.133 | | 2,3-Diphosphoglycerate Mutase2 3 | | EC 5.4.2.13 | | DPGM2 3 | | EC 5.4.2.43 | | BPG-Dependent PGAM2 3 | | |
Export aliases for BPGM gene to outside databasesPrevious GC identifers: GC07P132674 GC07P133733 GC07P133747 GC07P133788 GC07P133982 GC07P128633 |
Summaries
for BPGM gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for BPGM:
2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds toand decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPGsynthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also hasphosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen.Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein,have been identified. (provided by RefSeq, Sep 2009)
UniProtKB/Swiss-Prot: PMGE_HUMAN, P07738Function: Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allostericeffector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.1) and phosphatase (EC 3.1.3.13) activities
|
Genomic Views
for BPGM gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007933.15 NT_079596.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the BPGM gene promoter:
AML1a NRSF form 1 HNF-3beta NRSF form 2 C/EBPalpha YY1 AREB6 GATA-6 NF-Y CBF(2)
Other transcription factors
Search SABiosciences Chromatin IP Primers for BPGM
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BPGM |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q33 Ensembl cytogenetic band: 7q33 HGNC cytogenetic band: 7q33BPGM Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P134331: view genomic region
(about GC identifiers)
Start:
|
134,331,531 bp from pter |
End:
|
134,364,568 bp from pter |
Size:
|
33,038 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 133,675,849-133,708,886 |
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Proteins
for BPGM gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PMGE_HUMAN, P07738 (See
protein sequence)Recommended Name: Bisphosphoglycerate mutase Size: 259 amino acids; 30005 Da
Subunit: Homodimer
6/8 PDB 3D structures from  and Proteopedia  for BPGM (see all 8):1T8P (3D)
2A9J (3D)
2F90 (3D)
2H4X (3D)
2H4Z (3D)
2H52 (3D)
Secondary accessions: A4D1N9Explore the universe of human proteins at neXtProt for BPGM: NX_P07738
Post-translational modifications:
Glycation of Lys-159 in diabetic patients inactivates the enzyme1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P07738
BPGM Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001715.1 NP_954655.1
ENSEMBL proteins: ENSP00000342032 ENSP00000399838 ENSP00000376840 ENSP00000403050
Human Recombinant Protein Products:
BPGM Antibody Products:
Assay Products for BPGM: |
Protein
Domains /
Families
for BPGM gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
BPGM for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P07738ProtoNet protein and cluster: P07738 1 Blocks protein family: IPB001345 Phosphoglycerate/bisphosphoglycerate mutase
UniProtKB/Swiss-Prot: PMGE_HUMAN, P07738Similarity: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily |
Function
for BPGM gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: PMGE_HUMAN, P07738Function: Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allostericeffector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.1) and phosphatase (EC 3.1.3.13) activitiesCatalytic activity: 3-phospho-D-glyceroyl phosphate = 2,3-bisphospho-D-glycerateCatalytic activity: 2-phospho-D-glycerate = 3-phospho-D-glycerateCatalytic activity: 2,3-bisphospho-D-glycerate + H(2)O = 3-phospho-D-glycerate + phosphateEnzyme regulation: At alkaline pH BPGM favors the synthase reaction; however, at lower pH the phosphatase reaction isdominant. Inhibited by citrate Genatlas biochemistry entry for BPGM:2,3-bisphosphoglycerate mutase,glycolysis,energy pathway,Rapoport-Luebering shunt,major regulation ofbiphosphoglycerate concentration in erythrocyte
Enzyme Numbers (IUBMB): EC 5.4.2.41 EC 3.1.3.131 EC 5.4.2.11
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BPGM (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): BPGM (NM_199186) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BPGM | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BPGM |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BPGM |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004082 | bisphosphoglycerate mutase activity |
IEA | -- | | GO:0004083 | bisphosphoglycerate 2-phosphatase activity |
IEA | -- | | GO:0004619 | phosphoglycerate mutase activity |
IEA | -- | | GO:0016868 | intramolecular transferase activity, phosphotransferases |
-- | -- |
BPGM for ontologies About GeneDecksing
|
Pathways & Interactions
for BPGM gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Glycolysis and gluconeogenesis (short map) | | | 2 | gluconeogenesis I | | | 3 | Rapoport-Luebering glycolytic shunt | | | 4 | Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for BPGM
1  GeneGo (Thomson Reuters) Pathway for BPGM
3  BioSystems Pathways for BPGM
2 
Kegg Pathways (Kegg details for BPGM):
BPGM for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BPGM
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/29 Interacting proteins for BPGM (P077383 ENSP000003420324) via UniProtKB, MINT, STRING, and/or I2D (see all 29)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
BPGM for ontologies About GeneDecksing
|
Drugs & Compounds
for BPGM gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
BPGM for compounds About GeneDecksing
 Browse Tocris compounds for BPGM
4 HMDB Compounds for BPGM About this table
6 Novoseek chemical compound relationships for BPGM gene About this table
Search CenterWatch for drugs/clinical trials and news about BPGM / PMGE
|
Transcripts
for BPGM gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for BPGM gene (2 alternative transcripts): NM_001724.4 NM_199186.2 Unigene Cluster for BPGM: 2,3-bisphosphoglycerate mutase Hs.198365 [show with all ESTs]Unigene Representative Sequence: NM_1991864 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000344924(uc003vrw.3) ENST00000418040 ENST00000393132(uc003vrv.3)
ENST00000443095
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BPGM (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BPGM (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): BPGM (NM_199186) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BPGM | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BPGM |
Additional cDNA sequence: AB209044.1 AK097778.1 AK315439.1 BC017050.1 X04327.1 21 DOTS entries: DT.101977428 DT.315226 DT.100808810 DT.100808817 DT.75103877 DT.95289926 DT.100808820 DT.100808807 DT.100808813 DT.100835729 DT.40116900 DT.100766481 DT.100734968 DT.121061130 DT.92448520 DT.100662314 DT.100776864 DT.121060684 DT.40194658 DT.92448521 DT.95139112 24/338 AceView cDNA sequences (see all 338): CR626473 BM981935 AU102728 CR625693 BU663168 CR602739 BP343120 CB120317 BP371617 CR593475 NM_001724 CF265167 BU664976 BU664037 CN482687 AU137396 BX463043 CR598334 BP355075 BU157657 AI471846 BM977473 BC017050 CR590616
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for BPGM About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | · | 5d | ^ | 6a | · | 6b | ^ | 7 |
|---|
|
| SP1: | | | | | - | | - | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | - | | | | - | | | | | | | | | | | | | | | | |
| SP4: | | | | | - | | - | | - | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for BPGM
|
Expression
for BPGM gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| BPGM expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAAATAGCAG
About this image
See BPGM Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for BPGM
SOURCE GeneReport for Unigene cluster: Hs.198365
UniProtKB/Swiss-Prot: PMGE_HUMAN, P07738Tissue specificity: Expressed in red blood cells. Expressed in non-erythroid cells of the placenta; present in thesyncytiotrophoblast layer of the placental villi at the feto-maternal interface (at protein level)
SABiosciences Expression via Pathway-Focused PCR Array including BPGM:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BPGM
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat BPGM | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BPGM | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BPGM | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BPGM |
Orthologs
for BPGM gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for BPGM gene from 8/29 species (see all 29) About this table
ENSEMBL Gene Tree for BPGM (if available)
TreeFam Gene Tree for BPGM (if available) |
Paralogs
for BPGM gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for BPGM gene
- PGAM12 PGAM22 PGAM42
3 SIMAP similar genes for BPGM using alignment to 2 protein entries: PMGE_HUMAN (see all proteins):PGAM1 PGAM4 PGAM2
BPGM for paralogs About GeneDecksing
|
Genomic Variants
for BPGM gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for BPGM (134331531 - 134364568 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for BPGM
1 CNV: 100129
4 Indels: 42962 12966 47239 62727
Human Gene Mutation Database (HGMD): BPGM
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BPGM |
|
Disorders
/ Diseases
for BPGM gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
BPGM for disorders About GeneDecksing
OMIM gene information: 613896
OMIM disorders: --
UniProtKB/Swiss-Prot: PMGE_HUMAN, P07738
Defects in BPGM are the cause of bisphosphoglycerate mutase deficiency (BPGMD) [MIM:222800]. A diseasecharacterized by hemolytic anemia, splenomegaly, cholelithiasis and cholecystitis
13  diseases for BPGM: About MalaCardshemolytic anemia glycogen storage disease v anemia glycogen storage disease
sickle cell anemia erythrocytosis splenomegaly cholecystitis
cholelithiasis pneumonia tuberculosis malaria
mycobacterium tuberculosis
Genatlas disease: BPGM erythrocytosis
Export disorders for BPGM gene to outside databases
|
Publications
for BPGM gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for BPGM gene, integrated from 9 sources (see all 49):
(articles sorted by number of sources associating them with BPGM) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Structural modeling of the human erythrocyte bisphosphoglycerate mutase. (PubMed id 1387804)1, 2, 9 Craescu C.T.... Edelstein S.J. (1992)
- Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase. (PubMed id 17052986)1, 2, 9 Wang Y....Gong W. (2006)
- Human erythrocyte bisphosphoglycerate mutase: inactivation by glycation in vivo and in vitro. (PubMed id 9832630)1, 2, 9 Fujita T.... Taniguchi N. (1998)
- Unliganded structure of human bisphosphoglycerate mut ase reveals side-chain movements induced by ligand binding. (PubMed id 21045285)1, 2 Patterson A....Nairn J. (2010)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
- The platelet-activating factor acetylhydrolase from human erythrocytes. Purification and properties. (PubMed id 8440681)1, 2 Stafforini D.M.... McIntyre T.M. (1993)
- Isolation, characterization, and structure of a mutant 89 Arg----Cys bisphosphoglycerate mutase. Implication of the active site in the mutation. (PubMed id 2542247)1, 2 Rosa R....Rosa J. (1989)
- Isolation and characterization of the human 2,3-bisphosphoglycerate mutase gene. (PubMed id 2844822)1, 2 Joulin V....Cohen-Solal M. (1988)
|
External Searches for BPGM gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing BPGM gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing BPGM gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing BPGM gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for BPGM | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for BPGM gene:
Search GeneIP for patents involving BPGM
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for BPGM gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for BPGM | | OriGene shRNA RFP for BPGM | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BPGM | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BPGM | | | OriGene Protein Over-expression Lysate for BPGM | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for BPGM | | OriGene 3'-UTR Clone for BPGM | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BPGM | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BPGM | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for BPGM | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat BPGM | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BPGM | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BPGM | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BPGM | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BPGM | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BPGM |
| |
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| | | | Search Tocris compounds for BPGM |
| |  |  |  |  | | | | | | Recombinant Protein for BPGM |
|
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 | | | BPGM Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BPGM |
|  |  |  | | | | ThermoFisher Antibodies for BPGM |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BPGM |
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