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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

BOP1 Gene

protein-coding   GIFtS: 54
GCID: GC08M145486

Block Of Proliferation 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Block Of Proliferation 11 2
Block Of Proliferation 1 Protein2 3
KIAA01243 5
Ribosome Biogenesis Protein BOP12

External Ids:    HGNC: 155191   Entrez Gene: 232462   Ensembl: ENSG000001707277   OMIM: 6105965   UniProtKB: Q141373   

Export aliases for BOP1 gene to outside databases

Previous GC identifers: GC08M143100 GC08M145571 GC08M145090 GC08M145422 GC08M145490 GC08M145456 GC08M140600


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for BOP1 Gene: 
BOP1 (block of proliferation 1) is a protein-coding gene. Diseases associated with BOP1 include pancreatic cancer, and hepatocellular carcinoma. GO annotations related to this gene include protein binding. An important paralog of this gene is LOC727967.

UniProtKB/Swiss-Prot: BOP1_HUMAN, Q14137
Function: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and
formation of the 60S ribosome

Gene Wiki entry for BOP1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NC_018919.2  NT_037704.5  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the BOP1 gene promoter:
         AP-2alpha isoform 3   AP-2alpha isoform 2   AP-2alpha isoform 4   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBOP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for BOP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BOP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q24.3   Ensembl cytogenetic band:  8q24.3   HGNC cytogenetic band: 8q24.3

BOP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BOP1 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M145486:  view genomic region     (about GC identifiers)

Start:
145,486,055 bp from pter      End:
145,515,120 bp from pter
Size:
29,066 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: BOP1_HUMAN, Q14137 (See protein sequence)
Recommended Name: Ribosome biogenesis protein BOP1  
Size: 746 amino acids; 83630 Da
Subunit: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts
directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome
Subcellular location: Nucleus, nucleolus. Nucleus, nucleoplasm
Secondary accessions: Q969Z6 Q96IS8 Q9BSA7 Q9BVM0

Explore the universe of human proteins at neXtProt for BOP1: NX_Q14137

Explore proteomics data for BOP1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q14137

  • BOP1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    BOP1 Protein Expression
    REFSEQ proteins: NP_056016.1  
    ENSEMBL proteins: 
     ENSP00000304151   ENSP00000432017   ENSP00000435997   ENSP00000436398  

    Human Recombinant Protein Products for BOP1: 
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    Novus Biologicals BOP1 Protein
    Novus Biologicals BOP1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for BOP1 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0005654nucleoplasm IEA--
    GO:0030529ribonucleoprotein complex IDA18809582
    GO:0070545PeBoW complex IDA16043514

    BOP1 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. ELISAs for BOP1 
    Cloud-Clone Corp. CLIAs for BOP1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    WDR: WD repeat domain containing

    5 InterPro protein domains:
     IPR019775 WD40_repeat_CS
     IPR001680 WD40_repeat
     IPR012953 BOP1_N_dom
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q14137

    ProtoNet protein and cluster: Q14137

    1 Blocks protein domain: IPB012953 BOP1

    UniProtKB/Swiss-Prot: BOP1_HUMAN, Q14137
    Similarity: Belongs to the WD repeat BOP1/ERB1 family
    Similarity: Contains 7 WD repeats


    BOP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BOP1_HUMAN, Q14137
    Function: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and
    formation of the 60S ribosome
    Induction: By MYC

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16043514
         
    BOP1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for BOP1:
     Decreased viability  Wnt reporter downregulated 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for BOP1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for BOP1

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    miRNA
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    Inhib. RNA
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    Clone
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BOP1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for BOP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/177 Interacting proteins for BOP1 (Q141371, 2, 3 ENSP000003041514) via UniProtKB, MINT, STRING, and/or I2D (see all 177)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000463maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP17353269
    GO:0006364rRNA processing ----
    GO:0008283cell proliferation NAS16043514
    GO:0042254ribosome biogenesis NAS16043514
    GO:0051726regulation of cell cycle IMP16043514

    BOP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for BOP1

    Search CenterWatch for drugs/clinical trials and news about BOP1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for BOP1 gene: 
    NM_015201.3  

    Unigene Cluster for BOP1:

    Block of proliferation 1
    Hs.645279  [show with all ESTs]
    Unigene Representative Sequence: NM_015201
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000307404(uc003zbr.1) ENST00000526471 ENST00000529245 ENST00000526552
    ENST00000530355 ENST00000525016 ENST00000529231 ENST00000524861 ENST00000533125

    miRNA
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    Inhib. RNA
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    Browse for Gene Knock-down Tools from EMD Millipore
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BOP1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BOP1

    Additional mRNA sequence: 

    AB060694.1 AK024840.1 AK290677.1 AK293719.1 AK310015.1 AK315612.1 BC001086.2 BC005160.2 
    BC007274.1 BC013787.1 BC013980.2 BC017674.2 BC073813.1 BC098446.1 D50914.1 

    8 DOTS entries:

    DT.100790510  DT.100790506  DT.100790500  DT.112989  DT.95163462  DT.92453052  DT.95163456  DT.95163458 

    24/383 AceView cDNA sequences (see all 383):

    BQ642571 BQ678643 BC013980 BQ433386 BG282993 BC017674 BQ061984 BG256906 
    BQ438001 BU157993 CD370768 BG756399 BU189114 CA417767 BG392051 BM705157 
    AI360404 CA309887 BQ083044 NM_015201 D50914 BQ649889 BQ680728 BX400424 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for BOP1    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15
    SP1:                                                                                                                  
    SP2:                                                                                                                  
    SP3:                                                                                                                  
    SP4:                                                        -                                                         
    SP5:                                                                                                                  


    ECgene alternative splicing isoforms for BOP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    BOP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGTACAATG
    BOP1 Expression
    About this image


    See BOP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for BOP1

    SOURCE GeneReport for Unigene cluster: Hs.645279
        SABiosciences Custom PCR Arrays for BOP1
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for BOP1 gene from 10/23 species (see all 23)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Bop11 , 5 block of proliferation 11, 5 81.97(n)1
    84.7(a)1
      15 (35.91 cM)5
    121811  NM_013481.11  NP_038509.11 
     764529965 
    chicken
    (Gallus gallus)
    Aves BOP11 block of proliferation 1 77.16(n)
    76.3(a)
      425985  XM_423665.3  XP_423665.3 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    78(a)
    1 → many
    AAWZ02039979(21-6726)
    African clawed frog
    (Xenopus laevis)
    Amphibia bop1-prov2 block of proliferation 1 78.55(n)    BC044074.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc64d062 wufc64d06 75.51(n)   325279  BG985514.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta EG:52C10.13
    CG50331
    transcription factor3
    CG50331
    53(a)3
    57.9(n)1
    51.86(a)1
      54E93
    370361  NM_137426.31  NP_611270.11 
    worm
    (Caenorhabditis elegans)
    Secernentea Y48B6A.13
    CELE_Y48B6A.11
    Protein Y48B6A.11 46(a)3
    54.28(n)1
    48.3(a)1
      II(14151241-14154259)3
    1750691  NM_064555.31  NP_496956.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ERB1(YMR049C)4
    ERB11
    Constituent of 66S pre-ribosomal particles, forms a more4
    Erb1p1
    44.95(n)1
    41.77(a)1
      13(370517-368094)4
    8550681, 4  NP_013764.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G403601 transducin/WD-40 repeat-containing protein 47.84(n)
    42.79(a)
      818629  NM_129596.3  NP_181567.3 
    rice
    (Oryza sativa)
    Liliopsida Os07g04354001 hypothetical protein 49.07(n)
    44.78(a)
      4343071  NM_001066037.1  NP_001059502.1 


    ENSEMBL Gene Tree for BOP1 (if available)
    TreeFam Gene Tree for BOP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for BOP1 gene
    LOC7279672  
    1 SIMAP similar gene for BOP1 using alignment to 6 protein entries:     BOP1_HUMAN (see all proteins):
    KM-PA-2

    BOP1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/356 SNPs in BOP1 are shown (see all 356)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs70168571,2
    A--140600981(+) GACGCA/GAAGAG 3 L F mis1 ese30--------
    rs1159884331,2
    C--145494298(+) AGAGAC/TGTCAG 1 -- int10--------
    rs1468859631,2
    --145494835(+) AGGGG-/CCCCCA 1 -- int10--------
    rs1160540661,2
    C--145494850(+) GCACCC/TTGGGC 1 -- int10--------
    rs1481381401,2
    C--145495068(+) GAGCC-/CCGG  
            
    CCGGC
    1 -- int10--------
    rs1147444211,2
    C--145495223(+) GCCCCC/TTTCCC 1 -- int10--------
    rs1162953261,2
    C--145495578(+) TCTGTC/TGAAGT 1 -- int10--------
    rs1159831151,2
    C--145495662(+) GGCCCC/TGGCGC 1 -- int10--------
    rs1387011431,2
    C--145497364(+) CCCAG-/ACT   
       CCAGA
    CCCCA
    1 -- int10--------
    rs1151744071,2
    C--145497378(+) TCCAGA/GCCCCA 1 -- int10--------

    HapMap Linkage Disequilibrium report for BOP1 (145486055 - 145515120 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/34 variations for BOP1 (see all 34):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2253218CNV Deletion18987734
    esv2738055CNV Deletion23290073
    esv989584CNV Deletion20482838
    esv2675243CNV Deletion23128226
    esv2738060CNV Deletion23290073
    esv2738061CNV Deletion23290073
    esv2738059CNV Deletion23290073
    esv3547CNV Deletion18987735
    esv2738057CNV Deletion23290073
    esv2738058CNV Deletion23290073

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610596    OMIM disorders: --

    4 diseases for BOP1:    About MalaCards
    pancreatic cancer    hepatocellular carcinoma    colon cancer    pancreatitis


    BOP1 for disorders           About GeneDecksing


    Export disorders for BOP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for BOP1 gene, integrated from 9 sources (see all 37):
    (articles sorted by number of sources associating them with BOP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8590280)1, 2, 3 Nagase T....Nomura N. (1995)
    2. Interdependence of Pes1, Bop1, and WDR12 controls nucleolar localization and assembly of the PeBoW complex required for maturation of the 60S ribosomal subunit. (PubMed id 17353269)1, 2 Rohrmoser M.... Eick D. (2007)
    3. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
    4. Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex. (PubMed id 16738141)1, 2 Grimm T....Eick D. (2006)
    5. Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation. (PubMed id 16043514)1, 2 Holzel M....Eick D. (2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (2002)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    9. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    10. Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23246 HGNC: 15519 AceView: BOP1 Ensembl:ENSG00000170727 euGenes: HUgn23246
    ECgene: BOP1 H-InvDB: BOP1

    (According to HUGE)
    About This Section
    HUGE: KIAA0124

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for BOP1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for BOP1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for BOP1 gene:
    Search GeneIP for patents involving BOP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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