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BOLL Gene

protein-coding GIFtS: 54

GC02M198299

bol, boule-like (Drosophila)
(Previous name: bol (Drosophila boule homolog)-like )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
BOULE ^¹, ³
boule ^²

Descriptions
bol (Drosophila boule homolog)-like ^¹
bol, boule-like (Drosophila) ^²

External Ids
HGNC: 14273¹
Entrez Gene: 66037²
UniProtKB: Q8N9W6³
Ensembl: ENSG00000152430⁷

Search outside databases for aliases for BOLL gene

Previous GC identifers: GC02M196791 GC02M197304 GC02M198555 GC02M198794 GC02M198417

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for BOLL:

This gene belongs to the DAZ gene family required for germ cell development. It encodes an

RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by

genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene

function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated

that the primary defect is at the meiotic G2/M transition. Two alternatively spliced transcript

variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]

UniProtKB/Swiss-Prot: BOLL_HUMAN, Q8N9W6

Function: Probable RNA-binding protein, which may be required during spermatogenesis. May act by

binding to the 3'-UTR of mRNAs and regulating their translation (By similarity)

Gene Wiki entry for BOLL

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the BOLL gene

Entrez Gene cytogenetic band: 2q33 Ensembl cytogenetic band: 2q33.1 HGNC cytogenetic band: 2q33

BOLL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02M198299: (about GC identifiers)

Start:	198,299,856 bp from pter
End:	198,359,183 bp from pter
Size:	59,328 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000002.10 NT_005403.16

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: BOLL_HUMAN, Q8N9W6 (See protein sequence)

Recommended Name: Protein boule-like

Size: 283 amino acids; 31301 Da

Subunit: Interacts with DAZ1 and DAZL

Subcellular location: Cytoplasm

Secondary accessions: Q0JW32 Q53T62 Q969U3

Alternative splicing: 4 isoforms: Q8N9W6-1 Q8N9W6-2 Q8N9W6-3 Q8N9W6-4

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_149019.1 NP_932074.1

ENSEMBL proteins:

ENSP00000376117 ENSP00000314792 ENSP00000282278 ENSP00000376116

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (BOULE)
	Human Recombinant Proteins from Abnova (BOLL)

OriGene Purified Recombinant Human Protein: BOLL

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IDA	11390979

About this table

Antibodies for BOLL:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for BOLL
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (BOULE), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (BOLL)
	Novus Biologicals Antibodies for BOLL

Assays for BOLL:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q8N9W6

ProtoNet protein and cluster: Q8N9W6

1 Blocks protein family: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)

UniProtKB/Swiss-Prot: BOLL_HUMAN, Q8N9W6

Similarity: Belongs to the RRM DAZ family

Similarity: Contains 1 DAZ-like domain

Similarity: Contains 1 RRM (RNA recognition motif) domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (BOLL)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (BOLL)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_033030

Applied Biosystems Silencer® siRNAs for BOLL

Sigma-Aldrich siRNA and siRNA Panels for BOLL

Sigma-Aldrich shRNA for BOLL

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for BOLL
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_033030
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_033030
untagged cDNA clones in CMV expression vector (see all 2): NM_033030

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_197970

UniProtKB/Swiss-Prot: BOLL_HUMAN, Q8N9W6

Function: Probable RNA-binding protein, which may be required during spermatogenesis. May act by

binding to the 3'-UTR of mRNAs and regulating their translation (By similarity)

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0003723	RNA binding	IEA	--
GO:0005515	protein binding	IPI	16001084
GO:0008494	translation activator activity	IDA	16001084

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Interacting protein for BOLL (Q8N9W6¹) via UniProtKB, MINT, and/or STRING
Interactant Interaction Details
GeneCard External ID(s)
DAZ1 Q9NQZ3¹ EBI-998198, EBI-997955
About this table
5/6 Gene Ontology (GO) biological process terms (links to tree view) (see all 6 ):
GO ID Qualified GO term Evidence PubMed IDs
GO:0006417 regulation of translation IEA --
GO:0007126 meiosis IDA 12499397
GO:0007275 multicellular organismal development IEA --
GO:0007283 spermatogenesis IEA --
GO:0030154 cell differentiation IEA --
About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for BOLL

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (BOLL)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (BOLL)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_033030

Sigma-Aldrich siRNA and siRNA Panels for BOLL

Sigma-Aldrich shRNA for BOLL

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_033030 NM_197970

REFSEQ mRNAs for BOLL gene (2 alternative transcripts):

NM_033030.5 NM_197970.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_033030 NM_197970

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_033030
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_033030
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_033030

Additional cDNA sequence:

AF272858.1 AK058099.1 AK093453.1 AK097795.1 AK098824.1 AK302817.1 AM295005.1 BC033674.1

3 DOTS entries:

DT.92068142 DT.99930769 DT.99927331

24/49 AceView cDNA sequences (see all 49 ):

BP368992 BC033674 AK093453 AK097795 AK058099 BF059752 NM_033030 AX748137

NM_197970 AK098824 AA954512 BI460610 BG723959 BM563752 AI797395 AF272858

AI381516 AW182097 BG722029 BI561445 BG772456 AA983861 AI424966 BQ438372

highest scoring ESTs for BOLL:

AI424966 AK097795 AA401472 AI190319 AI381516 AK058099 AK093453 AK098824 AW770088 BC033674

Unigene Cluster for BOLL:

Bol, boule-like (Drosophila)

Hs.169797 [show with all ESTs]

Unigene Representative Sequence: NM_033030

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for BOLL

ExUns:	1	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12	^	13	^	14a	·	14b
SP1:
SP2:			-		-														-
SP3:					-														-

About this scheme

ECgene alternative splicing isoforms for BOLL

4 Ensembl transcripts including schematic representations:

ENST00000392297 ENST00000321801 ENST00000282278 ENST00000392296

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

BOLL expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for BOLL

¹ / ² / ³

5 probe-sets matching BOLL gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
85138_at²^{, 3}	U95-D	1	1.00	1.00	0.83	1.51	AI190319	0.60	1.00	0.82	1
47260_at²^{, 3}	U95-B	1	1.00	1.00	0.91	0.42	AI424966	0.80	1.00	0.91	1
83763_at²^{, 3}	U95-D	1	1.00	1.00	0.61	1.49	AI381516	0.60	1.00	0.82	1
236954_at²^{, 3}	U133-B	1	1.00	1.00	--	--	BF059752	0.60	1.00	0.82	1
236954_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks BOLL for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.169797
UniProtKB/Swiss-Prot: BOLL_HUMAN, Q8N9W6
Tissue specificity: Testis specific. Not expressed in early embryos, primoridal germ cells and
spermatogonial cells. First expressed in the cytoplasm of spermatocytes and then persists through
meiosis

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for BOLL gene from 5/8 species (see all 8 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	BOLL¹	--	bol, boule-like (Drosophila)	94.9(n) 93.88(a)	488458 XM_545580.2 XP_545580.2
chimpanzee (Pan troglodytes)	BOLL¹	--	bol, boule-like (Drosophila)	99.65(n) 99.65(a)	459855 XM_001169413.1 XP_001169413.1
cow (Bos taurus)	BOLL¹	--	bol, boule-like (Drosophila)	94.1(n) 94.79(a)	527841 XM_606246.3 XP_606246.3
rat (Rattus norvegicus)	Boll¹	--	bol, boule-like (Drosophila)	90.24(n) 90.94(a)	501143 XM_576567.2 XP_576567.2
mouse (Mus musculus)	Boll^{1, 5}	1⁵	bol, boule-like (Drosophila)^{1, 5}	93.08(n)¹ 93.85(a)¹	75388¹ NM_029267.2¹ NP_083543.1¹ AF272859⁵ AK016125⁵ (see all 9)

About this table Species with no ortholog for BOLL

ENSEMBL Gene Tree for BOLL

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for BOLL gene

DAZL² DAZ1² DAZ3² DAZ4² DAZ2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/157 NCBI SNPs in BOLL are shown (see all 157 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 39)

AB	SNP ID	Valid	Chr 2 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs771018^1,2	A,C	198358504(-)	`AGGACC/TGGAAG`	2	--	int¹ ng3¹		0	--	--	--	--
	rs2272166^1,2	H	198299929(-)	`TTTTGA/GTTTTC`	2	--	ut3¹		4		EU EA WA	418
	rs13015235^1,2	H	198359580(+)	`ACTCTC/GGGGGC`	2	--	ng3¹		4		EU EA WA	418
--	rs13396873^1,2	H	198299533(+)	`gagccA/Ctgatc`	2	--	ng5¹		4		EU EA WA	420
	rs700654^1,2	A,C,F,H,O	198351666(-)	`AGTAGC/TAGATG`	2	--	int¹		8		EA NA EU WA	568
	rs2293255^1,2	A,C,F,H,O	198329751(-)	`CATTAA/GGAAGT`	2	--	int¹		8		EA EU WA NA	2038
	rs700650^1,2	A,C,F,H	198332530(+)	`actggA/Ggttcc`	2	--	int¹		8		EU EA WA NA	636
	rs700653^1,2	A,C,F,H	198345678(+)	`AATATA/GCATAG`	2	--	int¹		4		EU EA WA	418
	rs700643^1,2	A,C,F,H	198309615(-)	`CCAAAC/TGTCCT`	2	--	int¹		4		EU EA WA	416
--	rs700646^1,2	A,C,F,H	198316756(-)	`tgtttA/Gtattg`	2	--	int¹		4		EU EA WA	418

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HapMap Linkage Disequilibrium images for BOLL (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 606165

4 Novoseek disease relationships for BOLL gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
azoospermia	88.04	9	8657280 (1), 12499397 (1), 18550751 (1), 9486791 (1) (see all 9)
infertility male	77.40	5	10819768 (1), 9294855 (1), 9321470 (1), 10857750 (1) (see all 5)
sterility male	61.66	1	9486791 (1)
oligozoospermia	59.39	1	8968756 (1)

About this table

Genetic Association Database: BOLL
Human Genome Epidemiology Navigator: BOLL (4 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/32 PubMed articles for BOLL gene (see all 32 ):

A gene family required for human germ cell development evolved from an ancient meiotic gene conserved in metazoans. (PubMed id 11390979)^{2, 3, 4} Xu E.Y.... Reijo Pera R.A. (2001)
Association of three isoforms of the meiotic BOULE gene with spermatogenic failure in infertile men. (PubMed id 17114206)^{1, 3, 4} Kostova E....Gromoll J. (2007)
Mutations in the human BOULE gene are not a major cause of impaired spermatogenesis. (PubMed id 15705409)^{3, 6} Westerveld G.H....Lombardi M.P. (2005)
The DAZL family proteins are PABP-binding proteins that regulate translation in germ cells. (PubMed id 16001084)^{2, 3} Collier B....Gray N.K. (2005)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
Mutation analysis of the BOULE gene in men with non-obstructive azoospermia: identification of a novel polymorphic variant in the black population. (PubMed id 15379971)^{3, 6} Lepretre A.C....Bienvenu T. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Association of meiotic arrest with lack of BOULE protein expression in infertile men. (PubMed id 15070965)^{1, 3} Luetjens C.M....Gromoll J. (2004)
Expression profiles of the DAZ gene family in human testis with and without spermatogenic failure. (PubMed id 15066460)^{1, 3} Kuo P.L....Hsu C.C. (2004)
Human BOULE gene rescues meiotic defects in infertile flies. (PubMed id 12499397)^{1, 3} Xu E.Y....Reijo Pera R.A. (2003)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 66037	HGNC: 14273	AceView: BOLL	Ensembl:ENSG00000152430	euGenes: HUgn66037
ECgene: BOLL	H-InvDB: BOLL

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for BOLL
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for BOLL:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for BOLL-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for BOLL		Antibodies for BOLL
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for BOLL		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (BOLL)
	Antibodies (BOLL)
	Chimera RNAi (BOLL)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

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	Antibodies (BOULE)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for BOLL

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for BOLL

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BOLL Gene

protein-coding GIFtS: 54

Aliases &
Descriptions
for BOLL

Summaries
for BOLL

Genomic Location
for BOLL

Proteins
for BOLL

Protein Domains/
Families
for BOLL

Gene Function
for BOLL

Pathways & Interactions
for BOLL

Drugs & Compounds
for BOLL

Transcripts
for BOLL

Expression
for BOLL

Orthologs
for BOLL

Paralogs
for BOLL

SNPs/Variants
for BOLL

Disorders & Mutations
for BOLL

Medical News
for BOLL

Publications
for BOLL

Search for BOLL

Genome Databases showing BOLL

Other Databases showing BOLL

Specialized Databases showing BOLL

Licensable Technologies
for BOLL

Services
for BOLL

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

BOLL Gene

protein-coding GIFtS: 54

Aliases & Descriptionsfor BOLL

Summariesfor BOLL

Genomic Locationfor BOLL

Proteinsfor BOLL

Protein Domains/Familiesfor BOLL

Gene Functionfor BOLL

Pathways & Interactionsfor BOLL

Drugs & Compoundsfor BOLL

Transcriptsfor BOLL

Expression for BOLL

Orthologsfor BOLL

Paralogsfor BOLL

SNPs/Variantsfor BOLL

Disorders & Mutationsfor BOLL

Medical Newsfor BOLL

Publicationsfor BOLL

Search for BOLL

Genome Databases showing BOLL

Other Databases showing BOLL

Specialized Databases showing BOLL

Licensable Technologiesfor BOLL

Servicesfor BOLL

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for BOLL

Summaries
for BOLL

Genomic Location
for BOLL

Proteins
for BOLL

Protein Domains/
Families
for BOLL

Gene Function
for BOLL

Pathways & Interactions
for BOLL

Drugs & Compounds
for BOLL

Transcripts
for BOLL

Expression
for BOLL

Orthologs
for BOLL

Paralogs
for BOLL

SNPs/Variants
for BOLL

Disorders & Mutations
for BOLL

Medical News
for BOLL

Publications
for BOLL

Licensable Technologies
for BOLL

Services
for BOLL